메뉴 건너뛰기




Volumn 107, Issue 2, 2009, Pages 233-239

HIF-1α regulates hypoxia-induced EP1 expression in osteoblastic cells

Author keywords

Ep1; HIF 1 ; Hypoxia; JNK; Osteoblast; SAPK

Indexed keywords

DIMETHYLOXALOGLYCINE; GLYCINE DERIVATIVE; HYPOXIA INDUCIBLE FACTOR 1; ISOPROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; OXYGEN; PROCOLLAGEN PROLINE 2 OXOGLUTARATE 4 DIOXYGENASE; PROCOLLAGEN PROLINE 2 OXOGLUTARATE 4 DIOXYGENASE 2; PROSTAGLANDIN E RECEPTOR; PROTEIN EP1; SMALL INTERFERING RNA; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG; EGLN1 PROTEIN, MOUSE; HIF1A PROTEIN, MOUSE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4; PROSTANOID RECEPTOR EP1;

EID: 66149088342     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.22119     Document Type: Article
Times cited : (16)

References (39)
  • 1
    • 0035104252 scopus 로고    scopus 로고
    • Hypoxia induces vascular endothelial growth factor gene transcription in human osteoblast-like cells through the hypoxia-inducible factor-2alpha
    • Akeno N, Czyzyk-Krzeska MF, Gross TS, Clemens TL. 2001. Hypoxia induces vascular endothelial growth factor gene transcription in human osteoblast-like cells through the hypoxia-inducible factor-2alpha. Endocrinology 142:959-962.
    • (2001) Endocrinology , vol.142 , pp. 959-962
    • Akeno, N.1    Czyzyk-Krzeska, M.F.2    Gross, T.S.3    Clemens, T.L.4
  • 2
    • 0015301667 scopus 로고
    • Oxygen tension of healing fractures in the rabbit
    • Brighton CT, Krebs AG. 1972. Oxygen tension of healing fractures in the rabbit. J Bone Joint Surg Am 54:323-332.
    • (1972) J Bone Joint Surg Am , vol.54 , pp. 323-332
    • Brighton, C.T.1    Krebs, A.G.2
  • 3
    • 70350523833 scopus 로고    scopus 로고
    • Cyclooxygenases and prostaglandin E2 receptors in growth plate chondrocytes in vitro and in situ - Prostaglandin E2 dependent proliferation of growth plate chondrocytes
    • Brochhausen C, Neuland P, Kirkpatrick CJ, Nusing RM, Klaus G. 2006. Cyclooxygenases and prostaglandin E2 receptors in growth plate chondrocytes in vitro and in situ - Prostaglandin E2 dependent proliferation of growth plate chondrocytes. Arthritis Res Ther 8:R78.
    • (2006) Arthritis Res Ther , vol.8
    • Brochhausen, C.1    Neuland, P.2    Kirkpatrick, C.J.3    Nusing, R.M.4    Klaus, G.5
  • 4
    • 0035834409 scopus 로고    scopus 로고
    • A conserved family of prolyl-4-hydroxylases that modify HIF
    • Bruick RK, McKnight SL. 2001. A conserved family of prolyl-4-hydroxylases that modify HIF. Science 294:1337-1340.
    • (2001) Science , vol.294 , pp. 1337-1340
    • Bruick, R.K.1    McKnight, S.L.2
  • 5
    • 0034920196 scopus 로고    scopus 로고
    • Hypoxia regulation of gene transcription
    • Caro J. 2001. Hypoxia regulation of gene transcription. High Alt Med Biol 2:145-154.
    • (2001) High Alt Med Biol , vol.2 , pp. 145-154
    • Caro, J.1
  • 6
    • 33846110857 scopus 로고    scopus 로고
    • Vitexin, an HIF-1alpha inhibitor, has anti-metastatic potential in PC12 cells
    • Choi HJ, Eun JS, Kim BG, Kim SY, Jeon H, Soh Y. 2006. Vitexin, an HIF-1alpha inhibitor, has anti-metastatic potential in PC12 cells. Mol Cells 22:291-299.
