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Volumn 19, Issue 5, 2009, Pages 189-197

A post-translational modification code for transcription factors: sorting through a sea of signals

Author keywords

[No Author keywords available]

Indexed keywords

FORKHEAD TRANSCRIPTION FACTOR; HISTONE; TRANSCRIPTION FACTOR;

EID: 65149105339     PISSN: 09628924     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tcb.2009.02.003     Document Type: Article
Times cited : (106)

References (55)
  • 1
    • 0034978579 scopus 로고    scopus 로고
    • Crosstalk and specificity in signalling. Are we crosstalking ourselves into general confusion?
    • Dumont J.E., et al. Crosstalk and specificity in signalling. Are we crosstalking ourselves into general confusion?. Cell. Signal. 13 (2001) 457-463
    • (2001) Cell. Signal. , vol.13 , pp. 457-463
    • Dumont, J.E.1
  • 2
    • 34247850947 scopus 로고    scopus 로고
    • Mathematical models of specificity in cell signaling
    • Bardwell L., et al. Mathematical models of specificity in cell signaling. Biophys. J. 92 (2007) 3425-3441
    • (2007) Biophys. J. , vol.92 , pp. 3425-3441
    • Bardwell, L.1
  • 3
    • 0037223971 scopus 로고    scopus 로고
    • The evolution of signalling pathways in animal development
    • Pires-daSilva A., and Sommer R.J. The evolution of signalling pathways in animal development. Nat. Rev. Genet. 4 (2003) 39-49
    • (2003) Nat. Rev. Genet. , vol.4 , pp. 39-49
    • Pires-daSilva, A.1    Sommer, R.J.2
  • 4
    • 33644853802 scopus 로고    scopus 로고
    • Histone modifications: signalling receptors and potential elements of a heritable epigenetic code
    • Nightingale K.P., et al. Histone modifications: signalling receptors and potential elements of a heritable epigenetic code. Curr. Opin. Genet. Dev. 16 (2006) 125-136
    • (2006) Curr. Opin. Genet. Dev. , vol.16 , pp. 125-136
    • Nightingale, K.P.1
  • 5
    • 44649170303 scopus 로고    scopus 로고
    • Cracking the coregulator codes
    • O'Malley B.W., et al. Cracking the coregulator codes. Curr. Opin. Cell Biol. 20 (2008) 310-315
    • (2008) Curr. Opin. Cell Biol. , vol.20 , pp. 310-315
    • O'Malley, B.W.1
  • 7
    • 34249299791 scopus 로고    scopus 로고
    • The complex language of chromatin regulation during transcription
    • Berger S.L. The complex language of chromatin regulation during transcription. Nature 447 (2007) 407-412
    • (2007) Nature , vol.447 , pp. 407-412
    • Berger, S.L.1
  • 8
    • 33847076849 scopus 로고    scopus 로고
    • Chromatin modifications and their function
    • Kouzarides T. Chromatin modifications and their function. Cell 128 (2007) 693-705
    • (2007) Cell , vol.128 , pp. 693-705
    • Kouzarides, T.1
  • 9
    • 33845877732 scopus 로고    scopus 로고
    • Defining an epigenetic code
    • Turner B.M. Defining an epigenetic code. Nat. Cell Biol. 9 (2007) 2-6
    • (2007) Nat. Cell Biol. , vol.9 , pp. 2-6
    • Turner, B.M.1
  • 10
    • 52449132322 scopus 로고    scopus 로고
    • Is there a code embedded in proteins that is based on post-translational modifications?
