메뉴 건너뛰기




Volumn 28, Issue 2, 2006, Pages 145-154

Therapeutic drug monitoring of mycophenolate mofetil in transplantation

(12)  Van Gelder, Teun a   Meur, Yann Le b   Shaw, Leslie M c   Oellerich, Michael d   DeNofrio, David e   Holt, Curtis f   Holt, David W g   Kaplan, Bruce h   Kuypers, Dirk i   Meiser, Bruno j   Toenshoff, Burkhard k   Mamelok, Richard D l  


Author keywords

Mycophenolate mofetil; Therapeutic drug monitoring; Transplantation

Indexed keywords

CYCLOSPORIN; IMMUNOSUPPRESSIVE AGENT; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; TACROLIMUS;

EID: 33745957413     PISSN: 01634356     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.ftd.0000199358.80013.bd     Document Type: Review
Times cited : (302)

References (75)
  • 1
    • 0034897144 scopus 로고    scopus 로고
    • Current issues in therapeutic drug monitoring of mycophenolic acid: Report of a roundtable discussion
    • Shaw LM, Holt DW, Oellerich M, et al. Current issues in therapeutic drug monitoring of mycophenolic acid: report of a roundtable discussion. Ther Drug Monit. 2001;23:305-315.
    • (2001) Ther Drug Monit , vol.23 , pp. 305-315
    • Shaw, L.M.1    Holt, D.W.2    Oellerich, M.3
  • 2
    • 16244403301 scopus 로고    scopus 로고
    • Immunosuppression: Evolution in practice and trends, 1993-2003
    • Shapiro R, Young JB, Milford EL, et al. Immunosuppression: evolution in practice and trends, 1993-2003. Am J Transplant. 2005;5:874-886.
    • (2005) Am J Transplant , vol.5 , pp. 874-886
    • Shapiro, R.1    Young, J.B.2    Milford, E.L.3
  • 4
    • 0029006409 scopus 로고
    • Placebo-controlled study of mycophenolate mofetil combined with cyclosporin and corticosteroids for prevention of acute rejection
    • European Mycophenolate Mofetil Cooperative Study Group
    • European Mycophenolate Mofetil Cooperative Study Group. Placebo-controlled study of mycophenolate mofetil combined with cyclosporin and corticosteroids for prevention of acute rejection. European Mycophenolate Mofetil Cooperative Study Group. Lancet. 1995;345:1321-1325.
    • (1995) Lancet , vol.345 , pp. 1321-1325
  • 5
    • 0032526253 scopus 로고    scopus 로고
    • A blinded, long-term randomized multicenter study of mycophenolate mofetil in cadaveric renal transplantation: Results at three years
    • Tricontinental Mycophenolate Mofetil Renal Transplantation Study Group
    • Mathew TH. A blinded, long-term randomized multicenter study of mycophenolate mofetil in cadaveric renal transplantation: results at three years. Tricontinental Mycophenolate Mofetil Renal Transplantation Study Group. Transplantation. 1998;65:1450-1454.
    • (1998) Transplantation , vol.65 , pp. 1450-1454
    • Mathew, T.H.1
  • 6
    • 0029115531 scopus 로고
    • Mycophenolate mofetil for the prevention of acute rejection in primary cadaveric renal allograft recipients
    • U.S. Renal Transplant Mycophenolate Mofetil Study Group
    • Sollinger HW. Mycophenolate mofetil for the prevention of acute rejection in primary cadaveric renal allograft recipients. U.S. Renal Transplant Mycophenolate Mofetil Study Group. Transplantation. 1995;60:225-232.
    • (1995) Transplantation , vol.60 , pp. 225-232
    • Sollinger, H.W.1
  • 7
    • 0006986048 scopus 로고    scopus 로고
    • A blinded, randomized clinical trial of mycophenolate mofetil for the prevention of acute rejection in cadaveric renal transplantation
    • The Tricontinental Mycophenolate Mofetil Renal Transplantation Study Group
    • Tricontinental Mycophenolate Mofetil Renal Transplantation Study Group. A blinded, randomized clinical trial of mycophenolate mofetil for the prevention of acute rejection in cadaveric renal transplantation. The Tricontinental Mycophenolate Mofetil Renal Transplantation Study Group. Transplantation. 1996;61:1029-1037.
    • (1996) Transplantation , vol.61 , pp. 1029-1037
  • 8
    • 0035000726 scopus 로고    scopus 로고
    • A randomized double-blind comparative study of mycophenolate mofetil and azathioprine in combination with cyclosporine and corticosteroids in primary liver transplant recipients
    • Wiesner R, Rabkin J, Klintmalm G, et al. A randomized double-blind comparative study of mycophenolate mofetil and azathioprine in combination with cyclosporine and corticosteroids in primary liver transplant recipients. Liver Transplant. 2001;7:442-450.
    • (2001) Liver Transplant , vol.7 , pp. 442-450
    • Wiesner, R.1    Rabkin, J.2    Klintmalm, G.3
  • 9
    • 20244388105 scopus 로고    scopus 로고
    • A randomized active-controlled trial of mycophenolate mofetil in heart transplant recipients
    • Mycophenolate Mofetil Investigators
    • Kobashigawa J, Miller L, Renlund D, et al. A randomized active-controlled trial of mycophenolate mofetil in heart transplant recipients. Mycophenolate Mofetil Investigators. Transplantation. 1998;66:507-515.
