Oligomeric proanthocyanidins from grape seeds effectively inhibit ultraviolet-induced melanogenesis of human melanocytes in vitro

International Journal of Molecular Medicine

Volumn 23, Issue 2, 2009, Pages 197-204

  Zi, Shao Xia ^a,b   Ma, Hui Jun ^b   Li, You ^b   Liu, Wen ^b   Yang, Qing Qi ^b   Zhao, Guang ^b   Lian, Shi ^a  

^a CAPITAL MEDICAL UNIVERSITY   (China)

^b CHINESE PLA GENERAL HOSPITAL   (China)

Author keywords

Cell cycle; Melanocytes; Melanogenesis; Photo protection; Proanthocyanidins; Reactive oxidative species; UV light

Indexed keywords

ASCORBIC ACID; GRAPE SEED EXTRACT; MELANIN; MONOPHENOL MONOOXYGENASE; PROANTHOCYANIDIN DERIVATIVE; REACTIVE OXYGEN METABOLITE; TYROSINASE RELATED PROTEIN 1; TYROSINASE RELATED PROTEIN 2; DOPACHROME ISOMERASE; ISOMERASE; OXIDOREDUCTASE; PROANTHOCYANIDIN; TYROSINASE RELATED PROTEIN; TYROSINASE-RELATED PROTEIN;

ANTIOXIDANT ACTIVITY; ARTICLE; CELL CULTURE; CELL CYCLE; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CELL LEVEL; CELL PROTECTION; CELL VIABILITY; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; ENZYME INHIBITION; GRAPE; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; IN VITRO STUDY; MELANOCYTE; MELANOGENESIS; PHARMACOLOGICAL BLOCKING; PLANT SEED; PRIORITY JOURNAL; RADIATION PROTECTION; ULTRAVIOLET RADIATION; BIOSYNTHESIS; CELL SURVIVAL; CHEMISTRY; CYTOLOGY; DRUG EFFECT; GENETICS; METABOLISM; RADIATION EXPOSURE; SKIN; SKIN PIGMENTATION;

CELL CYCLE; CELL SURVIVAL; HUMANS; INTRAMOLECULAR OXIDOREDUCTASES; MELANINS; MELANOCYTES; OXIDOREDUCTASES; PROANTHOCYANIDINS; REACTIVE OXYGEN SPECIES; SEEDS; SKIN; SKIN PIGMENTATION; ULTRAVIOLET RAYS; VITIS;

EID: 64749100097     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm_00000117     Document Type: Article

References (41)