    • Sims III R.J., and Reinberg D. Is there a code embedded in proteins that is based on post-translational modifications?. Nat. Rev. Mol. Cell Biol. 9 (2008) 815-820
    • (2008) Nat. Rev. Mol. Cell Biol. , vol.9 , pp. 815-820
    • Sims III, R.J.1    Reinberg, D.2
  • 11
    • 41849128523 scopus 로고    scopus 로고
    • The FoxO code
    • Calnan D.R., and Brunet A. The FoxO code. Oncogene 27 (2008) 2276-2288
    • (2008) Oncogene , vol.27 , pp. 2276-2288
    • Calnan, D.R.1    Brunet, A.2
  • 12
    • 34548830425 scopus 로고    scopus 로고
    • The tubulin code
    • Verhey K.J., and Gaertig J. The tubulin code. Cell Cycle 6 (2007) 2152-2160
    • (2007) Cell Cycle , vol.6 , pp. 2152-2160
    • Verhey, K.J.1    Gaertig, J.2
  • 13
    • 49349107518 scopus 로고    scopus 로고
    • Lysine acetylation: codified crosstalk with other posttranslational modifications
    • Yang X.J., and Seto E. Lysine acetylation: codified crosstalk with other posttranslational modifications. Mol. Cell 31 (2008) 449-461
    • (2008) Mol. Cell , vol.31 , pp. 449-461
    • Yang, X.J.1    Seto, E.2
  • 14
    • 0035839136 scopus 로고    scopus 로고
    • Translating the histone code
    • Jenuwein T., and Allis C.D. Translating the histone code. Science 293 (2001) 1074-1080
    • (2001) Science , vol.293 , pp. 1074-1080
    • Jenuwein, T.1    Allis, C.D.2
  • 15
    • 34047274419 scopus 로고    scopus 로고
    • Global patterns of histone modifications
    • Rando O.J. Global patterns of histone modifications. Curr. Opin. Genet. Dev. 17 (2007) 94-99
    • (2007) Curr. Opin. Genet. Dev. , vol.17 , pp. 94-99
    • Rando, O.J.1
  • 16
    • 33750456519 scopus 로고    scopus 로고
    • Global, in vivo, and site-specific phosphorylation dynamics in signaling networks
    • Olsen J.V., et al. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. Cell 127 (2006) 635-648
    • (2006) Cell , vol.127 , pp. 635-648
    • Olsen, J.V.1
  • 17
    • 36749010218 scopus 로고    scopus 로고
    • The age of crosstalk: phosphorylation, ubiquitination, and beyond
    • Hunter T. The age of crosstalk: phosphorylation, ubiquitination, and beyond. Mol. Cell 28 (2007) 730-738
    • (2007) Mol. Cell , vol.28 , pp. 730-738
    • Hunter, T.1
  • 18
    • 0036566003 scopus 로고    scopus 로고
    • Two novel phosphorylation sites on FKHR that are critical for its nuclear exclusion
    • Rena G., et al. Two novel phosphorylation sites on FKHR that are critical for its nuclear exclusion. EMBO J. 21 (2002) 2263-2271
    • (2002) EMBO J. , vol.21 , pp. 2263-2271
    • Rena, G.1
  • 19
    • 27844497945 scopus 로고    scopus 로고
    • FOXO transcription factors at the interface between longevity and tumor suppression
    • Greer E.L., and Brunet A. FOXO transcription factors at the interface between longevity and tumor suppression. Oncogene 24 (2005) 7410-7425
    • (2005) Oncogene , vol.24 , pp. 7410-7425
    • Greer, E.L.1    Brunet, A.2
  • 20
    • 3542991477 scopus 로고    scopus 로고
    • On mechanisms that control heat shock transcription factor activity in metazoan cells
    • Voellmy R. On mechanisms that control heat shock transcription factor activity in metazoan cells. Cell Stress Chaperones 9 (2004) 122-133
    • (2004) Cell Stress Chaperones , vol.9 , pp. 122-133
    • Voellmy, R.1
  • 21
    • 45749108672 scopus 로고    scopus 로고
    • Integration of global signaling pathways, cAMP-PKA, MAPK and TOR in the regulation of FLO11
    • Vinod P.K., et al. Integration of global signaling pathways, cAMP-PKA, MAPK and TOR in the regulation of FLO11. PLoS ONE 3 (2008) e1663
    • (2008) PLoS ONE , vol.3
    • Vinod, P.K.1
  • 22
    • 37349096366 scopus 로고    scopus 로고
    • FOXO transcription factors in ageing and cancer
    • Greer E.L., and Brunet A. FOXO transcription factors in ageing and cancer. Acta Physiol. (Oxf.) 192 (2008) 19-28
    • (2008) Acta Physiol. (Oxf.) , vol.192 , pp. 19-28
    • Greer, E.L.1    Brunet, A.2
  • 23
    • 41549135942 scopus 로고    scopus 로고
    • FoxO transcription factors in the maintenance of cellular homeostasis during aging
    • Salih D.A., and Brunet A. FoxO transcription factors in the maintenance of cellular homeostasis during aging. Curr. Opin. Cell Biol. 20 (2008) 126-136
    • (2008) Curr. Opin. Cell Biol. , vol.20 , pp. 126-136
    • Salih, D.A.1    Brunet, A.2
  • 24
    • 0038152845 scopus 로고    scopus 로고
    • Suppression of ovarian follicle activation in mice by the transcription factor Foxo3a
    • Castrillon D.H., et al. Suppression of ovarian follicle activation in mice by the transcription factor Foxo3a. Science 301 (2003) 215-218
    • (2003) Science , vol.301 , pp. 215-218
    • Castrillon, D.H.1
  • 25
    • 52949122885 scopus 로고    scopus 로고
    • FOXO3A genotype is strongly associated with human longevity
    • Willcox B.J., et al. FOXO3A genotype is strongly associated with human longevity. Proc. Natl. Acad. Sci. U. S. A. 105 (2008) 13987-13992
    • (2008) Proc. Natl. Acad. Sci. U. S. A. , vol.105 , pp. 13987-13992
    • Willcox, B.J.1
  • 26
    • 62449083712 scopus 로고    scopus 로고
    • Association of FOXO3A variation with human longevity confirmed in German centenarians
    • 10.1073/pnas.0809594106
    • Flachsbart F., et al. Association of FOXO3A variation with human longevity confirmed in German centenarians. Proc. Natl. Acad. Sci. U. S. A. (2009) 10.1073/pnas.0809594106
    • (2009) Proc. Natl. Acad. Sci. U. S. A.
