메뉴 건너뛰기




Volumn 109, Issue 4, 2009, Pages 981-994

Interaction of catechol and non-catechol substrates with externally or internally facing dopamine transporters

Author keywords

Binding sidedness; Catechol substrates; Digitonin; Dopamine transporter; Dopamine transporter conformations

Indexed keywords

1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; ADRENALIN; CATECHOL; COCAINE; DEXAMPHETAMINE; DIGITONIN; DOPAMINE TRANSPORTER; NORADRENALIN; PHENETHYLAMINE; TYRAMINE;

EID: 65649098434     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2009.06034.x     Document Type: Article
Times cited : (26)

References (60)
  • 1
    • 0032104581 scopus 로고    scopus 로고
    • Neurotransmitter transporters as molecular targets for addictive drugs
    • DOI 10.1016/S0376-8716(98)00068-4, PII S0376871698000684
    • Amara S. G. Sonders M. S. (1998) Neurotransmitter transporters as molecular targets for addictive drugs. Drug Alcohol Depend. 51, 87 96. (Pubitemid 28353758)
    • (1998) Drug and Alcohol Dependence , vol.51 , Issue.1-2 , pp. 87-96
    • Amara, S.G.1    Sonders, M.S.2
  • 2
    • 0026567794 scopus 로고
    • Kinetic analysis of the chloride dependence of the neuronal uptake of dopamine and effect of anions on the ability of substrates to compete with the binding of the dopamine uptake inhibitor GBR
    • 12783.
    • Amejdki-Chab N., Costentin J. Bonnet J. J. (1992) Kinetic analysis of the chloride dependence of the neuronal uptake of dopamine and effect of anions on the ability of substrates to compete with the binding of the dopamine uptake inhibitor GBR 12783. J. Neurochem. 58, 793 800.
    • (1992) J. Neurochem. , vol.58 , pp. 793-800
    • Amejdki-Chab, N.1    Costentin, J.2    Bonnet, J.J.3
  • 3
    • 0036812497 scopus 로고    scopus 로고
    • Accessibility and conformational coupling in serotonin transporter predicted internal domains
    • Androutsellis-Theotokis A. Rudnick G. (2002) Accessibility and conformational coupling in serotonin transporter predicted internal domains. J. Neurosci. 22, 8370 8378. (Pubitemid 35387577)
    • (2002) Journal of Neuroscience , vol.22 , Issue.19 , pp. 8370-8378
    • Androutsellis-Theotokis, A.1    Rudnick, G.2
  • 4
    • 1642457228 scopus 로고    scopus 로고
    • Structure-activity relationships for substrate recognition by the human dopamine transporter
    • DOI 10.1016/j.bcp.2003.09.013
    • Appell M., Berfield J. L., Wang L. C., Dunn III. W. J., Chen N. Reith M. E. (2004) Structure-activity relationships for substrate recognition by the human dopamine transporter. Biochem. Pharmacol. 67, 293 302. (Pubitemid 38112760)
    • (2004) Biochemical Pharmacology , vol.67 , Issue.2 , pp. 293-302
    • Appell, M.1    Berfield, J.L.2    Wang, L.C.3    Dunn III, W.J.4    Chen, N.5    Reith, M.E.A.6
  • 5
    • 17444395169 scopus 로고    scopus 로고
    • The dopamine transporter: Role in neurotoxicity and human disease
    • DOI 10.1016/j.taap.2004.08.013, Membrane Transporters in Toxicology
    • Bannon M. J. (2005) The dopamine transporter: role in neurotoxicity and human disease. Toxicol. Appl. Pharmacol. 204, 355 360. (Pubitemid 40545237)
    • (2005) Toxicology and Applied Pharmacology , vol.204 , Issue.3 , pp. 355-360
    • Bannon, M.J.1
  • 6
    • 33751194447 scopus 로고    scopus 로고
    • A comprehensive structure-based alignment of prokaryotic and eukaryotic neurotransmitter/Na+ symporters (NSS) aids in the use of the LeuT structure to probe NSS structure and function
    • Beuming T., Shi L., Javitch J. A. Weinstein H. (2006) A comprehensive structure-based alignment of prokaryotic and eukaryotic neurotransmitter/Na+ symporters (NSS) aids in the use of the LeuT structure to probe NSS structure and function. Mol. Pharmacol. 70, 1630 1642.