    • (1998) Transplantation , vol.66 , pp. 507-515
    • Kobashigawa, J.1    Miller, L.2    Renlund, D.3
  • 10
    • 21044458269 scopus 로고    scopus 로고
    • Three-year results of a randomized, double-blind, controlled trial of mycophenolate mofetil versus azathioprine in cardiac transplant recipients
    • Eisen HJ, Kobashigawa J, Keogh A, et al. Three-year results of a randomized, double-blind, controlled trial of mycophenolate mofetil versus azathioprine in cardiac transplant recipients. J Heart Lung Transplant. 2005;24:517-525.
    • (2005) J Heart Lung Transplant , vol.24 , pp. 517-525
    • Eisen, H.J.1    Kobashigawa, J.2    Keogh, A.3
  • 11
    • 0035960579 scopus 로고    scopus 로고
    • Mycophenolate mofetil versus azathioprine in patients surviving the initial cardiac transplant hospitalization: An analysis of the Joint UNOS/ISHLT Thoracic Registry
    • Hosenpud JD, Bennett LE. Mycophenolate mofetil versus azathioprine in patients surviving the initial cardiac transplant hospitalization: an analysis of the Joint UNOS/ISHLT Thoracic Registry. Transplantation. 2001;72:1662-1665.
    • (2001) Transplantation , vol.72 , pp. 1662-1665
    • Hosenpud, J.D.1    Bennett, L.E.2
  • 12
    • 14644437155 scopus 로고    scopus 로고
    • Differential effects of donor age in liver transplant recipients infected with hepatitis B, hepatitis C and without viral hepatitis
    • Lake JR, Shorr JS, Steffen BJ, et al. Differential effects of donor age in liver transplant recipients infected with hepatitis B, hepatitis C and without viral hepatitis. Am J Transplant. 2005;5:549-557.
    • (2005) Am J Transplant , vol.5 , pp. 549-557
    • Lake, J.R.1    Shorr, J.S.2    Steffen, B.J.3
  • 13
    • 0034660104 scopus 로고    scopus 로고
    • Mycophenolate mofetil reduces late renal allograft loss independent of acute rejection
    • Ojo AO, Meier-Kriesche HU, Hanson JA, et al. Mycophenolate mofetil reduces late renal allograft loss independent of acute rejection. Transplantation. 2000;69:2405-2409.
    • (2000) Transplantation , vol.69 , pp. 2405-2409
    • Ojo, A.O.1    Meier-Kriesche, H.U.2    Hanson, J.A.3
  • 14
    • 13044305870 scopus 로고    scopus 로고
    • The pharmacokinetic-pharmacodynamic relationship for mycophenolate mofetil in renal transplantation
    • Hale MD, Nicholls AJ, Bullingham RE, et al. The pharmacokinetic- pharmacodynamic relationship for mycophenolate mofetil in renal transplantation. Clin Pharmacol Ther. 1998;64:672-683.
    • (1998) Clin Pharmacol Ther , vol.64 , pp. 672-683
    • Hale, M.D.1    Nicholls, A.J.2    Bullingham, R.E.3
  • 15
    • 0033767894 scopus 로고    scopus 로고
    • Mycophenolic acid concentrations are associated with cardiac allograft rejection
    • DeNofrio D, Loh E, Kao A, et al. Mycophenolic acid concentrations are associated with cardiac allograft rejection. J Heart Lung Transplant. 2000;19:1071-1076.
    • (2000) J Heart Lung Transplant , vol.19 , pp. 1071-1076
    • DeNofrio, D.1    Loh, E.2    Kao, A.3
  • 16
    • 0032985090 scopus 로고    scopus 로고
    • The efficacy of the combination of tacrolimus and mycophenolate mofetil for prevention of acute myocardial rejection is dependent on routine monitoring of mycophenolic acid trough acid levels
    • Meiser BM, Pfeiffer M, Schmidt D, et al. The efficacy of the combination of tacrolimus and mycophenolate mofetil for prevention of acute myocardial rejection is dependent on routine monitoring of mycophenolic acid trough acid levels. Transplant Proc. 1999;31:84-87.
    • (1999) Transplant Proc , vol.31 , pp. 84-87
    • Meiser, B.M.1    Pfeiffer, M.2    Schmidt, D.3
  • 17
    • 0034660341 scopus 로고    scopus 로고
    • The impact of routine mycophenolate mofetil drug monitoring on the treatment of cardiac allograft rejection
    • Yamani MH, Starling RC, Goormastic M, et al. The impact of routine mycophenolate mofetil drug monitoring on the treatment of cardiac allograft rejection. Transplantation. 2000;69:2326-2330.
    • (2000) Transplantation , vol.69 , pp. 2326-2330
    • Yamani, M.H.1    Starling, R.C.2    Goormastic, M.3
  • 18
    • 3142570574 scopus 로고    scopus 로고
    • Age-dependency of mycophenolate mofetil dosing in combination with tacrolimus after pediatric renal transplantation
    • Filler G, Foster J, Berard R, et al. Age-dependency of mycophenolate mofetil dosing in combination with tacrolimus after pediatric renal transplantation. Transplant Proc. 2004;36:1327-1331.
    • (2004) Transplant Proc , vol.36 , pp. 1327-1331
    • Filler, G.1    Foster, J.2    Berard, R.3
  • 19
    • 0033609476 scopus 로고    scopus 로고
    • A randomized double-blind, multicenter plasma concentration controlled study of the safety and efficacy of oral mycophenolate mofetil for the prevention of acute rejection after kidney transplantation
    • van Gelder T, Hilbrands LB, Vanrenterghem Y, et al. A randomized double-blind, multicenter plasma concentration controlled study of the safety and efficacy of oral mycophenolate mofetil for the prevention of acute rejection after kidney transplantation. Transplantation. 1999;68:261-266.
