Antimalarial activity of thioacridone compounds related to the acronycine alkaloid

Bioorganic and Medicinal Chemistry

Volumn 13, Issue 5, 2005, Pages 1653-1659

  Dheyongera, James P ^a   Geldenhuys, Werner J ^b   Dekker, Theodor G ^a   Matsabisa, Motlalepula G ^c   Van Der Schyf, Cornelis J ^a,b  

^a NORTH WEST UNIVERSITY   (South Africa)

^b TEXAS TECH UNIVERSITY HEALTH SCIENCES CENTER   (United States)

^c SOUTH AFRICAN MEDICAL RESEARCH COUNCIL   (South Africa)

Author keywords

DNA intercalation; FLEXIDOCK; Malaria; MOLCAD; Plasmodium; QSAR; SYBYL; Thioacridones

Indexed keywords

1 (2 DIMETHYLAMINOETHYLAMINO) 9(10H) THIOACRIDONE; ACRIDONE DERIVATIVE; CHLOROQUINE; LACTATE DEHYDROGENASE; UNCLASSIFIED DRUG;

ANTIMALARIAL ACTIVITY; ARTICLE; BINDING SITE; CONTROLLED STUDY; DNA BINDING; DRUG POTENCY; DRUG SCREENING; HUMAN; HUMAN CELL; IC 50; LINEAR REGRESSION ANALYSIS; MALARIA; MOLECULAR INTERACTION; NONHUMAN; PLASMODIUM FALCIPARUM; QUANTITATIVE STRUCTURE ACTIVITY RELATION;

PLASMODIUM FALCIPARUM;

EID: 13444263583     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2004.12.009     Document Type: Article

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