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Volumn 214, Issue 6, 2009, Pages 454-466

Dynamics of gut mucosal and systemic Th1/Th2 cytokine responses in interferon-gamma and interleukin-12p40 knock out mice during primary and challenge Cryptosporidium parvum infection

Author keywords

Cryptosporidium parvum; Cytokine; Infection; Interleukin; Mouse; Th1 response; Th2 response

Indexed keywords

CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 12P40; INTERLEUKIN 13; INTERLEUKIN 18; INTERLEUKIN 18 ANTIBODY; INTERLEUKIN 4; MESSENGER RNA; TUMOR NECROSIS FACTOR ALPHA;

EID: 64649087038     PISSN: 01712985     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.imbio.2008.11.015     Document Type: Article
Times cited : (54)

References (53)
  • 1
    • 0028118364 scopus 로고
    • Susceptibility of major histocompatibility complex (MHC) class I- and MHC class II-deficient mice to Cryptosporidium parvum infection
    • Aguirre S.A., Mason P.H., and Perryman L.E. Susceptibility of major histocompatibility complex (MHC) class I- and MHC class II-deficient mice to Cryptosporidium parvum infection. Infect. Immun. 62 (1994) 697-699
    • (1994) Infect. Immun. , vol.62 , pp. 697-699
    • Aguirre, S.A.1    Mason, P.H.2    Perryman, L.E.3
  • 3
    • 0032554784 scopus 로고    scopus 로고
    • Differences between IL-4R alpha-deficient and IL-4-deficient mice reveal a role for IL-13 in the regulation of Th2 responses
    • Barner M., Mohrs M., Brombacher F., and Kopf M. Differences between IL-4R alpha-deficient and IL-4-deficient mice reveal a role for IL-13 in the regulation of Th2 responses. Curr. Biol. 8 (1998) 669-672
    • (1998) Curr. Biol. , vol.8 , pp. 669-672
    • Barner, M.1    Mohrs, M.2    Brombacher, F.3    Kopf, M.4
  • 4
    • 0026500979 scopus 로고
    • IL-4 induces a Th2 response in Leishmania major-infected mice
    • Chatelain R., Varkila K., and Coffman R.L. IL-4 induces a Th2 response in Leishmania major-infected mice. J. Immunol. 148 (1992) 1182-1187
    • (1992) J. Immunol. , vol.148 , pp. 1182-1187
    • Chatelain, R.1    Varkila, K.2    Coffman, R.L.3
  • 5
    • 0027250396 scopus 로고
    • Requirements for CD4+ cells and gamma interferon in resolution of established Cryptosporidium parvum infection in mice
    • Chen W., Harp J.A., and Harmsen A.G. Requirements for CD4+ cells and gamma interferon in resolution of established Cryptosporidium parvum infection in mice. Infect. Immun. 61 (1993) 3928-3932
    • (1993) Infect. Immun. , vol.61 , pp. 3928-3932
    • Chen, W.1    Harp, J.A.2    Harmsen, A.G.3
  • 6
    • 0027160659 scopus 로고
    • Gamma interferon functions in resistance to Cryptosporidium parvum infection in severe combined immunodeficient mice
    • Chen W., Harp J.A., Harmsen A.G., and Havell E.A. Gamma interferon functions in resistance to Cryptosporidium parvum infection in severe combined immunodeficient mice. Infect. Immun. 61 (1993) 3548-3551
    • (1993) Infect. Immun. , vol.61 , pp. 3548-3551
    • Chen, W.1    Harp, J.A.2    Harmsen, A.G.3    Havell, E.A.4
  • 7
    • 0032442862 scopus 로고    scopus 로고
    • Interleukin-4 and interleukin-13: their similarities and discrepancies
