Bypassing pathogen-induced inflammasome activation for the regulation of interleukin-1β production by the fungal pathogen candida albicans

Journal of Infectious Diseases

Volumn 199, Issue 7, 2009, Pages 1087-1096

  Van De Veerdonk, Frank L ^a,b   Joosten, Leo A B ^a,b   Devesa, Isabel ^a,b   Héctor, M Mora Montes ^c   Kanneganti, Thirumala Devi ^d   Dinarello, Charles A ^e   Van Der Meer, Jos W M ^a,b   Gow, Neil A R ^c   Kullberg, Bart Jan ^a,b   Netea, Mihai G ^a,b  

^a Department of Medicine ^*  (Netherlands)

^b RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^c UNIVERSITY OF ABERDEEN   (United Kingdom)

^d ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^e UNIVERSITY OF COLORADO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; BETA GLUCAN; CHITIN; CRYOPYRIN; DECTIN 1; INFLAMMASOME; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; MANNAN; MANNOSE RECEPTOR; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 9; UNCLASSIFIED DRUG; APOPTOSIS REGULATORY PROTEIN; CALCIUM BINDING PROTEIN; CARRIER PROTEIN; CIAS1 PROTEIN, MOUSE; IPAF PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANDIDA ALBICANS; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME ACTIVATION; FUNGAL STRAIN; FUNGAL VIRULENCE; FUNGUS MUTANT; GENETIC TRANSCRIPTION; HUMAN; MONOCYTE; MOUSE; NONHUMAN; NORMAL HUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN SECRETION; ANIMAL; CELL CULTURE; GENETICS; IMMUNOLOGY; INFLAMMATION; MACROPHAGE; METABOLISM; MICROBIOLOGY; MONONUCLEAR CELL; PHYSIOLOGY;

ANIMALS; APOPTOSIS REGULATORY PROTEINS; CALCIUM-BINDING PROTEINS; CANDIDA ALBICANS; CARRIER PROTEINS; CASPASE 1; CELLS, CULTURED; HUMANS; INFLAMMATION; INTERLEUKIN-1BETA; LEUKOCYTES, MONONUCLEAR; MACROPHAGES; MICE;

EID: 65549149437     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1086/597274     Document Type: Article

References (50)

