Hyperglycemia-enhanced ischemic brain damage in mutant manganese SOD mice is associated with suppression of HIF-1α

Neuroscience Letters

Volumn 456, Issue 2, 2009, Pages 89-92

  Bullock, Jeffery J ^a   Mehta, Suresh L ^a   Lin, Yanling ^b   Lolla, Padmavathi ^a   Li, P Andy ^a  

^a NORTH CAROLINA CENTRAL UNIVERSITY   (United States)

^b UNIVERSITY OF HAWAII   (United States)

Author keywords

Cerebral ischemia; Free radicals; Hyperglycemia; Hypoxia inducible factor; Manganese superoxide dismutase

Indexed keywords

HYPOXIA INDUCIBLE FACTOR 1ALPHA; MANGANESE SUPEROXIDE DISMUTASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN DAMAGE; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; CONTROLLED STUDY; ENZYME ACTIVITY; HYPERGLYCEMIA; IMMUNOHISTOCHEMISTRY; MIDDLE CEREBRAL ARTERY OCCLUSION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REPERFUSION; STROKE; WESTERN BLOTTING; WILD TYPE;

ANIMALS; BLOTTING, WESTERN; BRAIN ISCHEMIA; HYPERGLYCEMIA; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; IMMUNOHISTOCHEMISTRY; MICE; MICE, KNOCKOUT; MUTATION; SUPEROXIDE DISMUTASE;

EID: 64749112957     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2009.03.076     Document Type: Article

References (35)

