Amphotropic retroviral vectors displaying hepatocyte growth factor-envelope fusion proteins improve transduction efficiency of primary hepatocytes

Human Gene Therapy

Volumn 9, Issue 17, 1998, Pages 2469-2479

  Nguyen, Tuan Huy ^a   Pagès, Jean Christophe ^b   Farge, Denis ^a   Briand, Pascale ^a   Weber, Anne ^a  

^a INSTITUT COCHIN   (France)

^b GÉNÉTHON   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE ANTIBODY; HYBRID PROTEIN; SCATTER FACTOR; SCATTER FACTOR RECEPTOR; VIRUS ENVELOPE PROTEIN;

ANIMAL CELL; ARTICLE; CELL PROLIFERATION; CELL STRAIN; CONTROLLED STUDY; EXPRESSION VECTOR; GENE TARGETING; GENETIC TRANSDUCTION; LIVER CELL; MOUSE; NONHUMAN; RETROVIRUS; VIRUS INFECTION;

3T3 CELLS; ANIMALS; BASE SEQUENCE; CELL DIVISION; CELL LINE; DNA PRIMERS; DOGS; GENETIC VECTORS; HEPATOCYTE GROWTH FACTOR; LIVER; MICE; RECOMBINANT FUSION PROTEINS; RETROVIRIDAE; TRANSDUCTION, GENETIC; VIRAL ENVELOPE PROTEINS; VIRION;

ANIMALIA; MURINAE; PRIMATES; UNIDENTIFIED RETROVIRUS;

EID: 0032553651     PISSN: 10430342     EISSN: None     Source Type: Journal    
DOI: 10.1089/10430349850019319     Document Type: Article

References (33)

