Therapeutic doses of oral methylphenidate significantly increase extracellular dopamine in the human brain.

The Journal of neuroscience : the official journal of the Society for Neuroscience

Volumn 21, Issue 2, 2001, Pages

  Volkow, N D ^a   Wang, G ^a   Fowler, J S ^a   Logan, J ^a   Gerasimov, M ^a   Maynard, L ^a   Ding, Y ^a   Gatley, S J ^a   Gifford, A ^a   Franceschi, D ^a  

^a BROOKHAVEN NATIONAL LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBON; CARRIER PROTEIN; DOPAMINE; DOPAMINE 2 RECEPTOR; DOPAMINE RECEPTOR BLOCKING AGENT; DOPAMINE TRANSPORTER; MEMBRANE PROTEIN; METHYLPHENIDATE; NERVE PROTEIN; RACLOPRIDE;

ADULT; ARTICLE; BEHAVIOR; BINDING COMPETITION; BLOOD; BRAIN; CEREBELLUM; CLINICAL TRIAL; COMPUTER ASSISTED EMISSION TOMOGRAPHY; CORPUS STRIATUM; DRUG ANTAGONISM; DRUG EFFECT; EXTRACELLULAR SPACE; GENETIC VARIABILITY; HEART RATE; HUMAN; MALE; METABOLISM; ORAL DRUG ADMINISTRATION; SCINTISCANNING;

ADMINISTRATION, ORAL; ADULT; BEHAVIOR; BINDING, COMPETITIVE; BRAIN; CARBON RADIOISOTOPES; CARRIER PROTEINS; CEREBELLUM; CORPUS STRIATUM; DOPAMINE; DOPAMINE ANTAGONISTS; DOPAMINE PLASMA MEMBRANE TRANSPORT PROTEINS; EXTRACELLULAR SPACE; HEART RATE; HUMANS; MALE; MEMBRANE GLYCOPROTEINS; MEMBRANE TRANSPORT PROTEINS; METHYLPHENIDATE; NERVE TISSUE PROTEINS; RACLOPRIDE; RECEPTORS, DOPAMINE D2; TOMOGRAPHY, EMISSION-COMPUTED; VARIATION (GENETICS);

MLCS; MLOWN;

EID: 0035864193     PISSN: None     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/jneurosci.21-02-j0001.2001     Document Type: Article

References (0)