메뉴 건너뛰기




Volumn 84, Issue 3, 2003, Pages 546-556

The role of phosphatidylinositol 3-kinase in neural cell adhesion molecule-mediated neuronal differentiation and survival

Author keywords

Akt; Apoptosis; C3; Cell adhesion; Neurones

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; C3 PROTEIN; CYCLIC AMP DEPENDENT PROTEIN KINASE; DNA FRAGMENT; FIBROBLAST GROWTH FACTOR RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; NERVE CELL ADHESION MOLECULE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN KINASE C; PROTEIN SERINE THREONINE KINASE; RAS PROTEIN; UNCLASSIFIED DRUG; WORTMANNIN;

EID: 0037312111     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2003.01538.x     Document Type: Article
Times cited : (103)

References (35)
  • 1
    • 0030887348 scopus 로고    scopus 로고
    • NCAM140 interacts with the focal adhesion kinase p125 (fak) and the SRC-related tyrosine kinase p59 (fyn)
    • Beggs H. E., Baragona S. C., Hemperly J. J. and Maness P. F. (1997) NCAM140 interacts with the focal adhesion kinase p125 (fak) and the SRC-related tyrosine kinase p59 (fyn). J. Biol. Chem. 272, 8310-8319.
    • (1997) J. Biol. Chem. , vol.272 , pp. 8310-8319
    • Beggs, H.E.1    Baragona, S.C.2    Hemperly, J.J.3    Maness, P.F.4
  • 3
    • 0035369623 scopus 로고    scopus 로고
    • Transcription-dependent and -independent control of neuronal survival by the PI3K-Akt signaling pathway
    • Brunet A., Datta S. R. and Greenberg M. E. (2001) Transcription- dependent and -independent control of neuronal survival by the PI3K-Akt signaling pathway. Curr. Opin. Neurobiol. 11, 297-305.
    • (2001) Curr. Opin. Neurobiol. , vol.11 , pp. 297-305
    • Brunet, A.1    Datta, S.R.2    Greenberg, M.E.3
  • 4
    • 0029979722 scopus 로고    scopus 로고
    • Phosphorylation of tyrosine 397 in focal adhesion kinase is required for binding phosphatidylinositol 3-kinase
    • Chen H. C., Appeddu P. A., Isoda H. and Guan J. L. (1996) Phosphorylation of tyrosine 397 in focal adhesion kinase is required for binding phosphatidylinositol 3-kinase. J. Biol. Chem. 271, 26329-26334.
    • (1996) J. Biol. Chem. , vol.271 , pp. 26329-26334
    • Chen, H.C.1    Appeddu, P.A.2    Isoda, H.3    Guan, J.L.4
  • 5
    • 0032919002 scopus 로고    scopus 로고
    • Prevention of neuronal cell death by neural adhesion molecules L1 and CHL1
    • Chen S., Mantei N., Dong L. and Schachner M. (1999) Prevention of neuronal cell death by neural adhesion molecules L1 and CHL1. J. Neurobiol. 38, 428-439.
    • (1999) J. Neurobiol. , vol.38 , pp. 428-439
    • Chen, S.1    Mantei, N.2    Dong, L.3    Schachner, M.4
  • 6
    • 0032189381 scopus 로고    scopus 로고
    • Protein kinase B (c-Akt): A multifunctional mediator of phosphatidylinositol 3-kinase activation
    • Coffer P. J., Jin J. and Woodgett J. R. (1998) Protein kinase B (c-Akt): a multifunctional mediator of phosphatidylinositol 3-kinase activation. Biochem. J. 335, 1-13.
    • (1998) Biochem. J. , vol.335 , pp. 1-13
    • Coffer, P.J.1    Jin, J.2    Woodgett, J.R.3
  • 7
    • 0027955570 scopus 로고
    • And inactivation of the N-CAM gene in mice results in size reduction of the olfactory bulb and deficits in spatial learning
    • Cremer H., Lange R., Christoph A., Plomann M., Vopper G., Roes J., Brown R., Baldwin S., Kraemer P. and Scheff S. (1994) and inactivation of the N-CAM gene in mice results in size reduction of the olfactory bulb and deficits in spatial learning. Nature 367, 455-459.
    • (1994) Nature , vol.367 , pp. 455-459
    • Cremer, H.1    Lange, R.2    Christoph, A.3    Plomann, M.4    Vopper, G.5    Roes, J.6    Brown, R.7    Baldwin, S.8    Kraemer, P.9    Scheff, S.10