1. ANDREOLETTI, M., PAGÈS, J.-C., MAHIEU, D., LOUX, N., FARGE, D., SACQUIN, P., SIMON, L., HAMZA, J., BARGY, F., BRIAND, P., LEPERCQ, J., and WEBER, A. (1997). Preclinical studies for cell transplantation: Isolation of primate foetal hepatocytes, their cryopreservation, and efficient retroviral transduction. Hum. Gene Ther. 8, 267-274.
2. BATTINI, J.-L., RODRIGUES, P., MULLER, R., DANOS, O., and HEARD, J.-M. (1996). Receptor-binding properties of a purified fragment of the 4070A amphotropic murine leukemia virus envelope glycoprotein. J. Virol. 70, 4387-4393.
3. BOTTARO, D.P., RUBIN, J.S., FALETTO, D.L., CHAN, A.M., KMIECIK, T.E., VANDEWOUDE, G.F., and AARONSON, S.A. (1991). Identification of the hepatocyte growth factor receptor as the c-Met proto-oncogene product. Science 251, 802-804.
4. CHU, T.H., and DORNBURG, R. (1995). Retroviral vector particles displaying the antigen-binding site of an antibody enable cell-type-specific gene transfer. J. Virol. 69, 2659-2663.
5. CHU, T.H., MARTINEZ, I., SHEAY, W.C., and DORNBURG, R. (1994). Cell targeting with retroviral vector particles containing antibody-envelope fusion proteins. Gene Ther. 1, 292-299.
6. CHUCK, A.S., CLARKE, M.F., and PALSSON, B.O. (1996). Retroviral infection is limited by Brownian motion. Hum. Gene Ther. 7, 1527-1534.
7. COSSET, F.-L., and RUSSELL, S.J. (1996). Targeting retrovirus entry. Gene Ther. 3, 946-956.
8. COSSET, F.-L., MORLING, F.J., TAKEUCHI, Y., WEISS, R.A., COLLINS, M.K., and RUSSELL, S.J. (1995a). Retroviral retargeting by envelopes expressing an N-terminal binding domain. J. Virol. 69, 6314-6322.
9. COSSET, F.-L., TAKEUCHI, Y., BATTINI, J.-L., WEISS, R.A., and COLONS, M.K. (1995b). High-titer packaging cells producing recombinant retroviruses resistant to human serum. J. Virol. 69, 7430-7436.
10. DANOS, O., and MULLIGAN, R.C. (1988). Safe and efficient generation of recombinant retroviruses with amphotropic and ecotropic host ranges. Proc. Natl. Acad. Sci. U.S.A. 85, 6460-6464.
11. FUJIWARA, K., NAGOSHI, S., OHNO, A., HIRATA, K., OHTA, Y., MOCHIDA, S., TOMIYA, T., HIGASHIO, K., and KUROKAWA, K. (1993). Stimulation of liver growth by exogenous human hepatocyte in normal and partially hepatomized rats. Hepatology 18, 1443-1449.
12. GROSSMAN, M., RAPER, S., KOZARSKY, K., STEIN, E., ENGELHARDT, J., MULLER, D., LUPIEN, P., and WILSON, J.M. (1994). Successful ex vivo gene therapy directed to liver in a patient with familial hypercholesterolemia. Nature Genet. 6, 335-341.
13. HAN, X., KASAHARA, N., and KAN, Y.W. (1995). Ligand-directed retroviral targeting of human breast cancer cells. Proc. Natl. Acad. Sci. U.S.A. 92, 9747-9751.
14. HIGUCHI, O., and NAKAMURA, T. (1991). Identification and change in the receptor for hepatocyte growth factor in rat liver after partial hepatectomy or induced hepatitis. Biochem. Biophys. Res. Commun. 176, 599-607.
15. LIU, M.L., MARS, W.M., ZARNEGAR, R., and MICHALOPOULOS, G.K. (1994). Uptake and distribution of hepatocyte growth factor in normal and regenerating adult rat liver. Am. J. Pathol. 144, 129-140.
16. MARIN, M., NOEL, D., VALSESIA-WITTMAN, S., BROCKLY, F., ETIENNE-JULAN, S., RUSSEL, S.J., COSSET, F.-L., and PIECHACZYK, M. (1996). Targeted infection of human cells via major histocompatibility complex class I molecules by Moloney murine leukemia virus-derived viruses displaying single-chain antibody fragment-envelope fusion proteins. J. Virol. 70, 2957-2962.
17. MATSUMOTO, K., and NAKAMURA, T. (1993). Roles of HGF as a pleiotropic factor in organ regeneration. In Hepatocyte Growth Fac-tor-Scatter Factor (HGF-SF) and the c-Met Receptor. I.D. Goldberg and E.M. Rosen (eds.). (Birkhauser Verlag, Basel, Switzerland) pp. 225-249.
18. MILLER, D.G., and MILLER, A.D. (1994). Cloning of the cellular receptor for amphotropic murine viruses reveals homology to that for gibbon ape leukemia virus. Proc. Natl. Acad. Sci. U.S.A. 91, 78-82.