    • (1999) Transplantation , vol.68 , pp. 261-266
    • Van Gelder, T.1    Hilbrands, L.B.2    Vanrenterghem, Y.3
  • 20
    • 12944260647 scopus 로고    scopus 로고
    • Pharmacokinetic and metabolic investigations of mycophenolic acid in pediatric patients after renal transplantation: Implications for therapeutic drug monitoring
    • German Study Group on Mycophenolate Mofetil Therapy in Pediatric Renal Transplant Recipients
    • Oellerich M, Shipkova M, Schutz E, et al. Pharmacokinetic and metabolic investigations of mycophenolic acid in pediatric patients after renal transplantation: implications for therapeutic drug monitoring. German Study Group on Mycophenolate Mofetil Therapy in Pediatric Renal Transplant Recipients. Ther Drug Monit. 2000;22:20-26.
    • (2000) Ther Drug Monit , vol.22 , pp. 20-26
    • Oellerich, M.1    Shipkova, M.2    Schutz, E.3
  • 21
    • 0036191888 scopus 로고    scopus 로고
    • The pharmacokinetic-pharmacodynamic relationship for total and free mycophenolic Acid in pediatric renal transplant recipients: A report of the German Study Group on Mycophenolate Mofetil Therapy
    • Weber LT, Shipkova M, Armstrong VW, et al. The pharmacokinetic- pharmacodynamic relationship for total and free mycophenolic Acid in pediatric renal transplant recipients: a report of the German Study Group on Mycophenolate Mofetil Therapy. J Am Soc Nephrol. 2002;13:759-768.
    • (2002) J Am Soc Nephrol , vol.13 , pp. 759-768
    • Weber, L.T.1    Shipkova, M.2    Armstrong, V.W.3
  • 22
    • 3042743984 scopus 로고    scopus 로고
    • Early adequate mycophenolic acid exposure is associated with less rejection in kidney transplantation
    • Kiberd BA, Lawen J, Fraser AD, et al. Early adequate mycophenolic acid exposure is associated with less rejection in kidney transplantation. Am J Transplant. 2004;4:1079-1083.
    • (2004) Am J Transplant , vol.4 , pp. 1079-1083
    • Kiberd, B.A.1    Lawen, J.2    Fraser, A.D.3
  • 23
    • 17644377916 scopus 로고    scopus 로고
    • Cyclosporine interacts with mycophenolic acid by inhibiting the multidrug resistance-associated protein 2
    • Hesselink DA, van Hest RM, Mathot RA, et al. Cyclosporine interacts with mycophenolic acid by inhibiting the multidrug resistance-associated protein 2. Am J Transplant. 2005;5:987-994.
    • (2005) Am J Transplant , vol.5 , pp. 987-994
    • Hesselink, D.A.1    Van Hest, R.M.2    Mathot, R.A.3
  • 24
    • 0035086852 scopus 로고    scopus 로고
    • Comparison of the effects of tacrolimus and cyclosporine on the pharmacokinetics of mycophenolic acid
    • van Gelder T, Klupp J, Barten MJ, et al. Comparison of the effects of tacrolimus and cyclosporine on the pharmacokinetics of mycophenolic acid. Ther Drug Monit. 2001;23:119-128.
    • (2001) Ther Drug Monit , vol.23 , pp. 119-128
    • Van Gelder, T.1    Klupp, J.2    Barten, M.J.3
  • 25
    • 27744527131 scopus 로고    scopus 로고
    • Cyclosporine withdrawal from a mycophenolate mofetil-containing immunosuppressive regimen: Results of a five-year, prospective, randomized study
    • Abramowicz D, Del Carmen Rial M, Vitko S, et al. Cyclosporine withdrawal from a mycophenolate mofetil-containing immunosuppressive regimen: results of a five-year, prospective, randomized study. J Am Soc Nephrol. 2005;16:2234-2240.
    • (2005) J Am Soc Nephrol , vol.16 , pp. 2234-2240
    • Abramowicz, D.1    Del Carmen Rial, M.2    Vitko, S.3
  • 26
    • 33645453843 scopus 로고    scopus 로고
    • The use of daclizumab and MMF in combination with corticosteroids and cyclosporine (low dose versus low dose followed by withdrawal) to optimize renal function in recipients of renal allografts
    • abstract and poster. Abstract P734
    • Ekberg H, Grinyo JM, Nashan B, et al. The use of daclizumab and MMF in combination with corticosteroids and cyclosporine (low dose versus low dose followed by withdrawal) to optimize renal function in recipients of renal allografts. [abstract and poster]. Transplantation. 2004;78:458-459. [Abstract P734]
    • (2004) Transplantation , vol.78 , pp. 458-459
    • Ekberg, H.1    Grinyo, J.M.2    Nashan, B.3
  • 27
    • 4344645217 scopus 로고    scopus 로고
    • Lack of correlation between mycophenolate mofetil dose and MPA level in pediatric and young adult cardiac transplant patients: Does the MPA level matter?
    • Gajarski RJ, Crowley DC, Zamberlan MC, et al. Lack of correlation between mycophenolate mofetil dose and MPA level in pediatric and young adult cardiac transplant patients: does the MPA level matter? Am J Transplant. 2004;4:1495-1500.
    • (2004) Am J Transplant , vol.4 , pp. 1495-1500
    • Gajarski, R.J.1    Crowley, D.C.2    Zamberlan, M.C.3
  • 28
    • 0032947542 scopus 로고    scopus 로고
    • Combination therapy with tacrolimus and mycophenolate mofetil following cardiac transplantation: Importance of mycophenolic acid therapeutic drug monitoring
    • Meiser BM, Pfeiffer M, Schmidt D, et al. Combination therapy with tacrolimus and mycophenolate mofetil following cardiac transplantation: importance of mycophenolic acid therapeutic drug monitoring. J Heart Lung Transplant. 1999;18:143-149.