    • Chomarat P., and Banchereau J. Interleukin-4 and interleukin-13: their similarities and discrepancies. Int. Rev. Immunol. 17 (1998) 1-52
    • (1998) Int. Rev. Immunol. , vol.17 , pp. 1-52
    • Chomarat, P.1    Banchereau, J.2
  • 8
    • 0027400726 scopus 로고
    • Multiple defects of immune cell function in mice with disrupted interferon-gamma genes
    • Dalton D.K., Pitts-Meek S., Keshav S., Figari I.S., Bradley A., and Stewart T.A. Multiple defects of immune cell function in mice with disrupted interferon-gamma genes. Science 259 (1993) 1739-1742
    • (1993) Science , vol.259 , pp. 1739-1742
    • Dalton, D.K.1    Pitts-Meek, S.2    Keshav, S.3    Figari, I.S.4    Bradley, A.5    Stewart, T.A.6
  • 9
    • 0032607876 scopus 로고    scopus 로고
    • IL-18: A TH1-inducing, proinflammatory cytokine and new member of the IL-1 family
    • Dinarello C.A. IL-18: A TH1-inducing, proinflammatory cytokine and new member of the IL-1 family. J. Allergy Clin. Immunol. 103 (1999) 11-24
    • (1999) J. Allergy Clin. Immunol. , vol.103 , pp. 11-24
    • Dinarello, C.A.1
  • 11
    • 33751440000 scopus 로고    scopus 로고
    • Cryptosporidium parvum: the contribution of Th1-inducing pathways to the resolution of infection in mice
    • Ehigiator H.N., McNair N., and Mead J.R. Cryptosporidium parvum: the contribution of Th1-inducing pathways to the resolution of infection in mice. Exp. Parasitol. 115 (2007) 107-113
    • (2007) Exp. Parasitol. , vol.115 , pp. 107-113
    • Ehigiator, H.N.1    McNair, N.2    Mead, J.R.3
  • 12
    • 0027864929 scopus 로고
    • Role of CD4+ TH1- and TH2-cell-secreted cytokines in cryptosporidiosis
    • Enriquez F.J., and Sterling C.R. Role of CD4+ TH1- and TH2-cell-secreted cytokines in cryptosporidiosis. Folia Parasitol. Praha. 40 (1993) 307-311
    • (1993) Folia Parasitol. Praha. , vol.40 , pp. 307-311
    • Enriquez, F.J.1    Sterling, C.R.2
  • 13
    • 38449117444 scopus 로고    scopus 로고
    • Role of murine Peyer's patch lymphocytes against primary and challenge infections with Cryptosporidium parvum
    • Guk S.M., and Chai J.Y. Role of murine Peyer's patch lymphocytes against primary and challenge infections with Cryptosporidium parvum. Korean J. Parasitol. 45 (2007) 175-180
    • (2007) Korean J. Parasitol. , vol.45 , pp. 175-180
    • Guk, S.M.1    Chai, J.Y.2
  • 14
    • 0242684749 scopus 로고    scopus 로고
    • Role of murine intestinal intraepithelial lymphocytes and lamina propria lymphocytes against primary and challenge infections with Cryptosporidium parvum
    • Guk S.M., Yong T.S., and Chai J.Y. Role of murine intestinal intraepithelial lymphocytes and lamina propria lymphocytes against primary and challenge infections with Cryptosporidium parvum. J. Parasitol. 89 (2003) 270-275
    • (2003) J. Parasitol. , vol.89 , pp. 270-275
    • Guk, S.M.1    Yong, T.S.2    Chai, J.Y.3
  • 15
    • 0028117288 scopus 로고
    • In vitro proliferation and production of gamma interferon by murine CD4+ cells in response to Cryptosporidium parvum antigen
    • Harp J.A., Whitmire W.M., and Sacco R. In vitro proliferation and production of gamma interferon by murine CD4+ cells in response to Cryptosporidium parvum antigen. J. Parasitol. 80 (1994) 67-72
    • (1994) J. Parasitol. , vol.80 , pp. 67-72
