Hybrid structure-based virtual screening protocol for the identification of novel BACE1 inhibitors

Journal of Chemical Information and Modeling

Volumn 49, Issue 3, 2009, Pages 647-657

  Vijayan, R S K ^a   Prabu, M ^a   Mascarenhas, Nahren Manuel ^a   Ghoshal, Nanda ^a  

^a INDIAN INSTITUTE OF CHEMICAL BIOLOGY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING ENERGY; DIGITAL LIBRARIES; GOLD; LIGANDS; MOLECULES; NEURODEGENERATIVE DISEASES;

ALZHEIMER'S DISEASE; ASPARTIC PROTEASE; CONSENSUS SCORING; GENETIC OPTIMIZATION; INTERACTION PATTERN; LEAD IDENTIFICATION; SMALL MOLECULE INHIBITOR; VIRTUAL SCREENING;

DIAGNOSIS;

ASPARTIC PROTEINASE; BACE1 PROTEIN, HUMAN; ENZYME INHIBITOR; SECRETASE;

ALZHEIMER DISEASE; ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; DRUG ANTAGONISM; ENZYMOLOGY; HUMAN; ROC CURVE;

ALZHEIMER DISEASE; AMYLOID PRECURSOR PROTEIN SECRETASES; ASPARTIC ENDOPEPTIDASES; ENZYME INHIBITORS; HUMANS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; ROC CURVE;

EID: 65249135573     PISSN: 15499596     EISSN: 1549960X     Source Type: Journal    
DOI: 10.1021/ci800386v     Document Type: Article

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