1. Friedmann PS and Gilchrest BA: Ultraviolet radiation directly induces pigment production by cultured human melanocytes. J Cell Physiol 133: 88-94, 1987.
2. Libow LF, Scheide S and Deleo VA: Ultraviolet radiation acts as an independent mitogen for normal human melanocytes in culture. Pigment Cell Res 1: 397-401, 1988.
3. Gilchrest BA, Park H-Y, Eller MS and Yaar M: Mechanisms of ultraviolet light-induced pigmentation. Photochem Photobiol 63: 1-10, 1996.
4. Tomita Y, Hariu A, Kato C and Seiji M: Radical production during tyrosinase reaction, dopa-melanin formation, and photoirradiation of dopa-melanin. J Invest Dermatol 82: 573-576, 1984.
5. Peak JG and Peak MJ: Comparison of initial yields of DNA-to-protein crosslinks and single-strand breaks induced in cultured human cells by far and near-ultraviolet light, blue light and X-rays. Mutat Res 246: 187-191, 1991.
6. Wenczl E, Van der Schans GP, Roza L, Kolb RM, Timmerman AJ, Smit NPM, Pavel S and Schothorst AA: (Pheo)Melanin photo-sensitizes UVA-induced DNA damage in cultured human melanocytes. J Invest Dermatol 111: 678-682, 1998.
7. Karg E, Odh G, Wittbjer A, Rosengren E and Rorsman H: Hydrogen peroxide as an inducer of elevated tyrosinase level in melanoma cells. J Invest Dermatol 100: S209-S213, 1993.
8. Quevedo WC Jr, Holstein TJ, Dyckman J, Mcdonald CJ and Isaacson EL: Inhibition of UVR-induced tanning and immunosuppression by topical applications of vitamin C and E to the skin of hairless (hr/hr) mice. Pigment Cell Res 13: 89-98, 2000.
9. 2. Carcinogenesis 13: 2003-2007, 1992.
10. Lee JH, An T, Chung JH, Kim KH, Eun HC and Cho KH: Acute effects of UVB radiation on the proliferation and differentiation of keratinocytes. Photodermatol Photoimmunol Photomed 18: 253-261, 2002.
11. Porter LJ: Flavans and proanthocyanidins. In: The Flavonoids - Advances in Research since 1986. Harborne JB (ed). Chapman and Hall, London, pp23-55, 1986.
12. Carando S and Teissedre P-L: Catechin and procyanidin levels in French wines: contribution to dietary intake. In: Plant Polyphenols 2: Chemistry, Biology, Pharmacology, Ecology. Gross GG, Hemingway RW and Yoshida T (eds). Kluwer Academic/Plenum Publishers, New York, pp725-737, 1999.
13. Waterhouse AL and Walzem RL: Nutrition of grape phenolics. In: Flavonoids in Health and Disease. Rice-Evans CA and Packer L (eds). Marcel Dekkar, New York, pp359-385, 1998.
14. Monagas M, Gómez-Cordovés C, Bartolomé B, Laureano O and Ricardo da Silva JM: Monomeric, oligomeric, and polymeric flavan-3-ol composition of wines and grapes from Vitis vinifera L. Cv. Graciano, Tempranillo, and Cabernet Sauvignon. J Agric Food Chem. 51: 6475-6481, 2003.
15. Lau DW and King AJ: Pre- and post-mortem use of grape seed extract in dark poultry meat to inhibit development of thiobarbituric acid reactive substances. J Agric Food Chem 51: 1602-1607, 2003.
16. Yamakoshi J, Saito M, Kataoka S and Tokutake S: Procyanidin-rich extract from grape seeds prevents cataract formation in hereditary cataractous (ICR/f) rats. J Agric Food Chem 50: 4983-4988, 2002.
17. Roychowdhury S, Wolf G, Keilhoff G, Bagchi D and Horn T: Protection of primary glial cells by grape seed proanthocyanidin extract against nitrosative/oxidative stress. Nitric Oxide 5: 137-149, 2001.
18. Koga T, Moro K, Nakamori K, Yamakoshi J, Hosoyama H, Kataoka S and Ariga T: Increase of antioxidative potential of rat plasma by oral administration of proanthocyanidin-rich extract from grape seeds. J Agric Food Chem 47: 1892-1897, 1999.
19. Bouhamidi R, Prevost V and Nouvelot A: High protection by grape seed proanthocyanidins (GSPC) of polyunsaturated fatty acids against UV-C induced peroxidation. C R Acad Sci III 321: 31-38, 1998.
20. Seo SY, Sharma VK and Sharma N: Mushroom tyrosinase: recent prospects. J Agric Food Chem 51: 2837-2853, 2003.
21. Bagchi D, Bagchi M, Stohs SJ, Das DK, Ray SD, Kuszynski CA, Joshi SS and Pruess HG: Free radicals and grape seed proanthocyanidin extract: importance in human health and disease prevention. Toxicology 148: 187-197, 2000.
