Pathogenesis and clinical and economic consequences of postoperative ileus

American Journal of Health-System Pharmacy

Volumn 64, Issue 20 SUPPL., 2007, Pages

  Senagore, Anthony J ^a,b  

^a MICHIGAN STATE UNIVERSITY   (United States)

^b SPECTRUM HEALTH   (United States)

Author keywords

Economics; Hospitals; Ileus; Opiates; Patient information; Postoperative complications; Toxicity

Indexed keywords

ALVIMOPAN;

ABDOMINAL DISCOMFORT; ABDOMINAL SURGERY; CLINICAL FEATURE; CONFERENCE PAPER; COST OF ILLNESS; DEEP VEIN THROMBOSIS; DISEASE CLASSIFICATION; HUMAN; ILEUS; LENGTH OF STAY; NAUSEA; PAIN; PATHOPHYSIOLOGY; PNEUMONIA; POSTOPERATIVE ANALGESIA; PRIORITY JOURNAL; RISK FACTOR; VOMITING; WOUND HEALING IMPAIRMENT;

EID: 35348923756     PISSN: 10792082     EISSN: None     Source Type: Journal    
DOI: 10.2146/ajhp070428     Document Type: Conference Paper

References (25)

1. Holte K, Kehlet H. Postoperative ileus: progress towards effective management. Drugs. 2002; 62:2603-15.
2. Kehlet H, Holte K. Review of postoperative ileus. Am J Surg. 2001; 182(5A suppl):3S-10S.
3. Holte K, Kehlet H. Postoperative ileus: a preventable event. Br J Surg. 2000; 87:1480-93.
4. Brix-Christensen V, Tonnesen E, Sanchez RG et al. Endogenous morphine levels increase following cardiac surgery as part of the anti-inflammatory response? Int J Cardiol. 1997; 62:191-7.
5. Yoshida S, Ohta J, Yamasaki K et al. Effect of surgical stress on endogenous morphine and cytokine levels in the plasma after laparoscopic or open cholecystectomy. Surg Endosc. 2000; 14:137-40.
6. Kalff JC, Schraut WH, Simmons RL et al. Surgical manipulation of the gut elicits an intestinal muscularis inflammatory response resulting in postsurgical ileus. Ann Surg. 1998; 228:652-63.
7. Taché Y, Bonaz B. Corticotropin-releasing factor receptors and stress-related alterations of gut motor function. J Clin Invest. 2007; 117:33-40.
8. Behm B, Stollman N. Postoperative ileus: etiologies and interventions. Clin Gastroenterol Hepatol. 2003; 1:71-80.
9. Delaney CP, Fazio VW, Senagore AJ et al. 'Fast track' postoperative management protocol for patients with high co-morbidity undergoing complex abdominal and pelvic colorectal surgery. Br J Surg. 2001; 88:1533-8.
10. Wolff BG, Michelassi F, Gerkin TM et al. Alvimopan, a novel, peripherally acting mu opioid antagonist: results of a multicenter, randomized, double-blind, placebo-controlled, phase III trial of major abdominal surgery and postoperative ileus. Ann Surg. 2004; 240:728-34.
11. Cali RL, Meade PG, Swanson MS et al. Effect of morphine and incision length on bowel function after colectomy. Dis Colon Rectum. 2000; 43:163-8.
12. Kraft M, Erstad BL, Matuszewski K. Improving postoperative ileus outcomes. US Pharmacist. 2005; http://www.uspharmacist.com/index.asp? page=ce/10193/default.htm (accessed 2007 Mar 6).
13. Steinbrook RA. Epidural anesthesia and gastrointestinal motility. Anesth Analg. 1998; 86:837-44.
14. Hong X, Mistraletti G, Zandi S. Laparoscopy for colectomy accelerates restoration of bowel function when using patient controlled analgesia. Can J Anesth. 2006; 53:544-50.
15. Collins TC, Daley J, Henderson WH et al. Risk factors for prolonged length of stay after major elective surgery. Ann Surg. 1999; 230:251-9.
16. Schuster TG, Montie JE. Postoperative ileus after abdominal surgery. Urology. 2002; 59:465-71.
17. Chang SS, Baumgartner RG, Wells N et al. Causes of increased hospital stay after radical cystectomy in a clinical pathway setting. J Urol. 2002; 167:208-11.
18. Lauer MA, Karweit JA, Cascade EF et al. Practice patterns and outcomes of percutaneous coronary interventions in the United States: 1995 to 1997. Am J Cardiol. 2002; 89:924-9.
19. Woods MS. Postoperative ileus: dogma versus data from bench to bedside. Perspect Colon Rectal Surg. 2000; 12:57-76.
20. Delaney CP. Clinical perspective on postoperative ileus and the effect of opiates. Neurogastroenterol Motil. 2004; 16 suppl 2:61-6.
21. Saunders WB, Bowers B, Moss B et al. Recorded rate and economic burden associated with postoperative ileus. Presented at the ASHP Midyear Clinical Meeting. Orlando, FL: December 7, 2004. Abstract 30346.
22. Salvador CG, Sikirica M, Evans E et al. Clinical and economic outcomes of patients with prolonged postoperative ileus undergoing hysterectomy and hemicolectomy at an academic medical institution. Presented at the ASHP Midyear Clinical Meeting. Orlando, FL: December 7, 2004. Abstract 30183.
23. Kehlet H, Dahl JB. Anaesthesia, surgery, and challenges in postoperative recovery. Lancet. 2003; 362:1921-8.
24. Ditmyer MM, Topp R, Pifer M. rehabilitation in preparation for orthopaedic surgery. Orthop Nurs. 2002; 21:43-51.
25. Holzer P. Opioids and opioid receptors in the enteric nervous system: from a problem in opioid analgesia to a possible new prokinetic therapy in humans. Neurosci Lett. 2004; 361:192-5.