Novel zinc finger nuclease created by combining the Cys2His2- and His4-type zinc finger domains

Bioorganic and Medicinal Chemistry Letters

Volumn 19, Issue 10, 2009, Pages 2789-2791

  Negi, Shigeru ^a   Umeda, Yoshiyuki ^b   Masuyama, Saeko ^a   Kano, Koji ^b   Sugiura, Yukio ^a  

^a DOSHISHA WOMEN'S COLLEGE OF LIBERAL ARTS   (Japan)

^b DOSHISHA UNIVERSITY   (Japan)

Author keywords

DNA binding; DNA cleavage; His4 type zinc finger domain; Zinc finger nuclease; Zinc finger protein, DNA binding

Indexed keywords

CYSTEINE; DOUBLE STRANDED DNA; HISTIDINE; NUCLEASE; TRANSCRIPTION FACTOR SP1; ZINC; ZINC FINGER PROTEIN;

ARTICLE; BINDING AFFINITY; BINDING SITE; CIRCULAR DICHROISM; DNA BASE COMPOSITION; ENZYME SYNTHESIS; GEL MOBILITY SHIFT ASSAY; HYDROLYSIS; PROTEIN DNA BINDING; PROTEIN FOLDING; PROTEIN SECONDARY STRUCTURE; ZINC FINGER MOTIF;

AMINO ACID SEQUENCE; BINDING SITES; CIRCULAR DICHROISM; ENDONUCLEASES; MOLECULAR SEQUENCE DATA; MUTATION; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; SP1 TRANSCRIPTION FACTOR; ZINC FINGERS;

EID: 65349114893     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2009.03.088     Document Type: Article

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