Peripherally acting mu-opioid receptor antagonists and postoperative ileus: Mechanisms of action and clinical applicability

Anesthesia and Analgesia

Volumn 108, Issue 6, 2009, Pages 1811-1822

  Viscusi, Eugene R ^a   Gan, Tong J ^b   Leslie, John B ^c   Foss, Joseph F ^d   Talon, Mark D ^e   Du, Wei ^f   Owens, Gay ^f  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

^c Mayo Clinic   (United States)

^d LERNER RESEARCH INSTITUTE   (United States)

^e University of Texas Medical Branch School of Medicine   (United States)

^f ADOLOR CORPORATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

17 METHYLNALTREXONE; ALVIMOPAN; MORPHINE; MU OPIATE RECEPTOR ANTAGONIST; NALTREXONE; MU OPIATE RECEPTOR; NARCOTIC ANALGESIC AGENT; NARCOTIC ANTAGONIST; OPIATE RECEPTOR;

ABDOMINAL CRAMP; ABDOMINAL DISTENSION; CARDIOVASCULAR DISEASE; COLON RESECTION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG CONTRAINDICATION; DRUG EFFICACY; DRUG INDICATION; DRUG MECHANISM; DRUG RECEPTOR BINDING; DRUG SAFETY; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG TOLERABILITY; FEVER; GASTROINTESTINAL MOTILITY; HUMAN; HYPERTENSION; ILEUS; INTERNEURON; INTESTINE INNERVATION; INTESTINE RESECTION; MOTONEURON; NAUSEA; NEUROPHYSIOLOGY; ORTHOSTATIC HYPOTENSION; PAIN ASSESSMENT; POSTOPERATIVE COMPLICATION; PREOPERATIVE PERIOD; PRIORITY JOURNAL; REVIEW; SENSORY NERVE CELL; STEADY STATE; VOMITING; ANIMAL; CHEMICALLY INDUCED DISORDER; DRUG EFFECT; DRUG POTENTIATION; PERIPHERAL NERVOUS SYSTEM; PHYSIOLOGY;

ANALGESICS, OPIOID; ANIMALS; ENTERIC NERVOUS SYSTEM; HUMANS; ILEUS; NARCOTIC ANTAGONISTS; PERIPHERAL NERVOUS SYSTEM; POSTOPERATIVE COMPLICATIONS; RECEPTORS, OPIOID; RECEPTORS, OPIOID, MU;

EID: 66349134446     PISSN: 00032999     EISSN: None     Source Type: Journal    
DOI: 10.1213/ane.0b013e31819e0d3a     Document Type: Review

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