-
1
-
-
18844431062
-
Pancreatic cancer: basic and clinical aspects
-
Schneider G., Siveke J.T., Eckel F., et al. Pancreatic cancer: basic and clinical aspects. Gastroenterology 128 (2005) 1606-1625
-
(2005)
Gastroenterology
, vol.128
, pp. 1606-1625
-
-
Schneider, G.1
Siveke, J.T.2
Eckel, F.3
-
2
-
-
65249125270
-
Inhibition of γ-secretase activity inhibits tumor progression in a mouse model of pancreatic ductal adenocarcinoma
-
Plentz R., Park J.S., Rhim A.D., et al. Inhibition of γ-secretase activity inhibits tumor progression in a mouse model of pancreatic ductal adenocarcinoma. Gastroenterology 136 (2009) 1741-1749
-
(2009)
Gastroenterology
, vol.136
, pp. 1741-1749
-
-
Plentz, R.1
Park, J.S.2
Rhim, A.D.3
-
3
-
-
33947214529
-
Notch signaling, gamma-secretase inhibitors, and cancer therapy
-
Shih Ie M., and Wang T.L. Notch signaling, gamma-secretase inhibitors, and cancer therapy. Cancer Res 67 (2007) 1879-1882
-
(2007)
Cancer Res
, vol.67
, pp. 1879-1882
-
-
Shih Ie, M.1
Wang, T.L.2
-
5
-
-
58549093915
-
Developmental biology of the pancreas: a comprehensive review
-
Gittes G.K. Developmental biology of the pancreas: a comprehensive review. Dev Biol 326 (2009) 4-35
-
(2009)
Dev Biol
, vol.326
, pp. 4-35
-
-
Gittes, G.K.1
-
6
-
-
65249128642
-
Notch signaling as gatekeeper of rat acinar-to-beta cell conversion in vitro
-
Baeyens L., Bonne S., Bos T., et al. Notch signaling as gatekeeper of rat acinar-to-beta cell conversion in vitro. Gastroenterology 136 (2009) 1750-1760
-
(2009)
Gastroenterology
, vol.136
, pp. 1750-1760
-
-
Baeyens, L.1
Bonne, S.2
Bos, T.3
-
7
-
-
9144266295
-
Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse
-
Hingorani S.R., Petricoin E.F., Maitra A., et al. Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse. Cancer Cell 4 (2003) 437-450
-
(2003)
Cancer Cell
, vol.4
, pp. 437-450
-
-
Hingorani, S.R.1
Petricoin, E.F.2
Maitra, A.3
-
8
-
-
0346455774
-
Activated Kras and Ink4a/Arf deficiency cooperate to produce metastatic pancreatic ductal adenocarcinoma
-
Aguirre A.J., Bardeesy N., Sinha M., et al. Activated Kras and Ink4a/Arf deficiency cooperate to produce metastatic pancreatic ductal adenocarcinoma. Genes Dev 17 (2003) 3112-3126
-
(2003)
Genes Dev
, vol.17
, pp. 3112-3126
-
-
Aguirre, A.J.1
Bardeesy, N.2
Sinha, M.3
-
9
-
-
33645824724
-
Both p16(Ink4a) and the p19(Arf)-p53 pathway constrain progression of pancreatic adenocarcinoma in the mouse
-
Bardeesy N., Aguirre A.J., Chu G.C., et al. Both p16(Ink4a) and the p19(Arf)-p53 pathway constrain progression of pancreatic adenocarcinoma in the mouse. Proc Natl Acad Sci U S A 103 (2006) 5947-5952
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 5947-5952
-
-
Bardeesy, N.1
Aguirre, A.J.2
Chu, G.C.3
-
10
-
-
19344362405
-
Trp53R172H and KrasG12D cooperate to promote chromosomal instability and widely metastatic pancreatic ductal adenocarcinoma in mice
-
Hingorani S.R., Wang L., Multani A.S., et al. Trp53R172H and KrasG12D cooperate to promote chromosomal instability and widely metastatic pancreatic ductal adenocarcinoma in mice. Cancer Cell 7 (2005) 469-483
-
(2005)
Cancer Cell
, vol.7
, pp. 469-483
-
-
Hingorani, S.R.1
Wang, L.2
Multani, A.S.3
-
11
-
-
10744223624
-
Notch mediates TGF alpha-induced changes in epithelial differentiation during pancreatic tumorigenesis
-
Miyamoto Y., Maitra A., Ghosh B., et al. Notch mediates TGF alpha-induced changes in epithelial differentiation during pancreatic tumorigenesis. Cancer Cell 3 (2003) 565-576
-
(2003)
Cancer Cell
, vol.3
, pp. 565-576
-
-
Miyamoto, Y.1
Maitra, A.2
Ghosh, B.3
-
12
-
-
33847083871
-
Apoptosis in T cell acute lymphoblastic leukemia cells after cell cycle arrest induced by pharmacological inhibition of notch signaling
-
Lewis H.D., Leveridge M., Strack P.R., et al. Apoptosis in T cell acute lymphoblastic leukemia cells after cell cycle arrest induced by pharmacological inhibition of notch signaling. Chem Biol 14 (2007) 209-219
-
(2007)
Chem Biol
, vol.14
, pp. 209-219
-
-
Lewis, H.D.1
Leveridge, M.2
Strack, P.R.3
-
13
-
-
52149123619
-
Core signaling pathways in human pancreatic cancers revealed by global genomic analyses
-