  • 8
    • 0034088446 scopus 로고    scopus 로고
    • Cellular signaling by neural cell adhesion molecules of the immunoglobulin superfamily
    • Crossin K. L. and Krushel L. A. (2000) Cellular signaling by neural cell adhesion molecules of the immunoglobulin superfamily. Dev. Dyn. 218, 260-279.
    • (2000) Dev. Dyn. , vol.218 , pp. 260-279
    • Crossin, K.L.1    Krushel, L.A.2
  • 9
    • 0032752063 scopus 로고    scopus 로고
    • Cellular survival: A play in three Akts
    • Datta S. R., Brunet A. and Greenberg M. E. (1999) Cellular survival: a play in three Akts. Genes Dev 13, 2905-2927.
    • (1999) Genes Dev. , vol.13 , pp. 2905-2927
    • Datta, S.R.1    Brunet, A.2    Greenberg, M.E.3
  • 11
    • 0026776017 scopus 로고
    • Intraventricular infusions of anti-neural cell adhesion molecules in a discrete posttraining period impair consolidation of a passive avoidance response in the rat
    • Doyle E., Nolan P. M., Bell R. and Regan C. M. (1992) Intraventricular infusions of anti-neural cell adhesion molecules in a discrete posttraining period impair consolidation of a passive avoidance response in the rat. J. Neurochem. 59, 1570-1573.
    • (1992) J. Neurochem. , vol.59 , pp. 1570-1573
    • Doyle, E.1    Nolan, P.M.2    Bell, R.3    Regan, C.M.4
  • 12
    • 0035094532 scopus 로고    scopus 로고
    • Integrin signaling via the PI3-kinase-Akt pathway increases neuronal resistance to glutamate-induced apoptosis
    • Gary D. S. and Mattson M. P. (2001) Integrin signaling via the PI3-kinase-Akt pathway increases neuronal resistance to glutamate-induced apoptosis. J. Neurochem. 76, 1485-1496.
    • (2001) J. Neurochem. , vol.76 , pp. 1485-1496
    • Gary, D.S.1    Mattson, M.P.2
  • 13
    • 0035003589 scopus 로고    scopus 로고
    • Cascade of caspase activation in potassium-deprived cerebellar granule neurons: Targets for treatment with peptide and protein inhibitors of apoptosis
    • Gerhardt E., Kugler S., Leist M., Beier C., Berliocchi L., Volbracht C., Weller M., Bahr M., Nicotera P. and Schulz J. B. (2001) Cascade of caspase activation in potassium-deprived cerebellar granule neurons: targets for treatment with peptide and protein inhibitors of apoptosis. Mol. Cell Neurosci. 17, 717-731.
    • (2001) Mol. Cell Neurosci. , vol.17 , pp. 717-731
    • Gerhardt, E.1    Kugler, S.2    Leist, M.3    Beier, C.4    Berliocchi, L.5    Volbracht, C.6    Weller, M.7    Bahr, M.8    Nicotera, P.9    Schulz, J.B.10
  • 14
    • 0000046089 scopus 로고
    • A human beta-actin expression vector system directs high-level accumulation of antisense transcripts
    • Gunning P., Leavitt J., Muscat G., Ng S. Y. and Kedes L. (1987) A human beta-actin expression vector system directs high-level accumulation of antisense transcripts. Proc. Natl Acad. Sci. USA 84, 4831-4835.
    • (1987) Proc. Natl Acad. Sci. USA , vol.84 , pp. 4831-4835
    • Gunning, P.1    Leavitt, J.2    Muscat, G.3    Ng, S.Y.4    Kedes, L.5
  • 15
    • 0032527596 scopus 로고    scopus 로고
    • L1 neural cell adhesion molecule is a survival factor for fetal dopaminergic neurons
    • Hulley P., Schachner M. and Lubbert H. (1998) L1 neural cell adhesion molecule is a survival factor for fetal dopaminergic neurons. J. Neurosci. Res. 53, 129-134.
    • (1998) J. Neurosci. Res. , vol.53 , pp. 129-134
    • Hulley, P.1    Schachner, M.2    Lubbert, H.3
  • 17
    • 0029911373 scopus 로고    scopus 로고
    • Functional characterization of NCAM fibronectin type III domains: Demonstration of modulatory effects of the proline-rich sequence encoded by alternatively spliced exons a and AAG