    • (2006) Mol. Pharmacol. , vol.70 , pp. 1630-1642
    • Beuming, T.1    Shi, L.2    Javitch, J.A.3    Weinstein, H.4
  • 7
    • 46049086729 scopus 로고    scopus 로고
    • The binding sites for cocaine and dopamine in the dopamine transporter overlap
    • Beuming T., Kniazeff J., Bergmann M. L. et al. (2008) The binding sites for cocaine and dopamine in the dopamine transporter overlap. Nat. Neurosci. 11, 780 789.
    • (2008) Nat. Neurosci. , vol.11 , pp. 780-789
    • Beuming, T.1    Kniazeff, J.2    Bergmann, M.L.3
  • 9
    • 52049099133 scopus 로고    scopus 로고
    • Dopamine transporter endocytic determinants: Carboxy terminal residues critical for basal and PKC-stimulated internalization
    • Boudanova E., Navaroli D. M., Stevens Z. Melikian H. E. (2008) Dopamine transporter endocytic determinants: carboxy terminal residues critical for basal and PKC-stimulated internalization. Mol. Cell. Neurosci. 39, 211 217.
    • (2008) Mol. Cell. Neurosci. , vol.39 , pp. 211-217
    • Boudanova, E.1    Navaroli, D.M.2    Stevens, Z.3    Melikian, H.E.4
  • 11
    • 0033694833 scopus 로고    scopus 로고
    • From ionic currents to molecular mechanisms: The structure and function of voltage-gated sodium channels
    • Catterall W. A. (2000) From ionic currents to molecular mechanisms: the structure and function of voltage-gated sodium channels. Neuron 26, 13 25.
    • (2000) Neuron , vol.26 , pp. 13-25
    • Catterall, W.A.1
  • 12
    • 0032535582 scopus 로고    scopus 로고
    • Cocaine acts as an apparent competitive inhibitor at the outward-facing conformation of the human norepinephrine transporter: Kinetic analysis of inward and outward transport
    • Chen N. Justice Jr. J. B. (1998) Cocaine acts as an apparent competitive inhibitor at the outward-facing conformation of the human norepinephrine transporter: kinetic analysis of inward and outward transport. J. Neurosci. 18, 10257 10268. (Pubitemid 29016545)
    • (1998) Journal of Neuroscience , vol.18 , Issue.24 , pp. 10257-10268
    • Chen, N.1    Justice Jr., J.B.2
  • 13
    • 0033970317 scopus 로고    scopus 로고
    • Differential effect of structural modification of human dopamine transporter on the inward and outward transport of dopamine
    • DOI 10.1016/S0169-328X(99)00288-0, PII S0169328X99002880
    • Chen N. Justice J. B. (2000) Differential effect of structural modification of human dopamine transporter on the inward and outward transport of dopamine. Brain Res. Mol. Brain Res. 75, 208 215. (Pubitemid 30109271)
    • (2000) Molecular Brain Research , vol.75 , Issue.2 , pp. 208-215
    • Chen, N.1    Justice Jr., J.B.2
  • 14
    • 2042450810 scopus 로고    scopus 로고
    • Interaction between dopamine and its transporter: Role of intracellular sodium ions and membrane potential
    • Chen N. Reith M. E. (2004) Interaction between dopamine and its transporter: role of intracellular sodium ions and membrane potential. J. Neurochem. 89, 750 765. (Pubitemid 38534160)
    • (2004) Journal of Neurochemistry , vol.89 , Issue.3 , pp. 750-765
    • Chen, N.1    Reith, M.E.A.2
  • 15
    • 0035020831 scopus 로고    scopus 로고
    • The role of conserved tryptophan and acidic residues in the human dopamine transporter as characterized by site-directed mutagenesis
    • DOI 10.1046/j.1471-4159.2001.00312.x
    • Chen N., Vaughan R. A. Reith M. E. (2001) The role of conserved tryptophan and acidic residues in the human dopamine transporter as characterized by site-directed mutagenesis. J. Neurochem. 77, 1116 1127. (Pubitemid 32467066)
    • (2001) Journal of Neurochemistry , vol.77 , Issue.4 , pp. 1116-1127
    • Chen, N.1    Vaughan, R.A.2    Reith, M.E.A.3
  • 16
    • 0036312480 scopus 로고    scopus 로고
    • Cationic interactions at the human dopamine transporter reveal binding conformations for dopamine distinguishable from those for the cocaine analog 2 alpha-carbomethoxy-3 alpha-(4-fluorophenyl)tropane
    • Chen N., Sun L. Reith M. E. (2002) Cationic interactions at the human dopamine transporter reveal binding conformations for dopamine distinguishable from those for the cocaine analog 2 alpha-carbomethoxy-3 alpha-(4-fluorophenyl) tropane. J. Neurochem. 81, 1383 1393.
