-
1
-
-
33644974478
-
-
For selected papers, see: a
-
For selected papers, see: (a) Waterson, A. G.; Stevens, K. L.; Reno, M. J.; Zhang, Y.-M.; Boros, E. E.; Bouvier, F.; Rastagar, A.; Uehling, D. E.; Dickerson, S. H.; Reep, B.; McDonald, O. B.; Wood, E. R.; Rusnak, D. W.; Alligood, K. J.; Rudolph, S. K. Bioorg. Med. Chem. Lett. 2006, 16, 2419.
-
(2006)
Bioorg. Med. Chem. Lett
, vol.16
, pp. 2419
-
-
Waterson, A.G.1
Stevens, K.L.2
Reno, M.J.3
Zhang, Y.-M.4
Boros, E.E.5
Bouvier, F.6
Rastagar, A.7
Uehling, D.E.8
Dickerson, S.H.9
Reep, B.10
McDonald, O.B.11
Wood, E.R.12
Rusnak, D.W.13
Alligood, K.J.14
Rudolph, S.K.15
-
2
-
-
33746788115
-
-
(b) Atwal, K. S.; O'Neil, S. V.; Ahmad, S.; Doweyko, L.; Kirby, M.; Dorso, C. R.; Chandrasena, G.; Chen, B.-C.; Zhao, R.; Zahler, R. Bioorg. Med. Chem. Lett. 2006, 16, 4796.
-
(2006)
Bioorg. Med. Chem. Lett
, vol.16
, pp. 4796
-
-
Atwal, K.S.1
O'Neil, S.V.2
Ahmad, S.3
Doweyko, L.4
Kirby, M.5
Dorso, C.R.6
Chandrasena, G.7
Chen, B.-C.8
Zhao, R.9
Zahler, R.10
-
3
-
-
31544447715
-
-
(c) Alvarado, M.; Barcelo, M.; Carro, L.; Masaguer, C. F.; Ravina, E. Chem. Biodiversity 2006, 3, 106.
-
(2006)
Chem. Biodiversity
, vol.3
, pp. 106
-
-
Alvarado, M.1
Barcelo, M.2
Carro, L.3
Masaguer, C.F.4
Ravina, E.5
-
4
-
-
0347361705
-
-
(d) Buurman, E. T.; Blodgett, A. E.; Hull, K. G.; Carcanague, D. Antimicrob. Aeents Chemother. 2004, 48, 313.
-
(2004)
Antimicrob. Aeents Chemother
, vol.48
, pp. 313
-
-
Buurman, E.T.1
Blodgett, A.E.2
Hull, K.G.3
Carcanague, D.4
-
5
-
-
0030594967
-
-
Dickinson, R. P.; Bell, A. S.; Hitchcock, C. A.; Narayanaswami, S.; Ray, S. J.; Richardson, K.; Troke, P. F. Bioorg. Med. Chem. Lett. 1996, 6, 2031.
-
(1996)
Bioorg. Med. Chem. Lett
, vol.6
, pp. 2031
-
-
Dickinson, R.P.1
Bell, A.S.2
Hitchcock, C.A.3
Narayanaswami, S.4
Ray, S.J.5
Richardson, K.6
Troke, P.F.7
-
6
-
-
0031450416
-
-
Brodfuehrer, P. R.; Chen, B.-C.; Sattelberg, T. R., Sr.; Smith, P. R.; Reddy, J. P.; Stark, D. R.; Quinlan, S. L.; Reid, J. G.; Thottathil, J. K.; Wang, S. J. Org. Chem. 1997, 62, 9192.
-
(1997)
J. Org. Chem
, vol.62
, pp. 9192
-
-
Brodfuehrer, P.R.1
Chen, B.-C.2
Sattelberg Sr., T.R.3
Smith, P.R.4
Reddy, J.P.5
Stark, D.R.6
Quinlan, S.L.7
Reid, J.G.8
Thottathil, J.K.9
Wang, S.10
-
7
-
-
0037064479
-
-
For selected papers, see: a
-
For selected papers, see: (a) Zhang, Y.-M.; Razler, T.; Jackson, P. F. Tetrahedron Lett. 2002, 43, 8235.
