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Volumn 1, Issue C, 2008, Pages 1-27

Metabolic Organization in Plants: A Challenge for the Metabolic Engineer

Author keywords

Constraints based network analysis; Elementary mode analysis; Enzyme regulation; Kinetic modeling; Metabolic compensation; Metabolic control analysis; Metabolic engineering; Metabolic flux analysis; Photosynthetic carbon metabolism; Subcellular compartmentation

Indexed keywords


EID: 65249095663     PISSN: 17550408     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S1755-0408(07)01001-6     Document Type: Review
Times cited : (17)

References (101)
  • 1
    • 0029073522 scopus 로고
    • A membrane-associated form of sucrose synthase and its potential role in synthesis of cellulose and callose in plants
    • Amor Y., Haigler C.H., Johnson S., Wainscott M., and Delmer D.P. A membrane-associated form of sucrose synthase and its potential role in synthesis of cellulose and callose in plants. Proc. Natl. Acad. Sci. USA 92 (1995) 9353-9357
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 9353-9357
    • Amor, Y.1    Haigler, C.H.2    Johnson, S.3    Wainscott, M.4    Delmer, D.P.5
  • 2
    • 0003137662 scopus 로고
    • Compartmentation of plant metabolism
    • Davies D.D. (Ed), Academic Press, New York
    • ap Rees T. Compartmentation of plant metabolism. In: Davies D.D. (Ed). "The Biochemistry of Plants" vol. 12 (1987), Academic Press, New York 87-115
    • (1987) "The Biochemistry of Plants" , vol.12 , pp. 87-115
    • ap Rees, T.1
  • 3
    • 0034995375 scopus 로고    scopus 로고
    • Complex biology with no parameters
    • Bailey J.E. Complex biology with no parameters. Nat. Biotechnol. 19 (2001) 503-504
    • (2001) Nat. Biotechnol. , vol.19 , pp. 503-504
    • Bailey, J.E.1
  • 5
    • 24044476656 scopus 로고    scopus 로고
    • Response to Neuhaus et al.: No need to shift the paradigm on the pathway to transitory starch in leaves
    • Baroja-Fernandez E., Munoz F.J., and Pozueta-Romero J. Response to Neuhaus et al.: No need to shift the paradigm on the pathway to transitory starch in leaves. Trends Plant Sci. 10 (2005) 156-158
    • (2005) Trends Plant Sci. , vol.10 , pp. 156-158
    • Baroja-Fernandez, E.1    Munoz, F.J.2    Pozueta-Romero, J.3
  • 6
    • 0030804853 scopus 로고    scopus 로고
    • Flux analysis of underdetermined metabolic networks: The quest for the missing constraints
    • Bonarius H.P.J., Schmid G., and Tramper J. Flux analysis of underdetermined metabolic networks: The quest for the missing constraints. Trends Biotechnol. 15 (1997) 308-314
    • (1997) Trends Biotechnol. , vol.15 , pp. 308-314
    • Bonarius, H.P.J.1    Schmid, G.2    Tramper, J.3
  • 8
    • 0036852074 scopus 로고    scopus 로고
    • Characterization of the genes encoding the cytosolic and plastidial forms of ADP-glucose pyrophosphorylase in wheat endosperm
    • Burton R.A., Johnson P.E., Beckles D.M., Fincher G.B., Jenner H.L., Naldrett M.J., and Denyer K. Characterization of the genes encoding the cytosolic and plastidial forms of ADP-glucose pyrophosphorylase in wheat endosperm. Plant Physiol. 130 (2002) 1464-1475
    • (2002) Plant Physiol. , vol.130 , pp. 1464-1475
    • Burton, R.A.1    Johnson, P.E.2    Beckles, D.M.3    Fincher, G.B.4    Jenner, H.L.5    Naldrett, M.J.6    Denyer, K.7
  • 9
    • 0037078975 scopus 로고    scopus 로고
    • Metabolic balance sheets
    • Cornish-Bowden A., and Cardenas M.L. Metabolic balance sheets. Nature 420 (2002) 129-130
    • (2002) Nature , vol.420 , pp. 129-130
    • Cornish-Bowden, A.1    Cardenas, M.L.2
  • 10
    • 0037008673 scopus 로고    scopus 로고
    • Transcriptional regulation in constraints-based metabolic models of Escherichia coli
    • Covert M.W., and Palsson B.O. Transcriptional regulation in constraints-based metabolic models of Escherichia coli. J. Biol. Chem. 277 (2002) 28058-28064
    • (2002) J. Biol. Chem. , vol.277 , pp. 28058-28064
    • Covert, M.W.1    Palsson, B.O.2
  • 12
    • 0002317514 scopus 로고    scopus 로고
    • Natural products (Secondary metabolites)
    • Buchanan B.B., Gruissem W., and Jones R.L. (Eds), American Society of Plant Physiologists, Rockville
    • Croteau R., Kutchan T.M., and Lewis N.G. Natural products (Secondary metabolites). In: Buchanan B.B., Gruissem W., and Jones R.L. (Eds). "Biochemistry & Molecular Biology of Plants" (2000), American Society of Plant Physiologists, Rockville 1250-1318
    • (2000) "Biochemistry & Molecular Biology of Plants" , pp. 1250-1318
    • Croteau, R.1    Kutchan, T.M.2    Lewis, N.G.3
  • 13
