메뉴 건너뛰기




Volumn 6, Issue 4, 2008, Pages 379-385

Neuropharmacological mechanisms underlying the neuroprotective effects of methylphenidate

Author keywords

Dopamine; Dopamine transporter; Methamphetamine; Methylphenidate; Neuroprotection; Neurotoxicity; Parkinson's disease; Vesicular monoamine transporter 2

Indexed keywords

1 METHYL 4 PHENYLPYRIDINIUM; AMFEBUTAMONE; AMFONELIC ACID; AMPHETAMINE; BENZATROPINE; COCAINE DERIVATIVE; DOPAMINE; DOPAMINE 2 RECEPTOR; DOPAMINE TRANSPORTER; ETICLOPRIDE; LOBELINE; MAZINDOL; METHAMPHETAMINE; METHYLPHENIDATE; QUINPIROLE; REACTIVE OXYGEN METABOLITE; RESERPINE; VESICULAR MONOAMINE TRANSPORTER 2;

EID: 66149114444     PISSN: 1570159X     EISSN: None     Source Type: Journal    
DOI: 10.2174/157015908787386041     Document Type: Review
Times cited : (31)

References (78)
  • 1
    • 0026562727 scopus 로고
    • Affinity of different local anesthetic drugs and catecholamines for the contraluminal transport system for organic cations in proximal tubules of rat kidneys
    • Brandle, E., Fritzsch, G., Greven, J. (1992) Affinity of different local anesthetic drugs and catecholamines for the contraluminal transport system for organic cations in proximal tubules of rat kidneys. J. Pharmacol. Exp. Ther., 260, 734-741.
    • (1992) J. Pharmacol. Exp. Ther , vol.260 , pp. 734-741
    • Brandle, E.1    Fritzsch, G.2    Greven, J.3
  • 2
    • 0034048662 scopus 로고    scopus 로고
    • Methamphetamine rapidly decreases vesicular dopamine uptake
    • Brown, J.M., Hanson, G.R., Fleckenstein, A.E. (2000) Methamphetamine rapidly decreases vesicular dopamine uptake. J. Neurochem., 74, 2221-2223.
    • (2000) J. Neurochem , vol.74 , pp. 2221-2223
    • Brown, J.M.1    Hanson, G.R.2    Fleckenstein, A.E.3
  • 3
    • 0038201683 scopus 로고    scopus 로고
    • Effects of amphetamines on mitochondrial function: Role of free radicals and oxidative stress
    • Brown, J.M., Yamamoto, B.K. (2003) Effects of amphetamines on mitochondrial function: role of free radicals and oxidative stress. Pharmacol. Ther., 99, 45-53.
    • (2003) Pharmacol. Ther , vol.99 , pp. 45-53
    • Brown, J.M.1    Yamamoto, B.K.2
  • 4
    • 0036848458 scopus 로고    scopus 로고
    • Atomoxetine increases extracellular levels of norepinephrine and dopamine in prefrontal cortex of rat: A potential mechanism for efficacy in attention deficit/hyperactivity disorder
    • Bymaster, F.P., Katner, J.S., Nelson, D.L., Hemrick-Luecke, S.K., Threlkeld, P.G., Heiligenstein, J.H., Morin, S.M., Gehlert, D.R., Perry, K.W. (2002) Atomoxetine increases extracellular levels of norepinephrine and dopamine in prefrontal cortex of rat: a potential mechanism for efficacy in attention deficit/hyperactivity disorder. Neuropsychopharmacology, 27, 699-711.
    • (2002) Neuropsychopharmacology , vol.27 , pp. 699-711
    • Bymaster, F.P.1    Katner, J.S.2    Nelson, D.L.3    Hemrick-Luecke, S.K.4    Threlkeld, P.G.5    Heiligenstein, J.H.6    Morin, S.M.7    Gehlert, D.R.8    Perry, K.W.9
  • 5
    • 0031200869 scopus 로고    scopus 로고
    • Free radicals and the pathobiology of brain dopamine systems
    • Cadet, J.L., Brannock, C. (1998) Free radicals and the pathobiology of brain dopamine systems. Neurochem. Int., 32, 117-131.
    • (1998) Neurochem. Int , vol.32 , pp. 117-131
    • Cadet, J.L.1    Brannock, C.2
  • 6
    • 0026566383 scopus 로고
    • Cocaine receptor: Biochemical characterization and structure-activity relationships of cocaine analogues at the dopamine transporter
    • Carroll, F.I., Lewin, A.H., Boja, J.W., Kuhar, M.J. (1992) Cocaine receptor: biochemical characterization and structure-activity relationships of cocaine analogues at the dopamine transporter. J. Med. Chem., 35, 969-981.
    • (1992) J. Med. Chem , vol.35 , pp. 969-981
    • Carroll, F.I.1    Lewin, A.H.2    Boja, J.W.3    Kuhar, M.J.4
  • 7
    • 0033948078 scopus 로고    scopus 로고
    • Methylphenidate: Its pharmacology and uses
    • Challman, T.D., Lipsky, J.J. (2000) Methylphenidate: its pharmacology and uses. Mayo Clin. Proc., 75, 711-721.
