A synthetic NCAM-derived mimetic peptide, FGL, exerts anti-inflammatory properties via IGF-1 and interferon-γ modulation

Journal of Neurochemistry

Volumn 109, Issue 5, 2009, Pages 1516-1525

  Downer, Eric J ^a   Cowley, Thelma R ^a   Cox, Fionnuala ^a   Maher, Francis O ^a   Berezin, Vladimir ^b   Bock, Elisabeth ^b   Lynch, Marina A ^a  

^a TRINITY COLLEGE DUBLIN   (Ireland)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Age; CD200; Insulin like growth factor 1; Interferon ; Microglia; Neural cell adhesion molecule

Indexed keywords

ANTIINFLAMMATORY AGENT; CD200 LIGAND; CD40 ANTIGEN; FG LOOP PEPTIDE; GAMMA INTERFERON; LIGAND; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; PROTEIN KINASE B; SOMATOMEDIN C; SYNTHETIC PEPTIDE; UNCLASSIFIED DRUG;

AGED; AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BRAIN NERVE CELL; CELL ACTIVATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG MECHANISM; ENZYME PHOSPHORYLATION; GLIA CELL; HIPPOCAMPUS; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN SECRETION; RAT;

AGE FACTORS; ANIMALS; ANIMALS, NEWBORN; ANTI-INFLAMMATORY AGENTS; ANTIGENS, CD; ANTIGENS, CD40; CELLS, CULTURED; CEREBRAL CORTEX; GENE EXPRESSION REGULATION; HIPPOCAMPUS; INSULIN-LIKE GROWTH FACTOR I; INTERFERON-GAMMA; MALE; NEURAL CELL ADHESION MOLECULES; NEUROGLIA; NEURONS; ONCOGENE PROTEIN V-AKT; RATS; RATS, WISTAR;

RATTUS;

EID: 65549163176     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2009.06076.x     Document Type: Article

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