    • (2002) J. Neurochem. , vol.81 , pp. 1383-1393
    • Chen, N.1    Sun, L.2    Reith, M.E.3
  • 17
    • 1242317021 scopus 로고    scopus 로고
    • Aspartate 345 of the Dopamine Transporter Is Critical for Conformational Changes in Substrate Translocation and Cocaine Binding
    • DOI 10.1074/jbc.M306294200
    • Chen N., Rickey J., Berfield J. L. Reith M. E. (2004a) Aspartate 345 of the dopamine transporter is critical for conformational changes in substrate translocation and cocaine binding. J. Biol. Chem. 279, 5508 5519. (Pubitemid 38220576)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.7 , pp. 5508-5519
    • Chen, N.1    Rickey, J.2    Berfield, J.L.3    Reith, M.E.A.4
  • 18
    • 2542420799 scopus 로고    scopus 로고
    • Mutation of Trp84 and Asp313 of the dopamine transporter reveals similar mode of binding interaction for GBR12909 and benztropine as opposed to cocaine
    • DOI 10.1111/j.1471-4159.2004.02386.x
    • Chen N., Zhen J. Reith M. E. (2004b) Mutation of Trp84 and Asp313 of the dopamine transporter reveals similar mode of binding interaction for GBR12909 and benztropine as opposed to cocaine. J. Neurochem. 89, 853 864. (Pubitemid 38684733)
    • (2004) Journal of Neurochemistry , vol.89 , Issue.4 , pp. 853-864
    • Chen, N.1    Zhen, J.2    Reith, M.E.A.3
  • 19
    • 0020585964 scopus 로고
    • Catecholamine secretion from digitonin-treated adrenal medullary chromaffin cells
    • Dunn L. A. Holz R. W. (1983) Catecholamine secretion from digitonin-treated adrenal medullary chromaffin cells. J. Biol. Chem. 258, 4989 4993.
    • (1983) J. Biol. Chem. , vol.258 , pp. 4989-4993
    • Dunn, L.A.1    Holz, R.W.2
  • 20
    • 0035964795 scopus 로고    scopus 로고
    • Dendrodendritic inhibition through reversal of dopamine transport
    • DOI 10.1126/science.1060645
    • Falkenburger B. H., Barstow K. L. Mintz I. M. (2001) Dendrodendritic inhibition through reversal of dopamine transport. Science 293, 2465 2470. (Pubitemid 32917330)
    • (2001) Science , vol.293 , Issue.5539 , pp. 2465-2470
    • Falkenburger, B.H.1    Barstow, K.L.2    Mintz, I.M.3
  • 22
    • 0021921188 scopus 로고
    • Arachidonic acid release and catecholamine secretion from digitonin-treated chromaffin cells: Effects of micromolar calcium, phorbol ester, and protein alkylating agents
    • DOI 10.1111/j.1471-4159.1985.tb07140.x
    • Frye R. A. Holz R. W. (1985) Arachidonic acid release and catecholamine secretion from digitonin-treated chromaffin cells: effects of micromolar calcium, phorbol ester, and protein alkylating agents. J. Neurochem. 44, 265 273. (Pubitemid 15190151)
    • (1985) Journal of Neurochemistry , vol.44 , Issue.1 , pp. 265-273
    • Frye, R.A.1    Holz, R.W.2
  • 24
    • 0030071106 scopus 로고    scopus 로고
    • Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter
    • DOI 10.1038/379606a0
    • Giros B., Jaber M., Jones S. R., Wightman R. M. Caron M. G. (1996) Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter. Nature 379, 606 612. (Pubitemid 26052818)
    • (1996) Nature , vol.379 , Issue.6566 , pp. 606-612
    • Giros, B.1    Jaber, M.2    Jones, S.R.3    Wightman, R.M.4    Caron, M.G.5
  • 25
    • 0033871557 scopus 로고    scopus 로고