    • (2000) Mayo Clin. Proc , vol.75 , pp. 711-721
    • Challman, T.D.1    Lipsky, J.J.2
  • 8
    • 0028329215 scopus 로고
    • Methamphetamine neurotoxicity involves vacuolation of endocytic organelles and dopamine-dependent intracellular oxidative stress
    • Cubells, J.F., Rayport, S., Rajendran, G., Sulzer, D. (1994) Methamphetamine neurotoxicity involves vacuolation of endocytic organelles and dopamine-dependent intracellular oxidative stress. J. Neurosci., 14, 2260-2271.
    • (1994) J. Neurosci , vol.14 , pp. 2260-2271
    • Cubells, J.F.1    Rayport, S.2    Rajendran, G.3    Sulzer, D.4
  • 10
    • 11844260723 scopus 로고    scopus 로고
    • Lobeline attenuates methamphetamine-induced changes in vesicular monoamine transporter-2 immunoreactivity and monoamine depletions in the striatum
    • Eyerman, D.J., Yamamoto, B.K. (2005) Lobeline attenuates methamphetamine-induced changes in vesicular monoamine transporter-2 immunoreactivity and monoamine depletions in the striatum. J. Pharmacol. Exp. Ther., 312, 160-169.
    • (2005) J. Pharmacol. Exp. Ther , vol.312 , pp. 160-169
    • Eyerman, D.J.1    Yamamoto, B.K.2
  • 11
    • 0022679275 scopus 로고
    • Methylphenidate treatment of patients with head and neck cancer
    • Fernandez, F., Adams, F. (1986) Methylphenidate treatment of patients with head and neck cancer. Head Neck Surg., 8, 296-300.
    • (1986) Head Neck Surg , vol.8 , pp. 296-300
    • Fernandez, F.1    Adams, F.2
  • 14
    • 9644289489 scopus 로고    scopus 로고
    • An intermittent, controlled-rate, slow progressive degeneration model of Parkinson's disease: Antiparkinson effects of Sinemet and protective effects of methylphenidate
    • Fleming, S.M., Delville, Y., Schallert, T. (2005) An intermittent, controlled-rate, slow progressive degeneration model of Parkinson's disease: antiparkinson effects of Sinemet and protective effects of methylphenidate. Behav. Brain Res., 156, 201-213.
    • (2005) Behav. Brain Res , vol.156 , pp. 201-213
    • Fleming, S.M.1    Delville, Y.2    Schallert, T.3
  • 15
    • 0028790530 scopus 로고
    • Conformational analysis of methylphenidate and its structural relationship to other dopamine reuptake blockers such as CFT
    • Froimowitz, M., Patrick, K.S., Cody, V. (1995) Conformational analysis of methylphenidate and its structural relationship to other dopamine reuptake blockers such as CFT. Pharm. Res., 12, 1430-1434.
    • (1995) Pharm. Res , vol.12 , pp. 1430-1434
    • Froimowitz, M.1    Patrick, K.S.2    Cody, V.3
  • 16
    • 0032125186 scopus 로고    scopus 로고
    • Role of dopamine transporter in methamphetamine-induced neurotoxicity: Evidence from mice lacking the transporter
    • Fumagalli, F., Gainetdinov, R.R., Valenzano, K.J., Caron, M.G. (1998) Role of dopamine transporter in methamphetamine-induced neurotoxicity: evidence from mice lacking the transporter. J. Neurosci., 18, 4861-4869.
    • (1998) J. Neurosci , vol.18 , pp. 4861-4869
    • Fumagalli, F.1    Gainetdinov, R.R.2    Valenzano, K.J.3    Caron, M.G.4
  • 17
    • 0033118563 scopus 로고    scopus 로고
    • Increased methamphetamine neurotoxicity in heterozygous vesicular monoamine transporter 2 knock-out mice
    • Fumagalli, F., Gainetdinov, R.R., Wang, Y.M., Valenzano, K.J., Miller, G.W., Caron, M.G. (1999) Increased methamphetamine neurotoxicity in heterozygous vesicular monoamine transporter 2 knock-out mice. J. Neurosci., 19, 2424-2431.
    • (1999) J. Neurosci , vol.19 , pp. 2424-2431
    • Fumagalli, F.1    Gainetdinov, R.R.2    Wang, Y.M.3    Valenzano, K.J.4    Miller, G.W.5    Caron, M.G.6
  • 18
    • 0026561857 scopus 로고
    • Pharmacologic treatment of attention deficit hyperactivity disorder
    • Greenhill, L.L. (1992) Pharmacologic treatment of attention deficit hyperactivity disorder. Psychiatr. Clin. North Am., 15, 1-27.
