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Volumn 6, Issue 16, 1996, Pages 2031-2036

Novel antifungal 2-aryl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol derivatives with high activity against Aspergillus fumigatus

Author keywords

[No Author keywords available]

Indexed keywords

1,2,4 TRIAZOLE DERIVATIVE; ANTIFUNGAL AGENT; VORICONAZOLE;

EID: 0030594967     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/0960-894X(96)00363-0     Document Type: Article
Times cited : (98)

References (19)
  • 5
    • 0011723334 scopus 로고
    • (4) Narayanaswami, S.; Richardson, K. Eur. Pat. 122,056; Chem. Astr. 1985, 102, 132,042.
    • (1985) Chem. Astr. , vol.102 , pp. 132
  • 7
    • 85030269761 scopus 로고    scopus 로고
    • UK Pat. 2,099,818,1982
    • (6) Richardson, K. UK Pat. 2,099,818,1982; Chem. Abstr. 1983, 99, 38467.
    • Richardson, K.1
  • 8
    • 4243847727 scopus 로고
    • (6) Richardson, K. UK Pat. 2,099,818,1982; Chem. Abstr. 1983, 99, 38467.
    • (1983) Chem. Abstr. , vol.99 , pp. 38467
  • 9
    • 85030278248 scopus 로고    scopus 로고
    • note
    • (7) For evaluation of compounds in vitro, a series of agar plates, or liquid medium in microtiter plates, each having the test compound incorporated at a particular concentration, was inoculated with a standard culture of fungus, e.g. A. fumigatus, and each plate was then incubated for 48 hr. at 37°C. The plates were then examined for the presence or absence of growth of the fungus and the appropriate MIC was noted.
  • 10
    • 85030274063 scopus 로고    scopus 로고
    • Detailed X-ray crystallographic data for 24b and 30 have been deposited at the Cambridge Cristallographic Data Centre
    • (8) Detailed X-ray crystallographic data for 24b and 30 have been deposited at the Cambridge Cristallographic Data Centre.
  • 13
    • 85030278492 scopus 로고    scopus 로고
    • 25 -62° (c = 1mg/ml in MeOH)
    • 25 -62° (c = 1mg/ml in MeOH)


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.