    • Harp, J.A.1    Whitmire, W.M.2    Sacco, R.3
  • 16
    • 0033827625 scopus 로고    scopus 로고
    • Interferon-gamma is required for innate immunity to Cryptosporidium parvum in mice
    • Hayward A.R., Chmura K., and Cosyns M. Interferon-gamma is required for innate immunity to Cryptosporidium parvum in mice. J. Infect. Dis. 182 (2000) 1001-1004
    • (2000) J. Infect. Dis. , vol.182 , pp. 1001-1004
    • Hayward, A.R.1    Chmura, K.2    Cosyns, M.3
  • 17
    • 0035817397 scopus 로고    scopus 로고
    • Interleukin (IL)-18 promotes the development of chronic gastrointestinal helminth infection by downregulating IL-13
    • Helmby H., Takeda K., Akira S., and Grencis R.K. Interleukin (IL)-18 promotes the development of chronic gastrointestinal helminth infection by downregulating IL-13. J. Exp. Med. 194 (2001) 355-364
    • (2001) J. Exp. Med. , vol.194 , pp. 355-364
    • Helmby, H.1    Takeda, K.2    Akira, S.3    Grencis, R.K.4
  • 18
    • 0030296273 scopus 로고    scopus 로고
    • Alterations of the mucosal immune system due to Cryptosporidium parvum infection in normal mice
    • Huang D.S., Lopez M.C., Wang J.Y., Martinez F., and Watson R.R. Alterations of the mucosal immune system due to Cryptosporidium parvum infection in normal mice. Cell Immunol. 173 (1996) 176-182
    • (1996) Cell Immunol. , vol.173 , pp. 176-182
    • Huang, D.S.1    Lopez, M.C.2    Wang, J.Y.3    Martinez, F.4    Watson, R.R.5
  • 19
    • 0036604428 scopus 로고    scopus 로고
    • IL-18 contributes to host resistance against infection with Pseudomonas aeruginosa through induction of IFN-gamma production
    • Huang X., McClellan S.A., Barrett R.P., and Hazlett L.D. IL-18 contributes to host resistance against infection with Pseudomonas aeruginosa through induction of IFN-gamma production. J. Immunol. 168 (2002) 5756-5763
    • (2002) J. Immunol. , vol.168 , pp. 5756-5763
    • Huang, X.1    McClellan, S.A.2    Barrett, R.P.3    Hazlett, L.D.4
  • 20
    • 38649136275 scopus 로고    scopus 로고
    • Humoral immune response in interleukin-12 and interferon-g deficient mice after infection with Cryptosporidium parvum
    • Jakobi V., and Petry F. Humoral immune response in interleukin-12 and interferon-g deficient mice after infection with Cryptosporidium parvum. Parasite Immunol. 30 (2008) 151-161
    • (2008) Parasite Immunol. , vol.30 , pp. 151-161
    • Jakobi, V.1    Petry, F.2
  • 21
    • 0029842242 scopus 로고    scopus 로고
    • Kinetics of mucosal ileal gamma-interferon response during cryptosporidiosis in immunocompetent neonatal mice
    • Kapel N., Benhamou Y., Buraud M., Magne D., Opolon P., and Gobert J.G. Kinetics of mucosal ileal gamma-interferon response during cryptosporidiosis in immunocompetent neonatal mice. Parasitol. Res. 82 (1996) 664-667
    • (1996) Parasitol. Res. , vol.82 , pp. 664-667
    • Kapel, N.1    Benhamou, Y.2    Buraud, M.3    Magne, D.4    Opolon, P.5    Gobert, J.G.6
  • 22
    • 0034662234 scopus 로고    scopus 로고
    • IL-18 contributes to host resistance against infection with Cryptococcus neoformans in mice with defective IL-12 synthesis through induction of IFN-gamma production by NK cells