    • (1992) Psychiatr. Clin. North Am , vol.15 , pp. 1-27
    • Greenhill, L.L.1
  • 19
    • 33846486983 scopus 로고    scopus 로고
    • Evaluation of the lipophilic properties of opioids, amphetamine-like drugs, and metabolites through electrochemical studies at the interface between two immiscible solutions
    • Gulaboski, R., Cordeiro, M.N., Milhazes, N., Garrido, J., Borges, F., Jorge, M., Pereira, C.M., Bogeski, I., Morales, A.H., Naumoski, B., Silva, A.F. (2007) Evaluation of the lipophilic properties of opioids, amphetamine-like drugs, and metabolites through electrochemical studies at the interface between two immiscible solutions. Anal. Biochem., 361, 236-243.
    • (2007) Anal. Biochem , vol.361 , pp. 236-243
    • Gulaboski, R.1    Cordeiro, M.N.2    Milhazes, N.3    Garrido, J.4    Borges, F.5    Jorge, M.6    Pereira, C.M.7    Bogeski, I.8    Morales, A.H.9    Naumoski, B.10    Silva, A.F.11
  • 20
    • 0027945880 scopus 로고
    • Evidence that pure uptake inhibitors including cocaine interact slowly with the dopamine neuronal carrier
    • Heron, C., Costentin, J., Bonnet, J.J. (1994) Evidence that pure uptake inhibitors including cocaine interact slowly with the dopamine neuronal carrier. Eur. J. Pharmacol., 264, 391-398.
    • (1994) Eur. J. Pharmacol , vol.264 , pp. 391-398
    • Heron, C.1    Costentin, J.2    Bonnet, J.J.3
  • 21
    • 0034007741 scopus 로고    scopus 로고
    • Analysis of VMAT2 binding after methamphetamine or MPTP treatment: Disparity between homogenates and vesicle preparations
    • Hogan, K.A., Staal, R.G., Sonsalla, P.K. (2000) Analysis of VMAT2 binding after methamphetamine or MPTP treatment: disparity between homogenates and vesicle preparations. J. Neurochem., 74, 2217-2220.
    • (2000) J. Neurochem , vol.74 , pp. 2217-2220
    • Hogan, K.A.1    Staal, R.G.2    Sonsalla, P.K.3
  • 22
    • 0031899172 scopus 로고    scopus 로고
    • Oxidative mechanisms in nigral cell death in Parkinson's disease
    • Jenner, P. (1998) Oxidative mechanisms in nigral cell death in Parkinson's disease. Mov. Disord., 13, 24-34.
    • (1998) Mov. Disord , vol.13 , pp. 24-34
    • Jenner, P.1
  • 24
    • 0032521354 scopus 로고    scopus 로고
    • Mechanisms of amphetamine action revealed in mice lacking the dopamine transporter
    • Jones, S.R., Gainetdinov, R.R., Wightman, R.M., Caron, M.G. (1998) Mechanisms of amphetamine action revealed in mice lacking the dopamine transporter. J. Neurosci., 18, 1979-1986.
    • (1998) J. Neurosci , vol.18 , pp. 1979-1986
    • Jones, S.R.1    Gainetdinov, R.R.2    Wightman, R.M.3    Caron, M.G.4
  • 26
    • 0030949516 scopus 로고    scopus 로고
    • Effects of methylphenidate on extracellular dopamine, serotonin, and norepinephrine: Comparison with amphetamine
    • Kuczenski, R., Segal, D.S. (1997) Effects of methylphenidate on extracellular dopamine, serotonin, and norepinephrine: comparison with amphetamine. J. Neurochem., 68, 2032-2037.
    • (1997) J. Neurochem , vol.68 , pp. 2032-2037
    • Kuczenski, R.1    Segal, D.S.2
  • 27
    • 0037109770 scopus 로고    scopus 로고
    • Methamphetamine-induced degeneration of dopaminergic neurons involves autophagy and upregulation of dopamine synthesis
    • Larsen, K.E., Fon, E.A., Hastings, T.G., Edwards, R.H., Sulzer, D. (2002) Methamphetamine-induced degeneration of dopaminergic neurons involves autophagy and upregulation of dopamine synthesis. J. Neurosci., 22, 8951-8960.
    • (2002) J. Neurosci , vol.22 , pp. 8951-8960
    • Larsen, K.E.1    Fon, E.A.2    Hastings, T.G.3    Edwards, R.H.4    Sulzer, D.5
  • 28
    • 0020004473 scopus 로고
    • Comparison of the release of [3H]dopamine from isolated corpus striatum by amphetamine, fenfluramine and unlabelled dopamine
    • Liang, N.Y., Rutledge, C.O. (1982) Comparison of the release of [3H]dopamine from isolated corpus striatum by amphetamine, fenfluramine and unlabelled dopamine. Biochem. Pharmacol., 31, 983-992.
    • (1982) Biochem. Pharmacol , vol.31 , pp. 983-992
    • Liang, N.Y.1    Rutledge, C.O.2
  • 29
    • 0038721600 scopus 로고    scopus 로고
    • Presynaptic control of quantal size: Kinetic mechanisms and implications for synaptic transmission and plasticity
    • Liu, G. (2003) Presynaptic control of quantal size: kinetic mechanisms and implications for synaptic transmission and plasticity. Curr. Opin. Neurobiol., 13, 324-331.
