Disulfiram is a potent modulator of multidrug transporter Cdr1p of Candida albicans

Biochemical and Biophysical Research Communications

Volumn 322, Issue 2, 2004, Pages 520-525

  Shukla, Suneet ^a   Sauna, Zuben E ^a   Prasad, Rajendra ^b   Ambudkar, Suresh V ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b JAWAHARLAL NEHRU UNIVERSITY   (India)

Author keywords

ABC transporter; Antifungal agents; ATP hydrolysis; Multidrug resistance; Photoaffinity labeling; Yeast

Indexed keywords

ADENOSINE TRIPHOSPHATASE; ADENOSINE TRIPHOSPHATE; ANTIFUNGAL AGENT; AZIDOPINE; CYCLOHEXIMIDE; DISULFIRAM; DITHIOTHREITOL; FLUCONAZOLE; GLYCOPROTEIN P; IODINE 125; IODOARYLAZIDOPRAZOSIN; MICONAZOLE; MULTIDRUG TRANSPORTER CDR1P; NYSTATIN; OLIGOMYCIN; PRAZOSIN; TRITIUM; UNCLASSIFIED DRUG; 8 AZIDOADENOSINE TRIPHOSPHATE; 8-AZIDOADENOSINE 5'-TRIPHOSPHATE; AZIDE; CARRIER PROTEIN; CDR1 PROTEIN, CANDIDA ALBICANS; DRUG DERIVATIVE; ENZYME INHIBITOR; FUNGAL PROTEIN; PHOSPHORUS;

ALCOHOLISM; ANIMAL CELL; ARTICLE; BINDING AFFINITY; BINDING SITE; CANDIDA ALBICANS; CONTROLLED STUDY; DRUG INHIBITION; DRUG POTENCY; DRUG SENSITIVITY; ENZYME BINDING; ENZYME INHIBITION; ENZYME SUBSTRATE COMPLEX; EXAMINATION; FUNGAL CELL; IC 50; MODULATION; NONHUMAN; PHOTOAFFINITY LABELING; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; CANDIDIASIS; DRUG EFFECT; METABOLISM; MOLECULAR CLONING; REPORTER GENE;

ANIMALIA; CANDIDA; CANDIDA ALBICANS; SACCHAROMYCES; SACCHAROMYCES CEREVISIAE;

ADENOSINE TRIPHOSPHATE; AZIDES; CANDIDA ALBICANS; CANDIDIASIS; CLONING, MOLECULAR; DISULFIRAM; ENZYME INHIBITORS; FUNGAL PROTEINS; GENES, REPORTER; MEMBRANE TRANSPORT PROTEINS; PHOSPHORUS RADIOISOTOPES; SACCHAROMYCES CEREVISIAE;

EID: 6044265703     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2004.07.151     Document Type: Article

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