Design, synthesis and evaluations of acridone derivatives using Candida albicans-Search for MDR modulators led to the identification of an anti-candidiasis agent

Bioorganic and Medicinal Chemistry

Volumn 17, Issue 11, 2009, Pages 3973-3979

  Singh, Palwinder ^a   Kaur, Jatinder ^a   Yadav, Bhawna ^b   Komath, Sneha Sudha ^b  

^a GURU NANAK DEV UNIVERSITY   (India)

^b JAWAHARLAL NEHRU UNIVERSITY   (India)

Author keywords

Acridone derivatives; Candida albicans; Cell wall rupturing; Multi drug resistance; p Glycoprotein; R6G influx efflux

Indexed keywords

10 (3 [1,4]BIPIPERIDINYL 1' YL 2 HYDROXYPROPYL) 9 OXO 9,10 DIHYDROACRIDINE 4 CARBOXYLIC ACID; ACRIDONE DERIVATIVE; ANTIFUNGAL AGENT; FLUCONAZOLE; GLYCOPROTEIN P; MICONAZOLE; UNCLASSIFIED DRUG;

ANTIFUNGAL ACTIVITY; ARTICLE; CANDIDA ALBICANS; CELL MEMBRANE PERMEABILITY; DRUG DESIGN; DRUG SYNTHESIS; MEMBRANE DAMAGE; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; STRUCTURE ACTIVITY RELATION;

ACRIDINES; ANTIFUNGAL AGENTS; CANDIDA ALBICANS; DRUG DESIGN; DRUG RESISTANCE, MULTIPLE, FUNGAL; MICROBIAL SENSITIVITY TESTS; MOLECULAR STRUCTURE; PIPERIDINES;

CANDIDA ALBICANS;

EID: 65549098645     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2009.04.026     Document Type: Article

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