-
(2002)
Tetrahedron Lett
, vol.43
, pp. 8235
-
-
Zhang, Y.-M.1
Razler, T.2
Jackson, P.F.3
-
8
-
-
0037041492
-
-
(b) Olivera, R.; SanMartin, R.; Tellitu, I.; Dominguez, E. Tetrahedron 2002, 58, 3021.
-
(2002)
Tetrahedron
, vol.58
, pp. 3021
-
-
Olivera, R.1
SanMartin, R.2
Tellitu, I.3
Dominguez, E.4
-
9
-
-
0031504362
-
-
(c) Rosso, V. W.; Lust, D. A.; Bernot, P. J.; Grosso, J. A.; Modi, S. P.; Rusowicz, A.; Sedergran, T. C.; Simpson, J. H.; Srivastava, S. K.; Humora, M. J.; Anderson, N. G. Org. Process Res. Dev. 1997, 1, 311.
-
(1997)
Org. Process Res. Dev
, vol.1
, pp. 311
-
-
Rosso, V.W.1
Lust, D.A.2
Bernot, P.J.3
Grosso, J.A.4
Modi, S.P.5
Rusowicz, A.6
Sedergran, T.C.7
Simpson, J.H.8
Srivastava, S.K.9
Humora, M.J.10
Anderson, N.G.11
-
10
-
-
0029080072
-
-
(d) Remuzon, P.; Dussy, C.; Jacquet, J. P.; Soumeillant, M.; Bouzard, D. Tetrahedron Lett. 1995, 36, 6227.
-
(1995)
Tetrahedron Lett
, vol.36
, pp. 6227
-
-
Remuzon, P.1
Dussy, C.2
Jacquet, J.P.3
Soumeillant, M.4
Bouzard, D.5
-
11
-
-
53849135238
-
-
For selected reviews on the preparation of pyrimidine derivatives, see: a
-
For selected reviews on the preparation of pyrimidine derivatives, see: (a) Hill, M. D.; Movassaghi, M. Chem.-Eur. J. 2008, 14, 6836.
-
(2008)
Chem.-Eur. J
, vol.14
, pp. 6836
-
-
Hill, M.D.1
Movassaghi, M.2
-
15
-
-
33750691360
-
-
For selected recent papers on the preparation of pyrimidine derivatives, see: a
-
For selected recent papers on the preparation of pyrimidine derivatives, see: (a) Movassaghi, M.; Hill, M. D. J. Am. Chem. Soc. 2006, 128, 14254.
-
(2006)
J. Am. Chem. Soc
, vol.128
, pp. 14254
-
-
Movassaghi, M.1
Hill, M.D.2
-
16
-
-
27544431953
-
-
Karpov, A. S.; Merkul, E.; Rominger, F.; Mueller, T. J. J. Ansew. Chem. Int. Ed. 2005, 44, 6951.
-
(b) Karpov, A. S.; Merkul, E.; Rominger, F.; Mueller, T. J. J. Ansew. Chem. Int. Ed. 2005, 44, 6951.
-
-
-
-
18
-
-
41149119445
-
-
(d) Blangetti, M.; Deagostino, A.; Prandi, C.; Zavattaro, C.; Venturello, P. Chem. Commun. 2008, 1689.
-
(2008)
Chem. Commun
, pp. 1689
-
-
Blangetti, M.1
Deagostino, A.2
Prandi, C.3
Zavattaro, C.4
Venturello, P.5
-
19
-
-
0037036710
-
-
(e) Kakiya, H.; Yagi, K.; Shinokubo, H.; Oshima, K. J. Am. Chem. Soc. 2002, 124, 9032.
-
(2002)
J. Am. Chem. Soc
, vol.124
, pp. 9032
-
-
Kakiya, H.1
Yagi, K.2
Shinokubo, H.3
Oshima, K.4
-
20
-
-
57749106138
-
-
(f) Heravi, M. M.; Sadjadi, S.; Oskooie, H. A.; Shoar, R. H.; Bamoharram, F. F. Tetrahedron Lett. 2009, 50, 662.
-
(2009)
Tetrahedron Lett
, vol.50
, pp. 662
-
-
Heravi, M.M.1
Sadjadi, S.2
Oskooie, H.A.3
Shoar, R.H.4
Bamoharram, F.F.5
-
22
-
-
33846592356
-
-
(h) Xie, F.; Li, S.; Bai, D.; Lou, L.; Hu, Y. J. Comb. Chem. 2007, 9, 12.
