Synthesis of novel retinoid X receptor-selective retinoids

Journal of Organic Chemistry

Volumn 66, Issue 17, 2001, Pages 5772-5782

  Faul, M M ^a   Ratz, A M ^a   Sullivan, K A ^a   Trankle, W G ^a   Winneroski, L L ^a  

^a ELI LILLY AND COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CONVERGENT SYNTHESES;

ALKYLATION; DEHYDRATION; FRIEDEL-CRAFTS REACTION; INSULIN; SAPONIFICATION; TOLUENE;

SYNTHESIS (CHEMICAL);

4 [1 (3,5,5,8,8 PENTAMETHYL 2 5,8 DIHYDRONAPHTHYL)VINYL]BENZOIC ACID; 4 [2 (5,6,7,8 TETRAHYDRO 5,5,8,8 TETRAMETHYL 2 NAPHTHYL) 1,3 DIOXOLAN 2 YL]BENZOIC ACID; 4 [HYDROXYIMINO(3,5,5,8,8 PENTAMETHYL 5,6,7,8 TETRAHYDRO 2 NAPHTHYL)]BENZOIC ACID; 4 [HYDROXYIMINO[3,5,5,8,8 PENTAMETHYL(2 5,8 DIHYDRONAPHTHYL)]METHYL]BENZOIC ACID; 6 [(3,5,5,8,8 PENTAMETHYL 2 5,8 DIHYDRONAPHTHYL)CYCLOPROPYL]PYRIDINE 3 CARBOXYLIC ACID; 6 [1 (3,5,5,8,8 PENTAMETHYL 5,6,7,8 TETRAHYDRONAPHTHALEN 2 YL)CYCLOPROPYL]NICOTINIC ACID; BEXAROTENE; HORMONE RECEPTOR STIMULATING AGENT; RETINOID; RETINOID X RECEPTOR; UNCLASSIFIED DRUG;

ALKYLATION; ARTICLE; CATALYSIS; CHEMICAL REACTION; DRUG POTENCY; DRUG SYNTHESIS; NON INSULIN DEPENDENT DIABETES MELLITUS;

RECEPTORS, RETINOIC ACID; RETINOID X RECEPTORS; RETINOIDS; TETRAHYDRONAPHTHALENES; TRANSCRIPTION FACTORS;

EID: 0035943298     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo0103064     Document Type: Article

References (45)