Inhibition of ICMT induces endothelial cell apoptosis through GRP94

American Journal of Respiratory Cell and Molecular Biology

Volumn 37, Issue 1, 2007, Pages 20-30

  Lu, Qing ^b   Harrington, Elizabeth O ^b   Newton, Julie ^b   Jankowich, Matthew ^b   Rounds, Sharon ^a  

^a PROVIDENCE VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b NONE

Author keywords

Apoptosis; GRP94; ICMT; RhoA GTPase; Unfolded protein response

Indexed keywords

CALNEXIN; CASPASE; CYSTEINE DERIVATIVE; ENZYME INHIBITOR; GLUCOSE REGULATED PROTEIN 94; N ACETYLGERANYLGERANYLCYSTEINE; PROTEIN S ISOPRENYLCYSTEINE O METHYLTRANSFERASE; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; ENDOTHELIUM CELL; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOFLUORESCENCE; ISOELECTRIC POINT; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN AGGREGATION; PROTEIN ANALYSIS; PROTEIN CONTENT; PROTEIN DEGRADATION; PROTEIN LOCALIZATION; PROTEIN TRANSPORT; PROTEOMICS;

ANIMALS; APOPTOSIS; CATTLE; CELLS, CULTURED; CYSTEINE; DITERPENES; ENDOTHELIAL CELLS; ENZYME INHIBITORS; HUMANS; HYDROGEN-ION CONCENTRATION; ISOELECTRIC POINT; MEMBRANE GLYCOPROTEINS; PROTEIN DENATURATION; PROTEIN METHYLTRANSFERASES; PULMONARY ARTERY; RHOA GTP-BINDING PROTEIN;

EID: 34347261719     PISSN: 10441549     EISSN: None     Source Type: Journal    
DOI: 10.1165/rcmb.2006-0301SM     Document Type: Article

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