22. Shoji T, Masumoto S, Moriichi N, et al: Procyanidin trimers to pentamers fractionated from apple inhibit melanogenesis in B16 mouse melanoma cells. J Agric Food Chem 53: 6105-6111, 2005.
23. Yamakoshi J, Otsuka F, Sano A, Tokutake S, Saito M, Kikuchi M and Kubota Y: Lightening effect on ultraviolet-induced pigmentation of guinea pig skin by oral administration of a proanthocyanidin-rich extract from grape seeds. Pigment Cell Res 16: 629-638, 2003.
24. Abdel-Malek Z, Swope V, Smalara D, Babcock G, Dawes S and Nordlund J: Analysis of the UV-induced melanogenesis and growth arrest of human melanocytes. Pigment Cell Res 7: 326-332, 1994.
25. Ando H, Funasaka Y, Oka M, Ohashi A, Furumura M, Matsunaga J, Matsunaga N, Hearing VJ and Ichihashi M: Possible involvement of proteolytic degradation of tyrosinase in the regulatory effect of fatty acids on melanogenesis. J Lipid Res 40: 1312-1316, 1999.
26. Lv N, Koo JH, Yoon HY, Yu J, Kim KA, Choi IW, Kwon KB, Kwon KS, Kim HU, Park JW and Park BH: Effect of Angelica gigas extract on melanogenesis in B16 melanoma cells. Int J Mol Med 20: 763-767, 2007.
27. Szejda P, Parce JW, Seeds MS and Bass DA: Flow cytometric quantitation of oxidative product formation by polymorphonuclear leukocytes during phagocytosis. J Immunol 133: 3303-3307, 1984.
28. Xiao L, Matsubayashi K and Miwa N: Inhibitory effect of the water-soluble polymer-wrapped derivative of fullerene on UVA-induced melanogenesis via downregulation of tyrosinase expression in human melanocytes and skin tissues. Arch Dermatol Res 299: 245-257, 2007.
29. Yamaguchi F, Yoshimura Y, Nakazawa H and Ariga T: Free radical scavenging activity of grape seed extract and antioxidants by electron spin resonance spectrometry in an H2O2/NaOH/DMSO system. J Agric Food Chem 47: 2544-2548, 1999.
30. Bagchi D, Garg A, Krohn RL, Bagchi M, Bagchi DJ, Balmoori J and Stohs SJ: Protective effects of grape seed proanthocyanidins and selected antioxidants against TPA-induced hepatic and brain lipid peroxidation and DNA fragmentation, and peritoneal macrophage activation in mice. Gen Pharmac 30: 771-776, 1998.
31. Hearing VJ and Tsukamoto K: Enzymatic control of pigmentation in mammals. FASEB J 5: 2902-2909, 1991.
32. Romero-Graillet C, Aberdam E, Biagoli N, Massabni W, Ortonne JP and Ballotti R: Ultraviolet B radiation acts through the nitric oxide and cGMP signal transduction pathway to stimulate melanogenesis in human melanocytes. J Biol Chem 271: 28052-28056, 1996.
33. Romero-Graillet C, Aberdam E, Clement M, Ortonne JP and Ballotti R: Nitric oxide produced by ultraviolet-irradiated keratinocytes stimulates melanogenesis. J Clin Invest 99: 635-642, 1997.
34. Sasaki M, Horikoshi T, Uchiwa H and Miyachi Y: Up-regulation of tyrosinase gene by nitric oxide in human melanocytes. Pigment Cell Res 13: 248-252, 2000.
35. Halliwell B: Antioxidant defence mechanisms: from the beginning to the end (of the beginning). Free Radic Res 31: 261-272, 1999.
36. Courdavault S, Baudouin C, Charveron M, Favier A, Cadet J and Douki T: Larger yield of cyclobutane dimers than 8-oxo-7, 8-dihydroguanine in the DNA of UVA-irradiated human skin cells. Mutat Res 556: 135-142, 2004.
37. Barzilai A and Yamamoto K-I: DNA damage responses to oxidative stress. DNA Repair 3: 1109-1115, 2004.
38. Beer JZ, Olvey KM, Miller SA, Thomas DP and Godar DE: Non-nuclear damage and cell lysis are induced by UVA, but not UVB or UVC radiation in three strains of L5178Y cells. Photochem Photobiol 58: 676-681, 1993.
39. Tobi SE, Paul N and McMillan TJ: Glutathione modulates the level of free radicals produced in UVA-irradiated cells. J Photochem Photobiol B 57: 102-112, 2000.
40. Kaufmann WK and Wilson SJ: G1 arrest and cell-cycle-dependent clastogenesis in UV-irradiated human fibroblasts. Mutat Res 314: 67-76, 1994.
41. Kowalczuk CI, Priestner MC, Pearson AJ, Saunders RD and Bouffler SD: Wavelength dependence of cellular responses in human melanocytes and melanoma cells following exposure to ultraviolet radiation. Int J Radiat Biol 82: 781-792, 2006.