    • The use of permeabilized cells to assay protien phosphorylation and catecholamine release
    • DOI 10.1023/A:1007533927813
    • Goncalves C. A., Gottfried C. Dunkley P. R. (2000) The use of permeabilized cells to assay protein phosphorylation and catecholamine release. Neurochem. Res. 25, 885 894. (Pubitemid 30625521)
    • (2000) Neurochemical Research , vol.25 , Issue.6 , pp. 885-894
    • Goncalves, C.A.1    Gottfried, C.2    Dunkley, P.R.3
  • 26
    • 0028979335 scopus 로고
    • [3H]WIN 35,428 ([3H]CFT) binds to multiple charge-states of the solubilized dopamine transporter in primate striatum
    • Gracz L. M. Madras B. K. (1995) [3H]WIN 35,428 ([3H]CFT) binds to multiple charge-states of the solubilized dopamine transporter in primate striatum. J. Pharmacol. Exp. Ther. 273, 1224 1234.
    • (1995) J. Pharmacol. Exp. Ther. , vol.273 , pp. 1224-1234
    • Gracz, L.M.1    Madras, B.K.2
  • 27
    • 0036736366 scopus 로고    scopus 로고
    • Hypoxia and persistent sodium current
    • Hammarstrom A. K. Gage P. W. (2002) Hypoxia and persistent sodium current. Eur. Biophys. J. 31, 323 330.
    • (2002) Eur. Biophys. J. , vol.31 , pp. 323-330
    • Hammarstrom, A.K.1    Gage, P.W.2
  • 28
    • 0032521354 scopus 로고    scopus 로고
    • Mechanisms of amphetamine action revealed in mice lacking the dopamine transporter
    • Jones S. R., Gainetdinov R. R., Wightman R. M. Caron M. G. (1998) Mechanisms of amphetamine action revealed in mice lacking the dopamine transporter. J. Neurosci. 18, 1979 1986. (Pubitemid 28141404)
    • (1998) Journal of Neuroscience , vol.18 , Issue.6 , pp. 1979-1986
    • Jones, S.R.1    Gainetdinov, R.R.2    Mark Wightman, R.3    Caron, M.G.4
  • 29
    • 19344363221 scopus 로고    scopus 로고
    • N-terminal phosphorylation of the dopamine transporter is required for amphetamine-induced efflux
    • DOI 10.1371/journal.pbio.0020078
    • Khoshbouei H., Sen N., Guptaroy B., Johnson L., Lund D., Gnegy M. E., Galli A. Javitch J. A. (2004) N-terminal phosphorylation of the dopamine transporter is required for amphetamine-induced efflux. PLoS Biol. 2, E78. (Pubitemid 39234535)
    • (2004) PLoS Biology , vol.2 , Issue.3
    • Khoshbouei, H.1    Sen, N.2    Guptaroy, B.3    Johnson, L.4    Lund, D.5    Gnegy, M.E.6    Galli, A.7    Javitch, J.A.8
  • 30
    • 0026722234 scopus 로고
    • Dopamine transporter site-directed mutations differentially alter substrate transport and cocaine binding
    • Kitayama S., Shimada S., Xu H., Markham L., Donovan D. M. Uhl G. R. (1992) Dopamine transporter site-directed mutations differentially alter substrate transport and cocaine binding. Proc. Natl Acad. Sci. USA 89, 7782 7785.
    • (1992) Proc. Natl Acad. Sci. USA , vol.89 , pp. 7782-7785
    • Kitayama, S.1    Shimada, S.2    Xu, H.3    Markham, L.4    Donovan, D.M.5    Uhl, G.R.6
  • 31
    • 47749083479 scopus 로고    scopus 로고
    • An intracellular interaction network regulates conformational transitions in the dopamine transporter
    • Kniazeff J., Shi L., Loland C. J., Javitch J. A., Weinstein H. Gether U. (2008) An intracellular interaction network regulates conformational transitions in the dopamine transporter. J. Biol. Chem. 283, 17691 17701.
