Differential proteomic analysis of lymphocytes treated with mycophenolic acid reveals caspase 3-induced cleavage of rho gdp dissociation inhibitor 2

Therapeutic Drug Monitoring

Volumn 31, Issue 2, 2009, Pages 211-217

  Heller, Tanja ^a   Asif, Abdul R ^a   Petrova, Darinka Todorova ^a   Doncheva, Yuliana ^a   Wieland, E ^b   Oellerich, Michael ^a   Shipkova, Maria ^b   Armstrong, Victor William ^a  

^a UNIVERSITY MEDICAL CENTER GÖTTINGEN   (Germany)

^b KLINIKUM STUTTGART   (Germany)

Author keywords

Mass spectrometry; Mycophenolic acid; Pharmacoproteomics; Rho GDP dissociation inhibitor 2

Indexed keywords

ARGININE; CASPASE 3; COFILIN 1; CYCLINE; DEOXYURIDINE 5' TRIPHOSPHATE NUCLEOTIDOHYDROLASE; ENDOPLASMIN; IONOMYCIN; ISOMERASE; LEUCINE; MYCOPHENOLIC ACID; PEPTIDYL PROLYL ISOMERASE A; PHORBOL 13 ACETATE 12 MYRISTATE; PHOSPHOPROTEIN; PHOSPHOPROTEIN 32 FAMILY MEMBER A; PROSTAGLANDIN E SYNTHASE; PROSTAGLANDIN E SYNTHASE 3; RHO GUANOSINE DIPHOSPHATE DISSOCIATION INHIBITOR 2; RHO KINASE; SERINE; UNCLASSIFIED DRUG; ARHGDIB PROTEIN, HUMAN; GUANINE NUCLEOTIDE DISSOCIATION INHIBITOR; IMMUNOSUPPRESSIVE AGENT; PROTEOME; TUMOR SUPPRESSOR PROTEIN;

AMINO ACID SEQUENCE; ARTICLE; CELL FUNCTION; CELL MOTILITY; CELL PROLIFERATION; CONTROLLED STUDY; CYTOSKELETON; DENSITOMETRY; DRUG MECHANISM; ELECTROPHORESIS; HUMAN; HUMAN CELL; LYMPHOCYTE; MOLECULAR WEIGHT; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEOMICS; T LYMPHOBLAST; WESTERN BLOTTING; CELL CULTURE; DOSE RESPONSE; DRUG EFFECT; METABOLISM;

CASPASE 3; CELL PROLIFERATION; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; GUANINE NUCLEOTIDE DISSOCIATION INHIBITORS; HUMANS; IMMUNOSUPPRESSIVE AGENTS; LYMPHOCYTES; MYCOPHENOLIC ACID; PROTEOME; TUMOR SUPPRESSOR PROTEINS;

EID: 65349089391     PISSN: 01634356     EISSN: 15363694     Source Type: Journal    
DOI: 10.1097/FTD.0b013e318196fb73     Document Type: Article

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