Regulation of cardiolipin synthase levels in Saccharomyces cerevisiae

Yeast

Volumn 23, Issue 4, 2006, Pages 279-291

  Su, Xuefeng ^a   Dowhan, William ^a  

^a UNIVERSITY OF TEXAS   (United States)

Author keywords

galactosidase; Cardiolipin; CRD1 gene expression; Diauxic shift; Inositol; Mitochondria; Phosphatidylglycerol; Saccharomyces cerevisiae

Indexed keywords

BETA GALACTOSIDASE; CARDIOLIPIN SYNTHASE; CRD1 PROTEIN; DIMER; GENE PRODUCT; GLUCOSE; GLYCEROL; INO2 PROTEIN; INO4 PROTEIN; INOSITOL; MESSENGER RNA; PHOSPHATIDYLGLYCEROL; REGULATOR PROTEIN; SYNTHETASE; UNCLASSIFIED DRUG;

5' UNTRANSLATED REGION; ARTICLE; CATALYSIS; CELL GROWTH; CONTROLLED STUDY; CULTURE MEDIUM; ENZYME REGULATION; GENE EXPRESSION REGULATION; GENE REPRESSION; MITOCHONDRIAL MEMBRANE; MITOCHONDRIAL RESPIRATION; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN LOCALIZATION; PROTEIN SYNTHESIS; REPORTER GENE; SACCHAROMYCES CEREVISIAE; TRANSCRIPTION REGULATION; TRANSLATION REGULATION; WILD TYPE;

BASE SEQUENCE; ELECTROPHORETIC MOBILITY SHIFT ASSAY; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE EXPRESSION REGULATION, FUNGAL; INOSITOL; MEMBRANE PROTEINS; MITOCHONDRIA; MOLECULAR SEQUENCE DATA; PHOSPHATIDYLGLYCEROLS; PHOSPHORIC MONOESTER HYDROLASES; PROMOTER REGIONS (GENETICS); PROTEIN BIOSYNTHESIS; SACCHAROMYCES CEREVISIAE; TRANSCRIPTION INITIATION SITE; TRANSCRIPTION, GENETIC; TRANSFERASES (OTHER SUBSTITUTED PHOSPHATE GROUPS);

SACCHAROMYCES CEREVISIAE;

EID: 33645751436     PISSN: 0749503X     EISSN: 10970061     Source Type: Journal    
DOI: 10.1002/yea.1352     Document Type: Article

References (68)

