Induction of cell cornification and enhanced squamous-cell marker SPRR1 gene expression by phorbol ester are regulated by different signaling pathways in human conducting airway epithelial cells

American Journal of Respiratory Cell and Molecular Biology

Volumn 22, Issue 5, 2000, Pages 597-603

  Deng, Jun ^a   Chen, Yin ^a   Wu, Reen ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0034029899     PISSN: 10441549     EISSN: None     Source Type: Journal    
DOI: 10.1165/ajrcmb.22.5.3520     Document Type: Article

References (39)

1. 1. Becci, P. J., E. M. McDowell, and B. F. Trump. 1978. The respiratory epithelium: IV. Histogenesis of epidermoid metaplasia and carcinoma in situ in the hamster. J. Natl. Cancer Res. 61:577-586.
2. 2. Chopra, D. P. 1982. Sqnamous metaplasia in organ cultures of vitamin A deficient hamster trachea: cytokinetic and ultrastructural alterations. J. Natl. Cancer Inst. 69:895-905.
3. 3. Wong, Y. C., and R. C. Buck. 1971. An electron microscopic study of metaplasia of the rat tracheal epithelium in vitamin A deficiency, Lab. Invest. 24:55-66.
4. 4. Nasiell, M. 1966. Metaplasia and atypical metaplasia in the bronchial epithelium: a histopathologic and cytopathologic study. Acta Cytol. 10:421-427.
5. 5. Nasiell, M., H. Kato, G. Auer, A. Zetterberg, V. Roger, and L. Karlen. 1978. Cytomorphological grading and Feulgen DNA analysis of metaplastic and neoplastic bronchial cells. Cancer 41:1511-1521.
6. 6. Jetten, A. M. 1989. Multistep process of squamous differentiation in tracheobronchial epithelial cells in vitro: analogy with epidermal differentiation. Environ. Health Perspect. 80:149-160.
7. 7. Tesfaigzi, J., J. Thing, J. A. Hotchkiss, J. R. Harkema, and P. S. Wright. 1996. A small proline-rich protein, SPRR1, is upregulated early during tobacco smoke-induced squamous metaplasia in rat nasal epithelia. Am. J. Respir. Cell Mol. Biol. 14:478-486.
8. 8. Reichert, U., S. Michel, and M. Schmidt. 1993. The cornified envelope: a key structure of terminal differentiating keratinocytes. In Molecular Biology of the Skin. M. Dermon and M. Blumenberg, editors. Academic Press, New York. 151-179.
9. 9. Willey, J. C., A. J. Saladino, C. Ozanne, J. F. Lechner, and C. C. Harris. 1984. Acute effects of 12-O-tetracanoylphorbol-13-acetate, teleocidin B, or 2,3,7.8-tetrachlorodibenzo-p-dioxin on cultured normal human bronchial epithelial cells. Carcinogenesis 5:209-215.
10. 10. Matsui, M. S., I. Illarda, N. Wang, and V. A. DeLeo. 1993. Protein kinase C agonist and antagonist effects in normal human epidermal keratinocytes. Exp. Dermatol. 2:247-256.
11. 11. An, G., J. Tesfaigzi, Y. J. Chuu, and R. Wu. 1993. Isolation and characterization of the human spr1 gene and its regulation of expression by phorbol ester and cyclic AMP. J. Biol. Chem. 268:10977-10982.
12. 12. Reddy, P. M. S., Y. J. Chuu, P. N. Lao, J. Donn, D. K. Ann, and R. Wu. 1995. Expression of human squamous-cell differentiation marker, SPR1, in tracheobronchial epithelium depends on JUN and TRE motifs. J. Biol. Chem. 270:26451-26459.
13. 13. Gschwendt, M., W. Kittstein, and F. Marks. 1991. Protein kinase C activation by phorbol esters: do cysteine-rich regions and pseudosubstrate motifs play a role? TIBS 16:167-169.
14. 14. Blobe, G. C., S. Sloan, L. M. Obeid, and Y. A. Hannun. 1996. Protein kinase C isoenzymes: regulation and function. Cell. Signal. 27:213-248.
15. 15. Blumer, K. J., and G. L. Johnson. 1994. Diversity in function and regulation of MAP kinase pathways. Trends. Biochem. Sci. 19:236-240.
16. 16. Seger, R., and E. G. Krebs. 1995. The MAPK signaling cascade. FASEB J. 9:726-735.
17. 17. Boulton, T. G., S. H. Nye, D. J. Robbins, N. Y. Ip. E. Radziejewska, S. D. Morgenbesser, R. A. DePinho, N. Panayotatos, M. H. Cobb, and G. D. Yancopoulos. 1991. ERKs: a family of protein-serine/threonine kinases that are activated and tyrosine phosphorylated in response to insulin and NGF. Cell 65:663-675.
18. 18. Derrijard, B., M. Hibi, I. H. Wu, T. Barren, B. Su, T. Deng, M. Karin, and R. J. Davis. 1994. JUKI: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain. Cell 76: 1025-1037.
19. 19. Han, J., J. D. Lee, L. Bibbs, and R. J. Ulevitch. 1994. A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells. Science 265: 808-811.