    • Kawakami K., Koguchi Y., Qureshi M.H., Miyazato A., Yara S., Kinjo Y., Iwakura Y., Takeda K., Akira S., Kurimoto M., and Saito A. IL-18 contributes to host resistance against infection with Cryptococcus neoformans in mice with defective IL-12 synthesis through induction of IFN-gamma production by NK cells. J. Immunol. 165 (2000) 941-947
    • (2000) J. Immunol. , vol.165 , pp. 941-947
    • Kawakami, K.1    Koguchi, Y.2    Qureshi, M.H.3    Miyazato, A.4    Yara, S.5    Kinjo, Y.6    Iwakura, Y.7    Takeda, K.8    Akira, S.9    Kurimoto, M.10    Saito, A.11
  • 24
    • 0035112043 scopus 로고    scopus 로고
    • Cryptosporidium parvum-specific mucosal immune response in C57BL/6 neonatal and gamma interferon-deficient mice: role of tumor necrosis factor alpha in protection
    • Lacroix S., Mancassola R., Naciri M., and Laurent F. Cryptosporidium parvum-specific mucosal immune response in C57BL/6 neonatal and gamma interferon-deficient mice: role of tumor necrosis factor alpha in protection. Infect. Immun. 69 (2001) 1635-1642
    • (2001) Infect. Immun. , vol.69 , pp. 1635-1642
    • Lacroix, S.1    Mancassola, R.2    Naciri, M.3    Laurent, F.4
  • 25
    • 28444459530 scopus 로고    scopus 로고
    • An early intestinal mucosal source of gamma interferon is associated with resistance to and control of Cryptosporidium parvum infection in mice
    • Leav B.A., Yoshida M., Rogers K., Cohen S., Godiwala N., Blumberg R.S., and Ward H. An early intestinal mucosal source of gamma interferon is associated with resistance to and control of Cryptosporidium parvum infection in mice. Infect. Immun. 73 (2005) 8425-8428
    • (2005) Infect. Immun. , vol.73 , pp. 8425-8428
    • Leav, B.A.1    Yoshida, M.2    Rogers, K.3    Cohen, S.4    Godiwala, N.5    Blumberg, R.S.6    Ward, H.7
  • 27
    • 0036132642 scopus 로고    scopus 로고
    • Generation of neutralizing mouse anti-mouse IL-18 antibodies for inhibition of inflammatory responses in vivo
    • Lochner M., Wagner H., Classen M., and Forster I. Generation of neutralizing mouse anti-mouse IL-18 antibodies for inhibition of inflammatory responses in vivo. J. Immunol. Methods 259 (2002) 149-157
    • (2002) J. Immunol. Methods , vol.259 , pp. 149-157
    • Lochner, M.1    Wagner, H.2    Classen, M.3    Forster, I.4
  • 29
    • 0027936641 scopus 로고
    • Mechanisms of innate and acquired resistance to Cryptosporidium parvum infection in SCID mice
    • McDonald V., and Bancroft G.J. Mechanisms of innate and acquired resistance to Cryptosporidium parvum infection in SCID mice. Parasite Immunol. 16 (1994) 315-320
    • (1994) Parasite Immunol. , vol.16 , pp. 315-320
    • McDonald, V.1    Bancroft, G.J.2
  • 30
    • 0026740708 scopus 로고
    • Immune responses to Cryptosporidium muris and Cryptosporidium parvum in adult immunocompetent or immunocompromised (nude and SCID) mice
    • McDonald V., Deer R., Uni S., Iseki M., and Bancroft G.J. Immune responses to Cryptosporidium muris and Cryptosporidium parvum in adult immunocompetent or immunocompromised (nude and SCID) mice. Infect. Immun. 60 (1992) 3325-3331
    • (1992) Infect. Immun. , vol.60 , pp. 3325-3331
    • McDonald, V.1    Deer, R.2    Uni, S.3    Iseki, M.4    Bancroft, G.J.5
  • 31
    • 4344575964 scopus 로고    scopus 로고