1. Wisplinghoff H, Bischoff T, Tallent SM, Seifert H, Wenzel RP, Edmond MB. Nosocomial bloodstream infections in US hospitals: analysis of 24,179 cases from a prospective nationwide surveillance study. Clin Infect Dis 2004; 39(3):309-17.
2. Marchetti O, Bille J, Fluckiger U, et al. Epidemiology of candidemia in Swiss tertiary care hospitals: secular trends, 1991-2000. Clin Infect Dis 2004; 38(3):311-20.
3. Gudlaugsson O, Gillespie S, Lee K, et al. Attributable mortality of nosocomial candidemia, revisited. Clin Infect Dis 2003; 37(9):1172-7.
4. Dimopoulos G, Karabinis A, Samonis G, Falagas ME. Candidemia in immunocompromised and immunocompetent critically ill patients: a prospective comparative study. Eur J Clin Microbiol Infect Dis 2007; 26(6):377-84.
5. Maródi L, Korchak HM, Johnston RB Jr. Mechanisms of host defense against Candida species. I. Phagocytosis by monocytes and monocytederived macrophages. J Immunol 1991; 146(8):2783-9.
6. Kullberg BJ, van 't Wout JW, van Furth R. Role of granulocytes in increased host resistance to Candida albicans induced by recombinant interleukin-1. Infect Immun 1990; 58(10):3319-24.
7. Wisplinghoff H, Bischoff T, Tallent SM, Seifert H, Wenzel RP, Edmond MB. Nosocomial bloodstream infections in US hospitals: analysis of 24,179 cases from a prospective nationwide surveillance study. Clin Infect Dis 2004; 39(3):309-17.
8. Kaposzta R, Tree P, Marodi L, Gordon S. Characteristics of invasive candidiasis in gamma interferon-and interleukin-4-deficient mice: role of macrophages in host defense against Candida albicans. Infect Immun 1998; 66(4):1708-17.
9. Vonk AG, Netea MG, van Krieken JH, Iwakura Y, van der Meer JW, Kullberg BJ. Endogenous interleukin (IL)-1- and IL-1- are crucial for host defense against disseminated candidiasis. J Infect Dis 2006; 193(10):1419-26.
10. Dinarello CA. Interleukin-18. Methods 1999; 19(1):121-32.
11. Kahlenberg JM, Dubyak GR. Mechanisms of caspase-1 activation by P2X7 receptor-mediated K- release. Am J Physiol Cell Physiol 2004; 286(5):C1100-8.
12. Martinon F, Burns K, Tschopp J. The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-. Mol Cell 2002; 10(2):417-26.
13. Sutterwala FS, Ogura Y, Szczepanik M, et al. Critical role for NALP3/ CIAS1/Cryopyrin in innate and adaptive immunity through its regulation of caspase-1. Immunity 2006; 24(3):317-27.
14. Becker CE, O'Neill LA. Inflammasomes in inflammatory disorders: the role of TLRs and their interactions with NLRs. Semin Immunopathol 2007; 29(3):239-48.
15. Mariathasan S, Weiss DS, Dixit VM, Monack DM. Innate immunity against Francisella tularensis is dependent on the ASC/caspase-1 axis. J Exp Med 2005; 202(8):1043-9.
16. Ren T, Zamboni DS, Roy CR, Dietrich WF, Vance RE. Flagellindeficient Legionella mutants evade caspase-1-and Naip5-mediated macrophage immunity. PLoS Pathog 2006; 2(3):e18.
17. Suzuki T, Franchi L, Toma C, et al. Differential regulation of caspase-1 activation, pyroptosis, and autophagy via Ipaf and ASC in Shigellainfected macrophages. PLoS Pathog 2007; 3(8):e111.
18. Sutterwala FS, Mijares LA, Li L, Ogura Y, Kazmierczak BI, Flavell RA. Immune recognition of Pseudomonas aeruginosa mediated by the IPAF/ NLRC4 inflammasome. J Exp Med 2007; 204(13):3235-45.
19. Netea MG, Stuyt RJ, Kim SH, Van der Meer JW, Kullberg BJ, Dinarello CA. The role of endogenous interleukin (IL)-18, IL-12, IL-1-, and tumor necrosis factor- in the production of interferon- induced by Candida albicans in human whole-blood cultures. J Infect Dis 2002; 185(7):963-70.
20. Kanneganti TD, Ozören N, Body-Malapel M, et al. Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3. Nature 2006; 440(7081):233-6.
21. Franchi L, Amer A, Body-Malapel M, et al. Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1- in salmonellainfected macrophages. Nat Immunol 2006; 7(6):576-82.
22. Kuida K, Lippke JA, Ku G, et al. Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme. Science 1995; 267:2000-3.
23. Hirschfeld M, Weis JJ, Toshchakov V, et al. Signaling by Toll-like receptor 2 and 4 agonists results in differential gene expression in murine macrophages. Infect Immun 2001; 69:1477-82.
24. Gow NA, Gooday GW. Cytological aspects of dimorphism in Candida albicans. Crit Rev Microbiol 1987; 15(1):73-8.
25. Lehrer RI, Cline MJ. Interaction of Candida albicans with human leukocytes and serum. J Bacteriol 1969; 98(3):996-1004.
26. van der Graaf CA, Netea MG, Verschueren I, van der Meer JW, Kullberg BJ. Differential cytokine production and Toll-like receptor signaling pathways by Candida albicans blastoconidia and hyphae. Infect Immun 2005; 73(11):7458-64.