Jones S., Zhang X., Parsons D.W., et al. Core signaling pathways in human pancreatic cancers revealed by global genomic analyses. Science 321 (2008) 1801-1806
-
(2008)
Science
, vol.321
, pp. 1801-1806
-
-
Jones, S.1
Zhang, X.2
Parsons, D.W.3
-
14
-
-
5044225888
-
Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia
-
Weng A.P., Ferrando A.A., Lee W., et al. Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia. Science 306 (2004) 269-271
-
(2004)
Science
, vol.306
, pp. 269-271
-
-
Weng, A.P.1
Ferrando, A.A.2
Lee, W.3
-
15
-
-
34248372925
-
The Nestin progenitor lineage is the compartment of origin for pancreatic intraepithelial neoplasia
-
Carriere C., Seeley E.S., Goetze T., et al. The Nestin progenitor lineage is the compartment of origin for pancreatic intraepithelial neoplasia. Proc Natl Acad Sci U S A 104 (2007) 4437-4442
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 4437-4442
-
-
Carriere, C.1
Seeley, E.S.2
Goetze, T.3
-
16
-
-
57749116315
-
Notch and Kras reprogram pancreatic acinar cells to ductal intraepithelial neoplasia
-
De La O.J.P., Emerson L.L., Goodman J.L., et al. Notch and Kras reprogram pancreatic acinar cells to ductal intraepithelial neoplasia. Proc Natl Acad Sci U S A 105 (2008) 18907-18912
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 18907-18912
-
-
De La, O.J.P.1
Emerson, L.L.2
Goodman, J.L.3
-
17
-
-
57749113202
-
Spontaneous induction of murine pancreatic intraepithelial neoplasia (mPanIN) by acinar cell targeting of oncogenic Kras in adult mice
-
Habbe N., Shi G., Meguid R.A., et al. Spontaneous induction of murine pancreatic intraepithelial neoplasia (mPanIN) by acinar cell targeting of oncogenic Kras in adult mice. Proc Natl Acad Sci U S A 105 (2008) 18913-18918
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 18913-18918
-
-
Habbe, N.1
Shi, G.2
Meguid, R.A.3
-
18
-
-
53349178722
-
In vivo reprogramming of adult pancreatic exocrine cells to beta-cells
-
Zhou Q., Brown J., Kanarek A., et al. In vivo reprogramming of adult pancreatic exocrine cells to beta-cells. Nature 455 (2008) 627-632
-
(2008)
Nature
, vol.455
, pp. 627-632
-
-
Zhou, Q.1
Brown, J.2
Kanarek, A.3
-
19
-
-
12944327377
-
In vitro generation of insulin-producing beta cells from adult exocrine pancreatic cells
-
Baeyens L., De Breuck S., Lardon J., et al. In vitro generation of insulin-producing beta cells from adult exocrine pancreatic cells. Diabetologia 48 (2005) 49-57
-
(2005)
Diabetologia
, vol.48
, pp. 49-57
-
-
Baeyens, L.1
De Breuck, S.2
Lardon, J.3
-
20
-
-
27244437951
-
Lineage tracing and characterization of insulin-secreting cells generated from adult pancreatic acinar cells
-
Minami K., Okuno M., Miyawaki K., et al. Lineage tracing and characterization of insulin-secreting cells generated from adult pancreatic acinar cells. Proc Natl Acad Sci U S A 102 (2005) 15116-15121
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 15116-15121
-
-
Minami, K.1
Okuno, M.2
Miyawaki, K.3
-
22
-
-
38649140167
-
Notch signaling is required for exocrine regeneration after acute pancreatitis
-
Siveke J.T., Lubeseder-Martellato C., Lee M., et al. Notch signaling is required for exocrine regeneration after acute pancreatitis. Gastroenterology 134 (2008) 544-555
-
(2008)
Gastroenterology
, vol.134
, pp. 544-555
-
-
Siveke, J.T.1
Lubeseder-Martellato, C.2
Lee, M.3
-
23
-
-
15744400264
-
Recapitulation of elements of embryonic development in adult mouse pancreatic regeneration
-
Jensen J.N., Cameron E., Garay M.V., et al. Recapitulation of elements of embryonic development in adult mouse pancreatic regeneration. Gastroenterology 128 (2005) 728-741
-
(2005)
Gastroenterology
, vol.128
, pp. 728-741
-
-
Jensen, J.N.1
Cameron, E.2
Garay, M.V.3
-
24
-
-
58149336788
-
Gamma-secretase inhibitors reverse glucocorticoid resistance in T cell acute lymphoblastic leukemia
-
Real P.J., Tosello V., Palomero T., et al. Gamma-secretase inhibitors reverse glucocorticoid resistance in T cell acute lymphoblastic leukemia. Nat. Med 15 (2009) 50-58
-
(2009)
Nat. Med
, vol.15
, pp. 50-58
-
-
Real, P.J.1
Tosello, V.2
Palomero, T.3
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