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Volumn 39, Issue 3, 2009, Pages 205-217

Characterization of increased drug metabolism activity in dimethyl sulfoxide (DMSO)-treated Huh7 hepatoma cells

Author keywords

Differentiation; Dimethyl sulfoxide (DMSO); Drug metabolism; Huh7 cells

Indexed keywords

3 METHYLCHOLANTHRENE; ALBUMIN; AROMATIC HYDROCARBON RECEPTOR; BUFURALOL; CONSTITUTIVE ANDROSTANE RECEPTOR; CYTOCHROME P450 1A1; CYTOCHROME P450 1A2; CYTOCHROME P450 2B6; CYTOCHROME P450 2C19; CYTOCHROME P450 2C8; CYTOCHROME P450 2C9; CYTOCHROME P450 2D6; CYTOCHROME P450 3A4; CYTOCHROME P450 3A5; DEXTROMETHORPHAN; DICLOFENAC; DIMETHYL SULFOXIDE; GLUCURONOSYLTRANSFERASE 1A1; GLUCURONOSYLTRANSFERASE 1A4; GLUCURONOSYLTRANSFERASE 1A6; GLUCURONOSYLTRANSFERASE 1A9; GLUCURONOSYLTRANSFERASE 2B7; LAMOTRIGINE; MEPHENYTOIN; MESSENGER RNA; MIDAZOLAM; MORPHINE; PREALBUMIN; PREGNANE X RECEPTOR; RETINOID X RECEPTOR ALPHA; PRIMER DNA;

EID: 66149122259     PISSN: 00498254     EISSN: 13665928     Source Type: Journal    
DOI: 10.1080/00498250802613620     Document Type: Article
Times cited : (84)

References (46)
  • 3
    • 0042858402 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor alpha induces hepatic expression of the human bile acid glucuronidating UDP-glucuronosyltransferase 2B4 enzyme
    • Barbier O, Duran-Sandoval D, Pineda-Torra I, Kosykh V, Fruchart JC, Staels B. 2003. Peroxisome proliferator-activated receptor alpha induces hepatic expression of the human bile acid glucuronidating UDP-glucuronosyltransferase 2B4 enzyme. J Biol Chem 278:32852-32860.
    • (2003) J Biol Chem , vol.278 , pp. 32852-32860
    • Barbier, O.1    Duran-Sandoval, D.2    Pineda-Torra, I.3    Kosykh, V.4    Fruchart, J.C.5    Staels, B.6
  • 4
    • 0033927671 scopus 로고    scopus 로고
    • Measurement of cytochrome P450 gene induction in human hepatocytes using quantitative real-time reverse transcriptase-polymerase chain reaction
    • Bowen WP, Carey JE, Miah A, McMurray HF, Munday PW, James RS, Coleman RA, Brown AM. 2000. Measurement of cytochrome P450 gene induction in human hepatocytes using quantitative real-time reverse transcriptase-polymerase chain reaction. Drug Metab Dispos 28:781-788.
    • (2000) Drug Metab Dispos , vol.28 , pp. 781-788
    • Bowen, W.P.1    Carey, J.E.2    Miah, A.3    McMurray, H.F.4    Munday, P.W.5    James, R.S.6    Coleman, R.A.7    Brown, A.M.8
  • 5
    • 0030875708 scopus 로고    scopus 로고
    • The use of cultured hepatocytes to investigate the mechanisms of drug hepatotoxicity
    • Castell JV, Gomez-Lechon MJ, Ponsoda X, Bort R. 1997. The use of cultured hepatocytes to investigate the mechanisms of drug hepatotoxicity. Cell Biol Toxicol 13:331-338.
    • (1997) Cell Biol Toxicol , vol.13 , pp. 331-338
    • Castell, J.V.1    Gomez-Lechon, M.J.2    Ponsoda, X.3    Bort, R.4
  • 6
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
    • Chomczynski P, Sacchi N. 1987. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162:156-159.