1. Amati B, Land H. 1994. Myc-Max-Mad: a transcription factor network controlling cell cycle progression, differentiation and death. Curr Opin Genet Dev 4: 102-108.
2. Anderson MS, Lopes JM. 1996. Carbon source regulation of PIS1 gene expression in Saccharomyces cerevisiae involves the MCM1 gene and the two-component regulatory gene, SLN1. J Biol Chem 271: 26 596-26 601.
3. Ardail D, Lerme F, Louisot P. 1991. Involvement of contact sites in phosphatidylserine import into liver mitochondria. J Biol Chem 266: 7978-7981.
4. Bailis AM, Poole MA, Carman GM, Henry SA. 1987. The membrane-associated enzyme phosphatidylserine synthase is regulated at the level of mRNA abundance. Mol Cell Biol 7: 167-176.
5. Battelli D, Bellei M, Arrigoni-Martelli E, Muscatello U, Bobyleva V. 1992. Interaction of carnitine with mitochondrial cardiolipin. Biochim Biophys Acta 1117: 33-36.
6. Biswas SB, Biswas EE. 1990. ARS binding factor I of the yeast Saccharomyces cerevisiae binds to sequences in telomeric and nontelomeric autonomously replicating sequences. Mol Cell Biol 10: 810-815.
7. Block-Alper L, Webster P, Zhou X, et al. 2002. IN02, a positive regulator of lipid biosynthesis, is essential for the formation of inducible membranes in yeast. Mol Biol Cell 13: 40-51.
8. Carman GM, Henry SA. 1989. Phospholipid biosynthesis in yeast. Annu Rev Biochem 58: 635-669.
9. Chang SC, Heacock PN, Clancey CJ, Dowhan W. 1998a. The PEL1 gene (renamed PGS1) encodes the phosphatidylglycerol-phosphate synthase of Saccharomyces cerevisiae. J Biol Chem 273: 9829-9836.
10. Chang SC, Heacock PN, Mileykovskaya E, Voelker DR, Dowhan W. 1998b. Isolation and characterization of the gene (CLS1) encoding cardiolipin synthase in Saccharomyces cerevisiae. J Biol Chem 273: 14 933-14 941.
11. Chomczynski P. 1993. A reagent for the single-step simultaneous isolation of RNA, DNA and proteins from cell and tissue samples. Biotechniques 15: 532-534, 536-537.
12. 1H-NMR study. FEBS Lett 373: 239-244.
13. 31P nuclear magnetic resonance spectroscopy. J Biol Chem 265: 19 434-19 440.
14. Eilers M, Endo T, Schatz G. 1989. Adriamycin, a drug interacting with acidic phospholipids, blocks import of precursor proteins by isolated yeast mitochondria. J Biol Chem 264: 2945-2950.
15. Endo T, Eilers M, Schatz G. 1989. Binding of a tightly folded artificial mitochondrial precursor protein to the mitochondrial outer membrane involves a lipid-mediated conformational change. J Biol Chem 264: 2951-2956.
16. Esposti MD. 2002. Lipids, cardiolipin and apoptosis: a greasy licence to kill. Cell Death Diff 9: 234-236.
17. Frohman MA, Dush MK, Martin GR. 1988. Rapid production of full-length cDNAs from rare transcripts: amplification using a single gene-specific oligonucleotide primer. Proc Natl Acad Sci USA 85: 8998-9002.
18. Fry M, Green DE. 1981. Cardiolipin requirement for electron transfer in complex I and III of the mitochondrial respiratory chain. J Biol Chem 256: 1874-1880.
19. Gallet PF, Petit JM, Maftah A, Zachowski A, Julien R. 1997. Asymmetrical distribution of cardiolipin in yeast inner mitochondrial membrane triggered by carbon catabolite repression. Biochem J 324: 627-634.
20. Gaynor PM, Hubbell S, Schmidt AJ, et al. 1991. Regulation of phosphatidylglycerolphosphate synthase in Saccharomyces cerevisiae by factors affecting mitochondrial development. J Bacteriol 173: 6124-6131.
21. Gohil VM, Hayes P, Matsuyama S, et al. 2004. Cardiolipin biosynthesis and mitochondrial respiratory chain function are interdependent. J Biol Chem 279: 42 612-42 618.
22. Greenberg ML, Hubbell S, Lam C. 1988. Inositol regulates phosphatidylglycerolphosphate synthase expression in Saccharomyces cerevisiae. Mol Cell Biol 8: 4773-4779.
23. Greenberg ML, Lopes JM. 1996. Genetic regulation of phospholipid biosynthesis in Saccharomyces cerevisiae. Microbiol Rev 60: 1-20.
24. Gygi SP, Rochon Y, Franza BR, Aebersold R. 1999. Correlation between protein and mRNA abundance in yeast. Mol Cell Biol 19: 1720-1730.
25. Haines TH, Dencher NA. 2002. Cardiolipin: a proton trap for oxidative phosphorylation. FEBS Lett 528: 35-39.
