메뉴 건너뛰기




Volumn 106, Issue 5, 2009, Pages 896-902

The small GTPase RhoA is crucial for MC3T3-E1 osteoblastic cell survival

Author keywords

Apoptosis; Osteoblast; Parathyroid hormone; RhoA

Indexed keywords

4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; CASPASE 3; GERANYLGERANIOL; GERANYLTRANSFERASE; GGTI 2166; GUANOSINE TRIPHOSPHATASE; PARATHYROID HORMONE; PARATHYROID HORMONE[1-34]; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; TRANSFERASE INHIBITOR; UNCLASSIFIED DRUG;

EID: 65349136462     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.22059     Document Type: Article
Times cited : (26)

References (45)
  • 1
    • 0035836791 scopus 로고    scopus 로고
    • Rho signals to cell growth and apoptosis
    • Aznar S, Lacal JC. 2001. Rho signals to cell growth and apoptosis. Cancer Lett 165:1-10.
    • (2001) Cancer Lett , vol.165 , pp. 1-10
    • Aznar, S.1    Lacal, J.C.2
  • 3
    • 52449105081 scopus 로고    scopus 로고
    • Dense collagen matrix accelerates osteogenic differentiation and rescues the apoptotic response to MMP inhibition
    • Buxton PG, Bitar M, Gellynck K, Parkar M, Brown RA, Young AM, Knowles JC, Nazhat SN. 2008. Dense collagen matrix accelerates osteogenic differentiation and rescues the apoptotic response to MMP inhibition. Bone 43: 377-385.
    • (2008) Bone , vol.43 , pp. 377-385
    • Buxton, P.G.1    Bitar, M.2    Gellynck, K.3    Parkar, M.4    Brown, R.A.5    Young, A.M.6    Knowles, J.C.7    Nazhat, S.N.8
  • 5
    • 34447550713 scopus 로고    scopus 로고
    • Endogenous PKI gamma limits the duration of the anti-apoptotic effects of PTH and beta-adrenergic agonists in osteoblasts
    • Chen X, Song IH, Dennis JE, Greenfield EM. 2007. Endogenous PKI gamma limits the duration of the anti-apoptotic effects of PTH and beta-adrenergic agonists in osteoblasts. J Bone Miner Res 22:656-664.
    • (2007) J Bone Miner Res , vol.22 , pp. 656-664
    • Chen, X.1    Song, I.H.2    Dennis, J.E.3    Greenfield, E.M.4
  • 6
    • 0033995556 scopus 로고    scopus 로고
    • Two independent signaling pathways mediate the antiapoptotic action of macrophagestimulating protein on epithelial cells
    • Danilkovitch A, Donley S, Skeel A, Leonard EJ. 2000. Two independent signaling pathways mediate the antiapoptotic action of macrophagestimulating protein on epithelial cells. Mol Cell Biol 20:2218-2227.
    • (2000) Mol Cell Biol , vol.20 , pp. 2218-2227
    • Danilkovitch, A.1    Donley, S.2    Skeel, A.3    Leonard, E.J.4
  • 7
    • 34247200969 scopus 로고    scopus 로고
    • RhoA/Rho kinase up-regulate Bax to activate a mitochondrial death pathway and induce cardiomyocyte apoptosis
    • Del Re DP, Miyamoto S, Brown JH. 2007. RhoA/Rho kinase up-regulate Bax to activate a mitochondrial death pathway and induce cardiomyocyte apoptosis. J Biol Chem 282:8069-8078.
    • (2007) J Biol Chem , vol.282 , pp. 8069-8078
    • Del Re, D.P.1    Miyamoto, S.2    Brown, J.H.3
  • 9
    • 0032582076 scopus 로고    scopus 로고
    • Prevention of estrogen deficiency-related bone loss with human parathyroid hormone- (1-34) : A randomized controlled trial
    • Finkelstein JS, Klibanski A, Arnold AL, Toth TL, Hornstein MD, Neer RM. 1998. Prevention of estrogen deficiency-related bone loss with human parathyroid hormone- (1-34) : A randomized controlled trial. JAMA 280: 1067-1073.
