Tissue distribution of silibinin, the major active constituent of silymarin, in mice and its association with enhancement of phase II enzymes: Implications in cancer chemoprevention

Carcinogenesis

Volumn 20, Issue 11, 1999, Pages 2101-2108

  Zhao, Jifu ^a   Agarwal, Rajesh ^a,b  

^a UNIVERSITY OF COLORADO   (United States)

^b UNIVERSITY OF COLORADO CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCURONIDE; GLUTATHIONE TRANSFERASE; INTESTINE ENZYME; LIVER ENZYME; LUNG ENZYME; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); SILIBININ; SILYMARIN; SULFATE;

ANIMAL EXPERIMENT; ARTICLE; CANCER PREVENTION; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; DRUG BIOAVAILABILITY; DRUG CONJUGATION; DRUG HALF LIFE; DRUG LIVER LEVEL; DRUG STRUCTURE; ENZYME ACTIVITY; INTRAVENOUS DRUG ADMINISTRATION; LIVER; LUNG; MALE; MOUSE; NONHUMAN; ORAL DRUG ADMINISTRATION; PANCREAS; PRIORITY JOURNAL; PROSTATE; SKIN; SMALL INTESTINE; STOMACH; TISSUE DISTRIBUTION;

ANIMALS; ANTICARCINOGENIC AGENTS; CALIBRATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; ELECTROCHEMISTRY; ENZYME INDUCTION; FEMALE; GLUTATHIONE TRANSFERASE; MALE; MICE; MICE, INBRED SENCAR; NAD(P)H DEHYDROGENASE (QUINONE); NEOPLASMS, EXPERIMENTAL; SILYMARIN; SPECTROPHOTOMETRY, ULTRAVIOLET; TISSUE DISTRIBUTION;

EID: 0032717556     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/20.11.2101     Document Type: Article

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