Role of plasmacytoid dendritic cells for aberrant class II expression in exocrine glands from estrogen-deficient mice of healthy background

American Journal of Pathology

Volumn 174, Issue 5, 2009, Pages 1715-1724

  Arakaki, Rieko ^a   Nagaoka, Ai ^a   Ishimaru, Naozumi ^a   Yamada, Akiko ^a   Yoshida, Satoko ^a   Hayashi, Yoshio ^a  

^a UNIVERSITY OF TOKUSHIMA   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

INTERFERON REGULATORY FACTOR 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; ESTROGEN; GAMMA INTERFERON; HLA ANTIGEN CLASS 2; MESSENGER RNA; MHC CLASS II TRANSACTIVATOR PROTEIN; NUCLEAR PROTEIN; TRANSACTIVATOR PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOIMMUNE DISEASE; CONTROLLED STUDY; DENDRITIC CELL; EPITHELIUM CELL; ESTROGEN DEFICIENCY; EXOCRINE GLAND; FEMALE; MOUSE; NONHUMAN; OVARIECTOMY; PLASMA CELL; POSTMENOPAUSE; PRIORITY JOURNAL; SALIVA; SALIVARY GLAND; ANIMAL; ANTIGEN PRESENTING CELL; C57BL MOUSE; CELL CULTURE; CELL PROLIFERATION; CYTOLOGY; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; GENETICS; IMMUNOLOGY; METABOLISM; NICK END LABELING; PATHOLOGY; PHYSIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; T LYMPHOCYTE; TRANSGENIC MOUSE;

ANIMALS; ANTIGEN-PRESENTING CELLS; CELL PROLIFERATION; CELLS, CULTURED; DENDRITIC CELLS; ENZYME-LINKED IMMUNOSORBENT ASSAY; EPITHELIAL CELLS; ESTROGENS; FEMALE; FLOW CYTOMETRY; HISTOCOMPATIBILITY ANTIGENS CLASS II; IN SITU NICK-END LABELING; INTERFERON REGULATORY FACTOR-1; INTERFERON-GAMMA; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; NUCLEAR PROTEINS; OVARIECTOMY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SALIVARY GLANDS; T-LYMPHOCYTES; TRANS-ACTIVATORS;

EID: 65649129340     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.2353/ajpath.2009.080695     Document Type: Article

References (45)