    • (2006) Mol Cells , vol.22 , pp. 291-299
    • Choi, H.J.1    Eun, J.S.2    Kim, B.G.3    Kim, S.Y.4    Jeon, H.5    Soh, Y.6
  • 7
    • 10844278331 scopus 로고    scopus 로고
    • 2-terminal kinase activation contributes to hypoxia-inducible factor 1alpha-dependent P-glycoprotein expression in hypoxia
    • DOI 10.1158/0008-5472.CAN-04-1919
    • Comerford KM, Cummins EP, Taylor CT. 2004. c-Jun NH2-terminal kinase activation contributes to hypoxia-inducible factor 1alpha-dependent P-glycoprotein expression in hypoxia. Cancer Res 64:9057-9061. (Pubitemid 39665517)
    • (2004) Cancer Research , vol.64 , Issue.24 , pp. 9057-9061
    • Comerford, K.M.1    Cummins, E.P.2    Taylor, C.T.3
  • 8
    • 0033551609 scopus 로고    scopus 로고
    • Selective activation of p38alpha and p38gamma by hypoxia. Role in regulation of cyclin D1 by hypoxia in PC12 cells
    • Conrad PW, Rust RT, Han J, Millhorn DE, Beitner-Johnson D. 1999. Selective activation of p38alpha and p38gamma by hypoxia. Role in regulation of cyclin D1 by hypoxia in PC12 cells. J Biol Chem 274:23570-23576.
    • (1999) J Biol Chem , vol.274 , pp. 23570-23576
    • Conrad, P.W.1    Rust, R.T.2    Han, J.3    Millhorn, D.E.4    Beitner-Johnson, D.5
  • 9
    • 0019514330 scopus 로고
    • Release of prostaglandins from bone and muscle after tibial fracture. An experimental study in rabbits
    • Dekel S, Lenthall G, Francis MJ. 1981. Release of prostaglandins from bone and muscle after tibial fracture. An experimental study in rabbits. J Bone Joint Surg Br 63-B:185-189.
    • (1981) J Bone Joint Surg Br , vol.63 B , pp. 185-189
    • Dekel, S.1    Lenthall, G.2    Francis, M.J.3
  • 10
    • 0032852497 scopus 로고    scopus 로고
    • Osteocyte hypoxia: A novel mechanotransduction pathway
    • Dodd JS, Raleigh JA, Gross TS. 1999. Osteocyte hypoxia: A novel mechanotransduction pathway. Am J Physiol 277:C598-C602.
    • (1999) Am J Physiol , vol.277
    • Dodd, J.S.1    Raleigh, J.A.2    Gross, T.S.3
  • 11
    • 50949109494 scopus 로고    scopus 로고
    • Pressure, oxygen tension and temperature in the periosteal callus during bone healing - An in vivo study in sheep
    • Epari DR, Lienau J, Schell H, Witt F, Duda GN. 2008. Pressure, oxygen tension and temperature in the periosteal callus during bone healing - an in vivo study in sheep. Bone 43:734-739.
    • (2008) Bone , vol.43 , pp. 734-739
    • Epari, D.R.1    Lienau, J.2    Schell, H.3    Witt, F.4    Duda, G.N.5
  • 13
    • 0141890273 scopus 로고    scopus 로고
    • Oxygen and iron regulation of iron regulatory protein 2
    • Hanson ES, Rawlins ML, Leibold EA. 2003. Oxygen and iron regulation of iron regulatory protein 2. J Biol Chem 278:40337-40342.
    • (2003) J Biol Chem , vol.278 , pp. 40337-40342
    • Hanson, E.S.1    Rawlins, M.L.2    Leibold, E.A.3
  • 14
    • 0043234538 scopus 로고    scopus 로고
    • Characterization of the human prolyl 4-hydroxylases that modify the hypoxia-inducible factor
    • Hirsila M, Koivunen P, Gunzler V, Kivirikko KI, Myllyharju J. 2003. Characterization of the human prolyl 4-hydroxylases that modify the hypoxia-inducible factor. J Biol Chem 278:30772-30780.
