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Volumn 165, Issue 5, 2004, Pages 1755-1765

Calcineurin A-α but not A-β is required for normal kidney development and function

Author keywords

[No Author keywords available]

Indexed keywords

CALCINEURIN; CALCINEURIN A ALPHA; CALCINEURIN A BETA; UNCLASSIFIED DRUG;

EID: 7244250009     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9440(10)63430-X     Document Type: Article
Times cited : (61)

References (35)
  • 1
    • 0033779701 scopus 로고    scopus 로고
    • Calcineurin: Form and function
    • Rusnak F, Mertz P: Calcineurin: form and function. Physiol Rev 2000 80:1433-1521
    • (2000) Physiol Rev , vol.80 , pp. 1433-1521
    • Rusnak, F.1    Mertz, P.2
  • 2
    • 0037123924 scopus 로고    scopus 로고
    • Angiotensin II induces myocyte enhancer factor 2- And calcineurin/nuclear factor of activated T cell-dependent transcriptional activation in vascular myocytes
    • Suzuki E, Nishimatsu H, Satonaka H, Walsh K, Goto A, Omata M, Fujita T, Nagai R, Hirata Y: Angiotensin II induces myocyte enhancer factor 2- and calcineurin/nuclear factor of activated T cell-dependent transcriptional activation in vascular myocytes. Circ Res 2002, 90:1004-1011
    • (2002) Circ Res , vol.90 , pp. 1004-1011
    • Suzuki, E.1    Nishimatsu, H.2    Satonaka, H.3    Walsh, K.4    Goto, A.5    Omata, M.6    Fujita, T.7    Nagai, R.8    Hirata, Y.9
  • 3
    • 0034731464 scopus 로고    scopus 로고
    • Calcineurin blockade prevents cardiac mitogen-activated protein kinase activation and hypertrophy in renovascular hypertension
    • Mural A, Pellieux C, Brunner H-R, Pedrazzini T: Calcineurin blockade prevents cardiac mitogen-activated protein kinase activation and hypertrophy in renovascular hypertension. J Biol Chem 2000, 275:40867-40873
    • (2000) J Biol Chem , vol.275 , pp. 40867-40873
    • Mural, A.1    Pellieux, C.2    Brunner, H.-R.3    Pedrazzini, T.4
  • 4
    • 0036287989 scopus 로고    scopus 로고
    • Angiotensin II stimulates calcineurin activity in proximal tubule epithelia through AT-1 receptor-mediated tyrosine phosphorylation of the PLC-γ1 isoform
    • Lea J, Kin S, Roberts B, Shuler M, Marrero M, Tumlin J: Angiotensin II stimulates calcineurin activity in proximal tubule epithelia through AT-1 receptor-mediated tyrosine phosphorylation of the PLC-γ1 isoform. J Am Soc Nephrol 2002, 13:1750-1756
    • (2002) J Am Soc Nephrol , vol.13 , pp. 1750-1756
    • Lea, J.1    Kin, S.2    Roberts, B.3    Shuler, M.4    Marrero, M.5    Tumlin, J.6
  • 5
    • 0035834677 scopus 로고    scopus 로고
    • Insulin-like growth factor-1 induces renal cell hypertrophy via a calcineurin-dependent mechanism
    • Gooch JL, Tang Y, Ricono JM, Abboud HE: Insulin-like growth factor-1 induces renal cell hypertrophy via a calcineurin-dependent mechanism. J Biol Chem 2001, 276:42492-42500
    • (2001) J Biol Chem , vol.276 , pp. 42492-42500
    • Gooch, J.L.1    Tang, Y.2    Ricono, J.M.3    Abboud, H.E.4
  • 6
    • 0033526991 scopus 로고    scopus 로고
    • IGF-1 induces skeletal myocyte hypertrophy in association with GATA-2 and NF-ATc1
