Structure-activity relationships of novel N-acyloxy-1,4-dihydropyridines as P-glycoprotein inhibitors

Bioorganic and Medicinal Chemistry

Volumn 15, Issue 15, 2007, Pages 5110-5113

  Voigt, Burkhardt ^a   Coburger, Claudius ^a   Monár, Joséf ^b   Hilgeroth, Andreas ^a  

^a MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

^b UNIVERSITY OF SZEGED   (Hungary)

Author keywords

1,4 Dihydropyridines; Binding region; Multidrug resistance; P glycoprotein; Structure activity relationship

Indexed keywords

3 ACETYL 4 (2 METHOXYPHENYL) 4H PYRIDINE 1 CARBOXYLIC ACID PHENYL ESTER; 3 ACETYL 4 (4 METHOXYPHENYL) 4H PYRIDINE 1 CARBOXYLIC ACID PHENYL ESTER; 3 ACETYL 4 (4 METHYLPHENYL) 4H PYRIDINE 1 CARBOXYLIC ACID PHENYL ESTER; 3 ETHOXYCARBONYL 4 (2 METHOXYPHENYL) 4H PYRIDINE 1 CARBOXYLIC ACID PHENYL ESTER; 3 ETHOXYCARBONYL 4 (4 METHOXYPHENYL) 4H PYRIDINE 1 CARBOXYLIC ACID PHENYL ESTER; 3 ETHOXYCARBONYL 4 (4 METHYLPHENYL) 4H PYRIDINE 1 CARBOXYLIC ACID PHENYL ESTER; DIHYDROPYRIDINE DERIVATIVE; FUNCTIONAL GROUP; GLYCOPROTEIN P INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CANCER CELL; DRUG SCREENING; DRUG SYNTHESIS; IN VITRO STUDY; MOUSE; MULTIDRUG RESISTANCE; NONHUMAN; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; DIHYDROPYRIDINES; DRUG RESISTANCE, NEOPLASM; LYMPHOMA; MICE; P-GLYCOPROTEIN; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 34249939511     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2007.05.036     Document Type: Article

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