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Volumn 29, Issue 10, 2009, Pages 2609-2621

Polo-like kinase 1 depletion induces DNA damage in early S prior to caspase activation

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; GEMININ; LENTIVIRUS VECTOR; POLO LIKE KINASE 1; PROTEIN INHIBITOR; SMALL INTERFERING RNA; CASPASE; CELL CYCLE PROTEIN; DNA; DNA BINDING PROTEIN; F BOX PROTEIN; FBXO5 PROTEIN, HUMAN; GMNN PROTEIN, HUMAN; H2AFX PROTEIN, HUMAN; HISTONE; MADS DOMAIN PROTEIN; NUCLEAR PROTEIN; ONCOPROTEIN; POLO-LIKE KINASE 1; PROTEIN P53; PROTEIN SERINE THREONINE KINASE; TUMOR SUPPRESSOR PROTEIN; TUMOR SUPPRESSOR PROTEIN P73;

EID: 66349094331     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.01277-08     Document Type: Article
Times cited : (70)

References (41)
  • 1
    • 0034520085 scopus 로고    scopus 로고
    • Dominant-negative polo-like kinase 1 induces mitotic catastrophe independent of cdc25c function
    • Cogswell, J. P., C. E. Brown, J. E. Bisi, and S. D. Neill. 2000. Dominant-negative polo-like kinase 1 induces mitotic catastrophe independent of cdc25c function. Cell Growth Differ. 11:615-623.
    • (2000) Cell Growth Differ , vol.11 , pp. 615-623
    • Cogswell, J.P.1    Brown, C.E.2    Bisi, J.E.3    Neill, S.D.4
  • 2
    • 4544221279 scopus 로고    scopus 로고
    • Regulation of early events in chromosome replication
    • Diffley, J. F. 2004. Regulation of early events in chromosome replication. Curr. Biol. 14:R778-R786.
    • (2004) Curr. Biol , vol.14
    • Diffley, J.F.1
  • 3
    • 13244269808 scopus 로고    scopus 로고
    • Polo-like kinase and oncogenesis
    • Eckerdt, F., J. Yuan, and K. Strebhardt. 2005. Polo-like kinase and oncogenesis. Oncogene 24:267-276.
    • (2005) Oncogene , vol.24 , pp. 267-276
    • Eckerdt, F.1    Yuan, J.2    Strebhardt, K.3
  • 4
    • 38949099707 scopus 로고    scopus 로고
    • The ubiquitin ligase APC (Cdh1) is required to maintain genome integrity in primary human cells
    • Engelbert, D., D. Schnerch, A. Baumgarten, and R. Wäsch. 2008. The ubiquitin ligase APC (Cdh1) is required to maintain genome integrity in primary human cells. Oncogene 27:907-917.
    • (2008) Oncogene , vol.27 , pp. 907-917
    • Engelbert, D.1    Schnerch, D.2    Baumgarten, A.3    Wäsch, R.4
  • 5
    • 0037041392 scopus 로고    scopus 로고
    • p63 and p73 are required for p53-dependent apoptosis in response to DNA damage
    • Flores, E. R., K. Y. Tsai, D. Crowley, S. Sengupta, A. Yang, F. Mckeon, and T. Jacks. 2002. p63 and p73 are required for p53-dependent apoptosis in response to DNA damage. Nature 416:560-564.
    • (2002) Nature , vol.416 , pp. 560-564
    • Flores, E.R.1    Tsai, K.Y.2    Crowley, D.3    Sengupta, S.4    Yang, A.5    Mckeon, F.6    Jacks, T.7
  • 6
    • 33746379285 scopus 로고    scopus 로고
    • APC/C-mediated degradation in early mitosis
    • Fry, A. M., and H. Yamano. 2006. APC/C-mediated degradation in early mitosis. Cell Cycle 14:1487-1491.
    • (2006) Cell Cycle , vol.14 , pp. 1487-1491
    • Fry, A.M.1    Yamano, H.2
  • 7
    • 13244259198 scopus 로고    scopus 로고
    • Polo kinase and progression through M phase in Drosophila: A perspective from the spindle poles
    • Glover, D. M. 2005. Polo kinase and progression through M phase in Drosophila: a perspective from the spindle poles. Oncogene 24:230-237.