    • (1987) Anal Biochem , vol.162 , pp. 156-159
    • Chomczynski, P.1    Sacchi, N.2
  • 8
    • 33745835398 scopus 로고    scopus 로고
    • Transmembrane transport of endo- and xenobiotics by mammalian ATP-binding cassette multidrug resistance proteins
    • Deeley RG, Westlake C, Cole SP. 2006. Transmembrane transport of endo- and xenobiotics by mammalian ATP-binding cassette multidrug resistance proteins. Physiol Rev 86:849-899.
    • (2006) Physiol Rev , vol.86 , pp. 849-899
    • Deeley, R.G.1    Westlake, C.2    Cole, S.P.3
  • 9
    • 0029033092 scopus 로고
    • Effect of model inducers on cytochrome P450 activities of human hepatocytes in primary culture
    • Donato MT, Castell JV, Gomez-Lechon MJ. 1995. Effect of model inducers on cytochrome P450 activities of human hepatocytes in primary culture. Drug Metab Dispos 23:553-558.
    • (1995) Drug Metab Dispos , vol.23 , pp. 553-558
    • Donato, M.T.1    Castell, J.V.2    Gomez-Lechon, M.J.3
  • 10
    • 34250665025 scopus 로고    scopus 로고
    • Cell culture systems for the hepatitis C virus
    • Duverlie G, Wychowski C. 2007. Cell culture systems for the hepatitis C virus. World J Gastroenterol 13:2442-2445.
    • (2007) World J Gastroenterol , vol.13 , pp. 2442-2445
    • Duverlie, G.1    Wychowski, C.2
  • 13
    • 34247510665 scopus 로고    scopus 로고
    • Hepatocytes - The choice to investigate drug metabolism and toxicity in man: In vitro variability as a reflection of in vivo
    • Gomez-Lechon MJ, Castell JV, Donato MT. 2007. Hepatocytes - the choice to investigate drug metabolism and toxicity in man: in vitro variability as a reflection of in vivo. Chem Biol Interact 168:30-50.
    • (2007) Chem Biol Interact , vol.168 , pp. 30-50
    • Gomez-Lechon, M.J.1    Castell, J.V.2    Donato, M.T.3
  • 14
    • 4644341747 scopus 로고    scopus 로고
    • Human hepatocytes in primary culture: The choice to investigate drug metabolism in man
    • Gomez-Lechon MJ, Donato MT, Castell JV, Jover R. 2004. Human hepatocytes in primary culture: The choice to investigate drug metabolism in man. Curr Drug Metab 5:443-462.
    • (2004) Curr Drug Metab , vol.5 , pp. 443-462
    • Gomez-Lechon, M.J.1    Donato, M.T.2    Castell, J.V.3    Jover, R.4
  • 16
    • 34247517355 scopus 로고    scopus 로고
    • The human hepatoma HepaRG cells: A highly differentiated model for studies of liver metabolism and toxicity of xenobiotics
    • Guillouzo A, Corlu A, Aninat C, Glaise D, Morel F, Guguen-Guillouzo C. 2007. The human hepatoma HepaRG cells: a highly differentiated model for studies of liver metabolism and toxicity of xenobiotics. Chem Biol Interact 168:66-73.
    • (2007) Chem Biol Interact , vol.168 , pp. 66-73
    • Guillouzo, A.1    Corlu, A.2    Aninat, C.3    Glaise, D.4    Morel, F.5    Guguen-Guillouzo, C.6
  • 17
    • 0037341552 scopus 로고    scopus 로고
    • Metformin rapidly increases insulin receptor activation in human liver and signals preferentially through insulin-receptor substrate-2
    • Gunton JE, Delhanty PJ, Takahashi S, Baxter RC. 2003. Metformin rapidly increases insulin receptor activation in human liver and signals preferentially through insulin-receptor substrate-2. J Clin Endocrinol Metab 88:1323-1332.
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 1323-1332
    • Gunton, J.E.1    Delhanty, P.J.2    Takahashi, S.3    Baxter, R.C.4
  • 19
    • 28144442034 scopus 로고    scopus 로고
    • Prediction of metabolic clearance using cryopreserved human hepatocytes: Kinetic characteristics for five benzodiazepines
    • Hallifax D, Rawden HC, Hakooz N, Houston JB. 2005. Prediction of metabolic clearance using cryopreserved human hepatocytes: kinetic characteristics for five benzodiazepines. Drug Metab Dispos 33:1852-1858.