    • 0032741030 scopus 로고    scopus 로고
    • Subcellular distribution of enzymes of the oxidative pentose phosphate pathway in root and leaf tissues
    • Debnam P.M., and Emes M.J. Subcellular distribution of enzymes of the oxidative pentose phosphate pathway in root and leaf tissues. J. Exp. Bot. 50 (1999) 1653-1661
    • (1999) J. Exp. Bot. , vol.50 , pp. 1653-1661
    • Debnam, P.M.1    Emes, M.J.2
  • 14
    • 0030267532 scopus 로고    scopus 로고
    • The major form of ADP-glucose pyrophosphorylase in maize endosperm is extra-plastidial
    • Denyer K., Dunlap F., Thorbjornsen T., Keeling P., and Smith A.M. The major form of ADP-glucose pyrophosphorylase in maize endosperm is extra-plastidial. Plant Physiol. 112 (1996) 779-785
    • (1996) Plant Physiol. , vol.112 , pp. 779-785
    • Denyer, K.1    Dunlap, F.2    Thorbjornsen, T.3    Keeling, P.4    Smith, A.M.5
  • 16
    • 0031401175 scopus 로고    scopus 로고
    • Sugar-starvation-induced changes of carbon metabolism in excised maize root tips
    • Dieuaide-Noubhani M., Canioni P., and Raymond P. Sugar-starvation-induced changes of carbon metabolism in excised maize root tips. Plant Physiol. 115 (1997) 1505-1513
    • (1997) Plant Physiol. , vol.115 , pp. 1505-1513
    • Dieuaide-Noubhani, M.1    Canioni, P.2    Raymond, P.3
  • 17
    • 0037355426 scopus 로고    scopus 로고
    • Legume natural products: Understanding and manipulating complex pathways for human and animal health
    • Dixon R.A., and Sumner L.W. Legume natural products: Understanding and manipulating complex pathways for human and animal health. Plant Physiol. 131 (2003) 878-885
    • (2003) Plant Physiol. , vol.131 , pp. 878-885
    • Dixon, R.A.1    Sumner, L.W.2
  • 18
    • 0034519221 scopus 로고    scopus 로고
    • Robustness analysis of the Escherichia coli metabolic network
    • Edwards J.S., and Palsson B.O. Robustness analysis of the Escherichia coli metabolic network. Biotechnol. Prog. 16 (2000) 927-939
    • (2000) Biotechnol. Prog. , vol.16 , pp. 927-939
    • Edwards, J.S.1    Palsson, B.O.2
  • 19
    • 0034625143 scopus 로고    scopus 로고
    • The Escherichia coli MG1655 in silico metabolic genotype: Its definition, characteristics, and capabilities
    • Edwards J.S., and Palsson B.O. The Escherichia coli MG1655 in silico metabolic genotype: Its definition, characteristics, and capabilities. Proc. Natl. Acad. Sci. USA 97 (2000) 5528-5533
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 5528-5533
    • Edwards, J.S.1    Palsson, B.O.2
  • 20
    • 0035125986 scopus 로고    scopus 로고
    • In silico predictions of Escherichia coli metabolic capabilities are consistent with experimental data
    • Edwards J.S., Ibarra R.U., and Palsson B.O. In silico predictions of Escherichia coli metabolic capabilities are consistent with experimental data. Nat. Biotechnol. 19 (2001) 125-130
    • (2001) Nat. Biotechnol. , vol.19 , pp. 125-130
    • Edwards, J.S.1    Ibarra, R.U.2    Palsson, B.O.3
  • 21
    • 0000766251 scopus 로고    scopus 로고
    • Contribution of malic enzyme, pyruvate kinase, phosphoenolpyruvate carboxylase and the Krebs cycle to respiration and biosynthesis and to intracellular pH regulation during hypoxia in maize root tips observed by nuclear magnetic resonance and gas chromatography-mass spectrometry
    • Edwards S., Nguyen B.-T., Do B., and Roberts J.K.M. Contribution of malic enzyme, pyruvate kinase, phosphoenolpyruvate carboxylase and the Krebs cycle to respiration and biosynthesis and to intracellular pH regulation during hypoxia in maize root tips observed by nuclear magnetic resonance and gas chromatography-mass spectrometry. Plant Physiol. 116 (1998) 1073-1081
    • (1998) Plant Physiol. , vol.116 , pp. 1073-1081
    • Edwards, S.1    Nguyen, B.-T.2    Do, B.3    Roberts, J.K.M.4
  • 24
    • 21244477594 scopus 로고    scopus 로고
    • k-cone analysis: Determining all candidate values for kinetic parameters on a network scale
    • Famili I., Mahadevan R., and Palsson B.O. k-cone analysis: Determining all candidate values for kinetic parameters on a network scale. Biophys. J. 88 (2005) 1616-1625
    • (2005) Biophys. J. , vol.88 , pp. 1616-1625
    • Famili, I.1    Mahadevan, R.2    Palsson, B.O.3
  • 26
    • 0034778216 scopus 로고    scopus 로고
    • Analysis of the compartmentation of glycolytic intermediates, nucleotides, sugars, organic acids, amino acids and sugar alcohols in potato tubers using a nonaqueous fractionation method
