The proline-rich N-terminal sequence of calcineurin Aβ determines substrate binding

Biochemistry

Volumn 48, Issue 9, 2009, Pages 1900-1910

  Kilka, Susann ^a   Erdmann, Frank ^a   Migdoll, Alexander ^a   Fischer, Gunter ^a,b   Weiwad, Matthias ^a,b  

^a MAX PLANCK RESEARCH UNIT FOR ENZYMOLOGY OF PROTEIN FOLDING   (Germany)

^b NONE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CALCINEURIN; CATALYTIC EFFICIENCIES; CATALYTIC SUBUNITS; CELL LINES; DEPHOSPHORYLATES; DEPHOSPHORYLATION; HETERODIMERS; HUMAN GENOMES; ISOFORM; ISOFORMS; KINETIC ANALYSIS; N TERMINALS; PHYSIOLOGICAL FUNCTIONS; PROTEIN PHOSPHATASE; PROTEIN SUBSTRATES; REGULATORY SUBUNITS; REPORTER GENES; SUBCELLULAR DISTRIBUTIONS; SUBSTRATE AFFINITIES; SUBSTRATE BINDINGS; SUBSTRATE RECOGNITION; SUBSTRATE SPECIFICITIES; TURN-OVER NUMBERS;

AMINES; CALCIUM; CELL CULTURE; DISTRIBUTION FUNCTIONS; TRANSCRIPTION; TRANSCRIPTION FACTORS;

SUBSTRATES;

CALCINEURIN; CALCINEURIN A BETA; CALCINEURIN ALPHA; CALCINEURIN BETA; CALCINEURIN GAMMA; ISOENZYME; PHOSPHOPROTEIN DARPP 32; PROLINE; TAU PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR ELK 1; TRANSCRIPTION FACTOR ELK 7; TRANSCRIPTION FACTOR NFAT; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; CATALYSIS; CONTROLLED STUDY; DEPHOSPHORYLATION; ENZYME SPECIFICITY; HUMAN; HUMAN CELL; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; SEQUENCE ANALYSIS;

AMINO ACID SEQUENCE; BINDING SITES; BLOTTING, WESTERN; CALCINEURIN; CATALYSIS; CATALYTIC DOMAIN; CELL LINE; CELL LINE, TUMOR; ETS-DOMAIN PROTEIN ELK-1; HELA CELLS; HUMANS; ISOENZYMES; JURKAT CELLS; KINETICS; LUCIFERASES; MICROSCOPY, CONFOCAL; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NFATC TRANSCRIPTION FACTORS; PHOSPHORYLATION; PROLINE; PROTEIN MULTIMERIZATION; RECOMBINANT FUSION PROTEINS; SUBSTRATE SPECIFICITY; TRANSFECTION;

CANA;

EID: 64549162793     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi8019355     Document Type: Article

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