RhoA Binds to the Amino Terminus of MEKK1 and Regulates Its Kinase Activity

Journal of Biological Chemistry

Volumn 279, Issue 3, 2004, Pages 1872-1877

  Gallagher, Ewen D ^a,b   Gutowski, Stephen ^a   Sternweis, Paul C ^a   Cobb, Melanie H ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b San Diego   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYMES; MODIFICATION; PROTEINS;

AMINO-TERMINAL DOMAIN;

BIOCHEMISTRY;

CYSTEINE; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE KINASE; PROTEIN CDC42; RAC PROTEIN; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; RHO GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; ENZYME ACTIVITY; ENZYME MODIFICATION; ENZYME REGULATION; HUMAN; HUMAN CELL; MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; UBIQUITINATION;

AMINO ACID SEQUENCE; ANIMALS; CDC42 GTP-BINDING PROTEIN; CELLS, CULTURED; DOGS; HUMANS; MAP KINASE KINASE KINASE 1; MAP KINASE KINASE KINASES; MOLECULAR SEQUENCE DATA; RAC1 GTP-BINDING PROTEIN; RHOA GTP-BINDING PROTEIN; UBIQUITIN;

ANIMALIA;

EID: 0345826110     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M309525200     Document Type: Article

References (48)

1. Karin, M., and Delhase, M. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 9067-9069
2. Pearson, G., Robinson, F., Beers, G. T., Xu, B., Karandikar, M., Berman, K., and Cobb, M. H. (2001) Endocr. Rev. 22, 153-183
3. Lin, A., Minden, A., Martinetto, H., Claret, F.-X., Lange-Carter, C., Mercurio, F., Johnson, G., and Karin, M. (1995) Science 268, 286-290
4. Xu, S., Robbins, D., Frost, J., Dang, A., Lange-Carter, C., and Cobb, M. H. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 6808-6812
5. Lee, F. S., Hagler, J., Chen, Z. J., and Maniatis, T. (1997) Cell 88, 213-222
6. Yin, M. J., Christerson, L. B., Yamamoto, Y., Kwak, Y. T., Xu, S., Mercurio, F., Barbosa, M., Cobb, M. H., and Gaynor, R. B. (1998) Cell 93, 875-884
7. Yujiri, T., Sather, S., Fanger, G. R., and Johnson, G. L. (1998) Science 282, 1911-1914
8. Xia, Y., Makris, C., Su, B., Li, E., Yang, J., Nemerow, G. R., and Karin, M. (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 5243-5248
9. Lange-Carter, C. A., Pleiman, C. M., Gardner, A. M., Blumer, K. J., and Johnson, G. L. (1993) Science 260, 315-319
10. Xu, S., Robbins, D. J., Christerson, L. B., English, J. M., Vanderbilt, C. A., and Cobb, M. H. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 5291-5295
11. Blank, J. L., Gerwins, P., Elliott, E. M., Sather, S., and Johnson, G. L. (1996) J. Biol. Chem. 271, 5361-5368
12. Gerwins, P., Blank, J. L., and Johnson, G. L. (1997) J. Biol. Chem. 272, 8288-8295
13. Bonvin, C., Guillon, A., van Bemmelen, M. X., Gerwins, P., Johnson, G. L., and Widmann, C. (2002) Cell Signal. 14, 123-131
14. Xu, S., and Cobb, M. H. (1997) J. Biol. Chem. 272, 32056-32060
15. Xia, Y., Wu, Z., Su, B., Murray, B., and Karin, M. (1998) Genes Dev. 12, 3369-3381
16. Karandikar, M., Xu, S., and Cobb, M. H. (2000) J. Biol. Chem. 275, 40120-40127
17. Su, Y.-C., Han, J., Xu, S., Cobb, M., and Skolnik, E. Y. (1997) EMBO J. 16, 1279-1290
18. Chadee, D. N., Yuasa, T., and Kyriakis, J. M. (2002) Mol. Cell. Biol. 22, 737-749
19. Choi, K.-Y., Satterberg, B., Lyons, D. M., and Elion, E. A. (1994) Cell 78, 499-512