    • Protection against the early acute phase of Cryptosporidium parvum infection conferred by interleukin-4-induced expression of T helper 1 cytokines
    • McDonald S.A.C., O'Grady J.E., Bajaj-Elliott M., Notley C.A., Alexander J., Brombacher F., and McDonald V. Protection against the early acute phase of Cryptosporidium parvum infection conferred by interleukin-4-induced expression of T helper 1 cytokines. J. Infect. Dis. 190 (2004) 1019-1025
    • (2004) J. Infect. Dis. , vol.190 , pp. 1019-1025
    • McDonald, S.A.C.1    O'Grady, J.E.2    Bajaj-Elliott, M.3    Notley, C.A.4    Alexander, J.5    Brombacher, F.6    McDonald, V.7
  • 33
    • 0032510452 scopus 로고    scopus 로고
    • A distinct role for interleukin-13 in Th2-cell-mediated immune responses
    • McKenzie G.J., Bancroft A., Grencis R.K., and McKenzie A.N. A distinct role for interleukin-13 in Th2-cell-mediated immune responses. Curr. Biol. 8 (1998) 339-342
    • (1998) Curr. Biol. , vol.8 , pp. 339-342
    • McKenzie, G.J.1    Bancroft, A.2    Grencis, R.K.3    McKenzie, A.N.4
  • 34
    • 0031739386 scopus 로고    scopus 로고
    • Susceptibility differences to Cryptosporidium parvum infection in two strains of gamma interferon knockout mice
    • Mead J.R., and You X. Susceptibility differences to Cryptosporidium parvum infection in two strains of gamma interferon knockout mice. J. Parasitol. 84 (1998) 1045-1048
    • (1998) J. Parasitol. , vol.84 , pp. 1045-1048
    • Mead, J.R.1    You, X.2
  • 35
    • 0026251084 scopus 로고
    • Cryptosporidial infections in SCID mice reconstituted with human or murine lymphocytes
    • Mead J.R., Arrowood M.J., Healey M.C., and Sidwell R.W. Cryptosporidial infections in SCID mice reconstituted with human or murine lymphocytes. J. Protozool. 38 (1991) 59S-61S
    • (1991) J. Protozool. , vol.38
    • Mead, J.R.1    Arrowood, M.J.2    Healey, M.C.3    Sidwell, R.W.4
  • 38
    • 0033491194 scopus 로고    scopus 로고
    • Interleukin-18: a novel cytokine that augments both innate and acquired immunity
    • Okamura H., Tsutsui H., Kashiwamura S., Yoshimoto T., and Nakanishi K. Interleukin-18: a novel cytokine that augments both innate and acquired immunity. Adv. Immunol. 70 (1998) 281-312
    • (1998) Adv. Immunol. , vol.70 , pp. 281-312
    • Okamura, H.1    Tsutsui, H.2    Kashiwamura, S.3    Yoshimoto, T.4    Nakanishi, K.5
  • 40
    • 0028199776 scopus 로고
    • Effect of spleen cell populations on resolution of Cryptosporidium parvum infection in SCID mice
    • Perryman L.E., Mason P.H., and Chrisp C.E. Effect of spleen cell populations on resolution of Cryptosporidium parvum infection in SCID mice. Infect. Immun. 62 (1994) 1474-1477
    • (1994) Infect. Immun. , vol.62 , pp. 1474-1477
    • Perryman, L.E.1    Mason, P.H.2    Chrisp, C.E.3
  • 41
    • 0033990048 scopus 로고    scopus 로고
    • Primer3 on the WWW for general users and for biologist programmers
    • Krawetz S., and Misener S. (Eds), Humana Press, Totowa, NJ
    • Rozen S., and Skaletsky H. Primer3 on the WWW for general users and for biologist programmers. In: Krawetz S., and Misener S. (Eds). Bioinformatics Methods and Protocols: Methods in Molecular Biology (2000), Humana Press, Totowa, NJ 365-386
    • (2000) Bioinformatics Methods and Protocols: Methods in Molecular Biology , pp. 365-386