    • Kasper C., Stahlhut M., Berezin V., Maar T. E., Edvardsen K., Kiselyov V. V., Soroka V. and Bock E. (1996) Functional characterization of NCAM fibronectin type III domains: demonstration of modulatory effects of the proline-rich sequence encoded by alternatively spliced exons a and AAG. J. Neurosci. Res. 46, 173-186.
    • (1996) J. Neurosci. Res. , vol.46 , pp. 173-186
    • Kasper, C.1    Stahlhut, M.2    Berezin, V.3    Maar, T.E.4    Edvardsen, K.5    Kiselyov, V.V.6    Soroka, V.7    Bock, E.8
  • 20
    • 0029831486 scopus 로고    scopus 로고
    • Platelet-derived growth factor-dependent activation of phosphatidylinositol 3-kinase is regulated by receptor binding of SH2-domain-containing proteins which influence Ras activity
    • Klinghoffer R. A., Duckworth B., Valius M., Cantley L. and Kazlauskas A. (1996) Platelet-derived growth factor-dependent activation of phosphatidylinositol 3-kinase is regulated by receptor binding of SH2-domain-containing proteins which influence Ras activity. Mol. Cell Biol. 16, 5905-5914.
    • (1996) Mol. Cell Biol. , vol.16 , pp. 5905-5914
    • Klinghoffer, R.A.1    Duckworth, B.2    Valius, M.3    Cantley, L.4    Kazlauskas, A.5
  • 22
    • 0035448912 scopus 로고    scopus 로고
    • Myocyte enhancer factor 2A and 2D undergo phosphorylation and caspase-mediated degradation during apoptosis of rat cerebellar granule neurons
    • Li M., Linseman D. A., Allen M. P., Meintzer M. K., Wang X., Laessig T., Wierman M. E. and Heidenreich K. A. (2001) Myocyte enhancer factor 2A and 2D undergo phosphorylation and caspase- mediated degradation during apoptosis of rat cerebellar granule neurons. J. Neurosci. 21, 6544-6552.
    • (2001) J. Neurosci. , vol.21 , pp. 6544-6552
    • Li, M.1    Linseman, D.A.2    Allen, M.P.3    Meintzer, M.K.4    Wang, X.5    Laessig, T.6    Wierman, M.E.7    Heidenreich, K.A.8
  • 23
    • 0033557640 scopus 로고    scopus 로고
    • Distinct mechanisms underlie neurotoxin -mediated cell death in cultured dopaminergic neurons
    • Lotharius J., Dugan L. L. and O'Malley K. L. (1999) Distinct mechanisms underlie neurotoxin -mediated cell death in cultured dopaminergic neurons. J. Neurosci. 19, 1284-1293.
    • (1999) J. Neurosci. , vol.19 , pp. 1284-1293
    • Lotharius, J.1    Dugan, L.L.2    O'Malley, K.L.3
  • 24
    • 0035933094 scopus 로고    scopus 로고
    • Stimulation of phosphatidylinositol 3-kinase by fibroblast growth factor receptors is mediated by coordinated recruitment of multiple docking proteins
    • Ong S. H., Hadari Y. R., Gotoh N., Guy G. R., Schlessinger J. and Lax I. (2001) Stimulation of phosphatidylinositol 3-kinase by fibroblast growth factor receptors is mediated by coordinated recruitment of multiple docking proteins. Proc. Natl Acad. Sci. USA 98, 6074-6079.
    • (2001) Proc. Natl Acad. Sci. USA , vol.98 , pp. 6074-6079
    • Ong, S.H.1    Hadari, Y.R.2    Gotoh, N.3    Guy, G.R.4    Schlessinger, J.5    Lax, I.6
  • 25
    • 0031752434 scopus 로고    scopus 로고
    • Inhibition of phosphatidylinositol 3-kinase activity blocks cellular differentiation mediated by glial cell line-derived neurotrophic factor in dopaminergic neurons
    • Pong K., Xu R. Y., Baron W. F., Louis J. C. and Beck K. D. (1998) Inhibition of phosphatidylinositol 3-kinase activity blocks cellular differentiation mediated by glial cell line-derived neurotrophic factor in dopaminergic neurons. J. Neurochem. 71, 1912-1919.
    • (1998) J. Neurochem. , vol.71 , pp. 1912-1919
    • Pong, K.1    Xu, R.Y.2    Baron, W.F.3    Louis, J.C.4    Beck, K.D.5
  • 26
    • 0032434753 scopus 로고    scopus 로고
    • The neural cell adhesion molecule (NCAM) in development and plasticity of the nervous system