    • Farré E.M., Tiessen A., Roessner U., Geigenberger P., Trethewey R.N., and Willmitzer L. Analysis of the compartmentation of glycolytic intermediates, nucleotides, sugars, organic acids, amino acids and sugar alcohols in potato tubers using a nonaqueous fractionation method. Plant Physiol. 127 (2001) 685-700
    • (2001) Plant Physiol. , vol.127 , pp. 685-700
    • Farré, E.M.1    Tiessen, A.2    Roessner, U.3    Geigenberger, P.4    Trethewey, R.N.5    Willmitzer, L.6
  • 28
    • 0035121892 scopus 로고    scopus 로고
    • Fructose 2,6-bisphosphate activates pyrophosphate: fructose-6-phosphate 1-phosphotransferase and increases triose phosphate to hexose phosphate cycling in heterotrophic cells
    • Fernie A.R., Roscher A., Ratcliffe R.G., and Kruger N.J. Fructose 2,6-bisphosphate activates pyrophosphate: fructose-6-phosphate 1-phosphotransferase and increases triose phosphate to hexose phosphate cycling in heterotrophic cells. Planta 212 (2001) 250-263
    • (2001) Planta , vol.212 , pp. 250-263
    • Fernie, A.R.1    Roscher, A.2    Ratcliffe, R.G.3    Kruger, N.J.4
  • 29
    • 0036856638 scopus 로고    scopus 로고
    • Potato plants exhibiting combined antisense repression of cytosolic and plastidial isoforms of phosphoglucomutase surprisingly approximate wild type with respect to the rate of starch synthesis. Plant Physiol
    • Fernie A.R., Swiedrych A., Tauberger E., Lytovchenko A., Trethewey R.N., and Willmitzer L. Potato plants exhibiting combined antisense repression of cytosolic and plastidial isoforms of phosphoglucomutase surprisingly approximate wild type with respect to the rate of starch synthesis. Plant Physiol. Biochem. 40 (2002) 921-927
    • (2002) Biochem. , vol.40 , pp. 921-927
    • Fernie, A.R.1    Swiedrych, A.2    Tauberger, E.3    Lytovchenko, A.4    Trethewey, R.N.5    Willmitzer, L.6
  • 31
    • 0034119624 scopus 로고    scopus 로고
    • Mathematical modeling of metabolism
    • Giersch C. Mathematical modeling of metabolism. Curr. Opin. Plant. Biol. 3 (2000) 249-253
    • (2000) Curr. Opin. Plant. Biol. , vol.3 , pp. 249-253
    • Giersch, C.1
  • 32
    • 0032052674 scopus 로고    scopus 로고
    • A moderate decrease of plastid aldolase activity inhibits photosynthesis, alters the levels of sugars and starch, and inhibits growth of potato plants
    • Haake V., Zrenner R., Sonnewald U., and Stitt M. A moderate decrease of plastid aldolase activity inhibits photosynthesis, alters the levels of sugars and starch, and inhibits growth of potato plants. Plant J. 14 (1998) 147-157
    • (1998) Plant J. , vol.14 , pp. 147-157
    • Haake, V.1    Zrenner, R.2    Sonnewald, U.3    Stitt, M.4
  • 33
    • 0032950233 scopus 로고    scopus 로고
    • Changes in aldolase activity in wild-type potato plants are important for acclimation to growth irradiance and carbon dioxide concentration, because plastid aldolase exerts control over the ambient rate of photosynthesis across a range of growth conditions
    • Haake V., Geiger M., Walch-Liu P., Engels C., Zrenner R., and Stitt M. Changes in aldolase activity in wild-type potato plants are important for acclimation to growth irradiance and carbon dioxide concentration, because plastid aldolase exerts control over the ambient rate of photosynthesis across a range of growth conditions. Plant J. 17 (1999) 479-489
    • (1999) Plant J. , vol.17 , pp. 479-489
    • Haake, V.1    Geiger, M.2    Walch-Liu, P.3    Engels, C.4    Zrenner, R.5    Stitt, M.6
  • 35
    • 0031929442 scopus 로고    scopus 로고
    • Reduced sedoheptulose-1,7-bisphosphatase levels in transgenic tobacco lead to decreased photosynthetic capacity and altered carbohydrate accumulation
    • Harrison E.P., Willingham N.M., Lloyd J.C., and Raines C.A. Reduced sedoheptulose-1,7-bisphosphatase levels in transgenic tobacco lead to decreased photosynthetic capacity and altered carbohydrate accumulation. Planta 204 (1998) 27-36
    • (1998) Planta , vol.204 , pp. 27-36
    • Harrison, E.P.1    Willingham, N.M.2    Lloyd, J.C.3    Raines, C.A.4
  • 36
    • 0035059568 scopus 로고    scopus 로고
    • A small decrease of plastid transketolase expression in antisense tobacco transformants has dramatic effects on photosynthesis and phenylpropanoid metabolism
    • Henkes S., Flachmann R., Sonnewald U., and Stitt M.A. A small decrease of plastid transketolase expression in antisense tobacco transformants has dramatic effects on photosynthesis and phenylpropanoid metabolism. Plant Cell 13 (2001) 535-551
    • (2001) Plant Cell , vol.13 , pp. 535-551
    • Henkes, S.1    Flachmann, R.2    Sonnewald, U.3    Stitt, M.A.4
  • 39
    • 0037308505 scopus 로고    scopus 로고
    • Two approaches for metabolic pathway analysis?
