Mice deficient in ribosomal protein S6 phosphorylation suffer from muscle weakness that reflects a growth defect and energy deficit

PLoS ONE

Volumn 4, Issue 5, 2009, Pages

  Ruvinsky, Igor ^a,d   Katz, Maximiliano ^a,e   Dreazen, Avigail ^a   Gielchinsky, Yuval ^b   Saada, Ann ^b   Freedman, Nanette ^b   Mishani, Eyal ^b   Zimmerman, Gabriel ^c   Kasir, Judith ^a   Meyuhas, Oded ^a  

^a HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^b HADASSAH HEBREW UNIVERSITY MEDICAL CENTER   (Israel)

^c HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^d Novamed Ltd   (Israel)

^e FUNDACIÓN INSTITUTO LELOIR   (Argentina)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; CONTRACTILE PROTEIN; CREATINE PHOSPHATE; GLUCOSE; GLYCOGEN; INSULIN; MITOCHONDRIAL PROTEIN; PROTEIN S6; TRIACYLGLYCEROL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; ENERGY METABOLISM; ENZYME ACTIVITY; GENOTYPE; GLUCOSE TRANSPORT; GROWTH RETARDATION; HISTOPATHOLOGY; LIPID DEGRADATION; MALE; MORPHOMETRICS; MOUSE; MUSCLE CELL; MUSCLE MASS; MUSCLE STRENGTH; MUSCLE WEAKNESS; NONHUMAN; OXIDATIVE PHOSPHORYLATION; PATHOGENESIS; POSITRON EMISSION TOMOGRAPHY; PROTEIN DEFICIENCY; PROTEIN PHOSPHORYLATION; PROTEOMICS; ANIMAL; DRUG EFFECT; GROWTH, DEVELOPMENT AND AGING; METABOLISM; MITOCHONDRION; MUSCLE CONTRACTION; ORGAN SIZE; SIGNAL TRANSDUCTION; SKELETAL MUSCLE;

MUS;

ADENOSINE TRIPHOSPHATE; ANIMALS; ENERGY METABOLISM; GLUCOSE; GLYCOGEN; INSULIN; MICE; MITOCHONDRIA; MUSCLE CONTRACTION; MUSCLE FIBERS, SKELETAL; MUSCLE WEAKNESS; MUSCLE, SKELETAL; ORGAN SIZE; OXIDATIVE PHOSPHORYLATION; PHOSPHOCREATINE; RIBOSOMAL PROTEIN S6; SIGNAL TRANSDUCTION; TRIGLYCERIDES;

EID: 66049157014     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0005618     Document Type: Article

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