A fitness-based interferential genetics approach using hypertoxic/inactive gene alleles as references

Molecular Genetics and Genomics

Volumn 281, Issue 4, 2009, Pages 437-445

  Daniel, Jacques H ^a  

^a CNRS   (France)

Author keywords

Fitness based interferential genetics; Ino4 transcription factor; Interactive inactive allele; Macromolecular network; Protein kinase C

Indexed keywords

PROTEIN KINASE C; FUNGAL DNA; PKC1 PROTEIN, S CEREVISIAE; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; RHO1 PROTEIN, S CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEIN;

ALLELE; ARTICLE; FUNCTIONAL GENOMICS; MACROMOLECULE; MUTAGENESIS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; WILD TYPE; FUNGAL GENE; GENE REGULATORY NETWORK; GENETIC COMPLEMENTATION; GENETIC PROCEDURES; GENETICS; METABOLISM; NUCLEOTIDE SEQUENCE; SACCHAROMYCES CEREVISIAE;

ALLELES; BASE SEQUENCE; DNA, FUNGAL; GENE REGULATORY NETWORKS; GENES, FUNGAL; GENETIC COMPLEMENTATION TEST; GENETIC TECHNIQUES; METABOLIC NETWORKS AND PATHWAYS; MUTAGENESIS; POLYMERASE CHAIN REACTION; PROTEIN KINASE C; RHO GTP-BINDING PROTEINS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS;

EID: 66149102114     PISSN: 16174615     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00438-008-0416-4     Document Type: Article

References (39)