    • (2003) J Biol Chem , vol.278 , pp. 30772-30780
    • Hirsila, M.1    Koivunen, P.2    Gunzler, V.3    Kivirikko, K.I.4    Myllyharju, J.5
  • 15
    • 0029796904 scopus 로고    scopus 로고
    • Unifying theory of hypoxia tolerance: Molecular/metabolic defense and rescue mechanisms for surviving oxygen lack
    • Hochachka PW, Buck LT, Doll CJ, Land SC. 1996. Unifying theory of hypoxia tolerance: Molecular/metabolic defense and rescue mechanisms for surviving oxygen lack. Proc Natl Acad Sci USA 93:9493-9498.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 9493-9498
    • Hochachka, P.W.1    Buck, L.T.2    Doll, C.J.3    Land, S.C.4
  • 16
    • 33846566925 scopus 로고    scopus 로고
    • Prolyl-hydroxylase inhibition and HIF activation in osteoblasts promotes an adipocytic phenotype
    • Irwin R, LaPres JJ, Kinser S, McCabe LR. 2007. Prolyl-hydroxylase inhibition and HIF activation in osteoblasts promotes an adipocytic phenotype. J Cell Biochem 100:762-772.
    • (2007) J Cell Biochem , vol.100 , pp. 762-772
    • Irwin, R.1    Lapres, J.J.2    Kinser, S.3    McCabe, L.R.4
  • 18
    • 1642333512 scopus 로고    scopus 로고
    • Activation of the transcription factor HIF-1 and its target genes, VEGF, HO-1, iNOS, during fracture repair
    • Komatsu DE, Hadjiargyrou M. 2004. Activation of the transcription factor HIF-1 and its target genes, VEGF, HO-1, iNOS, during fracture repair. Bone 34:680-688.
    • (2004) Bone , vol.34 , pp. 680-688
    • Komatsu, D.E.1    Hadjiargyrou, M.2
  • 19
    • 0036837864 scopus 로고    scopus 로고
    • Regulation of protein synthesis by hypoxia via activation of the endoplasmic reticulum kinase PERK and phosphorylation of the translation initiation factor eIF2alpha
    • Koumenis C, Naczki C, Koritzinsky M, Rastani S, Diehl A, Sonenberg N, Koromilas A, Wouters BG. 2002. Regulation of protein synthesis by hypoxia via activation of the endoplasmic reticulum kinase PERK and phosphorylation of the translation initiation factor eIF2alpha. Mol Cell Biol 22:7405-7416.
    • (2002) Mol Cell Biol , vol.22 , pp. 7405-7416
    • Koumenis, C.1    Naczki, C.2    Koritzinsky, M.3    Rastani, S.4    Diehl, A.5    Sonenberg, N.6    Koromilas, A.7    Wouters, B.G.8
  • 20
    • 34249868225 scopus 로고    scopus 로고
    • Hypoxia regulates PGE(2) release and EP1 receptor expression in osteoblastic cells
    • Lee CM, Genetos DC, You Z, Yellowley CE. 2007. Hypoxia regulates PGE(2) release and EP1 receptor expression in osteoblastic cells. J Cell Physiol 212:182-188.
    • (2007) J Cell Physiol , vol.212 , pp. 182-188
    • Lee, C.M.1    Genetos, D.C.2    You, Z.3    Yellowley, C.E.4
  • 21
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method
    • Livak KJ, Schmittgen TD. 2001. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods 25:402-408.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 22
    • 0032547238 scopus 로고    scopus 로고
    • Proliferation and differentiation of human osteoblastic cells associated with differential activation of MAP kinases in response to epidermal growth factor, hypoxia, and mechanical stress in vitro
    • Matsuda N, Morita N, Matsuda K, Watanabe M. 1998. Proliferation and differentiation of human osteoblastic cells associated with differential activation of MAP kinases in response to epidermal growth factor, hypoxia, and mechanical stress in vitro. Biochem Biophys Res Commun 249:350-354.
    • (1998) Biochem Biophys Res Commun , vol.249 , pp. 350-354
    • Matsuda, N.1    Morita, N.2    Matsuda, K.3    Watanabe, M.4
  • 23
    • 0035478294 scopus 로고    scopus 로고
    • Transduction pathways involved in hypoxia-inducible factor-1 phosphorylation and activation
    • Minet E, Michel G, Mottet D, Raes M, Michiels C. 2001. Transduction pathways involved in hypoxia-inducible factor-1 phosphorylation and activation. Free Radic Biol Med 31:847-855.