    • (1999) J Heart Lung Transplant , vol.18 , pp. 143-149
    • Meiser, B.M.1    Pfeiffer, M.2    Schmidt, D.3
  • 29
    • 4143150741 scopus 로고    scopus 로고
    • Tacrolimus or cyclosporine: Which is the better partner for mycophenolate mofetil in heart transplant recipients?
    • Meiser BM, Groetzner J, Kaczmarek I, et al. Tacrolimus or cyclosporine: which is the better partner for mycophenolate mofetil in heart transplant recipients? Transplantation. 2004;78:591-598.
    • (2004) Transplantation , vol.78 , pp. 591-598
    • Meiser, B.M.1    Groetzner, J.2    Kaczmarek, I.3
  • 30
    • 2042515610 scopus 로고    scopus 로고
    • Clinical efficacy and toxicity profile of tacrolimus and mycophenolic acid in relation to combined long-term pharmacokinetics in de novo renal allograft recipients
    • Kuypers DR, Claes K, Evenepoel P, et al. Clinical efficacy and toxicity profile of tacrolimus and mycophenolic acid in relation to combined long-term pharmacokinetics in de novo renal allograft recipients. Clin Pharmacol Ther. 2004;75:434-447.
    • (2004) Clin Pharmacol Ther , vol.75 , pp. 434-447
    • Kuypers, D.R.1    Claes, K.2    Evenepoel, P.3
  • 31
    • 0035119174 scopus 로고    scopus 로고
    • A retrospective analysis of mycophenolic acid and cyclosporin concentrations with acute rejection in renal transplant recipients
    • Pillans PI, Rigby RJ, Kubler P, et al. A retrospective analysis of mycophenolic acid and cyclosporin concentrations with acute rejection in renal transplant recipients. Clin Biochem. 2001;34:77-81.
    • (2001) Clin Biochem , vol.34 , pp. 77-81
    • Pillans, P.I.1    Rigby, R.J.2    Kubler, P.3
  • 32
    • 0038246498 scopus 로고    scopus 로고
    • Mycophenolic acid pharmacodynamics and pharmacokinetics provide a basis for rational monitoring strategies
    • Shaw LM, Korecka M, Venkataramanan R, et al. Mycophenolic acid pharmacodynamics and pharmacokinetics provide a basis for rational monitoring strategies. Am J Transplant. 2003;3:534-542.
    • (2003) Am J Transplant , vol.3 , pp. 534-542
    • Shaw, L.M.1    Korecka, M.2    Venkataramanan, R.3
  • 33
    • 16644381286 scopus 로고    scopus 로고
    • Intraindividual and interindividual variations in the pharmacokinetics of mycophenolic acid in liver transplant patients
    • Pisupati J, Jain A, Burckart G, et al. Intraindividual and interindividual variations in the pharmacokinetics of mycophenolic acid in liver transplant patients. J Clin Pharmacol. 2005;45:34-41.
    • (2005) J Clin Pharmacol , vol.45 , pp. 34-41
    • Pisupati, J.1    Jain, A.2    Burckart, G.3
  • 34
    • 1842477100 scopus 로고    scopus 로고
    • Monitoring mycophenolate in liver transplant recipients: Toward a therapeutic range
    • Tredger JM, Brown NW, Adams J, et al. Monitoring mycophenolate in liver transplant recipients: toward a therapeutic range. Liver Transpl. 2004;10:492-502.
    • (2004) Liver Transpl , vol.10 , pp. 492-502
    • Tredger, J.M.1    Brown, N.W.2    Adams, J.3
  • 35
    • 0035123682 scopus 로고    scopus 로고
    • Pharmacokinetics of mycophenolic acid after mycophenolate mofetil administration in liver transplant patients treated with tacrolimus
    • Jain A, Venkataramanan R, Hamad IS, et al. Pharmacokinetics of mycophenolic acid after mycophenolate mofetil administration in liver transplant patients treated with tacrolimus. J Clin Pharmacol. 2001;41:268-276.
    • (2001) J Clin Pharmacol , vol.41 , pp. 268-276
    • Jain, A.1    Venkataramanan, R.2    Hamad, I.S.3
  • 36
    • 19544364671 scopus 로고    scopus 로고
    • Best single time points as surrogates to the tacrolimus and mycophenolic acid area under the curve in adult liver transplant patients beyond 12 months of transplantation
    • Mardigyan V, Tchervenkov J, Metrakos P, et al. Best single time points as surrogates to the tacrolimus and mycophenolic acid area under the curve in adult liver transplant patients beyond 12 months of transplantation. Clin Ther. 2005;27:463-469.
    • (2005) Clin Ther , vol.27 , pp. 463-469
    • Mardigyan, V.1    Tchervenkov, J.2    Metrakos, P.3
  • 37
    • 21844464292 scopus 로고    scopus 로고
    • Therapeutic mycophenolic acid monitoring by means of limited sampling strategy in orthotopic heart transplant patients
    • Baraldo M, Isola M, Feruglio MT, et al. Therapeutic mycophenolic acid monitoring by means of limited sampling strategy in orthotopic heart transplant patients. Transplant Proc. 2005;37:2240-2243.