    • (2005) Oncogene , vol.24 , pp. 230-237
    • Glover, D.M.1
  • 8
    • 0029079267 scopus 로고
    • Cell cycle regulation of activity and subcellular localization of Plk1, a human protein kinase implicated in mitotic spindle function
    • Golsteyn, R. M., K. E. Mundt, A. M. Fry, and E. A. Nigg. 1995. Cell cycle regulation of activity and subcellular localization of Plk1, a human protein kinase implicated in mitotic spindle function. J. Cell Biol. 129:1617-1628.
    • (1995) J. Cell Biol , vol.129 , pp. 1617-1628
    • Golsteyn, R.M.1    Mundt, K.E.2    Fry, A.M.3    Nigg, E.A.4
  • 9
    • 0027977923 scopus 로고
    • Cloning and characterization of human and murine homologues of the Drosophila polo serine-threonine kinase
    • Hamanaka, R., S. Maloid, M. R. Smith, C. D. O'Connell, D. L. Longo, and D. K. Ferris. 1994. Cloning and characterization of human and murine homologues of the Drosophila polo serine-threonine kinase. Cell Growth Differ. 5:249-257.
    • (1994) Cell Growth Differ , vol.5 , pp. 249-257
    • Hamanaka, R.1    Maloid, S.2    Smith, M.R.3    O'Connell, C.D.4    Longo, D.L.5    Ferris, D.K.6
  • 10
    • 9444235650 scopus 로고    scopus 로고
    • Plk1 regulates activation of the anaphase promoting complex by phosphorylating and triggering SCFbetaTrCP-dependent destruction of the APC inhibitor Emi1
    • Hansen, D. V., A. V. Loktev, K. H. Ban, and P. K. Jackson. 2004. Plk1 regulates activation of the anaphase promoting complex by phosphorylating and triggering SCFbetaTrCP-dependent destruction of the APC inhibitor Emi1. Mol. Biol. Cell 15:5623-5624.
    • (2004) Mol. Biol. Cell , vol.15 , pp. 5623-5624
    • Hansen, D.V.1    Loktev, A.V.2    Ban, K.H.3    Jackson, P.K.4
  • 11
    • 0034609798 scopus 로고    scopus 로고
    • Irwin, M., M. C. Marin, A. C. Phillips, R. S. Seelan, D. I. Smith, W. Liu, E. R. Flores, K. Y. Tsai, T. Jacks, K. H. Vousden, and W. G. Kaelin, Jr. 2000. Role for the p53 homologue p73 in E2F-1-induced apoptosis. Nature 407:645-648.
    • Irwin, M., M. C. Marin, A. C. Phillips, R. S. Seelan, D. I. Smith, W. Liu, E. R. Flores, K. Y. Tsai, T. Jacks, K. H. Vousden, and W. G. Kaelin, Jr. 2000. Role for the p53 homologue p73 in E2F-1-induced apoptosis. Nature 407:645-648.
  • 12
    • 0037113919 scopus 로고    scopus 로고
    • Phosphorylation of threonine 210 and the role of serine 137 in the regulation of mammalian polo-like kinase
    • Jang, Y.-J., S. Ma, Y. Terada, and R. L. Erikson. 2002. Phosphorylation of threonine 210 and the role of serine 137 in the regulation of mammalian polo-like kinase. J. Biol. Chem. 277:44115-44120.
    • (2002) J. Biol. Chem , vol.277 , pp. 44115-44120
    • Jang, Y.-J.1    Ma, S.2    Terada, Y.3    Erikson, R.L.4
  • 13
    • 43749113592 scopus 로고    scopus 로고
    • Inhibitory role of Plk1 in the regulation of p73-dependent apoptosis through physical interaction and phosphorylation
    • Koida, N., T. Ozaki, H. Yamamoto, S. Ono, T. Koda, K. Ando, R. Okoshi, T. Kamijo, K. Omura, and A. Nakagawara. 2008. Inhibitory role of Plk1 in the regulation of p73-dependent apoptosis through physical interaction and phosphorylation. J. Biol. Chem. 283:8555-8563.
    • (2008) J. Biol. Chem , vol.283 , pp. 8555-8563
    • Koida, N.1    Ozaki, T.2    Yamamoto, H.3    Ono, S.4    Koda, T.5    Ando, K.6    Okoshi, R.7    Kamijo, T.8    Omura, K.9    Nakagawara, A.10
  • 14
    • 0029821131 scopus 로고    scopus 로고
    • Purification and molecular cloning of Plx1, a Cdc25-regulatory kinase from Xenopus egg extracts
    • Kumagai, A., and W. G. Dunphy. 1996. Purification and molecular cloning of Plx1, a Cdc25-regulatory kinase from Xenopus egg extracts. Science 273: 1377-1380.