    • (2005) Drug Metab Dispos , vol.33 , pp. 1852-1858
    • Hallifax, D.1    Rawden, H.C.2    Hakooz, N.3    Houston, J.B.4
  • 20
    • 33745713380 scopus 로고    scopus 로고
    • A prospective study of isolated human hepatocyte function following liver resection for colorectal liver metastases: The effects of prior exposure to chemotherapy
    • Hewes JC, Riddy D, Morris RW, Woodrooffe AJ, Davidson BR, Fuller B. 2006. A prospective study of isolated human hepatocyte function following liver resection for colorectal liver metastases: The effects of prior exposure to chemotherapy. J Hepatol 45:263-270.
    • (2006) J Hepatol , vol.45 , pp. 263-270
    • Hewes, J.C.1    Riddy, D.2    Morris, R.W.3    Woodrooffe, A.J.4    Davidson, B.R.5    Fuller, B.6
  • 21
    • 1842627852 scopus 로고    scopus 로고
    • Phase i and II enzyme characterization of two sources of HepG2 cell lines
    • Hewitt NJ, Hewitt P. 2004. Phase I and II enzyme characterization of two sources of HepG2 cell lines. Xenobiotica 34:243-256.
    • (2004) Xenobiotica , vol.34 , pp. 243-256
    • Hewitt, N.J.1    Hewitt, P.2
  • 22
    • 36749054104 scopus 로고    scopus 로고
    • Inhibition of hepatitis C virus replication by peroxidation of arachidonate and restoration by vitamin e
    • Huang H, Chen Y, Ye J. 2007. Inhibition of hepatitis C virus replication by peroxidation of arachidonate and restoration by vitamin E. Proc Natl Acad Sci USA 104:18666-18670.
    • (2007) Proc Natl Acad Sci USA 104 , pp. 18666-18670
    • Huang, H.1    Chen, Y.2    Ye, J.3
  • 23
    • 46449089949 scopus 로고    scopus 로고
    • Evaluation of HepaRG cells as an in vitro model for human drug metabolism studies
    • Kanebratt KP, Andersson TB. 2008. Evaluation of HepaRG cells as an in vitro model for human drug metabolism studies. Drug Metab Dispos 36:1444-1452.
    • (2008) Drug Metab Dispos , vol.36 , pp. 1444-1452
    • Kanebratt, K.P.1    Andersson, T.B.2
  • 24
    • 1642375906 scopus 로고    scopus 로고
    • The efficacy of the combination therapy of 5-fluorouracil, cisplatin and leucovorin for hepatocellular carcinoma and its predictable factors
    • Kogure T, Ueno Y, Iwasaki T, Shimosegawa T. 2004. The efficacy of the combination therapy of 5-fluorouracil, cisplatin and leucovorin for hepatocellular carcinoma and its predictable factors. Cancer Chemother Pharmacol 53:296-304.
    • (2004) Cancer Chemother Pharmacol , vol.53 , pp. 296-304
    • Kogure, T.1    Ueno, Y.2    Iwasaki, T.3    Shimosegawa, T.4
  • 25
    • 0033670712 scopus 로고    scopus 로고
    • Effects of macrolide antibiotics on CYP3A expression in human and rat hepatocytes: Interspecies differences in response to troleandomycin
    • Ledirac N, de Sousa G, Fontaine F, Agouridas C, Gugenheim J, Lorenzon G, Rahmani R. 2000. Effects of macrolide antibiotics on CYP3A expression in human and rat hepatocytes: interspecies differences in response to troleandomycin. Drug Metab Dispos 28:1391-1393.
    • (2000) Drug Metab Dispos , vol.28 , pp. 1391-1393
    • Ledirac, N.1    De Sousa, G.2    Fontaine, F.3    Agouridas, C.4    Gugenheim, J.5    Lorenzon, G.6    Rahmani, R.7
  • 26
    • 0030665109 scopus 로고    scopus 로고
    • Primary human hepatocytes as a tool for the evaluation of structure-activity relationship in cytochrome P450 induction potential of xenobiotics: Evaluation of rifampin, rifapentine and rifabutin
    • Li AP, Reith MK, Rasmussen A, Gorski JC, Hall SD, Xu L, Kaminski DL, Cheng LK. 1997. Primary human hepatocytes as a tool for the evaluation of structure-activity relationship in cytochrome P450 induction potential of xenobiotics: evaluation of rifampin, rifapentine and rifabutin. Chem Biol Interact 107:17-30.