    • (2005) Transplant Proc , vol.37 , pp. 2240-2243
    • Baraldo, M.1    Isola, M.2    Feruglio, M.T.3
  • 38
    • 0034961129 scopus 로고    scopus 로고
    • Pharmacokinetic basis for the efficient and safe use of low-dose mycophenolate mofetil in combination with tacrolimus in kidney transplantation
    • Mourad M, Malaise J, Chaib Eddour D, et al. Pharmacokinetic basis for the efficient and safe use of low-dose mycophenolate mofetil in combination with tacrolimus in kidney transplantation. Clin Chem. 2001;47:1241-1248.
    • (2001) Clin Chem , vol.47 , pp. 1241-1248
    • Mourad, M.1    Malaise, J.2    Chaib Eddour, D.3
  • 39
    • 0036299291 scopus 로고    scopus 로고
    • Therapeutic monitoring of mycophenolate mofetil in organ transplant recipients: Is it necessary?
    • Mourad M, Wallemacq P, Konig J, et al. Therapeutic monitoring of mycophenolate mofetil in organ transplant recipients: is it necessary? Clin Pharmacokinet. 2002;41:319-327.
    • (2002) Clin Pharmacokinet , vol.41 , pp. 319-327
    • Mourad, M.1    Wallemacq, P.2    Konig, J.3
  • 40
    • 0034102949 scopus 로고    scopus 로고
    • Determination of the acyl glucuronide metabolite of mycophenolic acid in human plasma by HPLC and EMIT
    • Shipkova M, Schütz E, Armstrong VW, et al. Determination of the acyl glucuronide metabolite of mycophenolic acid in human plasma by HPLC and EMIT. Clin Chem. 2000;46:365-372.
    • (2000) Clin Chem , vol.46 , pp. 365-372
    • Shipkova, M.1    Schütz, E.2    Armstrong, V.W.3
  • 41
    • 0037306174 scopus 로고    scopus 로고
    • Acyl glucuronide drug metabolites: Toxicological and analytical implications
    • Shipkova M, Armstrong VW, Oellerich M, et al. Acyl glucuronide drug metabolites: toxicological and analytical implications. Ther Drug Monit. 2003;25:1-16.
    • (2003) Ther Drug Monit , vol.25 , pp. 1-16
    • Shipkova, M.1    Armstrong, V.W.2    Oellerich, M.3
  • 42
    • 0036785072 scopus 로고    scopus 로고
    • Mycophenolic acid and mycophenolic acid glucuronide pharmacokinetics in pediatric liver transplant recipients: Effect of cyclosporine and tacrolimus comedication
    • Brown NW, Aw MM, Mieli-Vergani G, et al. Mycophenolic acid and mycophenolic acid glucuronide pharmacokinetics in pediatric liver transplant recipients: effect of cyclosporine and tacrolimus comedication. Ther Drug Monit. 2002;24:598-606.
    • (2002) Ther Drug Monit , vol.24 , pp. 598-606
    • Brown, N.W.1    Aw, M.M.2    Mieli-Vergani, G.3
  • 43
    • 0003027160 scopus 로고    scopus 로고
    • Pharmacokinetics and pharmacodynamics of mycophenolic acid in stable renal transplant recipients treated with low doses of mycophenolate mofetil
    • Brunet M, Martorell J, Oppenheimer F, et al. Pharmacokinetics and pharmacodynamics of mycophenolic acid in stable renal transplant recipients treated with low doses of mycophenolate mofetil. Transplant Int. 2000;13(Suppl 1):S301-S305.
    • (2000) Transplant Int , vol.13 , Issue.1 SUPPL.
    • Brunet, M.1    Martorell, J.2    Oppenheimer, F.3
  • 44
    • 0034042130 scopus 로고    scopus 로고
    • Limited sampling strategy for mycophenolic acid area under the curve
    • Filler G, Mai I. Limited sampling strategy for mycophenolic acid area under the curve. Ther Drug Monit. 2000;22:169-173.
    • (2000) Ther Drug Monit , vol.22 , pp. 169-173
    • Filler, G.1    Mai, I.2
  • 45
    • 0032720414 scopus 로고    scopus 로고
    • The kinetics of mycophenolic acid and its glucuronide metabolite in adult kidney transplant recipients
    • Johnson AG, Rigby RJ, Taylor PJ, et al. The kinetics of mycophenolic acid and its glucuronide metabolite in adult kidney transplant recipients. Clin Pharmacol Ther. 1999;66:492-500.
    • (1999) Clin Pharmacol Ther , vol.66 , pp. 492-500
    • Johnson, A.G.1    Rigby, R.J.2    Taylor, P.J.3
  • 46
    • 0035712708 scopus 로고    scopus 로고
    • Simultaneous estimation of cyclosporin and mycophenolic acid areas under the curve in stable renal transplant patients using a limited sampling strategy
    • Le Guellec C, Buchler M, Giraudeau B, et al. Simultaneous estimation of cyclosporin and mycophenolic acid areas under the curve in stable renal transplant patients using a limited sampling strategy. Eur J Clin Pharmacol. 2002;57:805-811.
    • (2002) Eur J Clin Pharmacol , vol.57 , pp. 805-811
    • Le Guellec, C.1    Buchler, M.2    Giraudeau, B.3
  • 47
    • 0036721306 scopus 로고    scopus 로고
    • Limited sampling strategy for the estimation of mycophenolic acid area under the curve in adult renal transplant patients treated with concomitant tacrolimus
    • Pawinski T, Hale M, Korecka M, et al. Limited sampling strategy for the estimation of mycophenolic acid area under the curve in adult renal transplant patients treated with concomitant tacrolimus. Clin Chem. 2002;48:1497-1504.