    • Musaro A, McCullagh KJ, Naya FJ, Olsen EN, Rosenthal N: IGF-1 induces skeletal myocyte hypertrophy in association with GATA-2 and NF-ATc1. Nature 1999, 400:581-585
    • (1999) Nature , vol.400 , pp. 581-585
    • Musaro, A.1    McCullagh, K.J.2    Naya, F.J.3    Olsen, E.N.4    Rosenthal, N.5
  • 7
    • 0034623956 scopus 로고    scopus 로고
    • Insulin-like growth factor-I stimulates dephosphorylation of IkB through the serine phosphatase calcineurin (protein phosphatase 2B)
    • Pons S, Torres-Aleman I: Insulin-like growth factor-I stimulates dephosphorylation of IkB through the serine phosphatase calcineurin (protein phosphatase 2B). J Biol Chem 2000, 275:38620-38625
    • (2000) J Biol Chem , vol.275 , pp. 38620-38625
    • Pons, S.1    Torres-Aleman, I.2
  • 9
    • 2442520434 scopus 로고    scopus 로고
    • Involvement of calcineurin in TGFβ-mediated regulation of extracellular matrix accumulation
    • Gooch JL, Gorin Y, Zhang BX, Abboud HE: Involvement of calcineurin in TGFβ-mediated regulation of extracellular matrix accumulation. J Biol Chem 2004, 279:15561-15570
    • (2004) J Biol Chem , vol.279 , pp. 15561-15570
    • Gooch, J.L.1    Gorin, Y.2    Zhang, B.X.3    Abboud, H.E.4
  • 12
    • 0029798880 scopus 로고    scopus 로고
    • Reduction of calcineurin anzymatic activity in Alzheimer's disease: Correlation with neuropathologic changes
    • Ladner C, Czech J, Maurice J, Lorens S, Lee J: Reduction of calcineurin anzymatic activity in Alzheimer's disease: correlation with neuropathologic changes. J Neuropathol Exp Neurol 1996, 55:924-931
    • (1996) J Neuropathol Exp Neurol , vol.55 , pp. 924-931
    • Ladner, C.1    Czech, J.2    Maurice, J.3    Lorens, S.4    Lee, J.5
  • 14
    • 0033982992 scopus 로고    scopus 로고
    • Calcineruin-mediated hypertrophy protects cardiomyocytes from apoptosis in vitro and in vivo: An apoptosis-independent model of dilated heart failure
    • DeWindt J, Lim H, Taigen T, Wencker D, Condorelli G, Dorn Gn, Kitsis R, Molkentin J: Calcineruin-mediated hypertrophy protects cardiomyocytes from apoptosis in vitro and in vivo: an apoptosis-independent model of dilated heart failure. Circ Res 2000, 86:255-263
    • (2000) Circ Res , vol.86 , pp. 255-263
    • DeWindt, J.1    Lim, H.2    Taigen, T.3    Wencker, D.4    Condorelli, G.5    Gn, D.6    Kitsis, R.7    Molkentin, J.8
  • 15
    • 0033981108 scopus 로고    scopus 로고
    • Targeted inhibition of calcineurin prevents agonist-induced cardiomyocyte hypertrophy
    • Taigen T, De Windt LJ, Lim HW, Molkenten JD: Targeted inhibition of calcineurin prevents agonist-induced cardiomyocyte hypertrophy. Proc Natl Acad Sci USA 2000, 97:1196-1201
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 1196-1201
    • Taigen, T.1    De Windt, L.J.2    Lim, H.W.3    Molkenten, J.D.4
  • 16
    • 0032892816 scopus 로고    scopus 로고
    • Cyclosporin exerts a direct fibrogenic effect on human tubuloin-terstitial cells: Roles of insulin-like growth factor I, transforming growth factor β1, and platelet-derived growth factor