    • Klamt S., and Stelling J. Two approaches for metabolic pathway analysis?. Trends Biotechnol. 21 (2003) 64-69
    • (2003) Trends Biotechnol. , vol.21 , pp. 64-69
    • Klamt, S.1    Stelling, J.2
  • 40
    • 0033868442 scopus 로고    scopus 로고
    • Regulation of nitrate reductase expression in leaves by nitrate and nitrogen metabolism is completely overridden when sugars fall below a critical level
    • Klein D., Morcuende R., Stitt M., and Krapp A. Regulation of nitrate reductase expression in leaves by nitrate and nitrogen metabolism is completely overridden when sugars fall below a critical level. Plant Cell Environ. 23 (2000) 863-871
    • (2000) Plant Cell Environ. , vol.23 , pp. 863-871
    • Klein, D.1    Morcuende, R.2    Stitt, M.3    Krapp, A.4
  • 41
  • 42
    • 0037008196 scopus 로고    scopus 로고
    • In vivo and in vitro phosphorylation of membrane and soluble forms of soybean nodule sucrose synthase
    • Komina O., Zhou Y., Sarath G., and Chollet R. In vivo and in vitro phosphorylation of membrane and soluble forms of soybean nodule sucrose synthase. Plant Physiol. 129 (2002) 1664-1673
    • (2002) Plant Physiol. , vol.129 , pp. 1664-1673
    • Komina, O.1    Zhou, Y.2    Sarath, G.3    Chollet, R.4
  • 43
    • 0028084170 scopus 로고
    • Reduction of the chloroplastic fructose-1,6-bisphosphatase in transgenic potato plants impairs photosynthesis and plant growth
    • Kossmann J., Sonnewald U., and Willmitzer L. Reduction of the chloroplastic fructose-1,6-bisphosphatase in transgenic potato plants impairs photosynthesis and plant growth. Plant J. 6 (1994) 637-650
    • (1994) Plant J. , vol.6 , pp. 637-650
    • Kossmann, J.1    Sonnewald, U.2    Willmitzer, L.3
  • 44
    • 2342606425 scopus 로고    scopus 로고
    • Quantitative approaches for analysing fluxes through plant metabolic networks using NMR and stable isotope labelling
    • Kruger N.J., Ratcliffe R.G., and Roscher A. Quantitative approaches for analysing fluxes through plant metabolic networks using NMR and stable isotope labelling. Phytochem. Rev. 2 (2003) 17-30
    • (2003) Phytochem. Rev. , vol.2 , pp. 17-30
    • Kruger, N.J.1    Ratcliffe, R.G.2    Roscher, A.3
  • 45
    • 0037795745 scopus 로고    scopus 로고
    • The oxidative pentose phosphate pathway: Structure and organisation
    • Kruger N.J., and Von Schaewen A. The oxidative pentose phosphate pathway: Structure and organisation. Curr. Opin. Plant. Biol. 6 (2003) 236-246
    • (2003) Curr. Opin. Plant. Biol. , vol.6 , pp. 236-246
    • Kruger, N.J.1    Von Schaewen, A.2
  • 46
    • 0038420709 scopus 로고    scopus 로고
    • Different kinetic and regulatory properties of soluble and membrane-bound nitrate reductases in tomato leaves
    • Lo Piero A.R., Cultrone A., Monachello D., and Petrone G. Different kinetic and regulatory properties of soluble and membrane-bound nitrate reductases in tomato leaves. Plant Sci. 165 (2003) 139-145
    • (2003) Plant Sci. , vol.165 , pp. 139-145
    • Lo Piero, A.R.1    Cultrone, A.2    Monachello, D.3    Petrone, G.4
  • 47
    • 0342797825 scopus 로고    scopus 로고
    • The reductive pentose phosphate pathway and its regulation
    • Dennis D.T., Turpin D.H., Lefebvre D.D., and Layzell D.B. (Eds), Longman, Harlow
    • Macdonald F.D., and Buchanan B.B. The reductive pentose phosphate pathway and its regulation. In: Dennis D.T., Turpin D.H., Lefebvre D.D., and Layzell D.B. (Eds). "Plant Metabolism" (1997), Longman, Harlow 299-313
    • (1997) "Plant Metabolism" , pp. 299-313
    • Macdonald, F.D.1    Buchanan, B.B.2
  • 48
    • 0032600814 scopus 로고    scopus 로고
    • Response of the central metabolism in Corynebacterium glutamicum to the use of an NADH-dependent glutamate dehydrogenase
    • Marx A., Eikmanns B.J., Sahm H., De Graaf A.A., and Eggeling L. Response of the central metabolism in Corynebacterium glutamicum to the use of an NADH-dependent glutamate dehydrogenase. Metab. Eng. 1 (1999) 35-48
    • (1999) Metab. Eng. , vol.1 , pp. 35-48