    • (2008) J. Biol. Chem. , vol.283 , pp. 17691-17701
    • Kniazeff, J.1    Shi, L.2    Loland, C.J.3    Javitch, J.A.4    Weinstein, H.5    Gether, U.6
  • 32
    • 0027428320 scopus 로고
    • Carrier-mediated release of neurotransmitters
    • DOI 10.1016/0166-2236(93)90010-J
    • Levi G. Raiteri M. (1993) Carrier-mediated release of neurotransmitters. Trends Neurosci. 16, 415 419. (Pubitemid 23283403)
    • (1993) Trends in Neurosciences , vol.16 , Issue.10 , pp. 415-419
    • Levi, G.1    Raiteri, M.2
  • 33
    • 0032974887 scopus 로고    scopus 로고
    • Modeling of the interaction of Na+ and K+ with the binding of dopamine and [3H]WIN 35,428 to the human dopamine transporter
    • Li L. B. Reith M. E. (1999) Modeling of the interaction of Na+ and K+ with the binding of dopamine and [3H]WIN 35,428 to the human dopamine transporter. J. Neurochem. 72, 1095 1109.
    • (1999) J. Neurochem. , vol.72 , pp. 1095-1109
    • Li, L.B.1    Reith, M.E.2
  • 35
    • 0028089211 scopus 로고
    • Striatal transporter for dopamine: Catechol structure-activity studies and susceptibility to chemical modification
    • Meiergerd S. M. Schenk J. O. (1994) Striatal transporter for dopamine: catechol structure-activity studies and susceptibility to chemical modification. J. Neurochem. 62, 998 1008. (Pubitemid 24064511)
    • (1994) Journal of Neurochemistry , vol.62 , Issue.3 , pp. 998-1008
    • Meiergerd, S.M.1    Schenk, J.O.2
  • 36
    • 0033568870 scopus 로고    scopus 로고
    • Membrane trafficking regulates the activity of the human dopamine transporter
    • Melikian H. E. Buckley K. M. (1999) Membrane trafficking regulates the activity of the human dopamine transporter. J. Neurosci. 19, 7699 7710. (Pubitemid 30225770)
    • (1999) Journal of Neuroscience , vol.19 , Issue.18 , pp. 7699-7710
    • Melikian, H.E.1    Buckley, K.M.2
  • 37
    • 51349157554 scopus 로고    scopus 로고
    • Genetic complementation screen identifies a mitogen-activated protein kinase phosphatase, MKP3, as a regulator of dopamine transporter trafficking
    • Mortensen O. V., Larsen M. B., Prasad B. M. Amara S. G. (2008) Genetic complementation screen identifies a mitogen-activated protein kinase phosphatase, MKP3, as a regulator of dopamine transporter trafficking. Mol. Biol. Cell 19, 2818 2829.
    • (2008) Mol. Biol. Cell , vol.19 , pp. 2818-2829
    • Mortensen, O.V.1    Larsen, M.B.2    Prasad, B.M.3    Amara, S.G.4
  • 38
    • 0032480011 scopus 로고    scopus 로고
    • Delineation of an endogenous zinc-binding site in the human dopamine transporter
    • DOI 10.1093/emboj/17.15.4266
    • Norregaard L., Frederiksen D., Nielsen E. O. Gether U. (1998) Delineation of an endogenous zinc-binding site in the human dopamine transporter. EMBO J. 17, 4266 4273. (Pubitemid 28362617)
    • (1998) EMBO Journal , vol.17 , Issue.15 , pp. 4266-4273
    • Norregaard, L.1    Frederiksen, D.2    Nielsen, E.O.3    Gether, U.4
  • 39
    • 41149130280 scopus 로고    scopus 로고
    • Labeling of dopamine transporter transmembrane domain 1 with the tropane ligand N-[4-(4-azido-3-[125I]iodophenyl)butyl]-2beta-carbomethoxy-3beta-(4- chlorophenyl) tropane implicates proximity of cocaine and substrate active sites
    • Parnas M. L., Gaffaney J. D., Zou M. F., Lever J. R., Newman A. H. Vaughan R. A. (2008) Labeling of dopamine transporter transmembrane domain 1 with the tropane ligand N-[4-(4-azido-3-[125I]iodophenyl)butyl]-2beta- carbomethoxy-3beta-(4-chlorophenyl) tropane implicates proximity of cocaine and substrate active sites. Mol. Pharmacol. 73, 1141 1150.