    • (2003) Curr. Opin. Neurobiol , vol.13 , pp. 324-331
    • Liu, G.1
  • 31
    • 0025363872 scopus 로고
    • Dopamine uptake inhibitors block long-term neurotoxic effects of methamphetamine upon dopaminergic neurons
    • Marek, G.J., Vosmer, G., Seiden, L.S. (1990) Dopamine uptake inhibitors block long-term neurotoxic effects of methamphetamine upon dopaminergic neurons. Brain Res., 513, 274-279.
    • (1990) Brain Res , vol.513 , pp. 274-279
    • Marek, G.J.1    Vosmer, G.2    Seiden, L.S.3
  • 33
    • 0034746913 scopus 로고    scopus 로고
    • Dopamine D2 receptor regulation of the dopamine transporter expressed in Xenopus laevis oocytes is voltage-independent
    • Mayfield, R.D., Zahniser, N.R. (2001) Dopamine D2 receptor regulation of the dopamine transporter expressed in Xenopus laevis oocytes is voltage-independent. Mol. Pharmacol., 59, 113-121.
    • (2001) Mol. Pharmacol , vol.59 , pp. 113-121
    • Mayfield, R.D.1    Zahniser, N.R.2
  • 34
    • 0027337280 scopus 로고
    • D2 receptors may modulate the function of the striatal transporter for dopamine: Kinetic evidence from studies in vitro and in vivo
    • Meiergerd, S.M., Patterson, T.A., Schenk, J.O. (1993) D2 receptors may modulate the function of the striatal transporter for dopamine: kinetic evidence from studies in vitro and in vivo. J. Neurochem., 61, 764-767.
    • (1993) J. Neurochem , vol.61 , pp. 764-767
    • Meiergerd, S.M.1    Patterson, T.A.2    Schenk, J.O.3
  • 35
    • 0028122506 scopus 로고
    • Narcolepsy and its treatment with stimulants. ASDA standards of practice
    • Mitler, M.M., Aldrich, M.S., Koob, G.F., Zarcone, V.P. (1994) Narcolepsy and its treatment with stimulants. ASDA standards of practice. Sleep, 17, 352-371.
    • (1994) Sleep , vol.17 , pp. 352-371
    • Mitler, M.M.1    Aldrich, M.S.2    Koob, G.F.3    Zarcone, V.P.4
  • 37
    • 29144493185 scopus 로고    scopus 로고
    • Immunoisolation of two synaptic vesicle pools from synaptosomes: A proteomics analysis
    • Morciano, M., Burre, J., Corvey, C., Karas, M., Zimmermann, H., Volknandt, W. (2005) Immunoisolation of two synaptic vesicle pools from synaptosomes: a proteomics analysis. J. Neurochem., 95, 1732-1745.
    • (2005) J. Neurochem , vol.95 , pp. 1732-1745
    • Morciano, M.1    Burre, J.2    Corvey, C.3    Karas, M.4    Zimmermann, H.5    Volknandt, W.6
  • 38
    • 0020557414 scopus 로고
    • Differential effects of d-amphetamine, beta-phenylethylamine, cocaine and methylphenidate on the rate of dopamine synthesis in terminals of nigrostriatal and mesolimbic neurons and on the efflux of dopamine metabolites into cerebroventricular perfusates of rats
    • Nielsen, J.A., Chapin, D.S., Moore, K.E. (1983) Differential effects of d-amphetamine, beta-phenylethylamine, cocaine and methylphenidate on the rate of dopamine synthesis in terminals of nigrostriatal and mesolimbic neurons and on the efflux of dopamine metabolites into cerebroventricular perfusates of rats. Life Sci., 33, 1899-1907.
    • (1983) Life Sci , vol.33 , pp. 1899-1907
    • Nielsen, J.A.1    Chapin, D.S.2    Moore, K.E.3
  • 39
    • 0030431704 scopus 로고    scopus 로고
    • Inhibition of dopamine synthesis by dopamine D2 and D3 but not D4 receptors
    • O'Hara, C.M., Uhland-Smith, A., O'Malley, K.L., Todd, R.D. (1996) Inhibition of dopamine synthesis by dopamine D2 and D3 but not D4 receptors. J. Pharmacol. Exp. Ther., 277, 186-192.
    • (1996) J. Pharmacol. Exp. Ther , vol.277 , pp. 186-192
    • O'Hara, C.M.1    Uhland-Smith, A.2    O'Malley, K.L.3    Todd, R.D.4
  • 40
    • 84946393460 scopus 로고
    • La preparazione di piridil- e piperidilarilacetonitrill e di alcuni productti di transformazione.
    • Panizzon, L. (1944) La preparazione di piridil- e piperidilarilacetonitrill e di alcuni productti di transformazione. Helv. Chim. Acta, 27, 1748-1756.