    • Johnson DW, Saunders HJ, Johnson FJ, Huq SO, Field MJ, Pollock CA: Cyclosporin exerts a direct fibrogenic effect on human tubuloin-terstitial cells: roles of insulin-like growth factor I, transforming growth factor β1, and platelet-derived growth factor. J Pharmacol Exp Ther 1999, 289:535-542
    • (1999) J Pharmacol Exp Ther , vol.289 , pp. 535-542
    • Johnson, D.W.1    Saunders, H.J.2    Johnson, F.J.3    Huq, S.O.4    Field, M.J.5    Pollock, C.A.6
  • 17
    • 0025626093 scopus 로고
    • Cyclosporin A stimulates transcription and procollagen secretion in tubulointersititial fibroblasts and proximal tubule cells
    • Wolf G, Killen PD, Neilson EG: Cyclosporin A stimulates transcription and procollagen secretion in tubulointersititial fibroblasts and proximal tubule cells. J Am Soc Nephol 1990, 6:918-922
    • (1990) J Am Soc Nephol , vol.6 , pp. 918-922
    • Wolf, G.1    Killen, P.D.2    Neilson, E.G.3
  • 19
    • 0030945154 scopus 로고    scopus 로고
    • Cytoskeletal changes in the brains of mice lacking calcineurin A α
    • Kayyali U, Zhang W, Yee A, Seidman J, Potter H: Cytoskeletal changes in the brains of mice lacking calcineurin A α. J Neurochem 1997, 68:1668-1678
    • (1997) J Neurochem , vol.68 , pp. 1668-1678
    • Kayyali, U.1    Zhang, W.2    Yee, A.3    Seidman, J.4    Potter, H.5
  • 22
    • 0036000926 scopus 로고    scopus 로고
    • Calcineurin Aα plays an exclusive role in TCR signaling in mature but not immature T cells
    • Chan VS, Wong C, Ohashi PS: Calcineurin Aα plays an exclusive role in TCR signaling in mature but not immature T cells. Eur J Immunol 2002, 32:1223-1229
    • (2002) Eur J Immunol , vol.32 , pp. 1223-1229
    • Chan, V.S.1    Wong, C.2    Ohashi, P.S.3
  • 25
    • 0037979119 scopus 로고    scopus 로고
    • Altered skeletal muscle phenotypes in calcineurin Aα and Aβ gene-targeted mice
    • Parsons SA, Wilkins BJ, Bueno OF, Molkentin JD: Altered skeletal muscle phenotypes in calcineurin Aα and Aβ gene-targeted mice. Mol Cell Biol 2003, 23:4331-4343
    • (2003) Mol Cell Biol , vol.23 , pp. 4331-4343
    • Parsons, S.A.1    Wilkins, B.J.2    Bueno, O.F.3    Molkentin, J.D.4
  • 26
    • 0035967887 scopus 로고    scopus 로고
    • Signals transduced by Ca(2+)/calcineurin and NFATc3/c4 pattern the developing vasculature
    • Graef I, Chen F, Chen L, Kuo A, Crabtree G: Signals transduced by Ca(2+)/calcineurin and NFATc3/c4 pattern the developing vasculature. Cell 2001, 105:863-875
    • (2001) Cell , vol.105 , pp. 863-875
    • Graef, I.1    Chen, F.2    Chen, L.3    Kuo, A.4    Crabtree, G.5
  • 28
    • 0031958909 scopus 로고    scopus 로고
    • Expression of the cyclin kinase inhibitor, p27kip1, in developing and mature human kidney
    • Combs HL, Shankland SJ, Setzer SV, Hudkins KL, Alpers CE: Expression of the cyclin kinase inhibitor, p27kip1, in developing and mature human kidney. Kidney Int 1998, 53:892-896
    • (1998) Kidney Int , vol.53 , pp. 892-896
    • Combs, H.L.1    Shankland, S.J.2    Setzer, S.V.3    Hudkins, K.L.4    Alpers, C.E.5
  • 29
    • 0036569798 scopus 로고    scopus 로고
    • Deregulated expression of the homeobox gene Cux-1 in transgenic mice results in downregulation of p27(kip1) expression during nephrogenesis, glomerular abnormalities, and multiorgan hyperplasia