    • Rozen, S.1    Skaletsky, H.2
  • 42
    • 26944455613 scopus 로고    scopus 로고
    • Kinetics of Cryptosporidium parvum-specific cytokine responses in healing and nonhealing murine models of C. parvum infection
    • Singh I., Theodos C., Li W., and Tzipori S. Kinetics of Cryptosporidium parvum-specific cytokine responses in healing and nonhealing murine models of C. parvum infection. Parasitol. Res. 97 (2005) 309-317
    • (2005) Parasitol. Res. , vol.97 , pp. 309-317
    • Singh, I.1    Theodos, C.2    Li, W.3    Tzipori, S.4
  • 43
    • 0034127714 scopus 로고    scopus 로고
    • Cytokine expression and specific lymphocyte proliferation in two strains of Cryptosporidium parvum-infected gamma-interferon knockout mice
    • Smith L.M., Bonafonte M.T., and Mead J.R. Cytokine expression and specific lymphocyte proliferation in two strains of Cryptosporidium parvum-infected gamma-interferon knockout mice. J. Parasitol. 86 (2000) 300-307
    • (2000) J. Parasitol. , vol.86 , pp. 300-307
    • Smith, L.M.1    Bonafonte, M.T.2    Mead, J.R.3
  • 44
    • 0034841642 scopus 로고    scopus 로고
    • Exogenous interleukin-12 (IL-12) exacerbates Cryptosporidium parvum infection in gamma interferon knockout mice
    • Smith L.M., Bonafonte M.T., Campbell L.D., and Mead J.R. Exogenous interleukin-12 (IL-12) exacerbates Cryptosporidium parvum infection in gamma interferon knockout mice. Exp. Parasitol. 98 (2001) 123-133
    • (2001) Exp. Parasitol. , vol.98 , pp. 123-133
    • Smith, L.M.1    Bonafonte, M.T.2    Campbell, L.D.3    Mead, J.R.4
  • 45
    • 16244363083 scopus 로고    scopus 로고
    • Production of IL-27 and other IL-12 family cytokines by microglia and their subpopulations
    • Sonobe Y., Yawata I., Kawanokuchi J., Takeuchi H., Mizuno T., and Suzumura A. Production of IL-27 and other IL-12 family cytokines by microglia and their subpopulations. Brain Res. 1040 (2005) 202-207
    • (2005) Brain Res. , vol.1040 , pp. 202-207
    • Sonobe, Y.1    Yawata, I.2    Kawanokuchi, J.3    Takeuchi, H.4    Mizuno, T.5    Suzumura, A.6
  • 46
    • 0025875437 scopus 로고
    • Cryptosporidium infection in an adult mouse model. Independent roles for IFN-gamma and CD4+ T lymphocytes in protective immunity
    • Ungar B.L., Kao T.C., Burris J.A., and Finkelman F.D. Cryptosporidium infection in an adult mouse model. Independent roles for IFN-gamma and CD4+ T lymphocytes in protective immunity. J. Immunol. 147 (1991) 1014-1022
    • (1991) J. Immunol. , vol.147 , pp. 1014-1022
    • Ungar, B.L.1    Kao, T.C.2    Burris, J.A.3    Finkelman, F.D.4
  • 47
    • 0030063209 scopus 로고    scopus 로고
    • IL-12 protects immunocompetent and immunodeficient neonatal mice against infection with Cryptosporidium parvum
    • Urban Jr. J.F., Fayer R., Chen S.J., Gause W.C., Gately M.K., and Finkelman F.D. IL-12 protects immunocompetent and immunodeficient neonatal mice against infection with Cryptosporidium parvum. J. Immunol. 156 (1996) 263-268
    • (1996) J. Immunol. , vol.156 , pp. 263-268
    • Urban Jr., J.F.1    Fayer, R.2    Chen, S.J.3    Gause, W.C.4    Gately, M.K.5    Finkelman, F.D.6
  • 48
    • 0032007351 scopus 로고    scopus 로고
