Observation of an unusually facile fragmentation pathway of gas-phase peptide ions: A study on the gas-phase fragmentation mechanism and energetics of tryptic peptides modified with 4-sulfophenyl isothiocyanate (SPITC) and 4-chlorosulfophenyl isocyanate (SPC) and their 18-crown-6 complexes

Journal of Mass Spectrometry

Volumn 42, Issue 3, 2007, Pages 380-388

  Shin, Joong Won ^a   Yong, Ho Lee ^a,d   Hwang, Sungu ^c   Lee, Sang Won ^b  

^a Seoul National University   (South Korea)

^b Korea University   (South Korea)

^c Pusan National University   (South Korea)

^d LG Chemical Ltd   (South Korea)

Author keywords

Collision induced dissociation; Density functional calculations; Electrospray ionization; Gas phase peptide fragmentation; Mass spectrometry

Indexed keywords

COLLISION-INDUCED DISSOCIATION; GAS-PHASE PEPTIDE FRAGMENTATION; QUANTUM MECHANICAL CALCULATIONS;

CHEMICAL MODIFICATION; CYANIDES; DENSITY FUNCTIONAL THEORY; DISSOCIATION; ELECTROSPRAY IONIZATION; NITROGEN; SULFONATION;

PEPTIDES;

4 CHLOROSULFOPHENYLISOCYANATE; 4 SULFOPHENYL ISOTHIOCYANATE; CROWN ETHER; CYANIC ACID DERIVATIVE; ISOTHIOCYANIC ACID; LYSINE; PEPTIDE DERIVATIVE; PEPTIDE FRAGMENT; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; CALCULATION; CARBOXY TERMINAL SEQUENCE; COLLISIONALLY ACTIVATED DISSOCIATION; ENERGY TRANSFER; GAS; INTERMETHOD COMPARISON; MASS SPECTROMETRY; PRIORITY JOURNAL; PROTEIN MODIFICATION; PROTEIN STRUCTURE; PROTON TRANSPORT; QUANTUM MECHANICS; SULFONATION;

BENZENESULFONATES; COMPUTER SIMULATION; CROWN ETHERS; GASES; IONS; ISOCYANATES; ISOTHIOCYANATES; MODELS, CHEMICAL; MODELS, MOLECULAR; PEPTIDE MAPPING; PEPTIDES; PHASE TRANSITION; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TRYPTOPHAN;

EID: 33947242915     PISSN: 10765174     EISSN: 10969888     Source Type: Journal    
DOI: 10.1002/jms.1172     Document Type: Article

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