27. Bates S, Hughes HB, Munro CA, et al. Outer chain N-glycans are required for cell wall integrity and virulence of Candida albicans. J Biol Chem 2006; 281(1):90-8.
28. Munro CA, Bates S, Buurman ET, et al. Mnt1p and Mnt2p of Candida albicans are partially redundant-1,2-mannosyltransferases that participate in O-linked mannosylation and are required for adhesion and virulence. J Biol Chem 2005; 280(2):1051-60.
29. Hobson RP, Munro CA, Bates S, et al. Loss of cell wall mannosylphosphate in Candida albicans does not influence macrophage recognition. J Biol Chem 2004; 279(38):39628-35.
30. Bulawa CE, Miller DW, Henry LK, Becker JM. Attenuated virulence of chitin-deficient mutants of Candida albicans. Proc Natl Acad Sci USA 1995; 92(23):10570-4.
31. Netea MG, Gow NA, Munro CA, et al. Immune sensing of Candida albicans requires cooperative recognition of mannans and glucans by lectin and Toll-like receptors. J Clin Invest 2006; 116(6):1642-50.
32. Netea MG, Demacker PN, Kullberg BJ, et al. Low-density lipoprotein receptor-deficient mice are protected against lethal endotoxinemia and severe gram-negative infections. J Clin Invest 1996; 97(6):1366-72.
33. Dinarello CA, Ikejima T, Warner SJC, et al. Interleukin 1 induces interleukin 1. I. Induction of circulating interleukin 1 in rabbits in vivo and in human mononuclear cells in vitro. J Immunol 1987; 139(6):1902-10.
34. Gantner BN, Simmons RM, Underhill DM. Dectin-1 mediates macrophage recognition of Candida albicans yeast but not filaments. EMBO J 2005; 24(6):1277-86.
35. Netea MG, Van Der Graaf CA, Vonk AG, Verschueren I, Van Der Meer JW, Kullberg BJ. The role of Toll-like receptor (TLR) 2 and TLR4 in the host defense against disseminated candidiasis. J Infect Dis 2002; 185(10):1483-9.
36. Vecchiarelli A, Puliti M, Torosantucci A, Cassone A, Bistoni F. In vitro production of tumor necrosis factor by murine splenic macrophages stimulated with mannoprotein constituents of Candida albicans cell wall. Cell Immunol 1991; 134(1):65-76.
37. Jouault T, Bernigaud A, Lepage G, Trinel PA, Poulain D. The Candida albicans phospholipomannan induces in vitro production of tumour necrosis factor-alpha from human and murine macrophages. Immunology 1994; 83(2):268-73.
38. Jouault T, Lepage G, Bernigaud A, et al. Beta-1,2-linked oligomannosides from Candida albicans act as signals for tumor necrosis factor alpha production. Infect Immun 1995; 63(6):2378-81.
39. Torosantucci A, Chiani P, Cassone A. Differential chemokine response of human monocytes to yeast and hyphal forms of Candida albicans and its relation to the -1,6 glucan of the fungal cell wall. J Leukoc Biol 2000; 68(6):923-32.
40. Netea MG, Brown GD, Kullberg BJ, Gow NA. An integrated model of the recognition of Candida albicans by the innate immune system. Nat Rev Microbiol 2008; 6(1):67-78.
41. Mullin NP, Hitchen PG, Taylor ME. Mechanism of Ca2- and monosaccharide binding to a C-type carbohydrate-recognition domain of the macrophage mannose receptor. J Biol Chem 1997; 272(9):5668-81.
42. Brown GD, Herre J, Williams DL, Willment JA, Marshall AS, Gordon S. Dectin-1 mediates the biological effects of -glucans. J Exp Med 2003; 197(9):1119-24.
43. Gantner BN, Simmons RM, Canavera SJ, Akira S, Underhill DM. Collaborative induction of inflammatory responses by dectin-1 and Tolllike receptor 2. J Exp Med 2003; 197(9):1107-17.
44. Rogers NC, Slack EC, Edwards AD, et al. Syk-dependent cytokine induction by Dectin-1 reveals a novel pattern recognition pathway for C type lectins. Immunity 2005; 22(4):507-17.
45. Beutler B. Innate immunity: an overview. Mol Immunol 2004; 40(12): 845-59.
46. Franchi L, Amer A, Body-Malapel M, et al. Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1- in salmonellainfected macrophages. Nat Immunol 2006; 7(6):576-82.
47. Coeshott C, Ohnemus C, Pilyavskaya A, et al. Converting enzymeindependent release of tumor necrosis factor - and IL-1- from a stimulated human monocytic cell line in the presence of activated neutrophils or purified proteinase 3. Proc Natl Acad Sci USA 1999; 96: 6261-6.
48. Ferrari D, Pizzirani C, Adinolfi E, et al. The P2X7 receptor: a key player in IL-1 processing and release. J Immunol 2006; 176(7):3877-83.
49. Ferrari D, Chiozzi P, Falzoni S, Hanau S, Di Virgilio F. Purinergic modulation of interleukin-1- release from microglial cells stimulated with bacterial endotoxin. J Exp Med 1997; 185(3):579-82.
50. Reese TA, Liang HE, Tager AM, et al. Chitin induces accumulation in tissue of innate immune cells associated with allergy. Nature 2007; 447(7140):92-6.