-
(2007)
J. Comb. Chem
, vol.9
, pp. 12
-
-
Xie, F.1
Li, S.2
Bai, D.3
Lou, L.4
Hu, Y.5
-
23
-
-
34047205297
-
-
(i) Kremsner, J. M.; Stadler, A.; Kappe, C. O. J. Comb. Chem. 2007, 9, 285.
-
(2007)
J. Comb. Chem
, vol.9
, pp. 285
-
-
Kremsner, J.M.1
Stadler, A.2
Kappe, C.O.3
-
26
-
-
0034729575
-
-
(l) Mueller, T. J. J.; Braun, R.; Ansorge, M. Org. Lett. 2000, 2, 1967.
-
(2000)
Org. Lett
, vol.2
, pp. 1967
-
-
Mueller, T.J.J.1
Braun, R.2
Ansorge, M.3
-
27
-
-
84981690823
-
-
For selected papers on the Bredereck-type synthesis of 4,5-disubstituted pyrimidines, see: (a) Bredereck, H.; Gompper, R.; Morlock, G. Chem, Ber. 1957, 90, 942.
-
For selected papers on the Bredereck-type synthesis of 4,5-disubstituted pyrimidines, see: (a) Bredereck, H.; Gompper, R.; Morlock, G. Chem, Ber. 1957, 90, 942.
-
-
-
-
30
-
-
33744481329
-
-
(d) Ingebrigtsen, T.; Helland, I.; Lejon, T. Heterocvles 2005, 65, 2593.
-
(2005)
Heterocvles
, vol.65
, pp. 2593
-
-
Ingebrigtsen, T.1
Helland, I.2
Lejon, T.3
-
31
-
-
66149096350
-
-
(e) Dominguez, E.; Martinez de Marigorta, E.; Olivera, R.; SanMartin, R. Svnlett 1995, 955.
-
(1995)
Svnlett
, pp. 955
-
-
Dominguez, E.1
Martinez de Marigorta, E.2
Olivera, R.3
SanMartin, R.4
-
32
-
-
0000190765
-
-
(f) Villa, M. J.; Dominguez, E.; Lete, E. Heterocvdes 1986, 24, 1943.
-
(1986)
Heterocvdes
, vol.24
, pp. 1943
-
-
Villa, M.J.1
Dominguez, E.2
Lete, E.3
-
33
-
-
85004464996
-
-
(g) Hirota, T.; Koyama, T.; Nanba, T.; Yamato, M.; Matsumura, T. Chem. Pharm. Bull. 1978, 26, 245.
-
(1978)
Chem. Pharm. Bull
, vol.26
, pp. 245
-
-
Hirota, T.1
Koyama, T.2
Nanba, T.3
Yamato, M.4
Matsumura, T.5
-
34
-
-
85008070320
-
-
(h) Koyama, T.; Hirota, T.; Bashou, C.; Satoh, Y.; Watanabe, Y.; Matsumoto, S.; Shinohara, Y.; Ohmori, S.; Yamato, M. Chem. Pharm. Bull. 1975, 23, 2158.
-
(1975)
Chem. Pharm. Bull
, vol.23
, pp. 2158
-
-
Koyama, T.1
Hirota, T.2
Bashou, C.3
Satoh, Y.4
Watanabe, Y.5
Matsumoto, S.6
Shinohara, Y.7
Ohmori, S.8
Yamato, M.9
-
37
-
-
84980107255
-
-
For selected papers on the Pinner-type synthesis of 4,5-disubstituted pyrimidines, see: (a) Pinner, A. Ber. 1893, 26, 2122.
-
For selected papers on the Pinner-type synthesis of 4,5-disubstituted pyrimidines, see: (a) Pinner, A. Ber. 1893, 26, 2122.
-
-
-
-
38
-
-
33947639605
-
-
(b) Baran, P. S.; Shenvi, R. A.; Nguyen, S. A. Heterocydes 2006, 70, 581.