    • Marx, A.1    Eikmanns, B.J.2    Sahm, H.3    De Graaf, A.A.4    Eggeling, L.5
  • 49
    • 0036017869 scopus 로고    scopus 로고
    • Decreased Rubisco activity leads to dramatic changes of nitrate metabolism, amino acid metabolism and the levels of phenylpropanoids and nicotine in tobacco antisense RBCS transformants
    • Matt P., Krapp A., Haake V., Mock H.P., and Stitt M. Decreased Rubisco activity leads to dramatic changes of nitrate metabolism, amino acid metabolism and the levels of phenylpropanoids and nicotine in tobacco antisense RBCS transformants. Plant J. 30 (2002) 663-677
    • (2002) Plant J. , vol.30 , pp. 663-677
    • Matt, P.1    Krapp, A.2    Haake, V.3    Mock, H.P.4    Stitt, M.5
  • 50
    • 0034079640 scopus 로고    scopus 로고
    • Radiotracer and computer modelling evidence that phospho-base methylation is the main route of choline synthesis in tobacco
    • McNeil S.D., Nuccio M.L., Rhodes D., Shachar-Hill Y., and Hanson A.D. Radiotracer and computer modelling evidence that phospho-base methylation is the main route of choline synthesis in tobacco. Plant Physiol. 123 (2000) 371-380
    • (2000) Plant Physiol. , vol.123 , pp. 371-380
    • McNeil, S.D.1    Nuccio, M.L.2    Rhodes, D.3    Shachar-Hill, Y.4    Hanson, A.D.5
  • 51
    • 0033829610 scopus 로고    scopus 로고
    • Metabolic modelling identifies key constraints on an engineered glycine betaine synthesis pathway in tobacco
    • McNeil S.D., Rhodes D., Russell B.L., Nuccio M.L., Shachar-Hill Y., and Hanson A.D. Metabolic modelling identifies key constraints on an engineered glycine betaine synthesis pathway in tobacco. Plant Physiol. 124 (2000) 153-162
    • (2000) Plant Physiol. , vol.124 , pp. 153-162
    • McNeil, S.D.1    Rhodes, D.2    Russell, B.L.3    Nuccio, M.L.4    Shachar-Hill, Y.5    Hanson, A.D.6
  • 52
    • 0038613748 scopus 로고    scopus 로고
    • Plant biotechnology and breeding: Allied for years to come
    • Morandini P., and Salamini F. Plant biotechnology and breeding: Allied for years to come. Trends Plant Sci. 8 (2003) 70-75
    • (2003) Trends Plant Sci. , vol.8 , pp. 70-75
    • Morandini, P.1    Salamini, F.2
  • 53
    • 0036336088 scopus 로고    scopus 로고
    • Mathematical modelling of plant metabolic pathways
    • Morgan J.A., and Rhodes D. Mathematical modelling of plant metabolic pathways. Metab. Eng. 4 (2002) 80-89
    • (2002) Metab. Eng. , vol.4 , pp. 80-89
    • Morgan, J.A.1    Rhodes, D.2
  • 57
    • 85102984110 scopus 로고    scopus 로고
    • No need to shift the paradigm on the pathway to transitory starch in leaves
    • Neuhaus H.E., Häusler R.E., and Sonnewald U. No need to shift the paradigm on the pathway to transitory starch in leaves. Trends Plant Sci. 10 (2005) 154-156
    • (2005) Trends Plant Sci. , vol.10 , pp. 154-156
    • Neuhaus, H.E.1    Häusler, R.E.2    Sonnewald, U.3
  • 58
    • 0026782902 scopus 로고
    • A strategy for increasing an in vivo flux by genetic manipulations-the tryptophan system of yeast
    • Niederberger P., Prasad R., Miozzari G., and Kacser H. A strategy for increasing an in vivo flux by genetic manipulations-the tryptophan system of yeast. Biochem. J. 287 (1992) 473-479
    • (1992) Biochem. J. , vol.287 , pp. 473-479
    • Niederberger, P.1    Prasad, R.2    Miozzari, G.3    Kacser, H.4
  • 59
    • 0034008457 scopus 로고    scopus 로고
    • Gene expression profiling by DNA microarrays and metabolic fluxes in Escherichia coli
    • Oh M.-K., and Liao J.C. Gene expression profiling by DNA microarrays and metabolic fluxes in Escherichia coli. Biotechnol. Prog. 16 (2000) 278-286
    • (2000) Biotechnol. Prog. , vol.16 , pp. 278-286
    • Oh, M.-K.1    Liao, J.C.2
  • 60
    • 0037066717 scopus 로고    scopus 로고
    • Global expression profiling of acetate grown Escherichia coli
    • Oh M.-K., Rohlin L., Kao K.C., and Liao J.C. Global expression profiling of acetate grown Escherichia coli. J. Biol. Chem. 277 (2002) 13175-13183