26. Hajek P, Bedwell DM. 1994. Characterization of the mitochondrial binding and import properties of purified yeast F1-ATPase beta subunit precursor. Import requires external ATP. J Biol Chem 269: 7192-7200.
27. Hatch GM. 1996. Regulation of cardiolipin biosynthesis in the heart. Mol Cell Biol 159: 139-148.
28. He Q, Greenberg ML. 2004. Post-translational regulation of phosphatidylglycerolphosphate synthase in response to inositol. Mol Microbiol 53: 1243-1249.
29. Hirsch JP, Henry SA. 1986. Expression of the Saccharomyces cerevisiae inositol-1-phosphate synthase (INO1) gene is regulated by factors that affect phospholipid synthesis. Mol Cell Biol 6: 3320-3328.
30. Hoffmann B, Stockl A, Schlame M, Beyer K, Klingenberg M. 1994. The reconstituted ADP/ATP carrier activity has an absolute requirement for cardiolipin as shown in cysteine mutants. J Biol Chem 269: 1940-1944.
31. Hoshizaki DK, Hill JE, Henry SA. 1990. The Saccharomyces cerevisiae INO4 gene encodes a small, highly basic protein required for derepression of phospholipid biosynthetic enzymes. J Biol Chem 265: 4736-4745.
32. Jakovcic S, Getz GS, Rabinowitz M, Jakob H, Swift H. 1971. Cardiolipin content of wild-type and mutant yeasts in relation to mitochondrial function and development. J Cell Biol 48: 490-502.
33. Janitor M, Subik J. 1993. Molecular cloning of the PEL1 gene of Saccharomyces cerevisiae that is essential for the viability of petite mutants. Curr Genet 24: 307-312.
34. Jiang F, Gu Z, Granger JM, Greenberg ML. 1999. Cardiolipin synthase expression is essential for growth at elevated temperature and is regulated by factors affecting mitochondrial development. Mol Microbiol 31: 373-379.
35. Jiang F, Rizavi HS, Greenberg ML. 1997. Cardiolipin is not essential for the growth of Saccharomyces cerevisiae on fermentable or non-fermentable carbon sources. Mol Microbiol 26: 481-491.
36. Kelly BL, Greenberg ML. 1990. Characterization and regulation of phosphatidylglycerolphosphate phosphatase in Saccharomyces cerevisiae. Biochim Biophys Acta 1046: 144-150.
37. Kirkland RA, Adibhatla RM, Hatcher JF, Franklin JL. 2002. Loss of cardiolipin and mitochondria during programmed neuronal death: evidence of a role for lipid peroxidation and autophagy. Neuroscience 115: 587-602.
38. Koshkin V, Greenberg ML. 2000. Oxidative phosphorylation in cardiolipin-lacking yeast mitochondria. Biochem J 347: 687-691.
39. Kriska T, Korytowski W, Girotti AW. 2005. Role of mitochondrial cardiolipin peroxidation in apoptotic photokilling of 5-aminolevulinate-treated tumor cells. Arch Biochem Biophys 433: 435-446.
40. Lange C, Nett JH, Trumpower BL, Hunte C. 2001. Specific roles of protein-phospholipid interactions in the yeast cytochrome bc1 complex structure. EMBO J 20: 6591-6600.
41. Loewy BS, Henry SA. 1984. The INO2 and INO4 loci of Saccharomyces cerevisiae are pleiotropic regulatory genes. Mol Cell Biol 4: 2479-2485.
42. McGraw P, Henry SA. 1989. Mutations in the Saccharomyces cerevisiae opi3 gene: effects on phospholipid methylation, growth and cross-pathway regulation of inositol synthesis. Genetics 122: 317-330.
43. McMillin JB, Dowhan W. 2002. Cardiolipin and apoptosis. Biochim Biophys Acta 1585: 97-107.
44. Mende P, Huther FJ, Kadenbach B. 1983. Specific and reversible activation and inactivation of the mitochondrial phosphate carrier by cardiolipin and nonionic detergents, respectively. FEBS Lett 158: 331-334.
45. Morlock KR, Lin YP, Carman GM. 1988. Regulation of phosphatidate phosphatase activity by inositol in Saccharomyces cerevisiae. J Bacteriol 170: 3561-3566.
46. Nakagawa Y. 2004. Initiation of apoptotic signal by the peroxidation of cardiolipin of mitochondria. Ann N Y Acad Sci 1011: 177-184.
47. Nikoloff DM, McGraw P, Henry SA. 1992. The INO2 gene of Saccharomyces cerevisiae encodes a helix-loop-helix protein that is required for activation of phospholipid synthesis. Nucleic Acids Res 20: 3253.
48. Ostrander DB, Zhang M, Mileykovskaya E, Rho M, Dowhan W. 2001. Lack of mitochondrial anionic phospholipids causes an inhibition of translation of protein components of the electron transport chain. A yeast genetic model system for the study of anionic phospholipid function in mitochondria. J Biol Chem 276: 25 262-25 272.