1. D Alvaro M Lisby R Rothstein 2007 Genome-wide analysis of Rad52 foci reveals diverse mechanisms impacting recombination PLos Genet 3 2439 2449
2. D Balciunas H Ronne 1999 Yeast genes GIS1-4: multicopy suppressors of the Gal- phenotype of snf1 mig1 srb8/10/11 cells Mol Gen Genet 262 589 599 (Pubitemid 30018801)
3. JD Boeke F Lacroute GR Fink 1984 A positive selection for mutants lacking orotidine-5-phosphate dicarboxylase activity in yeast: 5-fluoro-orotic acid resistance Mol Gen Genet 197 345 346
4. M Carlson D Botstein 1982 Two differentially regulated mRNAs with different 5? ends encode secreted and intracellular forms of yeast invertase Cell 28 145 154 (Pubitemid 12223317)
5. J Chant K Corrado J Pringle I Herskowitz 1991 Yeast BUD5, encoding a putative GDP-GTP exchange factor, is necessary for bud-site selection and interacts with bud-formation gene BEM1 Cell 65 1213 1224 (Pubitemid 121001334)
6. M Chen JM Lopes 2007 Multiple basic helix-loop-helix proteins regulate expression of the ENO1 gene of Saccharomyces cerevisiae Eukaryot Cell 6 786 796 (Pubitemid 46835042)
7. J Daniel 1993 Potentially rapid walking in cellular regulatory networks using the gene-gene interference method Mol Gen Genet 240 245 257 (Pubitemid 23240423)
8. J Daniel 1995 DNA insertion system for complex yeast shuttle vectors Curr Genet 27 309 311
9. J Daniel 1996 Detection of antagonistic cellular regulatory functions by the gene-gene interference method in yeast Curr Genet 29 114 121 (Pubitemid 26034722)
10. J Daniel 1996 Measuring the toxic effects of high gene dosage in yeast cells Mol Gen Genet 253 393 396 (Pubitemid 27023198)
11. J Daniel 2005 Sir-dependent downregulation of various aging processes Mol Gen Genom 274 539 547 (Pubitemid 41721162)
12. J Daniel 2007 Direct in vivo access to potential gene targets of the RPD3 histone deacetylase using fitness-based interferential genetics Yeast 24 575 587 (Pubitemid 47082724)
13. J Daniel 2008 A potentially general method for the in-vivo selection of inhibitory peptides targeted at a specific protein using yeast Curr Genet 53 373 379
14. MA de la Torre Ruiz NF Lowndes 2000 DUN1 defines one branch downstream of RAD53 for transcription and DNA damage repair in Saccharomyces cerevisiae FEBS Lett 485 205 206
15. RC Dickson 2008 New insights into sphingolipid metabolism and function in budding yeast J Lipid Res 49 909 920
16. CS Fong MD Temple N Alic J Chiu M Durchdewald GW Thorpe VJ Higgins IW Dawes 2008 Oxidant-induced cell-cycle delay in Saccharomyces cerevisiae: the involvement of the SWI4 transcription factor FEMS Yeast Res 8 386 399 (Pubitemid 351579650)
17. R Gardner CW Putnam T Weinert 1999 RAD53, DUN1 and PDS1 define two parallel G2/M checkpoint pathways in budding yeast EMBO J 18 3178 3185
18. V Ghugtyal C Vionnet C Roubaty A Conzelmann 2007 CWH43 is required for the introduction of ceramides into GPI anchors in Saccharomyces cerevisiae Mol Microbiol 65 1493 1502 (Pubitemid 47347832)
19. H-L Ho Y-S Shiau M-Y Chen 2005 Saccharomyces cerevisiae TSC11/AVO3 participates in regulating cell integrity and functionally interacts with components of the Tor2 complex Curr Genet 47 273 288 (Pubitemid 40723968)
20. H Ito Y Fukuda K Murata A Kumura 1983 Transformation in yeast cells treated with alkali cations J Bacteriol 153 163 168
21. SA Jesch X Zhao MT Wells SA Henry 2005 Genome-wide analysis reveals inosotol, not choline, as the major effector of Ino2p-Ino4p and unfolded protein response target gene expression in yeast J Biol Chem 280 9106 9118 (Pubitemid 40409605)
22. DE Levin E Bartlett-Heubusch 1992 Mutants in the S. cerevisiae PKC1 gene display a cell cycle-specific osmotic stability defect J Cell Biol 116 1221 1229
23. DE Levin 2005 Cell wall integrity signaling in Saccharomyces cerevisiae Microbiol Mol Biol Rev 69 262 291 (Pubitemid 40847940)
24. BS Loewy SA Henry 1984 The INO2 and INO4 loci of Saccharomyces cerevisiae are pleiotropic genes Mol Cell Biol 4 2479 2485 (Pubitemid 15212263)
25. O Odat S Matta H Khalil SC Kampranis R Pfau P Tsichlis AM Makris 2007 Old yellow enzymes, highly homologous FMN oxidoreductases with modulating roles in oxidative stress and programmed cell death in yeast J Biol Chem 282 36010 36023 (Pubitemid 350277144)
26. P Orlean AK Menon 2007 GPI anchoring of protein in yeast and mammalian cells, or: how we learned to stop worrying and love glycophospholipids J Lipid Res 48 993 1011 (Pubitemid 46708667)
27. G Paravicini M Cooper L Friedli DJ Smith JL Carpentier LS Klig MA Payton 1992 The osmotic integrity of the yeast cell requires a functional PKC1 gene product Mol Cell Biol 12 4896 4905
28. J Reinders 2007 Profiling phosphoproteins of yeast mitochondria reveals a role of phosphorylation in assembly of the ATP synthase Mol Cell Proteom 6 1896 1906 (Pubitemid 350201867)
29. M Rep V Reiser U Gartner JM Thevelein S Hohmann G Ammerer H Ruis 1999 Osmotic stress-induced gene expression in Saccharomyces cerevisiae requires Msn1p and the novel nuclear factor Hot1p Mol Cell Biol 19 5474 5485 (Pubitemid 29339905)
30. KA Robinson JI Koepke M Khadorawala JM Lopes 2000 A network of yeast basic helix-loop-helix interactions Nucleic Acids Res 28 4460 4466 (Pubitemid 30838242)
31. KA Robinson JM Lopes 2000 Saccharomyces cerevisiae basic helix-loop-helix proteins regulate diverse biological processes Nucleic Acids Res 28 1499 1505 (Pubitemid 30160561)
32. Sambrook J, Fritsch EF, Maniatis T (1989) Molecular cloning: a laboratory manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor
33. Sherman F, Fink G, Hicks J (1987) Methods in Yeast Genetics: A Laboratory Course Manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor
34. H Shimoi H Kitagaki H Ohmori Y Iimura K Ito 1998 Sed1p is a major cell wall protein of Saccharomyces cerevisiae in the stationary phase and is involved in lytic enzyme resistance J Bacteriol 180 3381 3387 (Pubitemid 28307212)
35. X Su W Dowhan 2006 Regulation of cardiolipin synthase levels in Saccharomyces cerevisiae Yeast 23 279 291
36. K Tan H Feizi C Luo SH Fan T Ravasi TG Ideker 2008 A systems approach to delineate functions of paralogous transcription factors: role of the Yap family in the DNA damage response Proc Natl Acad Sci USA 105 2934 2939 (Pubitemid 351723647)
37. CT Workman CH Mak S McCuine J-B Tagne M Agarwal O Ozier TJ Begley LD Samson T Ideker 2006 A system approach to mapping DNA damage response pathways Science 312 1054 1059 (Pubitemid 43752915)
38. ZB Xu D Chaudhari S Olland S Wolfrom R Czerwinski K Malakian L Lin ML Stahl D Joseph-McCarthy C Benander L Fitz R Greco WS Somers L Mosvak 2004 Catalytic domain crystal structure of protein kinase C-θ (PKCθ) J Biol Chem 279 50401 50409 (Pubitemid 39577858)
39. S Yoshida E Ikeda I Uno H Mitsuzawa 1992 Characterization of a staurosporine- and temperature-sensitive mutant, stt1, of Saccharomyces cerevisiae: STT1 is allelic to PKC1 Mol Gen Genet 231 337 344