Therapeutic lentivirus-mediated neonatal in vivo gene therapy in hyperbilirubinemic Gunn rats

Molecular Therapy

Volumn 12, Issue 5, 2005, Pages 852-859

  Nguyen, Tuan Huy ^a   Bellodi Privato, Marta ^b   Aubert, Dominique ^b   Pichard, Virginie ^b   Myara, Anne ^c   Trono, Didier ^a,d   Ferry, Nicolas ^b  

^a UNIVERSITY OF GENEVA   (Switzerland)

^b HÔTEL DIEU   (France)

^c SAINT JOSEPH HOSPITAL   (France)

^d EPFL   (Switzerland)

Author keywords

Bilirubin; Crigler Najjar syndrome; Gene therapy; Glucuronosyltransferase; Gunn rat; Lentivirus

Indexed keywords

BILIRUBIN; COMPLEMENTARY DNA; GENOMIC DNA; GLUCURONOSYLTRANSFERASE 1A1; LENTIVIRUS VECTOR; LIVER ENZYME; PREALBUMIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BILE; CONTROLLED STUDY; CRIGLER NAJJAR SYNDROME; ENZYME DEFECT; FEMALE; GENETIC TRANSDUCTION; HUMAN; HUMAN CELL; HYPERBILIRUBINEMIA; IN VIVO STUDY; LIVER CELL; MALE; NEWBORN; NONHUMAN; POLYMERASE CHAIN REACTION; RAT; RAT STRAIN; TREATMENT OUTCOME; VIRAL GENE THERAPY; WESTERN BLOTTING;

ANIMALS; ANIMALS, NEWBORN; BETA-GALACTOSIDASE; BILIRUBIN; CRIGLER-NAJJAR SYNDROME; DISEASE MODELS, ANIMAL; FEMALE; GENE THERAPY; GENETIC VECTORS; GLUCURONOSYLTRANSFERASE; HEPATOCYTES; HYPERBILIRUBINEMIA; LENTIVIRUS; MALE; PLASMIDS; RATS; RATS, GUNN; TRANSDUCTION, GENETIC;

ANIMALIA; LENTIVIRUS; RATTUS NORVEGICUS;

EID: 27744501218     PISSN: 15250016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ymthe.2005.06.482     Document Type: Article

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