    • (1998) JAMA , vol.280 , pp. 1067-1073
    • Finkelstein, J.S.1    Klibanski, A.2    Arnold, A.L.3    Toth, T.L.4    Hornstein, M.D.5    Neer, R.M.6
  • 10
    • 33749637920 scopus 로고    scopus 로고
    • RhoA GTPase inactivation by statins induces osteosarcoma cell apoptosis by inhibiting p42/p44-MAPKs-Bcl-2 signaling independently of BMP-2 and cell differentiation
    • Fromigue O, Hay E, Modrowski D, Bouvet S, Jacquel A, Auberger P, Marie PJ. 2006. RhoA GTPase inactivation by statins induces osteosarcoma cell apoptosis by inhibiting p42/p44-MAPKs-Bcl-2 signaling independently of BMP-2 and cell differentiation. Cell Death Differ 13:1845-1856.
    • (2006) Cell Death Differ , vol.13 , pp. 1845-1856
    • Fromigue, O.1    Hay, E.2    Modrowski, D.3    Bouvet, S.4    Jacquel, A.5    Auberger, P.6    Marie, P.J.7
  • 11
    • 0345826110 scopus 로고    scopus 로고
    • RhoA binds to the amino terminus of MEKK1 and regulates its kinase activity
    • Gallagher E, Gutowski S, Sternweis PC, Cobb MH. 2004. RhoA binds to the amino terminus of MEKK1 and regulates its kinase activity. J Biol Chem 279:1872-1877.
    • (2004) J Biol Chem , vol.279 , pp. 1872-1877
    • Gallagher, E.1    Gutowski, S.2    Sternweis, P.C.3    Cobb, M.H.4
  • 12
    • 0035955160 scopus 로고    scopus 로고
    • Parathyroid hormone activation of map kinase in rat duodenal cells is mediated by 3', 5'-cyclic AMP and Ca (2+)
    • Gentili C, Morelli S, Boland R, de Boland AR. 2001. Parathyroid hormone activation of map kinase in rat duodenal cells is mediated by 3', 5'-cyclic AMP and Ca (2+). Biochim Biophys Acta 1540:201-212.
    • (2001) Biochim Biophys Acta , vol.1540 , pp. 201-212
    • Gentili, C.1    Morelli, S.2    Boland, R.3    de Boland, A.R.4
  • 13
    • 0036022143 scopus 로고    scopus 로고
    • Involvement of PI3-kinase and its association with c-Src in PTH-stimulated rat enterocytes
    • Gentili C, Morelli S, Russo De Boland A. 2002. Involvement of PI3-kinase and its association with c-Src in PTH-stimulated rat enterocytes. J Cell Biochem 86:773-783.
    • (2002) J Cell Biochem , vol.86 , pp. 773-783
    • Gentili, C.1    Morelli, S.2    Russo De Boland, A.3
  • 14
    • 0037441567 scopus 로고    scopus 로고
    • Effect of ageing in the early biochemical signals elicited by PTH in intestinal cells
    • Gentili C, Picotto G, Morelli S, Boland R, de Boland AR. 2003. Effect of ageing in the early biochemical signals elicited by PTH in intestinal cells. Biochim Biophys Acta 1593:169-178.
    • (2003) Biochim Biophys Acta , vol.1593 , pp. 169-178
    • Gentili, C.1    Picotto, G.2    Morelli, S.3    Boland, R.4    de Boland, A.R.5
  • 15
    • 1842367878 scopus 로고    scopus 로고
    • Rho prevents apoptosis through Bcl-2 expression: Implications for interleukin-2 receptor signal transduction
    • Gomez J, Martinez C, Giry M, Garcia A, Rebollo A. 1997. Rho prevents apoptosis through Bcl-2 expression: Implications for interleukin-2 receptor signal transduction. Eur J Immunol 27:2793-2799.
    • (1997) Eur J Immunol , vol.27 , pp. 2793-2799
    • Gomez, J.1    Martinez, C.2    Giry, M.3    Garcia, A.4    Rebollo, A.5
  • 16
    • 0242721096 scopus 로고    scopus 로고
    • Parallel phosphatidylinositol-3 kinase and p42/44 mitogen-activated protein kinase signaling pathways subserve the mitogenic and antiapoptotic actions of insulin-like growth factor I in osteoblastic cells
    • Grey A, Chen Q, Xu X, Callon K, Cornish J. 2003. Parallel phosphatidylinositol-3 kinase and p42/44 mitogen-activated protein kinase signaling pathways subserve the mitogenic and antiapoptotic actions of insulin-like growth factor I in osteoblastic cells. Endocrinology 144:4886- 4893.
    • (2003) Endocrinology , vol.144 , pp. 4886-4893
    • Grey, A.1    Chen, Q.2    Xu, X.3    Callon, K.4    Cornish, J.5
  • 17
    • 0034641918 scopus 로고    scopus 로고
    • The biochemistry of apoptosis
    • Hengartner MO. 2000. The biochemistry of apoptosis. Nature 407:770-776.