    • (2008) Mol. Pharmacol. , vol.73 , pp. 1141-1150
    • Parnas, M.L.1    Gaffaney, J.D.2    Zou, M.F.3    Lever, J.R.4    Newman, A.H.5    Vaughan, R.A.6
  • 40
    • 58549112947 scopus 로고    scopus 로고
    • Zinc regulates the dopamine transporter in a membrane potential and chloride dependent manner
    • 540.
    • Pifl C., Wolf A., Rebernik P., Reither H. Berger M. L. (2008) Zinc regulates the dopamine transporter in a membrane potential and chloride dependent manner. Neuropharmacology 56, 531 540.
    • (2008) Neuropharmacology , vol.56 , pp. 531
    • Pifl, C.1    Wolf, A.2    Rebernik, P.3    Reither, H.4    Berger, M.L.5
  • 41
    • 33748748222 scopus 로고    scopus 로고
    • State-dependent conformations of the translocation pathway in the tyrosine transporter Tyt1, a novel neurotransmitter:sodium symporter from Fusobacterium nucleatum
    • DOI 10.1074/jbc.M602438200
    • Quick M., Yano H., Goldberg N. R., Duan L., Beuming T., Shi L., Weinstein H. Javitch J. A. (2006) State-dependent conformations of the translocation pathway in the tyrosine transporter Tyt1, a novel neurotransmitter:sodium symporter from Fusobacterium nucleatum. J. Biol. Chem. 281, 26444 26454. (Pubitemid 44401853)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.36 , pp. 26444-26454
    • Quick, M.1    Yano, H.2    Goldberg, N.R.3    Duan, L.4    Beuming, T.5    Shi, L.6    Weinstein, H.7    Javitch, J.A.8
  • 42
    • 0026611161 scopus 로고
    • Cocaine binding sites in mouse striatum, dopamine autoreceptors, and cocaine-induced locomotion
    • Reith M. E. Selmeci G. (1992) Cocaine binding sites in mouse striatum, dopamine autoreceptors, and cocaine-induced locomotion. Pharmacol. Biochem. Behav. 41, 227 230.
    • (1992) Pharmacol. Biochem. Behav. , vol.41 , pp. 227-230
    • Reith, M.E.1    Selmeci, G.2
  • 43
    • 0026469609 scopus 로고
    • Evidence for mutually exclusive binding of cocaine, BTCP, GBR
    • 12935, and dopamine to the dopamine transporter.
    • Reith M. E., de C. B., Rice K. C. Jacobson A. E. (1992) Evidence for mutually exclusive binding of cocaine, BTCP, GBR 12935, and dopamine to the dopamine transporter. Eur. J. Pharmacol. 227, 417 425.
    • (1992) Eur. J. Pharmacol. , vol.227 , pp. 417-425
    • Reith, M.E.1    De, C.B.2    Rice, K.C.3    Jacobson, A.E.4
  • 44
    • 49449118198 scopus 로고    scopus 로고
    • Dopamine spillover after quantal release: Rethinking dopamine transmission in the nigrostriatal pathway
    • Rice M. E. Cragg S. J. (2008) Dopamine spillover after quantal release: rethinking dopamine transmission in the nigrostriatal pathway. Brain Res. Rev. 58, 303 313.
    • (2008) Brain Res. Rev. , vol.58 , pp. 303-313
    • Rice, M.E.1    Cragg, S.J.2
  • 45
    • 0035218082 scopus 로고    scopus 로고
    • Amphetamine-type central nervous system stimulants release norepinephrine more potently than they release dopamine and serotonin
    • Rothman R. B., Baumann M. H., Dersch C. M., Romero D. V., Rice K. C., Carroll F. I. Partilla J. S. (2001) Amphetamine-type central nervous system stimulants release norepinephrine more potently than they release dopamine and serotonin. Synapse 39, 32 41.