-
(2006)
Heterocydes
, vol.70
, pp. 581
-
-
Baran, P.S.1
Shenvi, R.A.2
Nguyen, S.A.3
-
39
-
-
38749151312
-
-
(c) Cheng, G.; Li, S.; Li, J.; Hu, Y. Bioorg. Med. Chem. Lett. 2008, 18, 1177.
-
(2008)
Bioorg. Med. Chem. Lett
, vol.18
, pp. 1177
-
-
Cheng, G.1
Li, S.2
Li, J.3
Hu, Y.4
-
40
-
-
33750731631
-
-
(d) Winterwerber, M.; Geiger, R.; Otto, H.-H. Monatsh. Chem. 2006, 137, 1321.
-
(2006)
Monatsh. Chem
, vol.137
, pp. 1321
-
-
Winterwerber, M.1
Geiger, R.2
Otto, H.-H.3
-
41
-
-
33847328716
-
-
(e) Frasinyuk, M. S.; Bondarenko, S. P.; Khilya, V. P. Chem. Nat. Compd. 2006, 42, 673.
-
(2006)
Chem. Nat. Compd
, vol.42
, pp. 673
-
-
Frasinyuk, M.S.1
Bondarenko, S.P.2
Khilya, V.P.3
-
42
-
-
0003050111
-
-
(f) Funabiki, K.; Ohtsuki, T.; Ishihara, T.; Yamanaka, H. Chem. Lett. 1995, 239.
-
(1995)
Chem. Lett
, pp. 239
-
-
Funabiki, K.1
Ohtsuki, T.2
Ishihara, T.3
Yamanaka, H.4
-
43
-
-
0029149292
-
-
(g) Dinsmore, A.; Doyle, P. M.; Young, D. W. Tetrahedron Lett. 1995, 36, 7503.
-
(1995)
Tetrahedron Lett
, vol.36
, pp. 7503
-
-
Dinsmore, A.1
Doyle, P.M.2
Young, D.W.3
-
45
-
-
66149090069
-
-
For selected papers on the skeletal transformation to 4,5-disubstituted pyrimidines, see: a
-
For selected papers on the skeletal transformation to 4,5-disubstituted pyrimidines, see: (a) Nishiwaki, N.; Ariga, M. Top. Heterocycd. Chem. 2007, 8, 43.
-
(2007)
Top. Heterocycd. Chem
, vol.8
, pp. 43
-
-
Nishiwaki, N.1
Ariga, M.2
-
46
-
-
3242887941
-
-
(b) Nishiwaki, N.; Tamura, M.; Hori, K.; Tohda, Y.; Ariga, M. Molecules 2003, 8, 500.
-
(2003)
Molecules
, vol.8
, pp. 500
-
-
Nishiwaki, N.1
Tamura, M.2
Hori, K.3
Tohda, Y.4
Ariga, M.5
-
47
-
-
0037029811
-
-
(c) Bilbao, E. R.; Alvarado, M.; Masaguer, C. F.; Ravina, E. Tetrahedron Lett. 2002, 43, 3551.
-
(2002)
Tetrahedron Lett
, vol.43
, pp. 3551
-
-
Bilbao, E.R.1
Alvarado, M.2
Masaguer, C.F.3
Ravina, E.4
-
48
-
-
52549122309
-
-
(d) Nishiwaki, N.; Adachi, T.; Matsuo, K.; Wang, H.-P.; Matsunaga, T.; Tohda, Y.; Ariga, M. J. Chem. Soc. Perkin Trans. 1 2000, 27.
-
(2000)
J. Chem. Soc. Perkin Trans. 1
, pp. 27
-
-
Nishiwaki, N.1
Adachi, T.2
Matsuo, K.3
Wang, H.-P.4
Matsunaga, T.5
Tohda, Y.6
Ariga, M.7
-
49
-
-
0001153084
-
-
(e) Boger, D. L.; Schumacher, J.; Mullican, M. D.; Patel, M.; Panek, J. S. J. Org. Chem. 1982, 47, 2673.
-
(1982)
J. Org. Chem
, vol.47
, pp. 2673
-
-
Boger, D.L.1
Schumacher, J.2
Mullican, M.D.3
Patel, M.4
Panek, J.S.5
-
50
-
-
0001582362
-
-
(f) Huffman, K. R.; Schaefer, F. C.; Peters, G. A. J. Org. Chem. 1962, 27, 551.