    • (1996) Science , vol.273 , pp. 1377-1380
    • Kumagai, A.1    Dunphy, W.G.2
  • 15
    • 0030462914 scopus 로고    scopus 로고
    • Antibody microinjection reveals an essential role for human polo-like kinase 1 (Plk1) in the functional maturation of mitotic centrosome
    • Lane, H. A., and E. A. Nigg. 1996. Antibody microinjection reveals an essential role for human polo-like kinase 1 (Plk1) in the functional maturation of mitotic centrosome. J. Cell Biol. 135:1701-1713.
    • (1996) J. Cell Biol , vol.135 , pp. 1701-1713
    • Lane, H.A.1    Nigg, E.A.2
  • 16
    • 38949199337 scopus 로고    scopus 로고
    • HDM2 antagonist Nutlin-3 disrupts p73-HDM2 binding and enhances p73 function
    • Lau, L. M., J. K. Nugent, X. Zhao, and M. S. Irwin. 2008. HDM2 antagonist Nutlin-3 disrupts p73-HDM2 binding and enhances p73 function. Oncogene 27:997-1003.
    • (2008) Oncogene , vol.27 , pp. 997-1003
    • Lau, L.M.1    Nugent, J.K.2    Zhao, X.3    Irwin, M.S.4
  • 17
    • 33644767315 scopus 로고    scopus 로고
    • Normal cells, but not cancer cells, survive severe Plk1 depletion
    • Liu, X., M. Lei, and R. L. Erikson. 2006. Normal cells, but not cancer cells, survive severe Plk1 depletion. Mol. Cell. Biol. 26:2093-2108.
    • (2006) Mol. Cell. Biol , vol.26 , pp. 2093-2108
    • Liu, X.1    Lei, M.2    Erikson, R.L.3
  • 18
    • 0038624074 scopus 로고    scopus 로고
    • Polo-like kinase (Plk)1 depletion induces apoptosis in cancer cells
    • Liu, X., and R. L. Erikson. 2003. Polo-like kinase (Plk)1 depletion induces apoptosis in cancer cells. Proc. Natl. Acad. Sci. USA 100:5789-5794.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 5789-5794
    • Liu, X.1    Erikson, R.L.2
  • 19
    • 0037534899 scopus 로고    scopus 로고
    • Prophase destruction of Emi1 by the SCF (betaTrCP/Slimb) ubiquitin ligase activates the anaphase promoting complex to allow progression beyond prometaphase
    • Margottin-Goguet, F., J. Y. Hsu, A. Loktev, H. M. Hsieh, J. D. Reimann, and P. K. Jackson. 2003. Prophase destruction of Emi1 by the SCF (betaTrCP/Slimb) ubiquitin ligase activates the anaphase promoting complex to allow progression beyond prometaphase. Dev. Cell 4:813-826.
    • (2003) Dev. Cell , vol.4 , pp. 813-826
    • Margottin-Goguet, F.1    Hsu, J.Y.2    Loktev, A.3    Hsieh, H.M.4    Reimann, J.D.5    Jackson, P.K.6
  • 21
    • 33645739658 scopus 로고    scopus 로고
    • The alkaline comet assay: Towards validation in biomonitoring of DNA damaging exposures
    • Moller, P. 2006. The alkaline comet assay: towards validation in biomonitoring of DNA damaging exposures. Basic Clin. Pharmacol. Toxicol. 98:336-345.
    • (2006) Basic Clin. Pharmacol. Toxicol , vol.98 , pp. 336-345
    • Moller, P.1
  • 22
    • 2542617641 scopus 로고    scopus 로고
    • Role of Polo-like kinase in the degradation of early mitotic inhibitor 1, a regulator of the anaphase promoting complex/cyclosome
    • Moshe, Y., J. Boulaire, M. Pagano, and A. Hershko. 2004. Role of Polo-like kinase in the degradation of early mitotic inhibitor 1, a regulator of the anaphase promoting complex/cyclosome. Proc. Natl. Acad. Sci. USA 101: 7937-7942.