    • Flachsbart, F.1
  • 27
    • 26444511733 scopus 로고    scopus 로고
    • Foxl2 is required for commitment to ovary differentiation
    • Ottolenghi C., et al. Foxl2 is required for commitment to ovary differentiation. Hum. Mol. Genet. 14 (2005) 2053-2062
    • (2005) Hum. Mol. Genet. , vol.14 , pp. 2053-2062
    • Ottolenghi, C.1
  • 28
    • 33847666428 scopus 로고    scopus 로고
    • Potential targets of FOXL2, a transcription factor involved in craniofacial and follicular development, identified by transcriptomics
    • Batista F., et al. Potential targets of FOXL2, a transcription factor involved in craniofacial and follicular development, identified by transcriptomics. Proc. Natl. Acad. Sci. U. S. A. 104 (2007) 3330-3335
    • (2007) Proc. Natl. Acad. Sci. U. S. A. , vol.104 , pp. 3330-3335
    • Batista, F.1
  • 29
    • 39149117672 scopus 로고    scopus 로고
    • The mutations and potential targets of the forkhead transcription factor FOXL2
    • Moumne L., et al. The mutations and potential targets of the forkhead transcription factor FOXL2. Mol. Cell. Endocrinol. 282 (2008) 2-11
    • (2008) Mol. Cell. Endocrinol. , vol.282 , pp. 2-11
    • Moumne, L.1
  • 30
    • 58949102956 scopus 로고    scopus 로고
    • Positive and negative feedback regulates the transcription factor FOXL2 in response to cell stress: evidence for a regulatory imbalance induced by disease-causing mutations
    • Benayoun B.A., et al. Positive and negative feedback regulates the transcription factor FOXL2 in response to cell stress: evidence for a regulatory imbalance induced by disease-causing mutations. Hum. Mol. Genet. 18 (2009) 632-644
    • (2009) Hum. Mol. Genet. , vol.18 , pp. 632-644
    • Benayoun, B.A.1
  • 31
    • 34848861463 scopus 로고    scopus 로고
    • The energy sensor AMP-activated protein kinase directly regulates the mammalian FOXO3 transcription factor
    • Greer E.L., et al. The energy sensor AMP-activated protein kinase directly regulates the mammalian FOXO3 transcription factor. J. Biol. Chem. 282 (2007) 30107-30119
    • (2007) J. Biol. Chem. , vol.282 , pp. 30107-30119
    • Greer, E.L.1
  • 32
    • 55249105738 scopus 로고    scopus 로고
    • FoxO3a mediates transforming growth factor-β1-induced apoptosis in FaO rat hepatoma cells
    • Kim B.C. FoxO3a mediates transforming growth factor-β1-induced apoptosis in FaO rat hepatoma cells. BMB Rep. 41 (2008) 728-732
    • (2008) BMB Rep. , vol.41 , pp. 728-732
    • Kim, B.C.1
  • 33
    • 34249281690 scopus 로고    scopus 로고
    • Stressing the role of FoxO proteins in lifespan and disease
    • van der Horst A., and Burgering B.M. Stressing the role of FoxO proteins in lifespan and disease. Nat. Rev. Mol. Cell Biol. 8 (2007) 440-450
    • (2007) Nat. Rev. Mol. Cell Biol. , vol.8 , pp. 440-450
    • van der Horst, A.1    Burgering, B.M.2
  • 34
    • 11244320393 scopus 로고    scopus 로고
    • FOXO transcription factor activation by oxidative stress mediated by the small GTPase Ral and JNK
    • Essers M.A., et al. FOXO transcription factor activation by oxidative stress mediated by the small GTPase Ral and JNK. EMBO J. 23 (2004) 4802-4812
    • (2004) EMBO J. , vol.23 , pp. 4802-4812
    • Essers, M.A.1
  • 35
    • 0033582929 scopus 로고    scopus 로고
    • Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor
    • Brunet A., et al. Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor. Cell 96 (1999) 857-868
    • (1999) Cell , vol.96 , pp. 857-868
    • Brunet, A.1
  • 36
    • 53349176609 scopus 로고    scopus 로고
    • The identification and characterization of a FOXL2 response element provides insights into the pathogenesis of mutant alleles