    • (1997) Chem Biol Interact , vol.107 , pp. 17-30
    • Li, A.P.1    Reith, M.K.2    Rasmussen, A.3    Gorski, J.C.4    Hall, S.D.5    Xu, L.6    Kaminski, D.L.7    Cheng, L.K.8
  • 27
    • 34250708477 scopus 로고    scopus 로고
    • CYP1A induction and human risk assessment: An evolving tale of in vitro and in vivo studies
    • Ma Q, Lu AY. 2007. CYP1A induction and human risk assessment: an evolving tale of in vitro and in vivo studies. Drug Metab Dispos 35:1009-1016.
    • (2007) Drug Metab Dispos , vol.35 , pp. 1009-1016
    • Ma, Q.1    Lu, A.Y.2
  • 28
    • 0032841888 scopus 로고    scopus 로고
    • The role of CYP2C19 in the metabolism of (+/-) bufuralol, the prototypic substrate of CYP2D6
    • Mankowski DC. 1999. The role of CYP2C19 in the metabolism of (+/-) bufuralol, the prototypic substrate of CYP2D6. Drug Metab Dispos 27:1024-1028.
    • (1999) Drug Metab Dispos , vol.27 , pp. 1024-1028
    • Mankowski, D.C.1
  • 29
    • 33845473315 scopus 로고    scopus 로고
    • Species differences between mouse, rat, dog, monkey and human CYP-mediated drug metabolism, inhibition and induction
    • Martignoni M, Groothuis GM, de Kanter R. 2006. Species differences between mouse, rat, dog, monkey and human CYP-mediated drug metabolism, inhibition and induction. Expert Opin Drug Metab Toxicol 2:875-894.
    • (2006) Expert Opin Drug Metab Toxicol , vol.2 , pp. 875-894
    • Martignoni, M.1    Groothuis, G.M.2    De Kanter, R.3
  • 30
    • 0035119064 scopus 로고    scopus 로고
    • Regulation of cytochrome p450 by inflammatory mediators: Why and how?
    • Morgan ET. 2001. Regulation of cytochrome p450 by inflammatory mediators: why and how? Drug Metab Dispos 29:207-212.
    • (2001) Drug Metab Dispos , vol.29 , pp. 207-212
    • Morgan, E.T.1
  • 31
    • 0019966544 scopus 로고
    • Growth of human hepatoma cells lines with differentiated functions in chemically defined medium
    • Nakabayashi H, Taketa K, Miyano K, Yamane T, Sato J. 1982. Growth of human hepatoma cells lines with differentiated functions in chemically defined medium. Cancer Res 42:3858-3863.
    • (1982) Cancer Res , vol.42 , pp. 3858-3863
    • Nakabayashi, H.1    Taketa, K.2    Miyano, K.3    Yamane, T.4    Sato, J.5
  • 32
    • 34250699025 scopus 로고    scopus 로고
    • Gene expression profiling and differentiation assessment in primary human hepatocyte cultures, established hepatoma cell lines, and human liver tissues
    • Olsavsky KM, Page JL, Johnson MC, Zarbl H, Strom SC, Omiecinski CJ. 2007. Gene expression profiling and differentiation assessment in primary human hepatocyte cultures, established hepatoma cell lines, and human liver tissues. Toxicol Appl Pharmacol 222:42-56.
    • (2007) Toxicol Appl Pharmacol , vol.222 , pp. 42-56
    • Olsavsky, K.M.1    Page, J.L.2    Johnson, M.C.3    Zarbl, H.4    Strom, S.C.5    Omiecinski, C.J.6
  • 34
    • 13444292820 scopus 로고    scopus 로고
    • Impact of transcription factor profile and chromatin conformation on human hepatocyte CYP3A gene expression
    • Phillips A, Hood SR, Gibson GG, Plant NJ. 2005. Impact of transcription factor profile and chromatin conformation on human hepatocyte CYP3A gene expression. Drug Metab Dispos 33:233-242.