    • (2000) Nature , vol.407 , pp. 770-776
    • Hengartner, M.O.1
  • 18
    • 0024385349 scopus 로고
    • Resorption is not essential for the stimulation of bone growth by hPTH- (1-34) in rats in vivo
    • Hock JM, Hummert JR, Boyce R, Fonseca J, Raisz LG. 1989. Resorption is not essential for the stimulation of bone growth by hPTH- (1-34) in rats in vivo. J Bone Miner Res 4:449-458.
    • (1989) J Bone Miner Res , vol.4 , pp. 449-458
    • Hock, J.M.1    Hummert, J.R.2    Boyce, R.3    Fonseca, J.4    Raisz, L.G.5
  • 19
    • 0027313988 scopus 로고
    • Early histomorphometric changes in response to parathyroid hormone therapy in osteoporosis: Evidence for de novo bone formation on quiescent cancellous surfaces
    • Hodsman AB, Steer BM. 1993. Early histomorphometric changes in response to parathyroid hormone therapy in osteoporosis: Evidence for de novo bone formation on quiescent cancellous surfaces. Bone 14:523-527.
    • (1993) Bone , vol.14 , pp. 523-527
    • Hodsman, A.B.1    Steer, B.M.2
  • 20
    • 0031024187 scopus 로고    scopus 로고
    • A randomized controlled trial to compare the efficacy of cyclical parathyroid hormone versus cyclical parathyroid hormone and sequential calcitonin to improve bone mass in postmenopausal women with osteoporosis
    • Hodsman AB, Fraher LJ, Watson PH, Ostbye T, Stitt LW, Adachi JD, Taves DH, Drost D. 1997. A randomized controlled trial to compare the efficacy of cyclical parathyroid hormone versus cyclical parathyroid hormone and sequential calcitonin to improve bone mass in postmenopausal women with osteoporosis. J Clin Endocrinol Metab 82:620-628.
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 620-628
    • Hodsman, A.B.1    Fraher, L.J.2    Watson, P.H.3    Ostbye, T.4    Stitt, L.W.5    Adachi, J.D.6    Taves, D.H.7    Drost, D.8
  • 21
    • 34248577022 scopus 로고    scopus 로고
    • Molecular and cellular mechanisms of the anabolic effect of intermittent PTH
    • Jilka RL. 2007. Molecular and cellular mechanisms of the anabolic effect of intermittent PTH. Bone 40:1434-1446.
    • (2007) Bone , vol.40 , pp. 1434-1446
    • Jilka, R.L.1
  • 22
  • 24
    • 0037564364 scopus 로고    scopus 로고
    • Distinct pathways of extracellular signalregulated kinase activation by growth factors, fibronectin and parathyroid hormone 1-34
    • Kaiser E, Chandrasekhar S. 2003. Distinct pathways of extracellular signalregulated kinase activation by growth factors, fibronectin and parathyroid hormone 1-34. Biochem Biophys Res Commun 305:573-578.
    • (2003) Biochem Biophys Res Commun , vol.305 , pp. 573-578
    • Kaiser, E.1    Chandrasekhar, S.2
  • 27
    • 0032532062 scopus 로고    scopus 로고
    • Parathyroid hormone treatment can reverse corticosteroid-induced osteoporosis. Results of a randomized controlled clinical trial
    • Lane NE, Sanchez S, Modin GW, Genant HK, Pierini E, Arnaud CD. 1998. Parathyroid hormone treatment can reverse corticosteroid-induced osteoporosis. Results of a randomized controlled clinical trial. J Clin Invest 102:1627-1633.
    • (1998) J Clin Invest , vol.102 , pp. 1627-1633
    • Lane, N.E.1    Sanchez, S.2    Modin, G.W.3    Genant, H.K.4    Pierini, E.5    Arnaud, C.D.6
  • 28
    • 0030804947 scopus 로고    scopus 로고
    • Randomised controlled study of effect of parathyroid hormone on vertebral-bone mass and fracture incidence among postmenopausal women on oestrogen with osteoporosis
    • Lindsay R, Nieves J, Formica C, Henneman E, Woelfert L, Shen V, Dempster D, Cosman F. 1997. Randomised controlled study of effect of parathyroid hormone on vertebral-bone mass and fracture incidence among postmenopausal women on oestrogen with osteoporosis. Lancet 350:550-555.