    • Rønn L. C., Hartz B. P. and Bock E. (1998) The neural cell adhesion molecule (NCAM) in development and plasticity of the nervous system. Exp. Gerontol. 33, 853-864.
    • (1998) Exp. Gerontol. , vol.33 , pp. 853-864
    • Rønn, L.C.1    Hartz, B.P.2    Bock, E.3
  • 28
    • 0034011003 scopus 로고    scopus 로고
    • The neural cell adhesion molecule in synaptic plasticity and ageing
    • Rønn L. C., Berezin V. and Bock E. (2000a) The neural cell adhesion molecule in synaptic plasticity and ageing. Int. J. Dev Neurosci. 18, 193-199.
    • (2000) Int. J. Dev Neurosci. , vol.18 , pp. 193-199
    • Rønn, L.C.1    Berezin, V.2    Bock, E.3
  • 29
    • 0033914334 scopus 로고    scopus 로고
    • Neurite outgrowth induced by a synthetic peptide ligand of neural cell adhesion molecule requires fibroblast growth factor receptor activation
    • Rønn L. C., Doherty P., Holm A., Berezin V. and Bock E. (2000b) Neurite outgrowth induced by a synthetic peptide ligand of neural cell adhesion molecule requires fibroblast growth factor receptor activation. J. Neurochem. 75, 665-671.
    • (2000) J. Neurochem. , vol.75 , pp. 665-671
    • Rønn, L.C.1    Doherty, P.2    Holm, A.3    Berezin, V.4    Bock, E.5
  • 31
    • 0027261388 scopus 로고
    • A role for the neural cell adhesion molecule in a late, consolidating phase of glycoprotein synthesis six hours following passive avoidance training of the young chick
    • Scholey A. B., Rose S. P., Zamani M. R., Bock E. and Schachner M. (1993) A role for the neural cell adhesion molecule in a late, consolidating phase of glycoprotein synthesis six hours following passive avoidance training of the young chick. Neuroscience 55, 499-509.
    • (1993) Neuroscience , vol.55 , pp. 499-509
    • Scholey, A.B.1    Rose, S.P.2    Zamani, M.R.3    Bock, E.4    Schachner, M.5
  • 32
    • 0001607156 scopus 로고
    • Preparation of primary cultures of mouse (rat) cerebellar granule neurons
    • Shahar A. De Vellis J., Vernadakis A. and Haber B., eds. Alan R. Liss, New York
    • Schousboe A., Meier E., Drejer J. and Hertz L. (1989) Preparation of primary cultures of mouse (rat) cerebellar granule neurons, in A Dissection and Tissue Culture Manual of the Nervous System (Shahar A., De Vellis J., Vernadakis A. and Haber B., eds), pp. 203-206. Alan R. Liss, New York.
    • (1989) A Dissection and Tissue Culture Manual of the Nervous System , pp. 203-206
    • Schousboe, A.1    Meier, E.2    Drejer, J.3    Hertz, L.4
  • 33
    • 0034664960 scopus 로고    scopus 로고
    • A new phosphospecific cell-based ELISA for p42/p44 mitogen- activated protein kinase (MAPK), p38 MAPK, protein kinase B and cAMP-response-element-binding protein
    • Versteeg H. H., Nijhuis E., van den Brink G. R., Evertzen M., van Pynaert G. N. D. S., Coffer P. J. and Peppelenbosch M. P. (2000) A new phosphospecific cell-based ELISA for p42/p44 mitogen- activated protein kinase (MAPK), p38 MAPK, protein kinase B and cAMP-response-element-binding protein. Biochem. J. 350, 717-722.
    • (2000) Biochem. J. , vol.350 , pp. 717-722
    • Versteeg, H.H.1    Nijhuis, E.2    Van den Brink, G.R.3    Evertzen, M.4    Van Pynaert, G.N.D.S.5    Coffer, P.J.6    Peppelenbosch, M.P.7
  • 35
    • 0029123586 scopus 로고
    • PC12-E2 cells: A stable variant with altered responses to growth factor stimulation
    • Wu Y. Y. and Bradshaw R. A. (1995) PC12-E2 cells: a stable variant with altered responses to growth factor stimulation. J. Cell Physiol. 164, 522-532.
    • (1995) J. Cell Physiol. , vol.164 , pp. 522-532
    • Wu, Y.Y.1    Bradshaw, R.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.