A step toward liver gene therapy: Efficient correction of the genetic defect of hepatocytes isolated from a patient with crigler-najjar syndrome type 1 with lentiviral vectors

Transplantation

Volumn 87, Issue 7, 2009, Pages 1006-1012

  Birraux, Jacques ^a,b   Menzel, Olivier ^a   Wildhaber, Barbara ^a,b   Jond, Caty ^a   Nguyen, Tuan Huy ^b,c   Chardot, Christophe ^a,b  

^a UNIVERSITY OF GENEVA MEDICAL SCHOOL   (Switzerland)

^b UNIVERSITY OF GENEVA   (Switzerland)

^c HÔTEL DIEU   (France)

Author keywords

Cell transplantation; Crigler Najjar; Gene therapy; Lentivirus; Liver

Indexed keywords

GLUCURONOSYLTRANSFERASE 1A1; LENTIVIRUS VECTOR; BILIRUBIN URIDINE DIPHOSPHOGLUCURONOSYL TRANSFERASE 1A1; BILIRUBIN URIDINE-DIPHOSPHOGLUCURONOSYL TRANSFERASE 1A1; GLUCURONOSYLTRANSFERASE;

ANIMAL EXPERIMENT; ARTICLE; CELL ISOLATION; CELL SURVIVAL; CHILD; CONTROLLED STUDY; CRIGLER NAJJAR SYNDROME; CRIGLER NAJJAR SYNDROME TYPE 1; GENE THERAPY; GENETIC TRANSDUCTION; HEPATOCYTE TRANSPLANTATION; HUMAN; HUMAN CELL; LIVER CELL; NONHUMAN; PRESCHOOL CHILD; PRIORITY JOURNAL; PROTEIN EXPRESSION; TRANSDUCTION IN SUSPENSION WITH LENTIVIRAL VECTORS AND IMMEDIATE HEPATOCYTE TRANSPLANTATION; ANIMAL; CRYOPRESERVATION; CYTOLOGY; FEMALE; GENE VECTOR; GENETICS; LENTIVIRINAE; LIVER RESECTION; METHODOLOGY; MOUSE; MOUSE MUTANT; NONOBESE DIABETIC MOUSE; PHYSIOLOGY; TRANSPLANTATION;

ANIMALS; CHILD, PRESCHOOL; CRIGLER-NAJJAR SYNDROME; CRYOPRESERVATION; FEMALE; GENE THERAPY; GENETIC VECTORS; GLUCURONOSYLTRANSFERASE; HEPATECTOMY; HEPATOCYTES; HUMANS; LENTIVIRUS; MICE; MICE, INBRED NOD; MICE, SCID;

EID: 65549086508     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/TP.0b013e31819ca245     Document Type: Article

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