    • (1997) Lancet , vol.350 , pp. 550-555
    • Lindsay, R.1    Nieves, J.2    Formica, C.3    Henneman, E.4    Woelfert, L.5    Shen, V.6    Dempster, D.7    Cosman, F.8
  • 30
    • 33748793685 scopus 로고    scopus 로고
    • Physiological functions of caspases beyond cell death
    • Nhan TQ, Liles WC, Schwartz SM. 2006. Physiological functions of caspases beyond cell death. Am J Pathol 169:729-737.
    • (2006) Am J Pathol , vol.169 , pp. 729-737
    • Nhan, T.Q.1    Liles, W.C.2    Schwartz, S.M.3
  • 31
    • 0037294965 scopus 로고    scopus 로고
    • Fluid shear stress inhibits TNF-alpha-induced apoptosis in osteoblasts: A role for fluid shear stress-induced activation of PI3-kinase and inhibition of caspase-3
    • Pavalko FM, Gerard RL, Ponik SM, Gallagher PJ, Jin Y, Norvell SM. 2003. Fluid shear stress inhibits TNF-alpha-induced apoptosis in osteoblasts: A role for fluid shear stress-induced activation of PI3-kinase and inhibition of caspase-3. J Cell Physiol 194:194-205.
    • (2003) J Cell Physiol , vol.194 , pp. 194-205
    • Pavalko, F.M.1    Gerard, R.L.2    Ponik, S.M.3    Gallagher, P.J.4    Jin, Y.5    Norvell, S.M.6
  • 32
    • 16644383772 scopus 로고    scopus 로고
    • Rho and Rho kinase are involved in parathyroid hormone-stimulated protein kinase C alpha translocation and IL-6 promoter activity in osteoblastic cells
    • Radeff JM, Nagy Z, Stern PH. 2004. Rho and Rho kinase are involved in parathyroid hormone-stimulated protein kinase C alpha translocation and IL-6 promoter activity in osteoblastic cells. J Bone Miner Res 19:1882- 1891.
    • (2004) J Bone Miner Res , vol.19 , pp. 1882-1891
    • Radeff, J.M.1    Nagy, Z.2    Stern, P.H.3
  • 33
    • 3042549659 scopus 로고    scopus 로고
    • RhoA controls myoblast survival by inducing the phosphatidylinositol 3-kinase-Akt signaling pathway
    • Reuveny M, Heller H, Bengal E. 2004. RhoA controls myoblast survival by inducing the phosphatidylinositol 3-kinase-Akt signaling pathway. FEBS Lett 569:129-134.
    • (2004) FEBS Lett , vol.569 , pp. 129-134
    • Reuveny, M.1    Heller, H.2    Bengal, E.3
  • 34
    • 33746383082 scopus 로고    scopus 로고
    • Diverse antiapoptotic signaling pathways activated by vasoactive intestinal polypeptide, epidermal growth factor, and phosphatidylinositol 3-kinase in prostate cancer cells converge on BAD
    • Sastry KS, Smith AJ, Karpova Y, Datta SR, Kulik G. 2006. Diverse antiapoptotic signaling pathways activated by vasoactive intestinal polypeptide, epidermal growth factor, and phosphatidylinositol 3-kinase in prostate cancer cells converge on BAD. J Biol Chem 281:20891- 20901.
    • (2006) J Biol Chem , vol.281 , pp. 20891-20901
    • Sastry, K.S.1    Smith, A.J.2    Karpova, Y.3    Datta, S.R.4    Kulik, G.5
  • 35
    • 0346101793 scopus 로고    scopus 로고
    • Parathyroid hormone-Smad3 axis exerts anti-apoptotic action and augments anabolic action of transforming growth factor beta in osteoblasts
    • Sowa H, Kaji H, Iu MF, Tsukamoto T, Sugimoto T, Chihara K. 2003. Parathyroid hormone-Smad3 axis exerts anti-apoptotic action and augments anabolic action of transforming growth factor beta in osteoblasts. J Biol Chem 278:52240-52252.
    • (2003) J Biol Chem , vol.278 , pp. 52240-52252
    • Sowa, H.1    Kaji, H.2    Iu, M.F.3    Tsukamoto, T.4    Sugimoto, T.5    Chihara, K.6
  • 37
    • 0035831498 scopus 로고    scopus 로고
    • Stimulation of extracellular signal-regulated kinases and proliferation in rat osteoblastic cells by parathyroid hormone is protein kinase C-dependent
    • Swarthout JT, Doggett TA, Lemker JL, Partridge NC. 2001. Stimulation of extracellular signal-regulated kinases and proliferation in rat osteoblastic cells by parathyroid hormone is protein kinase C-dependent. J Biol Chem 276:7586-7592.