1. Jones EY, Fugger L, Strominger JL, Siebold C: MHC class II proteins and disease: a structural perspective. Nat Rev Immunol 2006, 4:271-282
2. Nicholson MJ, Hahn M, Wucherpfennig KW: Unusual features of self-peptide/MHC binding by autoimmune T cell receptors. Immunity 2005, 23:351-360 (Pubitemid 41443437)
3. Watts C: The exogenous pathway for antigen presentation on major histocompatibility complex class II and CD1 molecules. Nat Immunol 2004, 7:685-692 (Pubitemid 39023297)
4. Müller-Hilke B, Mitchison NA: The role of HLA promoters in autoimmunity. Curr Pharm Des 2006, 12:3743-3752 (Pubitemid 44565990)
5. Mandik-Nayak L, Allen PM: Initiation of an autoimmune response: insights from a transgenic model of rheumatoid arthritis. Immunol Res 2005, 32:5-13 (Pubitemid 41153610)
6. Nepom GT, Kwok WW: Molecular basis for HLA-DQ associations with IDDM. Diabetes 1998, 47:1177-1184 (Pubitemid 28356991)
7. Caturegli P, Kimura H, Rocchi R, Rose NR: Autoimmune thyroid diseases. Curr Opin Rheumatol 2007, 19:44-48
8. g7 MHC class II molecule linked to murine diabetes is a promiscuous peptide binder. J Immunol 2000, 165:3214-3225
9. van der Helm-van Mil AH, Wesoly JZ, Huizinga TW: Understanding the genetic contribution to rheumatoid arthritis. Curr Opin Rheumatol 2005, 17:299-304 (Pubitemid 40616576)
10. Fox RI, Stem M, Michelson P: Update in Sjogren's syndrome. Curr Opin Rheumatol 2000, 12:391-398
11. Loureiro J, Ploegh HL: Antigen presentation and the ubiquitin-proteasome system in host-pathogen interactions. Adv Immunol 2006, 92:225-305
12. Londei M, Lamb JR, Bottazzo G: F. Feldmann M Epithelial cell expressing aberrant MHC class II determinants can present antigen to cloned human T cells. Nature 1984, 312:639-641
13. u. Immunity 2002, 17:83-94
14. Renauld JC: Class II cytokine receptors and their ligands: key antiviral and inflammatory modulators. Nat Rev Immunol 2003, 3:667-676 (Pubitemid 37328669)
15. Liu YJ, Kanzler H, Soumelis V, Gilliet M: Dendritic cell lineage, plasticity and cross-regulation. Nat Immunol 2001, 2:585-1289 (Pubitemid 32677624)
16. Friese MA, Jones EY, Fugger L: MHC II molecules in inflammatory diseases: interplay of qualities and quantities. Trends Immunol 2005, 26:559-561 (Pubitemid 41726441)
17. Chang CH, Gourley TS, Sisk TJ: Function and regulation of class II transactivator in the immune system. Immunol Res 2002, 25:131-142 (Pubitemid 34264099)
18. Ting JP, Trowsdale J. Genetic control of MHC class II expression. Cell 2002, 109 Suppl:S21-S33
19. Wright KL, Ting JP: Epigenetic regulation of MHC-II and CIITA genes. Trends Immunol 2006, 27:405-412 (Pubitemid 44216195)
20. Nalbandian G, Kovats S: Understanding sex biases in immunity: effects of estrogen on the differentiation and function of antigen-presenting cells. Immunol Res 2005, 31:91-106 (Pubitemid 40631381)
21. Gourdy P, Araujo LM, Zhu R, Garmy-Susini B, Diem S, Laurell H, Leite-de-Moraes M, Dy M, Arnal JF, Bayard F, Herbelin A: Relevance of sexual dimorphism to regulatory T cells: estradiol promotes IFN-γ production by invariant natural killer T cells. Blood 2005, 105:2415-2420 (Pubitemid 40387040)
22. Mo R, Chen J, Grolleau-Julius A, Murphy HS, Richardson BC, Yung RL: Estrogen regulates CCR gene expression and function in T lymphocytes. J Immunol 2005, 174:6023-6029 (Pubitemid 40663789)
23. Soucy G, Boivin G, Labrie F, Rivest S: Estradiol is required for a proper immune response to bacterial and viral pathogens in the female brain. J Immunol 2005, 174:6391-6398 (Pubitemid 40663832)
24. Polanczyk MJ, Carson BD, Subramanian S, Afentoulis M, Vandenbark AA, Ziegler SF, Offner H: Estrogen drives expansion of the CD4+CD25+ regulatory T cell compartment. J Immunol 2004, 173:2227-2230
25. Whitacre CC: Sex differences in autoimmune disease. Nat Immunol 2001, 2:777-780
26. Whitacre CC, Reingold SC, O'Looney PA: A gender gap in autoimmunity. Science 1999, 283:1277-1278 (Pubitemid 129507205)
27. Ishimaru N, Saegusa K, Yanagi K, Haneji N, Saito I, Hayashi Y: Estrogen deficiency accelerates autoimmune exocrinopathy in murine Sjogren's syndrome through Fas-mediated apoptosis. Am J Pathol 1999, 155:173-181 (Pubitemid 29318715)