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 7937-7942
    • Moshe, Y.1    Boulaire, J.2    Pagano, M.3    Hershko, A.4
  • 23
    • 0035422288 scopus 로고    scopus 로고
    • Stability, chromatin association and functional activity of mammalian prereplicative complex proteins during the cell cycle
    • Okuno, Y., A. J. McNairn, N. den Elzen, J. Pines, and D. M. Gilbert. 2001. Stability, chromatin association and functional activity of mammalian prereplicative complex proteins during the cell cycle. EMBO J. 20:4263-4277.
    • (2001) EMBO J , vol.20 , pp. 4263-4277
    • Okuno, Y.1    McNairn, A.J.2    den Elzen, N.3    Pines, J.4    Gilbert, D.M.5
  • 24
    • 41649120947 scopus 로고    scopus 로고
    • Interplay between ATM and ATR in the regulation of common fragile site stability
    • Ozeri-Galai, E., M. Schwartz, A. Rahar, and B. Kerem. 2008. Interplay between ATM and ATR in the regulation of common fragile site stability. Oncogene 27:2109-2117.
    • (2008) Oncogene , vol.27 , pp. 2109-2117
    • Ozeri-Galai, E.1    Schwartz, M.2    Rahar, A.3    Kerem, B.4
  • 25
    • 3342926035 scopus 로고    scopus 로고
    • Human Orc2 localizes to centrosomes, centromeres and heterochromatin during chromosome inheritance
    • Prasanth, S. G., K. V. Prasanth, K. Siddiqui, D. L. Spector, and B. Stillman. 2004. Human Orc2 localizes to centrosomes, centromeres and heterochromatin during chromosome inheritance. EMBO J. 23:2651-2663.
    • (2004) EMBO J , vol.23 , pp. 2651-2663
    • Prasanth, S.G.1    Prasanth, K.V.2    Siddiqui, K.3    Spector, D.L.4    Stillman, B.5
  • 26
    • 0035370009 scopus 로고    scopus 로고
    • Emi1 is a mitotic regulator that interacts with Cdc20 and inhibits the anaphase promoting complex
    • Reimann, J. D., E. Freed, J. Y. Hsu, E. R. Kramer, J. M. Peters, and P. K. Jackson. 2001. Emi1 is a mitotic regulator that interacts with Cdc20 and inhibits the anaphase promoting complex. Cell 105:645-655.
    • (2001) Cell , vol.105 , pp. 645-655
    • Reimann, J.D.1    Freed, E.2    Hsu, J.Y.3    Kramer, E.R.4    Peters, J.M.5    Jackson, P.K.6
  • 27
    • 33747884339 scopus 로고    scopus 로고
    • DNA damage-induced cell death by apoptosis
    • Roos, W. P., and B. Kaina. 2006. DNA damage-induced cell death by apoptosis. Trends Mol. Med. 12:1471-1476.
    • (2006) Trends Mol. Med , vol.12 , pp. 1471-1476
    • Roos, W.P.1    Kaina, B.2
  • 28
    • 0037179866 scopus 로고    scopus 로고
    • Cell type-specific responses of human cells to inhibition of replication licensing
    • Shreeram, S., A. Sparks, D. P. Lane, and J. J. Blow. 2002. Cell type-specific responses of human cells to inhibition of replication licensing. Oncogene 21:6624-6632.
    • (2002) Oncogene , vol.21 , pp. 6624-6632
    • Shreeram, S.1    Sparks, A.2    Lane, D.P.3    Blow, J.J.4
  • 30
    • 0038752083 scopus 로고    scopus 로고
    • Chk2 activates E2F-1 in response to DNA damage
    • Stevens, C., L. Smith, and N. B. La Thangue. 2003. Chk2 activates E2F-1 in response to DNA damage. Nat. Cell Biol. 5:401-409.
    • (2003) Nat. Cell Biol , vol.5 , pp. 401-409
    • Stevens, C.1    Smith, L.2    La Thangue, N.B.3
  • 34
    • 40949133430 scopus 로고    scopus 로고
    • Plx1 is required for chromosomal DNA replication under stressful conditions
    • Trenz, K., A. Errico, and V. Costanzo. 2008. Plx1 is required for chromosomal DNA replication under stressful conditions. EMBO J. 27:876-885.