20. Marcus, S., Polverino, A., Barr, M., and Wigler, M. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 7762-7766
21. Printen, J. A., and Sprague, G. F. J. (1994) Genetics 138, 609-619
22. Lu, Z., Xu, S., Joazeiro, C., Cobb, M. H., and Hunter, T. (2002) Mol. Cell 9, 945-956
23. Christerson, L. B., Vanderbilt, C. A., and Cobb, M. H. (1999) Cell Motil. Cytoskeleton 43, 186-198
24. Fanger, G. R., Widmann, C., Porter, A. C., Sather, S., Johnson, G. L., and Vaillancourt, R. R. (1998) J. Biol. Chem. 273, 3476-3483
25. Russell, M., Lange-Carter, C. A., and Johnson, G. L. (1995) J. Biol. Chem. 270, 11757-11760
26. Fanger, G. R., Johnson, N. L., and Johnson, G. L. (1997) EMBO J. 16, 4961-4972
27. Bar-Sagi, D., and Hall, A. (2000) Cell 103, 227-238
28. Ridley, A. J., Paterson, H. F., Johnson, C. L., Diekmann, D., and Hall, A. (1992) Cell 70, 401-410
29. Yujiri, T., Ware, M., Widmann, C., Oyer, R., Russell, D., Chan, E., Zaitsu, Y., Clarke, P., Tyler, K., Oka, Y., Fanger, G. R., Henson, P., and Johnson, G. L. (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 7272-7277
30. Yujiri, T., Fanger, G. R., Garrington, T. P., Schlesinger, T. K., Gibson, S., and Johnson, G. L. (1999) J. Biol. Chem. 274, 12605-12610
31. Schlesinger, T. K., Bonvin, C., Jarpe, M. N., Fanger, G. R., Cardinaux, J. R., Johnson, G. L., and Widmann, C. (2002) J. Biol. Chem.
32. Christerson, L. B., Gallagher, E., Vanderbilt, C. A., Whitehurst, A. W., Wells, C., Kazempour, R., Sternweis, P. C., and Cobb, M. H. (2002) J. Cell. Physiol. 192, 200-208
33. Gallagher, E. D., Xu, S., Moomaw, C., Slaughter, C. A., and Cobb, M. H. (2002) J. Biol. Chem. 277, 45785-45792
34. Kozasa, T., Jiang, X., Hart, M. J., Sternweis, P. M., Singer, W. D., Gilman, A. G., Bollag, G., and Sternweis, P. C. (1998) Science 280, 2109-2111
35. Sambrook, J., Fritsch, E. F., and Maniatis, T. (1989) Molecular Cloning: A Laboratory Manual, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
36. Deng, L., Wang, C., Spencer, E., Yang, L., Braun, A., You, J., Slaughter, C., Pickart, C., and Chen, Z. J. (2000) Cell 103, 351-361
37. Xu, B., English, J. M., Wilsbacher, J. L., Stippec, S., Goldsmith, E. J., and Cobb, M. H. (2000) J. Biol. Chem. 275, 16795-16801
38. Burbelo, P. D., Drechsel, D., and Hall, A. (1995) J. Biol. Chem. 270, 29071-29074
39. Fujisawa, K., Fujita, A., Ishizaki, T., Saito, Y., and Narumiya, S. (1996) J. Biol. Chem. 271, 23022-23028
40. Reid, T., Furuyashiki, T., Ishizaki, T., Watanabe, G., Watanabe, N., Fujisawa, K., Morii, N., Madaule, P., and Narumiya, S. (1996) J. Biol. Chem. 271, 13556-13560
41. Vincent, S., and Settleman, J. (1997) Mol. Cell. Biol. 17, 2247-2256
42. Moodie, S. A., Willumsen, B. M., Weber, M. J., and Wolfman, A. (1993) Science 260, 1658-1660
43. Vojtek, A. B., Hollenberg, S. M., and Cooper, J. A. (1993) Cell 74, 205-214
44. Matsui, T., Amano, M., Yamamoto, T., Chihara, K., Nakafuku, M., Ito, M., Nakano, T., Okawa, K., Iwamatsu, A., and Kaibuchi, K. (1996) EMBO J. 15, 2208-2216
45. Leung, T., Chen, Q., Manser, E., and Lim, L. (1996) Mol. Cell. Biol. 5313-5327
46. Manser, E., Leung, T., Salihuddin, H., Zhao, Z.-S., and Lim, L. (1994) Nature 367, 40-46
47. Frost, J. A., Khokhlatchev, A., White, M. A., and Cobb, M. H. (1998) J. Biol. Chem. 273, 28253-28260
48. Sotiropoulos, A., Gineitis, D., Copeland, J., and Treisman, R. (1999) Cell 98, 159-169