    • (2001) J Biol Chem , vol.276 , pp. 7586-7592
    • Swarthout, J.T.1    Doggett, T.A.2    Lemker, J.L.3    Partridge, N.C.4
  • 38
    • 0037045407 scopus 로고    scopus 로고
    • Parathyroid hormone-dependent signaling pathways regulating genes in bone cells
    • Swarthout JT, D'Alonzo RC, Selvamurugan N, Partridge NC. 2002. Parathyroid hormone-dependent signaling pathways regulating genes in bone cells. Gene 282:1-17.
    • (2002) Gene , vol.282 , pp. 1-17
    • Swarthout, J.T.1    D'Alonzo, R.C.2    Selvamurugan, N.3    Partridge, N.C.4
  • 40
    • 28544437352 scopus 로고    scopus 로고
    • Growth factors and antiapoptotic signaling pathways in multiple myeloma
    • van de Donk NW, Lokhorst HM, Bloem AC. 2005. Growth factors and antiapoptotic signaling pathways in multiple myeloma. Leukemia 19: 2177-2185.
    • (2005) Leukemia , vol.19 , pp. 2177-2185
    • van de Donk, N.W.1    Lokhorst, H.M.2    Bloem, A.C.3
  • 41
    • 33846826885 scopus 로고    scopus 로고
    • Endothelin signaling in osteoblasts: Global genome view and implication of the calcineurin/NFAT pathway
    • Van Sant C, Wang G, Anderson MG, Trask OJ, Lesniewski R, Semizarov D. 2007. Endothelin signaling in osteoblasts: Global genome view and implication of the calcineurin/NFAT pathway. Mol Cancer Ther 6:253-261.
    • (2007) Mol Cancer Ther , vol.6 , pp. 253-261
    • Van Sant, C.1    Wang, G.2    Anderson, M.G.3    Trask, O.J.4    Lesniewski, R.5    Semizarov, D.6
  • 42
    • 33846855997 scopus 로고    scopus 로고
    • Effects of transient PTH on early proliferation, apoptosis, and subsequent differentiation of osteoblast in primary osteoblast cultures
    • Wang YH, Liu Y, Rowe DW. 2007. Effects of transient PTH on early proliferation, apoptosis, and subsequent differentiation of osteoblast in primary osteoblast cultures. Am J Physiol Endocrinol Metab 292:E594-E603.
    • (2007) Am J Physiol Endocrinol Metab , vol.292
    • Wang, Y.H.1    Liu, Y.2    Rowe, D.W.3
  • 43
    • 0041767267 scopus 로고    scopus 로고
    • Mechanical control of human osteoblast apoptosis and proliferation in relation to differentiation
    • Weyts FA, Bosmans B, Niesing R, van Leeuwen JP, Weinans H. 2003. Mechanical control of human osteoblast apoptosis and proliferation in relation to differentiation. Calcif Tissue Int 72:505-512.
    • (2003) Calcif Tissue Int , vol.72 , pp. 505-512
    • Weyts, F.A.1    Bosmans, B.2    Niesing, R.3    van Leeuwen, J.P.4    Weinans, H.5
  • 44
    • 33646710125 scopus 로고    scopus 로고
    • Constitutively active alpha subunits of G (q /11) and G (12/13) families inhibit activation of the pro-survival Akt signaling cascade
    • Wu EH, TamBH, Wong YH. 2006. Constitutively active alpha subunits of G (q /11) and G (12/13) families inhibit activation of the pro-survival Akt signaling cascade. FEBS J 273:2388-2398.
    • (2006) FEBS J , vol.273 , pp. 2388-2398
    • Wu, E.H.1    Tam, B.H.2    Wong, Y.H.3
  • 45
    • 40449087736 scopus 로고    scopus 로고
    • RhoA prevents apoptosis during zebrafish embryogenesis through activation of Mek/Erk pathway
    • Zhu S, Korzh V, Gong Z, Low BC. 2008. RhoA prevents apoptosis during zebrafish embryogenesis through activation of Mek/Erk pathway. Oncogene 27:1580-1589.
    • (2008) Oncogene , vol.27 , pp. 1580-1589
    • Zhu, S.1    Korzh, V.2    Gong, Z.3    Low, B.C.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.