    • (1944) Helv. Chim. Acta , vol.27 , pp. 1748-1756
    • Panizzon, L.1
  • 42
    • 0035300236 scopus 로고    scopus 로고
    • Mobility and ionization constant of basic drugs in methanol. Applicaton of nonaqueous background electrolytes for capillary zone electrophoresis based on a conventional pH scale
    • Sep
    • Porras, S.P., Jyske, P., Riekkola, M., Kenndler, E. (2001) Mobility and ionization constant of basic drugs in methanol. Applicaton of nonaqueous background electrolytes for capillary zone electrophoresis based on a conventional pH scale. J. Microcolumn Sep., 13, 149-155.
    • (2001) J. Microcolumn , vol.13 , pp. 149-155
    • Porras, S.P.1    Jyske, P.2    Riekkola, M.3    Kenndler, E.4
  • 43
    • 0037008254 scopus 로고    scopus 로고
    • Differential trafficking of the vesicular monoamine transporter-2 by methamphetamine and cocaine
    • Riddle, E.L., Topham, M.K., Haycock, J.W., Hanson, G.R., Fleckenstein, A.E. (2002) Differential trafficking of the vesicular monoamine transporter-2 by methamphetamine and cocaine. Eur. J. Pharmacol., 449, 71-74.
    • (2002) Eur. J. Pharmacol , vol.449 , pp. 71-74
    • Riddle, E.L.1    Topham, M.K.2    Haycock, J.W.3    Hanson, G.R.4    Fleckenstein, A.E.5
  • 44
    • 1642296166 scopus 로고    scopus 로고
    • The structural organization of the readily releasable pool of synaptic vesicles
    • Rizzoli, S.O., Betz, W.J. (2004) The structural organization of the readily releasable pool of synaptic vesicles. Science, 303, 2037-2039.
    • (2004) Science , vol.303 , pp. 2037-2039
    • Rizzoli, S.O.1    Betz, W.J.2
  • 46
    • 0037369811 scopus 로고    scopus 로고
    • Methylphenidate alters vesicular monoamine transport and prevents methamphetamine-induced dopaminergic deficits
    • Sandoval, V., Riddle, E.L., Hanson, G.R., Fleckenstein, A.E. (2003) Methylphenidate alters vesicular monoamine transport and prevents methamphetamine-induced dopaminergic deficits. J. Pharmacol. Exp. Ther., 304, 1181-1187.
    • (2003) J. Pharmacol. Exp. Ther , vol.304 , pp. 1181-1187
    • Sandoval, V.1    Riddle, E.L.2    Hanson, G.R.3    Fleckenstein, A.E.4
  • 47
    • 0036812515 scopus 로고    scopus 로고
    • Methylphenidate redistributes vesicular monoamine transporter-2: Role of dopamine receptors
    • Sandoval, V., Riddle, E.L., Hanson, G.R., Fleckenstein, A.E. (2002) Methylphenidate redistributes vesicular monoamine transporter-2: Role of dopamine receptors. J. Neurosci., 22, 8705-8710.
    • (2002) J. Neurosci , vol.22 , pp. 8705-8710
    • Sandoval, V.1    Riddle, E.L.2    Hanson, G.R.3    Fleckenstein, A.E.4
  • 48
    • 0036389816 scopus 로고    scopus 로고
    • The functioning neuronal transporter for dopamine: Kinetic mechanisms and effects of amphetamines, cocaine and methylphenidate
    • Schenk, J.O. (2002) The functioning neuronal transporter for dopamine: kinetic mechanisms and effects of amphetamines, cocaine and methylphenidate. Prog. Drug Res., 59, 111-131.
    • (2002) Prog. Drug Res , vol.59 , pp. 111-131
    • Schenk, J.O.1
  • 49
    • 0022270177 scopus 로고
    • 3H]Threo-(+/-)-methylphenidate binding to 3,4-dihydroxyphenylethylamine uptake sites in corpus striatum: Correlation with the stimulant properties of ritalinic acid esters
    • Schweri, M.M., Skolnick, P., Rafferty, M.F., Rice, K.C., Janowsky, A.J., Paul, S.M. (1985) [3H]Threo-(+/-)-methylphenidate binding to 3,4-dihydroxyphenylethylamine uptake sites in corpus striatum: correlation with the stimulant properties of ritalinic acid esters. J. Neurochem., 45, 1062-1070.
    • (1985) J. Neurochem , vol.45 , pp. 1062-1070
    • Schweri, M.M.1    Skolnick, P.2    Rafferty, M.F.3    Rice, K.C.4    Janowsky, A.J.5    Paul, S.M.6
  • 50
    • 0030211275 scopus 로고    scopus 로고
    • Successful treatment of giggle incontinence with methylphenidate
    • Sher, P.K., Reinberg, Y. (1996) Successful treatment of giggle incontinence with methylphenidate. J. Urol., 156, 656-658.