28. Ishimaru N, Arakaki R, Watanabe M, Kobayashi M, Miyazaki K, Hayashi Y: Development of autoimmune exocrinopathy resembling Sjogren's syndrome in estrogen deficient mice of healthy background. Am J Pathol 2003, 163:1481-1490 (Pubitemid 37175095)
29. Gottenberg J-E, Cagnard N, Lucchesi C, Letourneur F, Mituou S, Lazure T, Jacques S, Ba N, Ittah M, Lwpajolec C, Labetoulle M, Ardizzone M, Sibilia J, Fournier C, Chiocchia G., Mariette X. 2006. Activation of IFN pathways and plasmacytoid dendritic cell recruitment in target organs of primary Sjogren's syndrome. Proc Natl Acad Sci USA 2006, 103:2770-2775
30. Robertson JM, Jensen PE, Evavold BD: DO11.10 and OT-II T cells recognize a C-terminal ovalbumin 323-339 epitope. J Immunol 2000, 164:4706-4712 (Pubitemid 30238071)
31. Steimle V, Siegrist CA, Mottet A, Lisowska-Grospierre B, Mach B: Regulation of MHC class II expression by interferon-γ mediated by the transactivator gene CIITA. Science 1994, 265:106-109 (Pubitemid 24253184)
32. Harton JA, Ting JP: Class II transactivator: mastering the art of major histocompatibility complex expression. Mol Cell Biol 2000, 20:6185-6194 (Pubitemid 30650205)
33. Barbieri G, Deffrennes V, Prod'homme T, Vedrenne J, Baton F, Cortes C, Fischer A, Bono MR, Lisowska-Grospierre B, Charron D, Alcaïde-Loridan C: Isoforms of the class II transactivator protein. Int Immunol 2002, 14:839-848
34. Piskurich JF, Linhoff MW, Wang Y, Ting JP: Two distinct gamma interferon-inducible promoters of the major histocompatibility complex class II transactivator gene are differentially regulated by STAT1, interferon regulatory factor 1, and transforming growth factor beta. Mol Cell Biol 1999, 19:431-440 (Pubitemid 29018445)
35. Bouker KB, Skaar TC, Fernandez DR, O'Brien KA, Riggins RB, Cao D, Clarke R: Interferon regulatory factor-1 mediates the proapoptotic but not cell cycle arrest effects of the steroidal antiestrogen ICI 182,780 (Faslodex, Fulvestrant). Cancer Res 2004, 64:4030-4039 (Pubitemid 38701758)
36. Zika E, Ting JP: Epigenetic control of MHC-II: interplay between CIITA and histone-modifying enzymes. Curr Opin Immunol 2005, 17:58-64 (Pubitemid 40094015)
37. Orbach H, Shoenfeld Y: Hyperprolactinemia and autoimmune diseases. Autoimmu Rev 2007, 6:537-542 (Pubitemid 47374609)
38. Porola P, Laine M, Virkki L, Poduval P, Konttinen YT: The influence of sex steroids on Sjogren's syndrome. Ann NY Acad Sci 2007, 1108:426-432 (Pubitemid 47528756)
39. Kanazawa S, Ota S, Sekine C, Tada T, Otsuka T, Okamoto T, Sonderstrup G, Peterlin BM: Aberrant MHC class II expression in mouse joints leads to arthritis with extraarticular manifestations similar to rheumatoid arthritis. Proc Natl Acad Sci USA 2006, 103:14465-14470 (Pubitemid 44484773)
40. Kimura H, Kimura M, Tzou SC, Chen YC, Suzuki K, Rose NR, Catureqli P: Expression of class II major histocompatibility complex molecules on thyrocytes does not cause spontaneous thyroiditis but mildly increases its severity after immunization. Endocrinol 2005, 146:1154-1162 (Pubitemid 40289304)
41. Panek RB, Lee YJ, Itoh-Lindstrom Y, Ting JP, Benveniste EN: Characterization of astrocyte nuclear proteins involved in IFN-γ-and TNF-α-mediated class II MHC gene expression. J Immunol 1994, 153:4555-4564 (Pubitemid 24346850)
42. Soos JM, Morrow J, Ashley TA, Szente BE, Bikoff EK, Zamvil SS: Astrocytes express elements of the class II endocytic pathway and process central nervous system autoantigen for presentation to encephalitogenic T cells. J Immunol 1998, 161:5959-5966 (Pubitemid 28535964)
43. Legge KL, Gregg RK, Maldonado-Lopez R, Li L, Caprio JC, Moser M, Zaghouani H: On the role of dendritic cells in peripheral T cell tolerance and modulation of autoimmunity. J Exp Med 2002, 196:217-227
44. Thomas R, Davis LS, Lipsky PE: Rheumatoid synovium is enriched in mature antigen-presenting dendritic cells. J Immunol 1994, 152:2613-2623 (Pubitemid 24097956)
45. Menges M, Rossner S, Voigtlander C, Schindler H, Kukutsch NA, Bogdan C, Erb K, Schuler G, Lutz MB: Repetitive injections of dendritic cells matured with tumor necrosis factor α induce antigen-specific protection of mice from autoimmunity. J Exp Med 2002, 195:15-21 (Pubitemid 34074492)