19. MIZUNO, K., and NAKAMURA, T. (1993). Molecular characteristics of HGF and the gene, and its biochemical aspects. In Hepatocyte growth Factor-Scatter Factor (HGF-SF) and the c-Met Receptor. I.D. Goldberg and E.M. Rosen (eds.). (Birkhauser Verlag, Basel, Switzerland) pp. 1-29.
20. MULLIGAN, R.C. (1993). The basic science of gene therapy. Science 260, 926-932.
21. NALDINI, L., WEIDNER, K.M., VINGA, E., GAUDINO, G., BARDELI, A., PONZETTO, C., NARSIMHAN, R.P., HARTMANN, G., ZARNEGAR, R., MICHALOPOULOS, G.K., BIRCHMEIER, W., and COMOGLIO, P.M. (1991). Scatter factor and hepatocyte growth factor are indistinguishable ligands for the MET receptor. EMBO J. 10, 2867-2878.
22. PAGÈS, J.-C., ANDREOLETTI, M., BENNOUN, M., VONS, C., ELCHEROTH, J., LEHN, P., HOUSSIN, D., CHAPMAN, J., BRIAND, P., BENAROUS, R., FRANCO, D., and WEBER, A. (1995). Efficient retroviral-mediated gene transfer into primary culture of murine and human hepatocytes: Expression of the LDL receptor. Hum. Gene Ther. 6, 21-30.
23. PAGÈS, J.-C., LOUX, N., BELLUSCI, S., FARGE, D., BENNOUN, M., VONS, C., JOUANNEAU, J., FRANCO, D., BRIAND, P., and WEBER, A. (1996). Hepatocyte growth factor expressed by a retrovirus-producing cell line enhances retroviral transduction of primary hepatocytes: Implications for in vivo gene transfer. Biochem. Biophys. Res. Commun. 222, 726-731.
24. RAGHEB, J.A., and ANDERSON, W.F. (1994). Uncoupled expression of Moloney murine leukemia virus envelope polypeptides SU and TM: A functional analysis of the role of TM domains in viral entry. J. Virol. 68, 3207-3219.
25. REIN, A., MIRRO, J., HAYNES, J.G., ERNST, S.M., and NAGASHIMA, K. (1994). Function of the cytoplasmic domain of a retroviral transmembrane protein: p15E-p2E cleavage activates the membrane fusion capability of the murine leukemia virus Env protein. J. Virol. 68, 1773-1781.
26. RONG, L., and BATES, P. (1995). Analysis of the subgroup A avian sarcoma and leukosis virus receptor: The 40-residue, cysteine-rich, low density lipoprotein receptor repeat motif of Tva is sufficient to mediate viral entry. J. Virol. 69, 4847-4853.
27. ROOS, F., RYAN, A.M., CHAMOW, S.M., BENNET, G.L., and SCHWALL, R.H. (1995). Induction of liver growth in normal mice by infusion of hepatocyte growth factor/scatter factor. Am. J. Physiol. 268 (2, Pt. 1), G380-G386.
28. RUSSELL, S.J., HAWKINS, R.E., and WINTER, G. (1993). Retroviral vectors displaying functional antibody fragments. Nucleic Acids Res. 21, 1081-1085.
29. SOMIA, N.V., ZOPPE, M., and VERMA, I.M. (1995). Generation of targeted retroviral vectors by using single-chain variable fragment: An approach to in vivo gene delivery. Proc. Natl. Acad. Sci. U.S.A. 92, 7570-7574.
30. VALSESIA-WITTMANN, S., DRYNDA, A., DELEAGE, G., AUMAILLEY, M., HEARD, J.-M., DANOS, O., VERDIER, G., and COSSET, F.-L. (1994). Modifications in the binding domain of avian retrovirus envelope protein to redirect the host range of retroviral vectors. J. Virol. 68, 4609-4619.
31. VALSESIA-WITTMANN, S., MORLING, F.J., NILSON, B.H., TAKEUCHI, Y., RUSSELL, S.J., and COSSET, F.-L. (1996). Improvement of retroviral retargeting by using amino acid spacers between an additional binding domain and the N-terminus of Moloney murine leukemia virus SU. J. Virol. 70, 2059-2064.
32. VALSESIA-WITTMANN, S., MORLING, F.J., HATZIOANNOU, T., RUSSELL, S.J., and COSSET, F.-L. (1997). Receptor co-operation in retrovirus entry: Recruitment of an auxiliary entry mechanism after retargeted binding. EMBO J. 16, 1214-1223.
33. WEBER-BENAROUS, A., DECAUX, J.F., BENNOUN, M., ALLEMAND, I., BRIAND, P., and KAHN, A. (1993). Retroviral infection of primary hepatocytes from normal mice and mice transgenic for SV40 large T antigen. Exp. Cell Res. 205, 91-100.