    • (2002) J. Biol. Chem. , vol.277 , pp. 13175-13183
    • Oh, M.-K.1    Rohlin, L.2    Kao, K.C.3    Liao, J.C.4
  • 61
    • 0037019153 scopus 로고    scopus 로고
    • Demand management in cells
    • Oliver S. Demand management in cells. Nature 418 (2002) 33-34
    • (2002) Nature , vol.418 , pp. 33-34
    • Oliver, S.1
  • 64
    • 0034680782 scopus 로고    scopus 로고
    • In vivo quantification of parallel and bidirectional fluxes in the anaplerosis of Corynebacterium glutamicum
    • Petersen S., De Graaf A.A., Eggeling L., Möllney M., Wiechert W., and Sahm H. In vivo quantification of parallel and bidirectional fluxes in the anaplerosis of Corynebacterium glutamicum. J. Biol. Chem. 275 (2000) 35932-35941
    • (2000) J. Biol. Chem. , vol.275 , pp. 35932-35941
    • Petersen, S.1    De Graaf, A.A.2    Eggeling, L.3    Möllney, M.4    Wiechert, W.5    Sahm, H.6
  • 65
    • 0035212573 scopus 로고    scopus 로고
    • Metabolic consequences of altered phosphoenolpyruvate carboxykinase activity in Corynebacterium glutamicum reveal anaplerotic regulation mechanisms in vivo
    • Petersen S., Mack C., De Graaf A.A., Riedel C., Eikmanns B.J., and Sahm H. Metabolic consequences of altered phosphoenolpyruvate carboxykinase activity in Corynebacterium glutamicum reveal anaplerotic regulation mechanisms in vivo. Metab. Eng. 3 (2001) 344-361
    • (2001) Metab. Eng. , vol.3 , pp. 344-361
    • Petersen, S.1    Mack, C.2    De Graaf, A.A.3    Riedel, C.4    Eikmanns, B.J.5    Sahm, H.6
  • 66
    • 1542350574 scopus 로고    scopus 로고
    • The growing family of mitochondrial carriers in Arabidopsis
    • Picault N., Hodges M., Palmieri L., and Palmieri F. The growing family of mitochondrial carriers in Arabidopsis. Trends Plant Sci. 9 (2004) 138-146
    • (2004) Trends Plant Sci. , vol.9 , pp. 138-146
    • Picault, N.1    Hodges, M.2    Palmieri, L.3    Palmieri, F.4
  • 67
    • 0033975578 scopus 로고    scopus 로고
    • Modelling photosynthesis and its control
    • Poolman M.G., Fell D.A., and Thomas S. Modelling photosynthesis and its control. J. Exp. Bot. 51 (2000) 319-328
    • (2000) J. Exp. Bot. , vol.51 , pp. 319-328
    • Poolman, M.G.1    Fell, D.A.2    Thomas, S.3
  • 68
    • 0037317848 scopus 로고    scopus 로고
    • Elementary modes analysis of photosynthate metabolism in the chloroplast stroma
    • Poolman M.G., Fell D.A., and Raines C.A. Elementary modes analysis of photosynthate metabolism in the chloroplast stroma. Eur. J. Biochem. 270 (2003) 430-439
    • (2003) Eur. J. Biochem. , vol.270 , pp. 430-439
    • Poolman, M.G.1    Fell, D.A.2    Raines, C.A.3
  • 69
    • 0037385718 scopus 로고    scopus 로고
    • Genome-scale microbial in silico models: The constraints-based approach
    • Price N.D., Papin J.A., Schilling C.H., and Palsson B.O. Genome-scale microbial in silico models: The constraints-based approach. Trends Biotechnol. 21 (2003) 162-169
    • (2003) Trends Biotechnol. , vol.21 , pp. 162-169
    • Price, N.D.1    Papin, J.A.2    Schilling, C.H.3    Palsson, B.O.4
  • 70
    • 9544253891 scopus 로고    scopus 로고
    • Genome-scale models of microbial cells: Evaluating the consequences of constraints
    • Price N.D., Reed J.L., and Palsson B.O. Genome-scale models of microbial cells: Evaluating the consequences of constraints. Nat. Rev. Microbiol. 2 (2004) 886-897
    • (2004) Nat. Rev. Microbiol. , vol.2 , pp. 886-897
    • Price, N.D.1    Reed, J.L.2    Palsson, B.O.3
  • 71
    • 0036038886 scopus 로고    scopus 로고
    • Schemes of flux control in a model of Saccharomyces cerevisiae glycolysis
    • Pritchard L., and Kell D.B. Schemes of flux control in a model of Saccharomyces cerevisiae glycolysis. Eur. J. Biochem. 269 (2002) 3894-3904
    • (2002) Eur. J. Biochem. , vol.269 , pp. 3894-3904
    • Pritchard, L.1    Kell, D.B.2
  • 72
    • 33644853940 scopus 로고    scopus 로고
    • Measuring multiple fluxes through plant metabolic networks
    • Ratcliffe R.G., and Shachar-Hill Y. Measuring multiple fluxes through plant metabolic networks. Plant J. 45 (2006) 490-511