49. Paradies G, Petrosillo G, Ruggiero FM. 1997. Cardiolipin-dependent decrease of cytochrome c oxidase activity in heart mitochondria from hypothyroid rats. Biochim Biophys Acta 1319: 5-8.
50. Perlman PS, Mahler HR. 1974. Derepression of mitochondria and their enzymes in yeast: regulatory aspects. Arch Biochem Biophys 162: 248-271.
51. Petrosillo G, Ruggiero FM, Di Venosa N, Paradies G. 2003. Decreased complex III activity in mitochondria isolated from rat heart subjected to ischemia and reperfusion: role of reactive oxygen species and cardiolipin. FASEB J 17: 714-716.
52. Robinson NC. 1993. Functional binding of cardiolipin to cytochrome c oxidase. J Bioenerg Biomembr 25: 153-163.
53. Robinson NC, Zborowski J, Talbert LH. 1990. Cardiolipin-depleted bovine heart cytochrome c oxidase: binding stoichiometry and affinity for cardiolipin derivatives. Biochemistry 29: 8962-8969.
54. Rusnak A, Mangat R, Xu F, McClarty G, Hatch GM. 1997. Cardiolipin remodeling in a Chinese hamster lung fibroblast cell line deficient in oxidative energy production. J Bioenerg Biomembr 29: 291-298.
55. Schwank S, Ebbert R, Rautenstrauss K, Schweizer E, Schuller HJ. 1995. Yeast transcriptional activator INO2 interacts as an Ino2p/Ino4p basic helix-loop-helix heteromeric complex with the inositol/choline-responsive element necessary for expression of phospholipid biosynthetic genes in Saccharomyces cerevisiae. Nucleic Acids Res 23: 230-237.
56. Shen H, Dowhan W. 1997. Regulation of phospholipid biosynthetic enzymes by the level of CDP-diacylglycerol synthase activity. J Biol Chem 272: 11 215-11 220.
57. Shen H, Dowhan W. 1998. Regulation of phosphatidylglycerophosphate synthase levels in Saccharomyces cerevisiae. J Biol Chem 273: 11 638-11 642.
58. Shen H, Heacock PN, Clancey CJ, Dowhan W. 1996. The CDS1 gene encoding CDP-diacylglycerol synthase in Saccharomyces cerevisiae is essential for cell growth. J Biol Chem 271: 789-795.
59. Shiao YJ, Lupo G, Vance JE. 1995. Evidence that phosphatidylserine is imported into mitochondria via a mitochondria-associated membrane and that the majority of mitochondrial phosphatidylethanolamine is derived from decarboxylation of phosphatidylserine. J Biol Chem 270: 11 190-11 198.
60. Sikorski RS, Hieter P. 1989. A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae. Genetics 122: 19-27.
61. Su X, Dowhan W. 2005. Translational regulation of nuclear gene COX4 expression by mitochondrial content of phosphatidylglycerol and cardiolipin in Saccharomyces cerevisiae. Mol Cell Biol (in press).
62. Tamai KT, Greenberg ML. 1990. Biochemical characterization and regulation of cardiolipin synthase in Saccharomyces cerevisiae. Biochim Biophys Acta 1046: 214-222.
63. Tuller G, Hrastnik C, Achleitner G, et al. 1998. YDL142c encodes cardiolipin synthase (Cls1p) and is non-essential for aerobic growth of Saccharomyces cerevisiae. FEBS Lett 421: 15-18.
64. Van Loon APGM, Van Eijk E, Grivell LA. 1983. Biosynthesis of the ubiquinol-cytochrome c reductase complex in yeast. Discoordinate synthesis of the 11 kDa subunit in response to increased gene copy number. EMBO J 2: 1765-1770.
65. Zhang M, Mileykovskaya E, Dowhan W. 2002. Gluing the respiratory chain together. Cardiolipin is required for supercomplex formation in the inner mitochondrial membrane. J Biol Chem 277: 43 553-43 556.
66. Zhang M, Mileykovskaya E, Dowhan W. 2005. Cardiolipin is essential for organization of complexes III and IV into a supercomplex in intact yeast mitochondria. J Biol Chem 280: 29 403-29 408.
67. Zhang M, Su X, Mileykovskaya E, Amoscato AA, Dowhan W. 2003. Cardiolipin is not required to maintain mitochondrial DNA stability or cell viability for Saccharomyces cerevisiae grown at elevated temperatures. J Biol Chem 278: 35 204-35 210.
68. Zhong Q, Gvozdenovic-Jeremic J, Webster P, Zhou J, Greenberg ML. 2005. Loss of function of KRE5 suppresses temperature sensitivity of mutants lacking mitochondrial anionic lipids. Mol Biol Cell 16: 665-675.