메뉴 건너뛰기




Volumn 81, Issue 9, 2009, Pages 3645-3653

Simplifying fragmentation patterns of multiply charged peptides by N-terminal derivatization and electron transfer collision activated dissociation

Author keywords

[No Author keywords available]

Indexed keywords

COLLISION INDUCED DISSOCIATION; COLLISION-ACTIVATED DISSOCIATIONS; COLLISIONAL ACTIVATION; DE NOVO SEQUENCING; DERIVATIZATION; ELECTRON TRANSFER; ELECTRON-TRANSFER REACTIONS; FLUORANTHENE; FRAGMENTATION PATTERNS; LC-ESI-MS; LC-MS N; MODEL PEPTIDES; N-TERMINAL; RADICAL SPECIES; SIMPLIFICATION METHOD; TANDEM MASS SPECTROMETRY; TERMINAL RESIDUES; TRYPTIC DIGESTS;

EID: 66149143552     PISSN: 00032700     EISSN: None     Source Type: Journal    
DOI: 10.1021/ac9000942     Document Type: Article
Times cited : (42)

References (52)
  • 1
    • 52949094993 scopus 로고    scopus 로고
    • Service, R. F. Science 2008, 321, 1758-1761.
    • (2008) Science , vol.321 , pp. 1758-1761
    • Service, R.F.1
  • 51
    • 66149150025 scopus 로고    scopus 로고
    • When KRpTIRR was guanidinated before N-terminal derivatization, the already extremely basic peptide became even more basic with the conversion of the lysine to a homoarginine residue. This significantly reduced the abundance of the doubly charged ion, making it difficult to analyze; therefore, KRpTIRR was not guanidinated to ensure comparison of the ETcaD method with CID. This was the only lysine-containing peptide not guanidinated in this study
    • When KRpTIRR was guanidinated before N-terminal derivatization, the already extremely basic peptide became even more basic with the conversion of the lysine to a homoarginine residue. This significantly reduced the abundance of the doubly charged ion, making it difficult to analyze; therefore, KRpTIRR was not guanidinated to ensure comparison of the ETcaD method with CID. This was the only lysine-containing peptide not guanidinated in this study.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.