Comparative effects of glibenclamide, tedisamil, dofetilide, E-4031, and BRL-32872 on protein kinase A-activated chloride current in guinea pig ventricular myocytes

Journal of Cardiovascular Pharmacology

Volumn 31, Issue 4, 1998, Pages 551-557

  Faivre, Jean François ^a   Rouanet, Sabine ^a   Bril, Antoine ^a  

^a SmithKline Beecham Laboratoires P   (France)

Author keywords

BRL 32872; Dofetilide; E 4031; Glibenclamide; PKA activated chloride current; Tedisamil

Indexed keywords

1 [2 (6 METHYL 2 PYRIDYL)ETHYL] 4 (4 METHYLSULFONYLAMINOBENZOYL)PIPERIDINE; 4 ACETAMIDO 4' ISOTHIOCYANATOSTILBENE 2,2' DISULFONIC ACID; ACETYLCHOLINE; ADENOSINE TRIPHOSPHATE; ANTIARRHYTHMIC AGENT; CHLORIDE ION; CYCLIC AMP DEPENDENT PROTEIN KINASE; DOFETILIDE; GLIBENCLAMIDE; ISOPRENALINE; N (3,4 DIMETHOXYPHENYL) N [3 [[2 (3,4 DIMETHOXYPHENYL)ETHYL]PROPYL] 4 NITROBENZAMIDE]; POTASSIUM ION; PROPRANOLOL; TEDISAMIL; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CHLORIDE CURRENT; CONCENTRATION RESPONSE; CONTROLLED STUDY; GUINEA PIG; HEART MUSCLE CELL; HEART MUSCLE POTENTIAL; HEART VENTRICLE; MALE; NONHUMAN; PATCH CLAMP; POTASSIUM CURRENT; PRIORITY JOURNAL;

4-ACETAMIDO-4'-ISOTHIOCYANATOSTILBENE-2,2'-DISULFONIC ACID; ACETYLCHOLINE; ANIMALS; ANTI-ARRHYTHMIA AGENTS; BENZAMIDES; BICYCLO COMPOUNDS, HETEROCYCLIC; CARDIOTONIC AGENTS; CHLORIDES; CYCLIC AMP-DEPENDENT PROTEIN KINASES; CYCLOPROPANES; GLYBURIDE; GUINEA PIGS; HEART VENTRICLES; HYPOGLYCEMIC AGENTS; ION TRANSPORT; ISOPROTERENOL; MALE; MYOCARDIUM; PATCH-CLAMP TECHNIQUES; PHENETHYLAMINES; PIPERIDINES; POTASSIUM CHANNELS; PROPRANOLOL; PYRIDINES; SULFONAMIDES;

EID: 0031965742     PISSN: 01602446     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005344-199804000-00013     Document Type: Article

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