    • (1996) J. Urol , vol.156 , pp. 656-658
    • Sher, P.K.1    Reinberg, Y.2
  • 51
    • 0031846705 scopus 로고    scopus 로고
    • Carrier-mediated release, transport rates, and charge transfer induced by amphetamine, tyramine, and dopamine in mammalian cells transfected with the human dopamine transporter
    • Sitte, H.H., Huck, S., Reither, H., Boehm, S., Singer, E.A., Pifl, C. (1998) Carrier-mediated release, transport rates, and charge transfer induced by amphetamine, tyramine, and dopamine in mammalian cells transfected with the human dopamine transporter. J. Neurochem., 71, 1289-1297.
    • (1998) J. Neurochem , vol.71 , pp. 1289-1297
    • Sitte, H.H.1    Huck, S.2    Reither, H.3    Boehm, S.4    Singer, E.A.5    Pifl, C.6
  • 52
    • 0031036030 scopus 로고    scopus 로고
    • Multiple ionic conductances of the human dopamine transporter: The actions of dopamine and psychostimulants
    • Sonders, M.S., Zhu, S.J., Zahniser, N.R., Kavanaugh, M.P., Amara, S.G. (1997) Multiple ionic conductances of the human dopamine transporter: the actions of dopamine and psychostimulants. J. Neurosci., 17, 960-974.
    • (1997) J. Neurosci , vol.17 , pp. 960-974
    • Sonders, M.S.1    Zhu, S.J.2    Zahniser, N.R.3    Kavanaugh, M.P.4    Amara, S.G.5
  • 53
    • 0029062077 scopus 로고
    • A double-blind, crossover comparison of methylphenidate and placebo in adults with childhood-onset attention-deficit hyperactivity disorder
    • Spencer, T., Wilens, T., Biederman, J., Faraone, S.V., Ablon, J.S., Lapey, K. (1995) A double-blind, crossover comparison of methylphenidate and placebo in adults with childhood-onset attention-deficit hyperactivity disorder. Arch. Gen Psychiatry, 52, 434-443.
    • (1995) Arch. Gen Psychiatry , vol.52 , pp. 434-443
    • Spencer, T.1    Wilens, T.2    Biederman, J.3    Faraone, S.V.4    Ablon, J.S.5    Lapey, K.6
  • 54
    • 0028153669 scopus 로고
    • Visualizing dopamine and serotonin transporters in the human brain with the potent cocaine analogue [125I]RTI-55: In vitro binding and autoradiographic characterization
    • Staley, J.K., Basile, M., Flynn, D.D., Mash, D.C. (1994) Visualizing dopamine and serotonin transporters in the human brain with the potent cocaine analogue [125I]RTI-55: in vitro binding and autoradiographic characterization. J. Neurochem., 62, 549-556.
    • (1994) J. Neurochem , vol.62 , pp. 549-556
    • Staley, J.K.1    Basile, M.2    Flynn, D.D.3    Mash, D.C.4
  • 55
    • 0037051145 scopus 로고    scopus 로고
    • Pharmacokinetic and pharmacodynamic properties of stimulants: Implications for the design of new treatments for ADHD
    • Swanson, J.M., Volkow, N.D. (2002) Pharmacokinetic and pharmacodynamic properties of stimulants: implications for the design of new treatments for ADHD. Behav. Brain Res., 130, 73-78.
    • (2002) Behav. Brain Res , vol.130 , pp. 73-78
    • Swanson, J.M.1    Volkow, N.D.2
  • 56
    • 42449144406 scopus 로고    scopus 로고
    • The newly synthesized pool of dopamine determines the severity of methamphetamine-induced neurotoxicity
    • Thomas, D.M., Francescutti-Verbeem, D.M., Kuhn, D.M. (2008) The newly synthesized pool of dopamine determines the severity of methamphetamine-induced neurotoxicity. J. Neurochem., 105, 605-616.
    • (2008) J. Neurochem , vol.105 , pp. 605-616
    • Thomas, D.M.1    Francescutti-Verbeem, D.M.2    Kuhn, D.M.3
  • 57
    • 0020655430 scopus 로고
    • Inhibition of dopamine synthesis in striatal synaptosomes by lisuride: Stereospecific reversal by (-)-sulpiride
    • Tissari, A.H., Atzori, L., Galdieri, M.T. (1983) Inhibition of dopamine synthesis in striatal synaptosomes by lisuride: stereospecific reversal by (-)-sulpiride. Naunyn Schmiedebergs Arch. Pharmacol., 322, 89-91.
    • (1983) Naunyn Schmiedebergs Arch. Pharmacol , vol.322 , pp. 89-91
    • Tissari, A.H.1    Atzori, L.2    Galdieri, M.T.3
  • 58
    • 6944240096 scopus 로고    scopus 로고
    • Dopamine D2 receptor activation increases vesicular dopamine uptake and redistributes vesicular monoamine transporter-2 protein
    • Truong, J.G., Newman, A.H., Hanson, G.R., Fleckenstein, A.E. (2004) Dopamine D2 receptor activation increases vesicular dopamine uptake and redistributes vesicular monoamine transporter-2 protein. Eur. J. Pharmacol., 504, 27-32.