    • (2006) Plant J. , vol.45 , pp. 490-511
    • Ratcliffe, R.G.1    Shachar-Hill, Y.2
  • 74
    • 0037113867 scopus 로고    scopus 로고
    • The metabolic architecture of plant cells. Stability of central metabolism and flexibility of anabolic pathways during the growth cycle of tomato cells
    • Rontein D., Dieuaide-Noubhani M., Dufourc E.J., Raymond P., and Rolin D. The metabolic architecture of plant cells. Stability of central metabolism and flexibility of anabolic pathways during the growth cycle of tomato cells. J. Biol. Chem. 277 (2002) 43948-43960
    • (2002) J. Biol. Chem. , vol.277 , pp. 43948-43960
    • Rontein, D.1    Dieuaide-Noubhani, M.2    Dufourc, E.J.3    Raymond, P.4    Rolin, D.5
  • 75
    • 0033979908 scopus 로고    scopus 로고
    • Strategies for metabolic flux analysis in plants using stable isotope labelling
    • Roscher A., Kruger N.J., and Ratcliffe R.G. Strategies for metabolic flux analysis in plants using stable isotope labelling. J. Biotechnol. 77 (2000) 81-102
    • (2000) J. Biotechnol. , vol.77 , pp. 81-102
    • Roscher, A.1    Kruger, N.J.2    Ratcliffe, R.G.3
  • 76
    • 0034951257 scopus 로고    scopus 로고
    • Co-ordinate regulation of genes involved in storage lipid mobilization in Arabidopsis thaliana
    • Rylott E.L., Hooks M.A., and Graham I.A. Co-ordinate regulation of genes involved in storage lipid mobilization in Arabidopsis thaliana. Biochem. Soc. Trans. 29 (2001) 283-287
    • (2001) Biochem. Soc. Trans. , vol.29 , pp. 283-287
    • Rylott, E.L.1    Hooks, M.A.2    Graham, I.A.3
  • 77
    • 0032753923 scopus 로고    scopus 로고
    • Metabolic flux ratio analysis of genetic and environmental modulations of Escherichia coli central metabolism
    • Sauer U., Lasko D.R., Fiaux J., Hochuli M., Glaser R., Szyperski T., Wüthrich K., and Bailey J.E. Metabolic flux ratio analysis of genetic and environmental modulations of Escherichia coli central metabolism. J. Bacteriol. 181 (1999) 6679-6688
    • (1999) J. Bacteriol. , vol.181 , pp. 6679-6688
    • Sauer, U.1    Lasko, D.R.2    Fiaux, J.3    Hochuli, M.4    Glaser, R.5    Szyperski, T.6    Wüthrich, K.7    Bailey, J.E.8
  • 79
    • 0033080396 scopus 로고    scopus 로고
    • Detection of elementary flux modes in biochemical networks: A promising tool for pathway analysis and metabolic engineering
    • Schuster S., Dandekar T., and Fell D.A. Detection of elementary flux modes in biochemical networks: A promising tool for pathway analysis and metabolic engineering. Trends Biotechnol. 17 (1999) 53-60
    • (1999) Trends Biotechnol. , vol.17 , pp. 53-60
    • Schuster, S.1    Dandekar, T.2    Fell, D.A.3
  • 80
    • 0037373214 scopus 로고    scopus 로고
    • Metabolome diversity: Too few genes, too many metabolites
    • Schwab W. Metabolome diversity: Too few genes, too many metabolites. Phytochemistry 62 (2003) 837-849
    • (2003) Phytochemistry , vol.62 , pp. 837-849
    • Schwab, W.1
  • 81
    • 0042531959 scopus 로고    scopus 로고
    • A flux model of glycolysis and the oxidative pentose phosphate pathway in developing Brassica napus embryos
    • Schwender J., Ohlrogge J.B., and Shachar-Hill Y. A flux model of glycolysis and the oxidative pentose phosphate pathway in developing Brassica napus embryos. J. Biol. Chem. 278 (2003) 29442-29453
    • (2003) J. Biol. Chem. , vol.278 , pp. 29442-29453
    • Schwender, J.1    Ohlrogge, J.B.2    Shachar-Hill, Y.3
  • 85
    • 0037079050 scopus 로고    scopus 로고
    • Metabolic network structure determines key aspects of functionality and regulation
    • Stelling J., Klamt S., Bettenbrock K., Schuster S., and Gilles E.D. Metabolic network structure determines key aspects of functionality and regulation. Nature 420 (2002) 190-193
    • (2002) Nature , vol.420 , pp. 190-193
    • Stelling, J.1    Klamt, S.2    Bettenbrock, K.3    Schuster, S.4    Gilles, E.D.5
  • 86
    • 84994971792 scopus 로고
