메뉴 건너뛰기




Volumn 40, Issue 6, 2005, Pages 176-183

Alvimopan: A peripherally selective opioid mu receptor antagonist

Author keywords

[No Author keywords available]

Indexed keywords

ALVIMOPAN; MU OPIATE RECEPTOR ANTAGONIST; OPIATE; OPIATE RECEPTOR;

EID: 21744445222     PISSN: 1082801X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (7)

References (11)
  • 1
    • 0037249711 scopus 로고    scopus 로고
    • Opioid-induced bowel dysfunction
    • Kurz A, Sessler DI. Opioid-induced bowel dysfunction. Drugs. 2003;63(7):649-671.
    • (2003) Drugs , vol.63 , Issue.7 , pp. 649-671
    • Kurz, A.1    Sessler, D.I.2
  • 2
    • 0035543168 scopus 로고    scopus 로고
    • Alvimopan (ADL-8-2698) is a novel peripheral opioid antagonist
    • Schmidt WK. Alvimopan (ADL-8-2698) is a novel peripheral opioid antagonist. Am J Surg. 2001;182(Suppl to November 2001):27S-38S.
    • (2001) Am J Surg , vol.182 , Issue.SUPPL. TO NOVEMBER 2001
    • Schmidt, W.K.1
  • 4
    • 0028592497 scopus 로고
    • LY246736 dihydrate. Mu opioid receptor antagonist
    • Zimmerman DM, Gidda JS, Cantrell BE, et al. LY246736 Dihydrate. Mu opioid receptor antagonist. Drugs Future. 1994;19:1078-1083.
    • (1994) Drugs Future , vol.19 , pp. 1078-1083
    • Zimmerman, D.M.1    Gidda, J.S.2    Cantrell, B.E.3
  • 5
    • 0027930289 scopus 로고
    • Discovery of a potent, peripherally selective trans-3,4-dimethyl-4-(3- hydroxyphenyl) piperidine opioid antagonist for the treatment of gastrointestinal motility disorders
    • Zimmerman DM, Gidda JS, Cantrell BE, et al. Discovery of a potent, peripherally selective trans-3,4-dimethyl-4-(3-hydroxyphenyl) piperidine opioid antagonist for the treatment of gastrointestinal motility disorders. J Med Chem. 1994;37:2262-2265.
    • (1994) J Med Chem , vol.37 , pp. 2262-2265
    • Zimmerman, D.M.1    Gidda, J.S.2    Cantrell, B.E.3
  • 6
    • 0035138992 scopus 로고    scopus 로고
    • ADL 8-2698, a trans-3,4-dimethyl-4-(3-hydroxyphenyl) piperidine, prevents gastrointestinal effects of intravenous morphine without affecting analgesia
    • Liu SS, Hodgeson PS, Carpenter RL, Fricke JR. ADL 8-2698, a trans-3,4-dimethyl-4-(3-hydroxyphenyl) piperidine, prevents gastrointestinal effects of intravenous morphine without affecting analgesia. Clin Pharmacol Ther. 2001;69(1):66-71.
    • (2001) Clin Pharmacol Ther , vol.69 , Issue.1 , pp. 66-71
    • Liu, S.S.1    Hodgeson, P.S.2    Carpenter, R.L.3    Fricke, J.R.4
  • 7
    • 0035960121 scopus 로고    scopus 로고
    • Selective postoperative inhibition of gastrointestinal opioid receptors
    • Taguchi A, Sharma W, Saleem RM, et al. Selective postoperative inhibition of gastrointestinal opioid receptors. N Engl J Med. 2001;345(13):935-940.
    • (2001) N Engl J Med , vol.345 , Issue.13 , pp. 935-940
    • Taguchi, A.1    Sharma, W.2    Saleem, R.M.3
  • 8
    • 21744452323 scopus 로고    scopus 로고
    • Prospective, randomized, double-blind, multicenter, placebo-controlled study of alvimopan, a novel peripherally-acting mu opioid antagonist for postoperative ileus after major abdominal surgery
    • Delaney C, Weese J, Hyman N. Prospective, randomized, double-blind, multicenter, placebo-controlled study of alvimopan, a novel peripherally-acting mu opioid antagonist for postoperative ileus after major abdominal surgery [abstract]. Dis Colon Rectum. 2004;47:589.
    • (2004) Dis Colon Rectum , vol.47 , pp. 589
    • Delaney, C.1    Weese, J.2    Hyman, N.3
  • 9
    • 4644311821 scopus 로고    scopus 로고
    • Alvimopan, a novel peripherally acting mu opioid antagonist; results of a multicenter, randomized, double-blind, placebo-controlled, phase III trial of major abdominal surgery and postoperative ileus
    • Wolff BG, Michelassi F, Gerkin TM, et al. Alvimopan, a novel peripherally acting mu opioid antagonist; results of a multicenter, randomized, double-blind, placebo-controlled, Phase III trial of major abdominal surgery and postoperative ileus. Ann Surg. 2004;240(4):728-735.
    • (2004) Ann Surg , vol.240 , Issue.4 , pp. 728-735
    • Wolff, B.G.1    Michelassi, F.2    Gerkin, T.M.3
  • 10
    • 14944349101 scopus 로고    scopus 로고
    • Effects of ADL 8-2698, a peripherally restricted mu opioid antagonist, on gut mobility in methadone and LAAM dependent patients with opioid-induced constipation: A dose ranging study
    • Liberto JG, Herschler JA, Jaffe JH, et al. Effects of ADL 8-2698, a peripherally restricted mu opioid antagonist, on gut mobility in methadone and LAAM dependent patients with opioid-induced constipation: a dose ranging study [abstract]. Drug Alcohol Depend. 2001;63:591.
    • (2001) Drug Alcohol Depend. , vol.63 , pp. 591
    • Liberto, J.G.1    Herschler, J.A.2    Jaffe, J.H.3
  • 11
    • 20144366569 scopus 로고    scopus 로고
    • An oral, peripherally acting, mu opioid receptor antagonist for the treatment of opioid-induced bowel dysfunction for the treatment of opioid induced bowel dysfunction-a 21-day treatment-randomized clinical trial
    • Paulson DM, Kennedy DT, Donovick RA, et al. An oral, peripherally acting, mu opioid receptor antagonist for the treatment of opioid-induced bowel dysfunction for the treatment of opioid induced bowel dysfunction-a 21-day treatment-randomized clinical trial. J Pain. 2004;6(3):184-192.
    • (2004) J Pain , vol.6 , Issue.3 , pp. 184-192
    • Paulson, D.M.1    Kennedy, D.T.2    Donovick, R.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.