    • (2005) Drug Metab Dispos , vol.33 , pp. 233-242
    • Phillips, A.1    Hood, S.R.2    Gibson, G.G.3    Plant, N.J.4
  • 35
    • 15444378115 scopus 로고    scopus 로고
    • A historical overview of the heterologous expression of mammalian UDPglucuronosyltransferase isoforms over the past twenty years
    • Radominska-Pandya A, Bratton S, Little JM. 2005. A historical overview of the heterologous expression of mammalian UDPglucuronosyltransferase isoforms over the past twenty years. Curr Drug Metab 6:141-160.
    • (2005) Curr Drug Metab , vol.6 , pp. 141-160
    • Radominska-Pandya, A.1    Bratton, S.2    Little, J.M.3
  • 37
    • 33749465247 scopus 로고    scopus 로고
    • Production of infectious hepatitis C virus by well-differentiated, growth-arrested human hepatoma- derived cells
    • Sainz B, Jr, Chisari FV. 2006. Production of infectious hepatitis C virus by well-differentiated, growth-arrested human hepatoma- derived cells. J Virol 80:10253-10257.
    • (2006) J Virol , vol.80 , pp. 10253-10257
    • Sainz, B.1    Chisari Jr., F.V.2
  • 38
    • 44349182094 scopus 로고    scopus 로고
    • Post-transcriptional regulation of human pregnane X receptor by micro-RNA affects the expression of cytochrome P450 3A4
    • Takagi S, Nakajima M, Mohri T, Yokoi T. 2008. Post-transcriptional regulation of human pregnane X receptor by micro-RNA affects the expression of cytochrome P450 3A4. J Biol Chem 283:9674-9680.
    • (2008) J Biol Chem , vol.283 , pp. 9674-9680
    • Takagi, S.1    Nakajima, M.2    Mohri, T.3    Yokoi, T.4
  • 40
    • 35648987166 scopus 로고    scopus 로고
    • Mechanism-based inactivation of human cytochrome P450 enzymes: Strategies for diagnosis and drug-drug interaction risk assessment
    • DOI 10.1080/00498250701670945, PII 783596346, Modelling and Simulation Approaches to in vitro-in vivo, Extrapolation of ADME Properties in Drug Development, Editor: Gordon Gibson, Guest Editor: Amin Rostami-Hodjegan
    • Venkatakrishnan K, Obach RS, Rostami-Hodjegan A. 2007. Mechanism-based inactivation of human cytochrome P450 enzymes: strategies for diagnosis and drug-drug interaction risk assessment. Xenobiotica 37:1225-1256. (Pubitemid 350035532)
    • (2007) Xenobiotica , vol.37 , Issue.10-11 , pp. 1225-1256
    • Venkatakrishnan, K.1    Obach, R.S.2    Rostami-Hodjegan, A.3
  • 44
    • 0034782996 scopus 로고    scopus 로고
    • Comparative contribution to dextromethorphan metabolism by cytochrome P450 isoforms in vitro: Can dextromethorphan be used as a dual probe for both CTP2D6 and CYP3A activities?
    • Yu A, Haining RL. 2001. Comparative contribution to dextromethorphan metabolism by cytochrome P450 isoforms in vitro: can dextromethorphan be used as a dual probe for both CTP2D6 and CYP3A activities? Drug Metab Dispos 29:1514-1520.
    • (2001) Drug Metab Dispos , vol.29 , pp. 1514-1520
    • Yu, A.1    Haining, R.L.2
  • 45
    • 0036893593 scopus 로고    scopus 로고
    • Evaluation of cytochrome P450 probe substrates commonly used by the pharmaceutical industry to study in vitro drug interactions
    • Yuan R, Madani S, Wei XX, Reynolds K, Huang SM. 2002. Evaluation of cytochrome P450 probe substrates commonly used by the pharmaceutical industry to study in vitro drug interactions. Drug Metab Dispos 30:1311-1319.
    • (2002) Drug Metab Dispos , vol.30 , pp. 1311-1319
    • Yuan, R.1    Madani, S.2    Wei, X.X.3    Reynolds, K.4    Huang, S.M.5


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