    • Does Rubisco control the rate of photosynthesis and plant growth? An exercise in molecular ecophysiology
    • Stitt M., and Schulze E.-D. Does Rubisco control the rate of photosynthesis and plant growth? An exercise in molecular ecophysiology. Plant Cell Environ. 17 (1994) 465-487
    • (1994) Plant Cell Environ. , vol.17 , pp. 465-487
    • Stitt, M.1    Schulze, E.-D.2
  • 88
    • 0345270397 scopus 로고    scopus 로고
    • Plant metabolomics: Large-scale phytochemistry in the functional genomics era
    • Sumner L.W., Mendes P., and Dixon R.A. Plant metabolomics: Large-scale phytochemistry in the functional genomics era. Phytochemistry 62 (2003) 817-836
    • (2003) Phytochemistry , vol.62 , pp. 817-836
    • Sumner, L.W.1    Mendes, P.2    Dixon, R.A.3
  • 89
    • 0037783266 scopus 로고    scopus 로고
    • Predictive metabolic engineering: A goal for systems biology
    • Sweetlove L.J., Last R.L., and Fernie A.R. Predictive metabolic engineering: A goal for systems biology. Plant Physiol. 132 (2003) 420-425
    • (2003) Plant Physiol. , vol.132 , pp. 420-425
    • Sweetlove, L.J.1    Last, R.L.2    Fernie, A.R.3
  • 90
    • 0031594984 scopus 로고    scopus 로고
    • 13C-NMR, MS and metabolic flux balancing in biotechnology research
    • 13C-NMR, MS and metabolic flux balancing in biotechnology research. Q. Rev. Biophys. 31 (1998) 41-106
    • (1998) Q. Rev. Biophys. , vol.31 , pp. 41-106
    • Szyperski, T.1
  • 91
    • 0035816464 scopus 로고    scopus 로고
    • Transcriptome meets metabolome: Hierarchical and metabolic regulation of the glycolytic pathway
    • ter Kuile B.H., and Westerhoff H.V. Transcriptome meets metabolome: Hierarchical and metabolic regulation of the glycolytic pathway. FEBS Lett. 500 (2001) 169-171
    • (2001) FEBS Lett. , vol.500 , pp. 169-171
    • ter Kuile, B.H.1    Westerhoff, H.V.2
  • 93
    • 0034891035 scopus 로고    scopus 로고
    • Using gene knockouts to investigate plant metabolism
    • Thorneycroft D., Sherson S.M., and Smith S.M. Using gene knockouts to investigate plant metabolism. J. Exp. Bot. 52 (2001) 1593-1601
    • (2001) J. Exp. Bot. , vol.52 , pp. 1593-1601
    • Thorneycroft, D.1    Sherson, S.M.2    Smith, S.M.3
  • 95
    • 0035997009 scopus 로고    scopus 로고
    • Extreme pathway analysis of human red blood cell metabolism
    • Wiback S.J., and Palsson B.O. Extreme pathway analysis of human red blood cell metabolism. Biophys. J. 83 (2002) 808-818
    • (2002) Biophys. J. , vol.83 , pp. 808-818
    • Wiback, S.J.1    Palsson, B.O.2
  • 96
    • 0034741983 scopus 로고    scopus 로고
    • 13C metabolic flux analysis
    • Wiechert W. 13C metabolic flux analysis. Metab. Eng. 3 (2001) 195-206
    • (2001) Metab. Eng. , vol.3 , pp. 195-206
    • Wiechert, W.1
  • 97
    • 0037075690 scopus 로고    scopus 로고
    • Modeling and simulation: Tools for metabolic engineering
    • Wiechert W. Modeling and simulation: Tools for metabolic engineering. J. Biotechnol. 94 (2002) 37-63
    • (2002) J. Biotechnol. , vol.94 , pp. 37-63
    • Wiechert, W.1
  • 99
    • 0033009542 scopus 로고    scopus 로고
    • Kinetic characterization of succinate-dependent plasma membrane-bound nitrate reductase in tobacco roots
    • Wienkoop S., Ullrich W.R., and Stohr C. Kinetic characterization of succinate-dependent plasma membrane-bound nitrate reductase in tobacco roots. Physiol. Plantarum 105 (1999) 609-614
    • (1999) Physiol. Plantarum , vol.105 , pp. 609-614
    • Wienkoop, S.1    Ullrich, W.R.2    Stohr, C.3
  • 101
    • 0029188457 scopus 로고
    • Creation of a metabolic sink for tryptophan alters the phenylpropanoid pathway and the susceptibility of potato to Phytophthora infestans
    • Yao K., De Luca V., and Brisson N. Creation of a metabolic sink for tryptophan alters the phenylpropanoid pathway and the susceptibility of potato to Phytophthora infestans. Plant Cell 7 (1995) 1787-1799
    • (1995) Plant Cell , vol.7 , pp. 1787-1799
    • Yao, K.1    De Luca, V.2    Brisson, N.3


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