    • (2001) Synapse , vol.39 , pp. 32-41
    • Rothman, R.B.1    Baumann, M.H.2    Dersch, C.M.3    Romero, D.V.4    Rice, K.C.5    Carroll, F.I.6    Partilla, J.S.7
  • 46
    • 44949086583 scopus 로고    scopus 로고
    • The mechanism of a neurotransmitter:sodium symporter - Inward release of Na+ and substrate is triggered by substrate in a second binding site
    • Shi L., Quick M., Zhao Y., Weinstein H. Javitch J. A. (2008) The mechanism of a neurotransmitter:sodium symporter - inward release of Na+ and substrate is triggered by substrate in a second binding site. Mol. Cell 30, 667 677.
    • (2008) Mol. Cell , vol.30 , pp. 667-677
    • Shi, L.1    Quick, M.2    Zhao, Y.3    Weinstein, H.4    Javitch, J.A.5
  • 47
    • 34548178234 scopus 로고    scopus 로고
    • Antidepressant binding site in a bacterial homologue of neurotransmitter transporters
    • DOI 10.1038/nature06038, PII NATURE06038
    • Singh S. K., Yamashita A. Gouaux E. (2007) Antidepressant binding site in a bacterial homologue of neurotransmitter transporters. Nature 448, 952 956. (Pubitemid 47312772)
    • (2007) Nature , vol.448 , Issue.7156 , pp. 952-956
    • Singh, S.K.1    Yamashita, A.2    Gouaux, E.3
  • 48
    • 33748146552 scopus 로고    scopus 로고
    • RNA interference screen reveals an essential role of Nedd4-2 in dopamine transporter ubiquitination and endocytosis
    • DOI 10.1523/JNEUROSCI.1301-06.2006
    • Sorkina T., Miranda M., Dionne K. R., Hoover B. R., Zahniser N. R. Sorkin A. (2006) RNA interference screen reveals an essential role of Nedd4-2 in dopamine transporter ubiquitination and endocytosis. J. Neurosci. 26, 8195 8205. (Pubitemid 44315144)
    • (2006) Journal of Neuroscience , vol.26 , Issue.31 , pp. 8195-8205
    • Sorkina, T.1    Miranda, M.2    Dionne, K.R.3    Hoover, B.R.4    Zahniser, N.R.5    Sorkin, A.6
  • 50
    • 20444499405 scopus 로고    scopus 로고
    • 2 adrenoceptor binding site with catechol reveals differences in binding and activation by agonists and partial agonists
    • DOI 10.1074/jbc.M502352200
    • Swaminath G., Deupi X., Lee T. W., Zhu W., Thian F. S., Kobilka T. S. Kobilka B. (2005) Probing the beta2 adrenoceptor binding site with catechol reveals differences in binding and activation by agonists and partial agonists. J. Biol. Chem. 280, 22165 22171. (Pubitemid 40827872)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.23 , pp. 22165-22171
    • Swaminath, G.1    Deupi, X.2    Lee, T.W.3    Zhu, W.4    Thian, F.S.5    Kobilka, T.S.6    Kobilka, B.7
  • 51
    • 0035117112 scopus 로고    scopus 로고
    • Differential sensitivity to NaCl for inhibitors and substrates that recognize mutually exclusive binding sites on the neuronal transporter of dopamine in rat striatal membranes
    • DOI 10.1016/S0168-0102(00)00230-3, PII S0168010200002303
    • Tidjane C. A., Do-Rego J. C., Costentin J. Bonnet J. J. (2001) Differential sensitivity to NaCl for inhibitors and substrates that recognize mutually exclusive binding sites on the neuronal transporter of dopamine in rat striatal membranes. Neurosci. Res. 39, 319 325. (Pubitemid 32186384)
    • (2001) Neuroscience Research , vol.39 , Issue.3 , pp. 319-325
    • Tidjane Corera, A.1    Do-Rego, J.-C.2    Costentin, J.3    Bonnet, J.-J.4
  • 52
    • 0042844641 scopus 로고    scopus 로고
    • Dissociation of high-affinity cocaine analog binding and dopamine uptake inhibition at the dopamine transporter
    • DOI 10.1124/mol.64.2.430
    • Wang W., Sonders M. S., Ukairo O. T., Scott H., Kloetzel M. K. Surratt C. K. (2003) Dissociation of high-affinity cocaine analog binding and dopamine uptake inhibition at the dopamine transporter. Mol. Pharmacol. 64, 430 439. (Pubitemid 36910007)
    • (2003) Molecular Pharmacology , vol.64 , Issue.2 , pp. 430-439
    • Wang, W.1    Sonders, M.S.2    Ukairo, O.T.3    Scott, H.4    Kloetzel, M.K.5    Surratt, C.K.6
  • 53
    • 0020586584 scopus 로고
    • Calcium-evoked secretion from digitonin-permeabilized adrenal medullary chromaffin cells
    • Wilson S. P. Kirshner N. (1983) Calcium-evoked secretion from digitonin-permeabilized adrenal medullary chromaffin cells. J. Biol. Chem. 258, 4994 5000.