    • (2004) Eur. J. Pharmacol , vol.504 , pp. 27-32
    • Truong, J.G.1    Newman, A.H.2    Hanson, G.R.3    Fleckenstein, A.E.4
  • 60
    • 0028942636 scopus 로고
    • Methylphenidate for the management of somatization in terminal cancer patients
    • Vigano, A., Watanabe, S., Bruera, E. (1995) Methylphenidate for the management of somatization in terminal cancer patients. J. Pain Symptom Manage., 10, 167-170.
    • (1995) J. Pain Symptom Manage , vol.10 , pp. 167-170
    • Vigano, A.1    Watanabe, S.2    Bruera, E.3
  • 61
    • 1642293724 scopus 로고    scopus 로고
    • Mechanism of action of methylphenidate: Insights from PET imaging studies
    • Volkow, N.D., Fowler, J.S., Wang, G., Ding, Y., Gatley, S.J. (2002) Mechanism of action of methylphenidate: insights from PET imaging studies. J. Atten. Disord., 6, S31-43.
    • (2002) J. Atten. Disord , vol.6
    • Volkow, N.D.1    Fowler, J.S.2    Wang, G.3    Ding, Y.4    Gatley, S.J.5
  • 64
    • 22544457158 scopus 로고    scopus 로고
    • Methylphenidate analogs with behavioral differences interact differently with arginine residues on the dopamine transporter in rat striatum
    • Volz, T.J., Bjorklund, N.L., Schenk, J.O. (2005) Methylphenidate analogs with behavioral differences interact differently with arginine residues on the dopamine transporter in rat striatum. Synapse, 57, 175-178.
    • (2005) Synapse , vol.57 , pp. 175-178
    • Volz, T.J.1    Bjorklund, N.L.2    Schenk, J.O.3
  • 65
    • 35548951840 scopus 로고    scopus 로고
    • Methylphenidate administration alters vesicular monoamine transporter-2 function in cytoplasmic and membrane-associated vesicles
    • Volz, T.J., Farnsworth, S.J., King, J.L., Riddle, E.L., Hanson, G.R., Fleckenstein, A.E. (2007) Methylphenidate administration alters vesicular monoamine transporter-2 function in cytoplasmic and membrane-associated vesicles. J. Pharmacol. Exp. Ther., 323, 738-745.
    • (2007) J. Pharmacol. Exp. Ther , vol.323 , pp. 738-745
    • Volz, T.J.1    Farnsworth, S.J.2    King, J.L.3    Riddle, E.L.4    Hanson, G.R.5    Fleckenstein, A.E.6
  • 66
    • 33847311755 scopus 로고    scopus 로고
    • Methamphetamine-induced alterations in monoamine transport: Implications for neurotoxicity, neuroprotection and treatment
    • Volz, T.J., Fleckenstein, A.E., Hanson, G.R. (2007) Methamphetamine-induced alterations in monoamine transport: implications for neurotoxicity, neuroprotection and treatment. Addiction, 102, 44-48.
    • (2007) Addiction , vol.102 , pp. 44-48
    • Volz, T.J.1    Fleckenstein, A.E.2    Hanson, G.R.3
  • 67
    • 33748587861 scopus 로고    scopus 로고
    • Kinetic analysis of developmental changes in vesicular monoamine transporter-2 function
    • Volz, T.J., Hanson, G.R., Fleckenstein, A.E. (2006) Kinetic analysis of developmental changes in vesicular monoamine transporter-2 function. Synapse, 60, 474-477.
    • (2006) Synapse , vol.60 , pp. 474-477
    • Volz, T.J.1    Hanson, G.R.2    Fleckenstein, A.E.3
  • 68
    • 33745035201 scopus 로고    scopus 로고
    • Measurement of kinetically resolved vesicular dopamine uptake and efflux using rotating disk electrode voltammetry
    • Volz, T.J., Hanson, G.R., Fleckenstein, A.E. (2006) Measurement of kinetically resolved vesicular dopamine uptake and efflux using rotating disk electrode voltammetry. J. Neurosci. Methods, 155, 109-115.
    • (2006) J. Neurosci. Methods , vol.155 , pp. 109-115
    • Volz, T.J.1    Hanson, G.R.2    Fleckenstein, A.E.3
  • 69
    • 34247590307 scopus 로고    scopus 로고
    • The role of the plasmalemmal dopamine and vesicular monoamine transporters in methamphetamine-induced dopaminergic deficits
    • Volz, T.J., Hanson, G.R., Fleckenstein, A.E. (2007) The role of the plasmalemmal dopamine and vesicular monoamine transporters in methamphetamine-induced dopaminergic deficits. J. Neurochem., 101, 883-888.
    • (2007) J. Neurochem , vol.101 , pp. 883-888
    • Volz, T.J.1    Hanson, G.R.2    Fleckenstein, A.E.3
  • 70
    • 2342503276 scopus 로고    scopus 로고
    • Covalent and noncovalent chemical modifications of arginine residues decrease dopamine transporter activity
    • Volz, T.J., Kim, M., Schenk, J.O. (2004) Covalent and noncovalent chemical modifications of arginine residues decrease dopamine transporter activity. Synapse, 52, 272-282.