    • (2001) Free Radic Biol Med , vol.31 , pp. 847-855
    • Minet, E.1    Michel, G.2    Mottet, D.3    Raes, M.4    Michiels, C.5
  • 24
    • 0034714265 scopus 로고    scopus 로고
    • Stress-activated protein kinases (JNK and p38/HOG) are essential for vascular endothelial growth factor mRNA stability
    • Pages G, Berra E, Milanini J, Levy AP, Pouyssegur J. 2000. Stress-activated protein kinases (JNK and p38/HOG) are essential for vascular endothelial growth factor mRNA stability. J Biol Chem 275:26484-26491.
    • (2000) J Biol Chem , vol.275 , pp. 26484-26491
    • Pages, G.1    Berra, E.2    Milanini, J.3    Levy, A.P.4    Pouyssegur, J.5
  • 25
    • 0022450587 scopus 로고
    • Regulation of protein metabolism of human cells during and after acute hypoxia
    • Pettersen EO, Juul NO, Ronning OW. 1986. Regulation of protein metabolism of human cells during and after acute hypoxia. Cancer Res 46:4346-4351.
    • (1986) Cancer Res , vol.46 , pp. 4346-4351
    • Pettersen, E.O.1    Juul, N.O.2    Ronning, O.W.3
  • 26
    • 0031037377 scopus 로고    scopus 로고
    • Regulation of tyrosine hydroxylase gene expression during hypoxia: Role of Ca2R and PKC
    • Raymond R, Millhorn D. 1997. Regulation of tyrosine hydroxylase gene expression during hypoxia: Role of Ca2R and PKC. Kidney Int 51:536-541.
    • (1997) Kidney Int , vol.51 , pp. 536-541
    • Raymond, R.1    Millhorn, D.2
  • 27
    • 0021345887 scopus 로고
    • Coordinate regulation of glycolysis by hypoxia in mammalian cells
    • Robin ED, Murphy BJ, Theodore J. 1984. Coordinate regulation of glycolysis by hypoxia in mammalian cells. J Cell Physiol 118:287-290.
    • (1984) J Cell Physiol , vol.118 , pp. 287-290
    • Robin, E.D.1    Murphy, B.J.2    Theodore, J.3
  • 28
    • 33744764250 scopus 로고    scopus 로고
    • Hypoxia and HIF-1alpha in chondrogenesis
    • Schipani E. 2006. Hypoxia and HIF-1alpha in chondrogenesis. Ann N Y Acad Sci 1068:66-73.
    • (2006) Ann N Y Acad Sci , vol.1068 , pp. 66-73
    • Schipani, E.1
  • 29
    • 0031590460 scopus 로고    scopus 로고
    • Hypoxia and hypoxia/reoxygenation activate p65PAK, p38 mitogen-activated protein kinase (MAPK), and stress-activated protein kinase (SAPK) in cultured rat cardiac myocytes
    • Seko Y, Takahashi N, Tobe K, Kadowaki T, Yazaki Y. 1997. Hypoxia and hypoxia/reoxygenation activate p65PAK, p38 mitogen-activated protein kinase (MAPK), and stress-activated protein kinase (SAPK) in cultured rat cardiac myocytes. Biochem Biophys Res Commun 239:840-844.
    • (1997) Biochem Biophys Res Commun , vol.239 , pp. 840-844
    • Seko, Y.1    Takahashi, N.2    Tobe, K.3    Kadowaki, T.4    Yazaki, Y.5
  • 30
    • 0030460724 scopus 로고    scopus 로고
    • Hypoxia response elements in the aldolase A, enolase 1, and lactate dehydrogenase a gene promoters contain essential binding sites for hypoxia-inducible factor 1
    • Semenza GL, Jiang BH, Leung SW, Passantino R, Concordet JP, Maire P, Giallongo A. 1996. Hypoxia response elements in the aldolase A, enolase 1, and lactate dehydrogenase A gene promoters contain essential binding sites for hypoxia-inducible factor 1. J Biol Chem 271:32529-32537.