20. 20. Nishida, E., and Y. Gotoh. 1993. The MAP kinase cascade is essential for diverse signal transduction pathways. Trends Biochem. Sci. 18:128-131.
21. 21. Davis, R. J. 1993. The mitogen-activated protein kinase signal transduction pathway. J. Biol. Chem. 268:14553-14556.
22. 22. Catling, A. D., C. W. Reuter, M. E. Cox, S. J. Parsons, and M. J. Weber. 1994. Partial purification of a mitogen-activated protein kinase activator from bovine brain: identification as B-Raf-associatcd activity. J. Biol. Chem. 269:30014-30021.
23. 23. Kyriakis, J. M., H. App, X. F. Zhang, P. Banerjee, D. L. Brautigan, U. R. Rapp. and J. Avruch. 1992. Raf-1 activates MAP kinase-kinase. Nature 358:417-421.
24. 24. Vaillancourt, R. R., A. M. Gardner, and G. L. Johnson. 1994. B-Raf-dependent regulation of the MEK-1/mitogen-activated protein kinase pathway in PC12 cells and regulation by cyclic AMP. Mol. Cell Biol. 14:6522-6530.
25. 25. Reuter, C. W., A. D. Catling, T. Jelinek, and M. J. Weber. 1995. Biochemical analysis of MEK activation in NIH3T3 fibroblasts: identification of B-Raf and other activators. J. Biol. Chem. 270:7644-7655.
26. 26. Gulbins, E., K. M. Coggeshall, G. Baier, D. Telford, C. Langlet, G. Baier-Bitterlich, N. Bonnefoy-Berard, P. Burn, A. Wittinghofer, and A. Altman. 1994. Direct stimulation of Vav guanine nucleotide exchange activity for Ras by phorbol esters and diglycerides. Mol. Cell Biol. 14:4749-4758.
27. 27. Ahmed, S., J. Lee, R. Kozma, A. Best, C. Monfries, and L. Lim. 1993. A novel functional target for tumor-promoting phorbol esters and lysophosphatidic acid: the p21rac-GTPase activating protein n-chimaerin. J. Biol. Chem. 268:10709-10712.
28. 28. Rossomando, A. J., D. M. Payne, M. J. Weber, and T. W. Sturgill. 1989. Evidence that p42, a major lyrosine target protein, is a mitogen-activated serine/threonine protein kinase. Proc. Natl. Acad. Sci. USA 86:6940-6943.
29. 29. Seger, R., Y. Beiner, R. Feinstein, T. Hanoch, A. Gazit, and Y. Zick. 1995. Differential activation of mitogen-activated protein kinase and S6 kinase signaling pathways by 12-o-tetradecanoylphorbol-13-acetate (TPA) and insulin: evidence for involvement of a TPA-stimulated protein-tyrosine kinase. J. Biol. Chem. 270:28325-28330.
30. 30. Ueda, Y., S. I. Hirai, S. I. Osada, A. Suzuki, K. Mizuno, and S. Ohno. 1996. Protein kinase C δ activates the MEK-ERK pathway in a manner independent of Ras and dependent on Raf. J. Biol. Chem. 271:23512-23519.
31. 31. Wu, R., J. W. Groelke, L. Y. Chang, M. E. Porter, D. Smith, and P. Nettesheim. 1982. Effects of hormones on the multiplication and differentiation of tracheal epithelial cells in culture. In Growth of Cells in Hormonally Defined Media. D. Sirbasku, G. H. Sato, and A. Pardee, editors. Cold Spring Harbor Laboratory, Cold Spring Harbor, New York. 641-656.
32. 32. Robinson, C. B., and R. Wu. 1991. Culture of conducting airway epithelial cells in serum-free medium. J. Tissue Cult. Method 13:95-102.
33. 33. Jetten, A. M., and H. Smits. 1985. Regulation of differentiation of tracheal epithelial cells by retinoids. In Retinoids, Differentiation and Disease (Ciba Foundation Symposium). Pitman, London. 61-76.
34. 34. Chomczynski, P., and N. Sacchi. 1987. Single-step of RNA isolation by acid guanidiniumthiocyanate-phenol-chloroform extraction. Anal. Biochem. 162:1546-1549.
35. 35. Huang, T. H., J. A. St. George, C. G. Plopper, and R. Wu. 1989. Keratin protein expression during the development of conducting airway epithelium in nonhuman primates. Differentiation 41:78-86.
36. 36. Schultz, H., K. Engel, and M. Gaestel. 1997. PMA-induced activation of the p42/44-ERK-and p38RK MAP kinase cascades in HL-60 cells is PKC dependent but not essential for differentiation to the macrophage-like phenotype. J. Cell. Physiol. 173:310-318.
37. 37. Guan, K. L. 1994. The mitogen activated protein kinase signal transduction pathway: from cell surface to the nucleus. Cell. Signal. 6:581-589
38. 38. Stadheim, T. A., and G. L. Kucera. 1998. Extracellular signal regulated kinase (ERK) activity is required for TPA-mediated inhibition of drug-induced apoptosis. Biochem. Biophys. Res. Commun. 245:266-271.
39. 39. Pang, L., T. Sawada, S. J. Decker, and A. R. Salteil. 1995. Inhibition of MAP kinase kinase blocks the differentiation of PC-12 cells induced by nerve growth factor. J. Biol. Chem. 270:13585-13588.