    • (2008) EMBO J , vol.27 , pp. 876-885
    • Trenz, K.1    Errico, A.2    Costanzo, V.3
  • 35
    • 15744400904 scopus 로고    scopus 로고
    • Interaction of chromatin-associated Plk1 and Mcm7
    • Tsvetkov, L., and D. F. Stern. 2005. Interaction of chromatin-associated Plk1 and Mcm7. J. Biol. Chem. 280:11943-11947.
    • (2005) J. Biol. Chem , vol.280 , pp. 11943-11947
    • Tsvetkov, L.1    Stern, D.F.2
  • 36
    • 10644270921 scopus 로고    scopus 로고
    • p73 induction after DNA damage is regulated by checkpoint kinases Chk1 and Chk2
    • Urist, M., T. Tanaka, M. V. Poyurovsky, and C. Prives. 2004. p73 induction after DNA damage is regulated by checkpoint kinases Chk1 and Chk2. Genes Dev. 28:3041-3054.
    • (2004) Genes Dev , vol.28 , pp. 3041-3054
    • Urist, M.1    Tanaka, T.2    Poyurovsky, M.V.3    Prives, C.4
  • 37
    • 18344366048 scopus 로고    scopus 로고
    • Getting in and out of mitosis with Polo-like kinase-1
    • van Vugt, M. A. T. M., and R. H. Medema. 2005. Getting in and out of mitosis with Polo-like kinase-1. Oncogene 24:2844-2859.
    • (2005) Oncogene , vol.24 , pp. 2844-2859
    • van Vugt, M.A.T.M.1    Medema, R.H.2
  • 38
    • 4344718620 scopus 로고    scopus 로고
    • Polo-like kinase-1 is required for bipolar spindle formation but is dispensable for anaphase promoting complex/cdc20 activation and initiation of cytokinesis
    • van Vugt, M. A. T. M., B. C. M. van de Weerdt, G. Vader, H. Janssen, J. Calafat, R. Klompmaker, R. M. F. Wolthuis, and R. H. Medema. 2004. Polo-like kinase-1 is required for bipolar spindle formation but is dispensable for anaphase promoting complex/cdc20 activation and initiation of cytokinesis. J. Biol. Chem. 279:36841-36853.
    • (2004) J. Biol. Chem , vol.279 , pp. 36841-36853
    • van Vugt, M.A.T.M.1    van de Weerdt, B.C.M.2    Vader, G.3    Janssen, H.4    Calafat, J.5    Klompmaker, R.6    Wolthuis, R.M.F.7    Medema, R.H.8
  • 39
    • 41149134864 scopus 로고    scopus 로고
    • Role for Plk1 phosphorylation of Hbo1 in regulation of replication licensing
    • Wu, Z., and X. Liu. 2008. Role for Plk1 phosphorylation of Hbo1 in regulation of replication licensing. Proc. Natl. Acad. Sci. USA 105:1919-1924.
    • (2008) Proc. Natl. Acad. Sci. USA , vol.105 , pp. 1919-1924
    • Wu, Z.1    Liu, X.2
  • 40
    • 47949129452 scopus 로고    scopus 로고
    • Induction of a pro-apoptotic ARM-NF-κB pathway and its repression by ATR in response to replication stress
    • Wu, Z.-H., and S. Miyamoto. 2008. Induction of a pro-apoptotic ARM-NF-κB pathway and its repression by ATR in response to replication stress. EMBO J. 27:1963-1973.
    • (2008) EMBO J , vol.27 , pp. 1963-1973
    • Wu, Z.-H.1    Miyamoto, S.2
  • 41
    • 33745592177 scopus 로고    scopus 로고
    • Cleavage of Cdc6 by caspase-3 promotes ATM/ATR kinase-mediated apoptosis of HeLa cells
    • Yim, H., I. S. Hwang, J. S. Choi, K. H. Chun, Y. H. Jin, Y. M. Ham, K. Y. Lee, and S. K. Lee. 2006. Cleavage of Cdc6 by caspase-3 promotes ATM/ATR kinase-mediated apoptosis of HeLa cells. J. Cell Biol. 174:77-88.
    • (2006) J. Cell Biol , vol.174 , pp. 77-88
    • Yim, H.1    Hwang, I.S.2    Choi, J.S.3    Chun, K.H.4    Jin, Y.H.5    Ham, Y.M.6    Lee, K.Y.7    Lee, S.K.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.