    • Benayoun B.A., et al. The identification and characterization of a FOXL2 response element provides insights into the pathogenesis of mutant alleles. Hum. Mol. Genet. 17 (2008) 3118-3127
    • (2008) Hum. Mol. Genet. , vol.17 , pp. 3118-3127
    • Benayoun, B.A.1
  • 37
    • 36749079110 scopus 로고    scopus 로고
    • Crystal structure of the human FOXO3a-DBD/DNA complex suggests the effects of post-translational modification
    • Tsai K.L., et al. Crystal structure of the human FOXO3a-DBD/DNA complex suggests the effects of post-translational modification. Nucleic Acids Res. 35 (2007) 6984-6994
    • (2007) Nucleic Acids Res. , vol.35 , pp. 6984-6994
    • Tsai, K.L.1
  • 38
    • 50849130900 scopus 로고    scopus 로고
    • Structural basis for DNA recognition by FoxO1 and its regulation by posttranslational modification
    • Brent M.M., et al. Structural basis for DNA recognition by FoxO1 and its regulation by posttranslational modification. Structure 16 (2008) 1407-1416
    • (2008) Structure , vol.16 , pp. 1407-1416
    • Brent, M.M.1
  • 39
    • 49749095091 scopus 로고    scopus 로고
    • The post-translational modification profile of the forkhead transcription factor FOXL2 suggests the existence of parallel processive/concerted modification pathways
    • Benayoun B.A., et al. The post-translational modification profile of the forkhead transcription factor FOXL2 suggests the existence of parallel processive/concerted modification pathways. Proteomics 8 (2008) 3118-3123
    • (2008) Proteomics , vol.8 , pp. 3118-3123
    • Benayoun, B.A.1
  • 40
    • 0034818446 scopus 로고    scopus 로고
    • Post-translational modifications and activation of p53 by genotoxic stresses
    • Appella E., and Anderson C.W. Post-translational modifications and activation of p53 by genotoxic stresses. Eur. J. Biochem. 268 (2001) 2764-2772
    • (2001) Eur. J. Biochem. , vol.268 , pp. 2764-2772
    • Appella, E.1    Anderson, C.W.2
  • 41
    • 4143050290 scopus 로고    scopus 로고
    • The interaction between FOXO and SIRT1: tipping the balance towards survival
    • Giannakou M.E., and Partridge L. The interaction between FOXO and SIRT1: tipping the balance towards survival. Trends Cell Biol. 14 (2004) 408-412
    • (2004) Trends Cell Biol. , vol.14 , pp. 408-412
    • Giannakou, M.E.1    Partridge, L.2
  • 42
    • 33749188883 scopus 로고    scopus 로고
    • FOXO4 transcriptional activity is regulated by monoubiquitination and USP7/HAUSP
    • van der Horst A., et al. FOXO4 transcriptional activity is regulated by monoubiquitination and USP7/HAUSP. Nat. Cell Biol. 8 (2006) 1064-1073
    • (2006) Nat. Cell Biol. , vol.8 , pp. 1064-1073
    • van der Horst, A.1
  • 43
    • 49849100725 scopus 로고    scopus 로고
    • Mdm2 induces mono-ubiquitination of FOXO4
    • Brenkman A.B., et al. Mdm2 induces mono-ubiquitination of FOXO4. PLoS One 3 (2008) e2819
    • (2008) PLoS One , vol.3
    • Brenkman, A.B.1
  • 44
    • 54449088845 scopus 로고    scopus 로고
    • RNAi screening for kinases and phosphatases identifies FoxO regulators
    • Mattila J., et al. RNAi screening for kinases and phosphatases identifies FoxO regulators. Proc. Natl. Acad. Sci. U. S. A. 105 (2008) 14873-14878
    • (2008) Proc. Natl. Acad. Sci. U. S. A. , vol.105 , pp. 14873-14878
    • Mattila, J.1
  • 45
    • 65149083526 scopus 로고    scopus 로고
    • Initiation of transcription - promoters for RNA polymerase II have short sequence elements
    • Oxford University Press/Cell Press