    • IL-13, IL-4Ralpha, and Stat6 are required for the expulsion of the gastrointestinal nematode parasite Nippostrongylus brasiliensis
    • Urban Jr. J.F., Noben-Trauth N., Donaldson D.D., Madden K.B., Morris S.C., Collins M., and Finkelman F.D. IL-13, IL-4Ralpha, and Stat6 are required for the expulsion of the gastrointestinal nematode parasite Nippostrongylus brasiliensis. Immunity 8 (1998) 255-264
    • (1998) Immunity , vol.8 , pp. 255-264
    • Urban Jr., J.F.1    Noben-Trauth, N.2    Donaldson, D.D.3    Madden, K.B.4    Morris, S.C.5    Collins, M.6    Finkelman, F.D.7
  • 49
    • 0034441170 scopus 로고    scopus 로고
    • Genetically determined disparate innate and adaptive cell-mediated immune responses to pulmonary Mycobacterium bovis BCG infection in C57BL/6 and BALB/c mice
    • Wakeham J., Wang J., and Xing Z. Genetically determined disparate innate and adaptive cell-mediated immune responses to pulmonary Mycobacterium bovis BCG infection in C57BL/6 and BALB/c mice. Infect. Immun. 68 (2000) 6946-6953
    • (2000) Infect. Immun. , vol.68 , pp. 6946-6953
    • Wakeham, J.1    Wang, J.2    Xing, Z.3
  • 50
    • 0034100368 scopus 로고    scopus 로고
    • Interferon-gamma expression in jejunal biopsies in experimental human cryptosporidiosis correlates with prior sensitization and control of oocyst excretion
    • White A.C., Robinson P., Okhuysen P.C., Lewis D.E., Shahab I., Lahoti S., DuPont H.L., and Chappell C.L. Interferon-gamma expression in jejunal biopsies in experimental human cryptosporidiosis correlates with prior sensitization and control of oocyst excretion. J. Infect. Dis. 181 (2000) 701-709
    • (2000) J. Infect. Dis. , vol.181 , pp. 701-709
    • White, A.C.1    Robinson, P.2    Okhuysen, P.C.3    Lewis, D.E.4    Shahab, I.5    Lahoti, S.6    DuPont, H.L.7    Chappell, C.L.8
  • 51
    • 0035117256 scopus 로고    scopus 로고
    • Evidence for the emergence of a type-1-like immune response in intestinal mucosa of calves recovering from cryptosporidiosis
    • Wyatt C.R., Brackett E.J., and Savidge J. Evidence for the emergence of a type-1-like immune response in intestinal mucosa of calves recovering from cryptosporidiosis. J. Parasitol. 87 (2001) 90-95
    • (2001) J. Parasitol. , vol.87 , pp. 90-95
    • Wyatt, C.R.1    Brackett, E.J.2    Savidge, J.3
  • 52
    • 28444442991 scopus 로고    scopus 로고
    • Response of T lymphocytes from previously infected calves to recombinant Cryptosporidium parvum P23 vaccine antigen
    • Wyatt C.R., Lindahl S., Austin K., Kapil S., and Branch J. Response of T lymphocytes from previously infected calves to recombinant Cryptosporidium parvum P23 vaccine antigen. J. Parasitol. 91 (2005) 1239-1242
    • (2005) J. Parasitol. , vol.91 , pp. 1239-1242
    • Wyatt, C.R.1    Lindahl, S.2    Austin, K.3    Kapil, S.4    Branch, J.5
  • 53
    • 0031773982 scopus 로고    scopus 로고
    • Characterization of experimental Cryptosporidium parvum infection in IFN-gamma knockout mice
    • You X., and Mead J.R. Characterization of experimental Cryptosporidium parvum infection in IFN-gamma knockout mice. Parasitology 117 (1998) 525-531
    • (1998) Parasitology , vol.117 , pp. 525-531
    • You, X.1    Mead, J.R.2


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