    • (2002) Clin Chem , vol.48 , pp. 1497-1504
    • Pawinski, T.1    Hale, M.2    Korecka, M.3
  • 48
    • 13144251149 scopus 로고    scopus 로고
    • Limited sampling strategy for the determination of mycophenolic acid area under the curve in pediatric kidney recipients
    • German Study Group on Mycophenolate Mofetil Therapy in Pediatric Renal Transplant Recipients
    • Schutz E, Armstrong VW, Shipkova M, et al. Limited sampling strategy for the determination of mycophenolic acid area under the curve in pediatric kidney recipients. German Study Group on Mycophenolate Mofetil Therapy in Pediatric Renal Transplant Recipients. Transplant Proc. 1998;30:1182-1184.
    • (1998) Transplant Proc , vol.30 , pp. 1182-1184
    • Schutz, E.1    Armstrong, V.W.2    Shipkova, M.3
  • 49
    • 0035116884 scopus 로고    scopus 로고
    • Pharmacokinetic, pharmacodynamic, and outcome investigations as the basis for mycophenolic acid therapeutic drug monitoring in renal and heart transplant patients
    • Shaw LM, Korecka M, DeNofrio D, et al. Pharmacokinetic, pharmacodynamic, and outcome investigations as the basis for mycophenolic acid therapeutic drug monitoring in renal and heart transplant patients. Clin Biochem. 2001;34:17-22.
    • (2001) Clin Biochem , vol.34 , pp. 17-22
    • Shaw, L.M.1    Korecka, M.2    DeNofrio, D.3
  • 50
    • 0031926842 scopus 로고    scopus 로고
    • Pharmacokinetics of mycophenolic acid (MPA) and determinants of MPA free fraction in pediatric and adult renal transplant recipients
    • German Study group on Mycophenolate Mofetil Therapy in Pediatric Renal Transplant Recipients
    • Weber LT, Shipkova M, Lamersdorf T, et al. Pharmacokinetics of mycophenolic acid (MPA) and determinants of MPA free fraction in pediatric and adult renal transplant recipients. German Study group on Mycophenolate Mofetil Therapy in Pediatric Renal Transplant Recipients. J Am Soc Nephrol. 1998;9:1511-1520.
    • (1998) J Am Soc Nephrol , vol.9 , pp. 1511-1520
    • Weber, L.T.1    Shipkova, M.2    Lamersdorf, T.3
  • 51
    • 0036177714 scopus 로고    scopus 로고
    • Comparison of the EMIT immunoassay with HPLC for therapeutic drug monitoring of mycophenolic acid in pediatric renal-transplant recipients on mycophenolate mofetil therapy
    • Weber LT, Shipkova M, Armstrong VW, et al. Comparison of the EMIT immunoassay with HPLC for therapeutic drug monitoring of mycophenolic acid in pediatric renal-transplant recipients on mycophenolate mofetil therapy. Clin Chem. 2002;48:517-525.
    • (2002) Clin Chem , vol.48 , pp. 517-525
    • Weber, L.T.1    Shipkova, M.2    Armstrong, V.W.3
  • 52
    • 0035148545 scopus 로고    scopus 로고
    • Correlation of mycophenolic acid pharmacokinetic parameters with side effects in kidney transplant patients treated with mycophenolate mofetil
    • Mourad M, Malaise J, Chaib Eddour D, et al. Correlation of mycophenolic acid pharmacokinetic parameters with side effects in kidney transplant patients treated with mycophenolate mofetil. Clin Chem. 2001;47:88-94.
    • (2001) Clin Chem , vol.47 , pp. 88-94
    • Mourad, M.1    Malaise, J.2    Chaib Eddour, D.3
  • 53
    • 0038298273 scopus 로고    scopus 로고
    • Long-term changes in mycophenolic acid exposure in combination with tacrolimus and corticosteroids are dose dependent and not reflected by trough plasma concentration: A prospective study in 100 de novo renal allograft recipients
    • Kuypers DR, Claes K, Evenepoel P, et al. Long-term changes in mycophenolic acid exposure in combination with tacrolimus and corticosteroids are dose dependent and not reflected by trough plasma concentration: a prospective study in 100 de novo renal allograft recipients. J Clin Pharmacol. 2003;43:866-880.
    • (2003) J Clin Pharmacol , vol.43 , pp. 866-880
    • Kuypers, D.R.1    Claes, K.2    Evenepoel, P.3
  • 54
    • 2442712496 scopus 로고    scopus 로고
    • Abbreviated mycophenolic acid AUC from C0, C1, C2, and C4 is preferable in children after renal transplantation on mycophenolate mofetil and tacrolimus therapy
    • Filler G. Abbreviated mycophenolic acid AUC from C0, C1, C2, and C4 is preferable in children after renal transplantation on mycophenolate mofetil and tacrolimus therapy. Transplant Int. 2004;17:120-125.
    • (2004) Transplant Int , vol.17 , pp. 120-125
    • Filler, G.1
  • 55
    • 0032812557 scopus 로고    scopus 로고
    • Therapeutic drug monitoring of total and free mycophenolic acid (MPA) and limited sampling strategy for determination of MPA-AUC in paediatric renal transplant recipients
    • The German Study Group on Mycophenolate Mofetil (mycophenolate mofetil) Therapy
    • Weber LT, Schutz E, Lamersdorf T, et al. Therapeutic drug monitoring of total and free mycophenolic acid (MPA) and limited sampling strategy for determination of MPA-AUC in paediatric renal transplant recipients. The German Study Group on Mycophenolate Mofetil (mycophenolate mofetil) Therapy. Nephrol Dial Transplant. 1999;14(Suppl 4):34-35.