    • Lewin B. Initiation of transcription - promoters for RNA polymerase II have short sequence elements. Genes VII (2000), Oxford University Press/Cell Press 634-637
    • (2000) Genes VII , pp. 634-637
    • Lewin, B.1
  • 46
    • 0003422388 scopus 로고    scopus 로고
    • Eukaryotic transcription activators and repressors
    • W.H. Freeman and Company
    • Lodish H., et al. Eukaryotic transcription activators and repressors. Molecular Cell Biology. 4th edn (2000), W.H. Freeman and Company
    • (2000) Molecular Cell Biology. 4th edn
    • Lodish, H.1
  • 47
    • 47749149232 scopus 로고    scopus 로고
    • O-GlcNAc regulates FoxO activation in response to glucose
    • Housley M.P., et al. O-GlcNAc regulates FoxO activation in response to glucose. J. Biol. Chem. 283 (2008) 16283-16292
    • (2008) J. Biol. Chem. , vol.283 , pp. 16283-16292
    • Housley, M.P.1
  • 48
    • 0342614209 scopus 로고    scopus 로고
    • Unified nomenclature for the winged helix/forkhead transcription factors
    • Kaestner K.H., et al. Unified nomenclature for the winged helix/forkhead transcription factors. Genes Dev. 14 (2000) 142-146
    • (2000) Genes Dev. , vol.14 , pp. 142-146
    • Kaestner, K.H.1
  • 49
    • 0036387193 scopus 로고    scopus 로고
    • Forkhead transcription factors: key players in development and metabolism
    • Carlsson P., and Mahlapuu M. Forkhead transcription factors: key players in development and metabolism. Dev. Biol. 250 (2002) 1-23
    • (2002) Dev. Biol. , vol.250 , pp. 1-23
    • Carlsson, P.1    Mahlapuu, M.2
  • 50
    • 35548930209 scopus 로고    scopus 로고
    • The emerging roles of forkhead box (Fox) proteins in cancer
    • Myatt S.S., and Lam E.W. The emerging roles of forkhead box (Fox) proteins in cancer. Nat. Rev. Cancer 7 (2007) 847-859
    • (2007) Nat. Rev. Cancer , vol.7 , pp. 847-859
    • Myatt, S.S.1    Lam, E.W.2
  • 51
    • 0037866671 scopus 로고    scopus 로고
    • Fox's in development and disease
    • Lehmann O.J., et al. Fox's in development and disease. Trends Genet. 19 (2003) 339-344
    • (2003) Trends Genet. , vol.19 , pp. 339-344
    • Lehmann, O.J.1
  • 52
    • 0035131812 scopus 로고    scopus 로고
    • The putative forkhead transcription factor FOXL2 is mutated in blepharophimosis/ptosis/epicanthus inversus syndrome
    • Crisponi L., et al. The putative forkhead transcription factor FOXL2 is mutated in blepharophimosis/ptosis/epicanthus inversus syndrome. Nat. Genet. 27 (2001) 159-166
    • (2001) Nat. Genet. , vol.27 , pp. 159-166
    • Crisponi, L.1
  • 53
    • 1342327343 scopus 로고    scopus 로고
    • The murine winged-helix transcription factor Foxl2 is required for granulosa cell differentiation and ovary maintenance
    • Schmidt D., et al. The murine winged-helix transcription factor Foxl2 is required for granulosa cell differentiation and ovary maintenance. Development 131 (2004) 933-942
    • (2004) Development , vol.131 , pp. 933-942
    • Schmidt, D.1
  • 54
    • 34249888736 scopus 로고    scopus 로고
    • PHA-4/Foxa mediates diet-restriction-induced longevity of C. elegans
    • Panowski S.H., et al. PHA-4/Foxa mediates diet-restriction-induced longevity of C. elegans. Nature 447 (2007) 550-555
    • (2007) Nature , vol.447 , pp. 550-555
    • Panowski, S.H.1
  • 55
    • 0037325058 scopus 로고    scopus 로고
    • A sigmoidal transcriptional response: cooperativity, synergy and dosage effects
    • Veitia R.A. A sigmoidal transcriptional response: cooperativity, synergy and dosage effects. Biol. Rev. Camb. Philos. Soc. 78 (2003) 149-170
    • (2003) Biol. Rev. Camb. Philos. Soc. , vol.78 , pp. 149-170
    • Veitia, R.A.1


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