    • (1983) J. Biol. Chem. , vol.258 , pp. 4994-5000
    • Wilson, S.P.1    Kirshner, N.2
  • 54
    • 0030611085 scopus 로고    scopus 로고
    • 3H] WIN 35,428 binding to the human dopamine transporter in a similar fashion
    • Wu Q., Coffey L. L. Reith M. E. (1997) Cations affect [3H]mazindol and [3H]WIN 35,428 binding to the human dopamine transporter in a similar fashion. J. Neurochem. 69, 1106 1118. (Pubitemid 27364831)
    • (1997) Journal of Neurochemistry , vol.69 , Issue.3 , pp. 1106-1118
    • Wu, Q.1    Coffey, L.L.2    Reith, M.E.A.3
  • 55
    • 49449102752 scopus 로고    scopus 로고
    • Coordination of Na(+) by monoamine ligands in dopamine, norepinephrine, and serotonin transporters
    • Xhaard H., Backstrom V., Denessiouk K. Johnson M. S. (2008) Coordination of Na(+) by monoamine ligands in dopamine, norepinephrine, and serotonin transporters. J. Chem. Inf. Model 48, 1423 1437.
    • (2008) J. Chem. Inf. Model , vol.48 , pp. 1423-1437
    • Xhaard, H.1    Backstrom, V.2    Denessiouk, K.3    Johnson, M.S.4
  • 58
    • 26944446958 scopus 로고    scopus 로고
    • + gradient and membrane potential: Dopamine versus other substrates
    • DOI 10.1016/j.neuropharm.2005.07.002, PII S0028390805002467, New Perspectives in Neurotransmitter Transporter Biology
    • Zhen J., Chen N. Reith M. E. (2005) Differences in interactions with the dopamine transporter as revealed by diminishment of Na(+) gradient and membrane potential: dopamine versus other substrates. Neuropharmacology 49, 769 779. (Pubitemid 41483883)
    • (2005) Neuropharmacology , vol.49 , Issue.6 , pp. 769-779
    • Zhen, J.1    Chen, N.2    Reith, M.E.A.3
  • 59
    • 34548684744 scopus 로고    scopus 로고
    • LeuT-desipramine structure reveals how antidepressants block neurotransmitter reuptake
    • DOI 10.1126/science.1147614
    • Zhou Z., Zhen J., Karpowich N. K., Goetz R. M., Law C. J., Reith M. E. Wang D. N. (2007) LeuT-desipramine structure reveals how antidepressants block neurotransmitter reuptake. Science 317, 1390 1393. (Pubitemid 47417479)
    • (2007) Science , vol.317 , Issue.5843 , pp. 1390-1393
    • Zhou, Z.1    Zhen, J.2    Karpowich, N.K.3    Goetz, R.M.4    Law, C.J.5    Reith, M.E.A.6    Wang, D.-N.7
  • 60
    • 0024791996 scopus 로고
    • Comparison of characteristics of dopamine uptake and mazindol binding in mouse striatum
    • DOI 10.1007/BF00717737
    • Zimanyi I., Lajtha A. Reith M. E. (1989) Comparison of characteristics of dopamine uptake and mazindol binding in mouse striatum. Naunyn Schmiedebergs Arch. Pharmacol. 340, 626 632. (Pubitemid 20023149)
    • (1989) Naunyn-Schmiedeberg's Archives of Pharmacology , vol.340 , pp. 626-632
    • Zimanyi, I.1    Lajtha, A.2    Reith, M.E.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.