    • (1999) Nephrol Dial Transplant , vol.14 , Issue.4 SUPPL. , pp. 34-35
    • Weber, L.T.1    Schutz, E.2    Lamersdorf, T.3
  • 56
    • 0035085913 scopus 로고    scopus 로고
    • Determination of mycophenolate area under the curve by limited sampling strategy
    • Yeung S, Tong KL, Tsang WK, et al. Determination of mycophenolate area under the curve by limited sampling strategy. Transplant Proc. 2001;33:1052-1053.
    • (2001) Transplant Proc , vol.33 , pp. 1052-1053
    • Yeung, S.1    Tong, K.L.2    Tsang, W.K.3
  • 57
    • 33748141347 scopus 로고    scopus 로고
    • Limited sampling strategy for the estimation of mycophenolic acid: A large scale study
    • Premaud A, Le Meur Y, Rousseau A, et al. Limited sampling strategy for the estimation of mycophenolic acid: a large scale study. Ther Drug Monit. 2003;25:504.
    • (2003) Ther Drug Monit , vol.25 , pp. 504
    • Premaud, A.1    Le Meur, Y.2    Rousseau, A.3
  • 58
    • 15844416494 scopus 로고    scopus 로고
    • Enteric-coated mycophenolate sodium delivers bioequivalent MPA exposure compared with mycophenolate mofetil
    • Arns W, Breuer S, Choudhury S, et al. Enteric-coated mycophenolate sodium delivers bioequivalent MPA exposure compared with mycophenolate mofetil. Clin Transplant. 2005;19:199-206.
    • (2005) Clin Transplant , vol.19 , pp. 199-206
    • Arns, W.1    Breuer, S.2    Choudhury, S.3
  • 59
    • 23744457170 scopus 로고    scopus 로고
    • A double absorption-phase model adequately describes mycophenolic acid plasma profiles in de novo renal transplant recipients given oral mycophenolate mofetil
    • Premaud A, Debord J, Rousseau A, et al. A double absorption-phase model adequately describes mycophenolic acid plasma profiles in de novo renal transplant recipients given oral mycophenolate mofetil. Clin Pharmacokinet. 2005;44:837-847.
    • (2005) Clin Pharmacokinet , vol.44 , pp. 837-847
    • Premaud, A.1    Debord, J.2    Rousseau, A.3
  • 60
    • 20044394189 scopus 로고    scopus 로고
    • Maximum a posteriori Bayesian estimation of mycophenolic acid pharmacokinetics in renal transplant recipients at different postgrafting periods
    • Premaud A, Le Meur Y, Debord J, et al. Maximum a posteriori Bayesian estimation of mycophenolic acid pharmacokinetics in renal transplant recipients at different postgrafting periods. Ther Drug Monit. 2005;27:354-361.
    • (2005) Ther Drug Monit , vol.27 , pp. 354-361
    • Premaud, A.1    Le Meur, Y.2    Debord, J.3
  • 61
    • 33748183473 scopus 로고    scopus 로고
    • Concentration-controlled versus fixed dose of MMF in kidney transplant recipients: Preliminary results of a French Multicenter Randomized Study
    • Seattle, WA
    • LeMeur Y, Büchler M, Lavaud S, et al. Concentration-controlled versus fixed dose of MMF in kidney transplant recipients: preliminary results of a French Multicenter Randomized Study [abstract]. In: American Congress of Transplantation. Seattle, WA; 2005.
    • (2005) American Congress of Transplantation
    • LeMeur, Y.1    Büchler, M.2    Lavaud, S.3
  • 62
    • 0344412976 scopus 로고    scopus 로고
    • Mycophenolate pharmacokinetics in early period following lung or heart transplantation
    • Ensom MH, Partovi N, Decarie D, et al. Mycophenolate pharmacokinetics in early period following lung or heart transplantation. Ann Pharmacother. 2003;37:1761-1767.
    • (2003) Ann Pharmacother , vol.37 , pp. 1761-1767
    • Ensom, M.H.1    Partovi, N.2    Decarie, D.3
  • 63
    • 16244370110 scopus 로고    scopus 로고
    • Predicting the usefulness of therapeutic drug monitoring of mycophenolic acid: A computer simulation
    • van Hest R, Mathot R, Vulto A, et al. Predicting the usefulness of therapeutic drug monitoring of mycophenolic acid: a computer simulation. Ther Drug Monit. 2005;27:163-167.
    • (2005) Ther Drug Monit , vol.27 , pp. 163-167
    • Van Hest, R.1    Mathot, R.2    Vulto, A.3
  • 64
    • 21844466718 scopus 로고    scopus 로고
    • Impact of mycophenolate mofetil loading on drug exposure in the early post transplant period
    • Kiberd BA, Puthenparumpil JJ, Fraser A, et al. Impact of mycophenolate mofetil loading on drug exposure in the early post transplant period. Transplant Proc. 2005;37:2320-2323.
    • (2005) Transplant Proc , vol.37 , pp. 2320-2323
    • Kiberd, B.A.1    Puthenparumpil, J.J.2    Fraser, A.3
  • 65
    • 20044361837 scopus 로고    scopus 로고
    • Pharmacokinetics and bioavailability of mycophenolic acid after intravenous administration and oral administration of mycophenolate mofetil to heart transplant recipients
    • Armstrong VW, Tenderich G, Shipkova M, et al. Pharmacokinetics and bioavailability of mycophenolic acid after intravenous administration and oral administration of mycophenolate mofetil to heart transplant recipients. Ther Drug Monit. 2005;27:315-321.