    • (1996) J Biol Chem , vol.271 , pp. 32529-32537
    • Semenza, G.L.1    Jiang, B.H.2    Leung, S.W.3    Passantino, R.4    Concordet, J.P.5    Maire, P.6    Giallongo, A.7
  • 31
    • 0035999429 scopus 로고    scopus 로고
    • Cyclo-oxygenase 2 function is essential for bone fracture healing
    • Simon AM, Manigrasso MB, O'Connor JP. 2002. Cyclo-oxygenase 2 function is essential for bone fracture healing. J Bone Miner Res 17:963-976.
    • (2002) J Bone Miner Res , vol.17 , pp. 963-976
    • Simon, A.M.1    Manigrasso, M.B.2    O'Connor, J.P.3
  • 32
    • 0034282553 scopus 로고    scopus 로고
    • The Kaposi's sarcoma-associated herpes virus G protein-coupled receptor upregulates vascular endothelial growth factor expression and secretion through mitogen-activated protein kinase and p38 pathways acting on hypoxia-inducible factor 1alpha
    • Sodhi A, Montaner S, Patel V, Zohar M, Bais C, Mesri EA, Gutkind JS. 2000. The Kaposi's sarcoma-associated herpes virus G protein-coupled receptor upregulates vascular endothelial growth factor expression and secretion through mitogen-activated protein kinase and p38 pathways acting on hypoxia-inducible factor 1alpha. Cancer Res 60:4873-4880.
    • (2000) Cancer Res , vol.60 , pp. 4873-4880
    • Sodhi, A.1    Montaner, S.2    Patel, V.3    Zohar, M.4    Bais, C.5    Mesri, E.A.6    Gutkind, J.S.7
  • 34
    • 20744433675 scopus 로고    scopus 로고
    • 1 receptor, phospholipase C, protein kinase Calpha, and c-Src pathway in primary cultured rat osteoblasts
    • DOI 10.1074/jbc.M500130200
    • Tang CH, Yang RS, Fu WM. 2005. Prostaglandin E2 stimulates fibronectin expression through EP1 receptor, phospholipase C, protein kinase C alpha, and c-Src pathway in primary cultured rat osteoblasts. J Biol Chem 280:22907-22916. (Pubitemid 40853199)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.24 , pp. 22907-22916
    • Tang, C.-H.1    Yang, R.-S.2    Fu, W.-M.3
  • 35
    • 34249877724 scopus 로고    scopus 로고
    • Vascular biology and bone formation: Hints from HIF
    • Towler DA. 2007. Vascular biology and bone formation: Hints from HIF. J Clin Invest 117:1477-1480.
    • (2007) J Clin Invest , vol.117 , pp. 1477-1480
    • Towler, D.A.1
  • 36
    • 21644438244 scopus 로고    scopus 로고
    • SC-19220, antagonist of prostaglandin E2 receptor EP1, inhibits osteoclastogenesis by RANKL
    • Tsujisawa T, Inoue H, Nishihara T. 2005. SC-19220, antagonist of prostaglandin E2 receptor EP1, inhibits osteoclastogenesis by RANKL. J Bone Miner Res 20:15-22.
    • (2005) J Bone Miner Res , vol.20 , pp. 15-22
    • Tsujisawa, T.1    Inoue, H.2    Nishihara, T.3
  • 39
    • 0036259278 scopus 로고    scopus 로고
    • Cyclooxygenase-2 regulates mesenchymal cell differentiation into the osteoblast lineage and is critically involved in bone repair
    • Zhang X, Schwarz EM, Young DA, Puzas JE, Rosier RN, O'Keefe RJ. 2002. Cyclooxygenase-2 regulates mesenchymal cell differentiation into the osteoblast lineage and is critically involved in bone repair. J Clin Invest 109:1405-1415.
    • (2002) J Clin Invest , vol.109 , pp. 1405-1415
    • Zhang, X.1    Schwarz, E.M.2    Young, D.A.3    Puzas, J.E.4    Rosier, R.N.5    O'Keefe, R.J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.