1. Agani F.H., Pichiule P., Carlos Chavez J., and LaManna J.C. Inhibitors of mitochondrial complex I attenuate the accumulation of hypoxia-inducible factor-1 during hypoxia in Hep3B cells. Comp. Biochem. Physiol. A: Mol. Integr. Physiol. 132 (2002) 107-109
2. Allen K.L., Almeida A., Bates T.E., and Clark J.B. Changes of respiratory chain activity in mitochondrial and synaptosomal fractions isolated from the gerbil brain after graded ischaemia. J. Neurochem. 64 (1995) 2222-2229
3. Aminova L.R., Chavez J.C., Lee J., Ryu H., Kung A., Lamanna J.C., and Ratan R.R. Prosurvival and prodeath effects of hypoxia-inducible factor-1alpha stabilization in a murine hippocampal cell line. J. Biol. Chem. 280 (2005) 3996-4003
4. Baranova O., Miranda L.F., Pichiule P., Dragatsis I., Johnson R.S., and Chavez J.C. Neuron-specific inactivation of the hypoxia inducible factor 1 alpha increases brain injury in a mouse model of transient focal cerebral ischemia. J. Neurosci. 27 (2007) 6320-6332
5. Bergeron M., Yu A.Y., Solway K.E., Semenza G.L., and Sharp F.R. Induction of hypoxia-inducible factor-1 (HIF-1) and its target genes following focal ischaemia in rat brain. Eur. J. Neurosci. 11 (1999) 4159-4170
6. Chan P. Reactive oxygen radicals in signaling and damage in the ischemic brain. J. Cereb. Blood Flow Metab. 21 (2001) 2-14
7. Chavez A., Miranda L.F., Pichiule P., and Chavez J.C. Mitochondria and hypoxia-induced gene expression mediated by hypoxia-inducible factors. Ann. NY Acad. Sci. 1147 (2008) 312-320
8. Chavez J.C., Agani F., Pichiule P., and LaManna J.C. Expression of hypoxia-inducible factor-1alpha in the brain of rats during chronic hypoxia. J. Appl. Physiol. 89 (2000) 1937-1942
9. Chavez J.C., and LaManna J.C. Activation of hypoxia-inducible factor-1 in the rat cerebral cortex after transient global ischemia: potential role of insulin-like growth factor-1. J. Neurosci. 22 (2002) 8922-8931
10. Chen C., Hu Q., Yan J., Yang X., Shi X., Lei J., Chen L., Huang H., Han J., Zhang J.H., and Zhou C. Early inhibition of HIF-1alpha with small interfering RNA reduces ischemic-reperfused brain injury in rats. Neurobiol. Dis. 33 (2009) 509-517
11. Ding C., He Q., and Li P.A. Diabetes increases expression of ICAM after a brief period of cerebral ischemia. J. Neuroimmunol. 161 (2005) 61-67
12. Fujimura M., Morita-Fujimura Y., Noshita N., Sugawara T., Kawase M., and Chan P.H. The cytosolic antioxidant copper/zinc-superoxide dismutase prevents the early release of mitochondrial cytochrome c in ischemic brain after transient focal cerebral ischemia in mice. J. Neurosci. 20 (2000) 2817-2824
13. Goda N., Ryan H.E., Khadivi B., McNulty W., Rickert R.C., and Johnson R.S. Hypoxia-inducible factor 1alpha is essential for cell cycle arrest during hypoxia. Mol. Cell. Biol. 23 (2003) 359-369
14. Halterman M.W., and Federoff H.J. HIF-1alpha and p53 promote hypoxia-induced delayed neuronal death in models of CNS ischemia. Exp. Neurol. 159 (1999) 65-72
15. He Q., Csiszar K., and Li P. Transient forebrain ischemia induced phosphorylation of cAMP-responsive element-binding protein is suppressed by hyperglycemia. Neurobiol. Dis. 12 (2003) 25-34
16. Helton R., Cui J., Scheel J.R., Ellison J.A., Ames C., Gibson C., Blouw B., Ouyang L., Dragatsis I., Zeitlin S., Johnson R.S., Lipton S.A., and Barlow C. Brain-specific knock-out of hypoxia-inducible factor-1alpha reduces rather than increases hypoxic-ischemic damage. J. Neurosci. 25 (2005) 4099-4107
17. Janssens D., Delaive E., Remacle J., and Michiels C. Protection by bilobalide of the ischaemia-induced alterations of the mitochondrial respiratory activity. Fundam. Clin. Pharmacol. 14 (2000) 193-201
18. Jin K.L., Mao X.O., Nagayama T., Goldsmith P.C., and Greenberg D.A. Induction of vascular endothelial growth factor and hypoxia-inducible factor-1alpha by global ischemia in rat brain. Neuroscience 99 (2000) 577-585
19. Kamada H., Yu F., Nito C., and Chan P.H. Influence of hyperglycemia on oxidative stress and matrix metalloproteinase-9 activation after focal cerebral ischemia/reperfusion in rats: relation to blood-brain barrier dysfunction. Stroke 38 (2007) 1044-1049
20. Kim G.W., and Chan P.H. Involvement of superoxide in excitotoxicity and DNA fragmentation in striatal vulnerability in mice after treatment with the mitochondrial toxin, 3-nitropropionic acid. J. Cereb. Blood Flow Metab. 22 (2002) 798-809
21. Kohl R., Zhou J., and Brune B. Reactive oxygen species attenuate nitric-oxide-mediated hypoxia-inducible factor-1alpha stabilization. Free Radic. Biol. Med. 40 (2006) 1430-1442
22. Kondo T., Reaume A.G., Huang T.T., Carlson E., Murakami K., Chen S.F., Hoffman E.K., Scott R.W., Epstein C.J., and Chan P.H. Reduction of CuZn-superoxide dismutase activity exacerbates neuronal cell injury and edema formation after transient focal cerebral ischemia. J. Neurosci. 17 (1997) 4180-4189
23. Li P.A., Rasquinha I., He Q.P., Siesjo B.K., Csiszar K., Boyd C.D., and MacManus J.P. Hyperglycemia enhances DNA fragmentation after transient cerebral ischemia. J. Cereb. Blood Flow Metab. 21 (2001) 568-576
24. Li Y.X., Ding S.J., Xiao L., Guo W., and Zhan Q. Desferoxamine preconditioning protects against cerebral ischemia in rats by inducing expressions of hypoxia inducible factor 1 alpha and erythropoietin. Neurosci. Bull. 24 (2008) 89-95
25. Matsuzaki H., Tamatani M., Yamaguchi A., Namikawa K., Kiyama H., Vitek M.P., Mitsuda N., and Tohyama M. Vascular endothelial growth factor rescues hippocampal neurons from glutamate-induced toxicity: signal transduction cascades. FASEB J. 15 (2001) 1218-1220
26. Murakami K.T., Kawase M., Li Y., Sato S., Chen S.F., and Chan P.H. Mitchondrial susceptibility to oxidative stress exacerbates cerebral infarction that follows permanent focal cerebral ischemia in mutant mice with manganese superoxide dismutase deficiency. J. Neurosci. 18 (1998) 205-213
27. Muranyi M., Ding C., He Q., Lin Y., and Li P.A. Streptozotocin-induced diabetes causes astrocyte death after ischemia and reperfusion injury. Diabetes 55 (2006) 349-355
28. Muranyi M., Fujioka M., He Q., Han A., Yong G., Csiszar K., and Li P.A. Diabetes activates cell death pathway after transient focal cerebral ischemia. Diabetes 52 (2003) 481-486
29. Noshita N., Sugawara T., Fujimura M., Morita-Fujimura Y., and Chan P.H. Manganese superoxide dismutase affects cytochrome c release and caspase-9 activation after transient focal cerebral ischemia in mice. J. Cereb. Blood Flow Metab. 21 (2001) 557-567
30. Pichiule P., Chavez J.C., Schmidt A.M., and Vannucci S.J. Hypoxia-inducible factor-1 mediates neuronal expression of the receptor for advanced glycation end products following hypoxia/ischemia. J. Biol. Chem. 282 (2007) 36330-36340
31. Saito A., Kamii H., Kato I., Takasawa S., Kondo T., Chan P.H., Okamoto H., and Yoshimoto T. Transgenic CuZn-superoxide dismutase inhibits NO synthase induction in experimental subarachnoid hemorrhage. Stroke 32 (2001) 1652-1657
32. Thomas D.D., Ridnour L.A., Espey M.G., Donzelli S., Ambs S., Hussain S.P., Harris C.C., DeGraff W., Roberts D.D., Mitchell J.B., and Wink D.A. Superoxide fluxes limit nitric oxide-induced signaling. J. Biol. Chem. 281 (2006) 25984-25993
33. Wagner K.R., Kleinholz M., and Myers R.E. Delayed decreases in specific brain mitochondrial electron transfer complex activities and cytochrome concentrations following anoxia/ischemia. J. Neurol. Sci. 100 (1990) 142-151
34. Wenger R.H. Mammalian oxygen sensing, signalling and gene regulation. J. Exp. Biol. 203 (2000) 1253-1263
35. Xu J., Ji L.D., and Xu L.H. Endoplasmic reticulum may not be involved in the lead-induced apoptosis in PC 12 cells in vitro. Environ. Toxicol. (2009) Jan. 22, epub ahead of print