    • (2005) Ther Drug Monit , vol.27 , pp. 315-321
    • Armstrong, V.W.1    Tenderich, G.2    Shipkova, M.3
  • 66
    • 0035085701 scopus 로고    scopus 로고
    • Monitoring of mycophenolic acid in pediatric renal transplant recipients
    • Armstrong VW, Shipkova M, Schutz E, et al. Monitoring of mycophenolic acid in pediatric renal transplant recipients. Transplant Proc. 2001;33:1040-1043.
    • (2001) Transplant Proc , vol.33 , pp. 1040-1043
    • Armstrong, V.W.1    Shipkova, M.2    Schutz, E.3
  • 67
    • 9644258582 scopus 로고    scopus 로고
    • Comparison of liquid chromatography-tandem mass spectrometry with a commercial enzyme-multiplied immunoassay for the determination of plasma MPA in renal transplant recipients and consequences for therapeutic drug monitoring
    • Premaud A, Rousseau A, Le Meur Y, et al. Comparison of liquid chromatography-tandem mass spectrometry with a commercial enzyme-multiplied immunoassay for the determination of plasma MPA in renal transplant recipients and consequences for therapeutic drug monitoring. Ther Drug Monit. 2004;26:609-619.
    • (2004) Ther Drug Monit , vol.26 , pp. 609-619
    • Premaud, A.1    Rousseau, A.2    Le Meur, Y.3
  • 68
    • 2542590879 scopus 로고    scopus 로고
    • Free mycophenolic acid should be monitored in renal transplant recipients with hypoalbuminemia
    • Atcheson BA, Taylor PJ, Kirkpatrick CM, et al. Free mycophenolic acid should be monitored in renal transplant recipients with hypoalbuminemia. Ther Drug Monit. 2004;26:284-286.
    • (2004) Ther Drug Monit , vol.26 , pp. 284-286
    • Atcheson, B.A.1    Taylor, P.J.2    Kirkpatrick, C.M.3
  • 69
    • 15244342623 scopus 로고    scopus 로고
    • Mycophenolic acid pharmacokinetics and related outcomes early after renal transplant
    • Atcheson BA, Taylor PJ, Mudge DW, et al. Mycophenolic acid pharmacokinetics and related outcomes early after renal transplant. Br J Clin Pharmacol. 2005;59:271-280.
    • (2005) Br J Clin Pharmacol , vol.59 , pp. 271-280
    • Atcheson, B.A.1    Taylor, P.J.2    Mudge, D.W.3
  • 70
    • 33748131056 scopus 로고    scopus 로고
    • Assessment of total and free mycophenolic acid in transplant patient plasma by enzyme receptor assay
    • Dorn AR, Tsai J, Mountain L, et al. Assessment of total and free mycophenolic acid in transplant patient plasma by enzyme receptor assay [abstract]. Ther Drug Monit. 2005;27:216-217.
    • (2005) Ther Drug Monit , vol.27 , pp. 216-217
    • Dorn, A.R.1    Tsai, J.2    Mountain, L.3
  • 71
    • 33748193178 scopus 로고    scopus 로고
    • Measurement of total and free mycophenolic acid with new enzyme receptor methods on COBAS INTEGRA systems
    • Domke I, Engelmayer J, Langmann T, et al. Measurement of total and free mycophenolic acid with new enzyme receptor methods on COBAS INTEGRA systems. Clin Chem. 2005;51:C148.
    • (2005) Clin Chem , vol.51
    • Domke, I.1    Engelmayer, J.2    Langmann, T.3
  • 72
    • 1642451707 scopus 로고    scopus 로고
    • Validation of a rapid and sensitive liquid chromatography-tandem mass spectrometry method for free and total mycophenolic acid
    • Streit F, Shipkova M, Armstrong VW, et al. Validation of a rapid and sensitive liquid chromatography-tandem mass spectrometry method for free and total mycophenolic acid. Clin Chem. 2004;50:152-159.
    • (2004) Clin Chem , vol.50 , pp. 152-159
    • Streit, F.1    Shipkova, M.2    Armstrong, V.W.3
  • 73
    • 0034523153 scopus 로고    scopus 로고
    • Pharmacodynamic monitoring of mycophenolate mofetil
    • Budde K, Glander P, Bauer S, et al. Pharmacodynamic monitoring of mycophenolate mofetil. Clin Chem Lab Med. 2000;38:1213-1216.
    • (2000) Clin Chem Lab Med , vol.38 , pp. 1213-1216
    • Budde, K.1    Glander, P.2    Bauer, S.3
  • 74
    • 0032732954 scopus 로고    scopus 로고
    • Pharmacodynamics of immunosuppression by mycophenolic acid: Inhibition of both lymphocyte proliferation and activation correlates with pharmacokinetics
    • Gummert JF, Barten MJ, Sherwood SW, et al. Pharmacodynamics of immunosuppression by mycophenolic acid: inhibition of both lymphocyte proliferation and activation correlates with pharmacokinetics. J Pharmacol Exp Ther. 1999;291:1100-1112.
    • (1999) J Pharmacol Exp Ther , vol.291 , pp. 1100-1112
    • Gummert, J.F.1    Barten, M.J.2    Sherwood, S.W.3
  • 75
    • 0035993723 scopus 로고    scopus 로고
    • Pharmacodynamic monitoring of mycophenolate mofetil in stable renal allograft recipients
    • Budde K, Braun KP, Glander P, et al. Pharmacodynamic monitoring of mycophenolate mofetil in stable renal allograft recipients. Transplant Proc. 2002;34:1748-1750.
    • (2002) Transplant Proc , vol.34 , pp. 1748-1750
    • Budde, K.1    Braun, K.P.2    Glander, P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.