    • (2004) Synapse , vol.52 , pp. 272-282
    • Volz, T.J.1    Kim, M.2    Schenk, J.O.3
  • 71
    • 26644465295 scopus 로고    scopus 로고
    • A comprehensive atlas of the topography of functional groups of the dopamine transporter
    • Volz, T.J., Schenk, J.O. (2005) A comprehensive atlas of the topography of functional groups of the dopamine transporter. Synapse, 58, 72-94.
    • (2005) Synapse , vol.58 , pp. 72-94
    • Volz, T.J.1    Schenk, J.O.2
  • 72
    • 0018881202 scopus 로고
    • Long-lasting depletions of striatal dopamine and loss of dopamine uptake sites following repeated administration of methamphetamine
    • Wagner, G.C., Ricaurte, G.A., Seiden, L.S., Schuster, C.R., Miller, R.J., Westley, J. (1980) Long-lasting depletions of striatal dopamine and loss of dopamine uptake sites following repeated administration of methamphetamine. Brain Res., 181, 151-160.
    • (1980) Brain Res , vol.181 , pp. 151-160
    • Wagner, G.C.1    Ricaurte, G.A.2    Seiden, L.S.3    Schuster, C.R.4    Miller, R.J.5    Westley, J.6
  • 73
    • 41349085786 scopus 로고    scopus 로고
    • Mechanisms by which amphetamine redistributes dopamine out of vesicles: A computational study
    • Wallace, L.J., Connell, L.E. (2008) Mechanisms by which amphetamine redistributes dopamine out of vesicles: A computational study. Synapse, 62, 370-378.
    • (2008) Synapse , vol.62 , pp. 370-378
    • Wallace, L.J.1    Connell, L.E.2
  • 74
    • 0031958698 scopus 로고    scopus 로고
    • Relationships between the catechol substrate binding site and amphetamine, cocaine, and mazindol binding sites in a kinetic model of the striatal transporter of dopamine in vitro
    • Wayment, H., Meiergerd, S.M., Schenk, J.O. (1998) Relationships between the catechol substrate binding site and amphetamine, cocaine, and mazindol binding sites in a kinetic model of the striatal transporter of dopamine in vitro. J. Neurochem., 70, 1941-1949.
    • (1998) J. Neurochem , vol.70 , pp. 1941-1949
    • Wayment, H.1    Meiergerd, S.M.2    Schenk, J.O.3
  • 75
    • 0033010337 scopus 로고    scopus 로고
    • Effects of methylphenidate analogues on phenethylamine substrates for the striatal dopamine transporter: Potential as amphetamine antagonists?
    • Wayment, H.K., Deutsch, H., Schweri, M.M., Schenk, J.O. (1999) Effects of methylphenidate analogues on phenethylamine substrates for the striatal dopamine transporter: potential as amphetamine antagonists? J. Neurochem., 72, 1266-1274.
    • (1999) J. Neurochem , vol.72 , pp. 1266-1274
    • Wayment, H.K.1    Deutsch, H.2    Schweri, M.M.3    Schenk, J.O.4
  • 76
    • 0026627919 scopus 로고
    • Methylphenidate as a treatment for depression in acquired immunodeficiency syndrome: An n-of-1 trial
    • White, J.C., Christensen, J.F., Singer, C.M. (1992) Methylphenidate as a treatment for depression in acquired immunodeficiency syndrome: an n-of-1 trial. J. Clin. Psychiatry, 53, 153-156.
    • (1992) J. Clin. Psychiatry , vol.53 , pp. 153-156
    • White, J.C.1    Christensen, J.F.2    Singer, C.M.3
  • 77
    • 0034667644 scopus 로고    scopus 로고
    • Effect of temperature on dopamine transporter function and intracellular accumulation of methamphetamine: Implications for methamphetamine-induced dopaminergic neurotoxicity
    • Xie, T., McCann, U.D., Kim, S., Yuan, J., Ricaurte, G.A. (2000) Effect of temperature on dopamine transporter function and intracellular accumulation of methamphetamine: implications for methamphetamine-induced dopaminergic neurotoxicity. J. Neurosci., 20, 7838-7845.
    • (2000) J. Neurosci , vol.20 , pp. 7838-7845
    • Xie, T.1    McCann, U.D.2    Kim, S.3    Yuan, J.4    Ricaurte, G.A.5
  • 78
    • 0025923503 scopus 로고
    • Interactions of [3H]amphetamine with rat brain synaptosomes. II. Active transport
    • Zaczek, R., Culp, S., De Souza, E.B. (1991) Interactions of [3H]amphetamine with rat brain synaptosomes. II. Active transport. J. Pharmacol. Exp. Ther., 257, 830-835.
    • (1991) J. Pharmacol. Exp. Ther , vol.257 , pp. 830-835
    • Zaczek, R.1    Culp, S.2    De Souza, E.B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.