-
(1962)
J. Org. Chem
, vol.27
, pp. 551
-
-
Huffman, K.R.1
Schaefer, F.C.2
Peters, G.A.3
-
51
-
-
0034731545
-
-
For selected papers on the functional group transformation to 4,5-disubstituted pyrimidines, see: a
-
For selected papers on the functional group transformation to 4,5-disubstituted pyrimidines, see: (a) Sard, H.; Gonzalez, M. D.; Mahadevan, A.; McKew, J. J. Org. Chem. 2000, 65, 9261.
-
(2000)
J. Org. Chem
, vol.65
, pp. 9261
-
-
Sard, H.1
Gonzalez, M.D.2
Mahadevan, A.3
McKew, J.4
-
52
-
-
48849106615
-
-
(b) Boudet, N.; Dubbaka, S. R.; Knochel, P. Org. Lett. 2008, 10, 1715.
-
(2008)
Org. Lett
, vol.10
, pp. 1715
-
-
Boudet, N.1
Dubbaka, S.R.2
Knochel, P.3
-
54
-
-
37049078654
-
-
(d) Togo, H.; Ishigami, S.; Fujii, M.; Ikuma, T.; Yokoyama, M. J. Chem. Soc. Perkin Trans. 1 1994, 2931.
-
(1994)
J. Chem. Soc. Perkin Trans. 1
, pp. 2931
-
-
Togo, H.1
Ishigami, S.2
Fujii, M.3
Ikuma, T.4
Yokoyama, M.5
-
56
-
-
0003953077
-
-
(f) Yamanaka, H.; Sakamoto, T.; Nishimura, S.; Sagi, M. Chem. Pharm. Bull. 1987, 35, 3119.
-
(1987)
Chem. Pharm. Bull
, vol.35
, pp. 3119
-
-
Yamanaka, H.1
Sakamoto, T.2
Nishimura, S.3
Sagi, M.4
-
59
-
-
2942585558
-
-
Mangelinckx, S.; Giubellina, N.; De Kimpe, N. Chem. Rev. 2004, 104, 2353.
-
(2004)
Chem. Rev
, vol.104
, pp. 2353
-
-
Mangelinckx, S.1
Giubellina, N.2
De Kimpe, N.3
-
60
-
-
51549097124
-
-
(a) Sasada, T.; Sakai, N.; Konakahara, T. J. Org. Chem. 2008, 73, 6905.
-
(2008)
J. Org. Chem
, vol.73
, pp. 6905
-
-
Sasada, T.1
Sakai, N.2
Konakahara, T.3
-
61
-
-
27144464021
-
-
(b) Sakai, N.; Aoki, Y.; Sasada, T.; Konakahara, T. Org. Lett. 2005, 7, 4705.
-
(2005)
Org. Lett
, vol.7
, pp. 4705
-
-
Sakai, N.1
Aoki, Y.2
Sasada, T.3
Konakahara, T.4
-
62
-
-
34547096469
-
-
(c) Suzuki, H.; Sakai, N.; Iwahara, R.; Fujiwaka, T.; Satoh, M.; Kakehi, A.; Konakahara, T. J. Org. Chem. 2007, 72, 5878.
-
(2007)
J. Org. Chem
, vol.72
, pp. 5878
-
-
Suzuki, H.1
Sakai, N.2
Iwahara, R.3
Fujiwaka, T.4
Satoh, M.5
Kakehi, A.6
Konakahara, T.7
-
63
-
-
30944437838
-
-
(d) Sakai, N.; Aoki, D.; Hamajima, T.; Konakahara, T. Tetrahedron Lett. 2006, 47, 1261.
-
(2006)
Tetrahedron Lett
, vol.47
, pp. 1261
-
-
Sakai, N.1
Aoki, D.2
Hamajima, T.3
Konakahara, T.4
-
64
-
-
30944449133
-
-
(e) Sakai, N.; Hattori, N.; Tomizawa, N.; Abe, N.; Konakahara, T. Heterocvdes 2005, 65, 2799.
-
(2005)
Heterocvdes
, vol.65
, pp. 2799
-
-
Sakai, N.1
Hattori, N.2
Tomizawa, N.3
Abe, N.4
Konakahara, T.5
|