    • Ledford AW, Brantley JG, Kemeny G, Foreman TL, Quaggin SE, Igarashi P, Oberhaus SM, Rodova M, Calvet JP, Vanden Heuvel GB: Deregulated expression of the homeobox gene Cux-1 in transgenic mice results in downregulation of p27(kip1) expression during nephrogenesis, glomerular abnormalities, and multiorgan hyperplasia. Dev Biol 2002, 245:157-171
    • (2002) Dev Biol , vol.245 , pp. 157-171
    • Ledford, A.W.1    Brantley, J.G.2    Kemeny, G.3    Foreman, T.L.4    Quaggin, S.E.5    Igarashi, P.6    Oberhaus, S.M.7    Rodova, M.8    Calvet, J.P.9    Vanden Heuvel, G.B.10
  • 30
    • 0037378488 scopus 로고    scopus 로고
    • Cux-1 transgenic mice develop glomerulosclerosis and interstitial fibrosis
    • Brantley JG, Sharma M, Alcalay NI, Heuvel GB: Cux-1 transgenic mice develop glomerulosclerosis and interstitial fibrosis. Kidney Int 2003, 63:1240-1248
    • (2003) Kidney Int , vol.63 , pp. 1240-1248
    • Brantley, J.G.1    Sharma, M.2    Alcalay, N.I.3    Heuvel, G.B.4
  • 31
    • 0028798968 scopus 로고
    • Expression of calcineurin activity and α-subunit isoforms in specific segments of the rat nephron
    • Tumlin JA, Someren JT, Swanson CE, Lea JP: Expression of calcineurin activity and α-subunit isoforms in specific segments of the rat nephron. Am J Physiol 1995, 269:F558-F563
    • (1995) Am J Physiol , vol.269
    • Tumlin, J.A.1    Someren, J.T.2    Swanson, C.E.3    Lea, J.P.4
  • 32
    • 0345530114 scopus 로고    scopus 로고
    • Cyclosporin A administration during pregnancy induces a permanent nephron deficit in young rabbits
    • Tendron A, Decramer S, Justrabo E, Gouyon JB, Semama DS, Gilbert T: Cyclosporin A administration during pregnancy induces a permanent nephron deficit in young rabbits. J Am Soc Nephrol 2003, 14:3188-3196
    • (2003) J Am Soc Nephrol , vol.14 , pp. 3188-3196
    • Tendron, A.1    Decramer, S.2    Justrabo, E.3    Gouyon, J.B.4    Semama, D.S.5    Gilbert, T.6
  • 33
    • 2142704366 scopus 로고    scopus 로고
    • Calcineurin is required in urinary tract mesenchyme for the development of the pyeloureteral peristaltic machinery
    • Chang CP, McDill BW, Neilson JR, Joist HE, Epstein JA, Crabtree GR, Chen F: Calcineurin is required in urinary tract mesenchyme for the development of the pyeloureteral peristaltic machinery. J Clin Invest 2004. 113:1051-1058
    • (2004) J Clin Invest , vol.113 , pp. 1051-1058
    • Chang, C.P.1    McDill, B.W.2    Neilson, J.R.3    Joist, H.E.4    Epstein, J.A.5    Crabtree, G.R.6    Chen, F.7
  • 34
    • 0030010591 scopus 로고    scopus 로고
    • Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors
    • Nakayama K, Ishida N, Shirane M, Inomata A, Inoue T, Shishido N, Horii I, Loh DY: Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors. Cell 1996, 85:707-720
    • (1996) Cell , vol.85 , pp. 707-720
    • Nakayama, K.1    Ishida, N.2    Shirane, M.3    Inomata, A.4    Inoue, T.5    Shishido, N.6    Horii, I.7    Loh, D.Y.8
  • 35
    • 0037215135 scopus 로고    scopus 로고
    • Calcineurin is activated in diabetes and is required for glomerular hypertrophy and ECM accumulation
    • Gooch JL, Barnes JL, Garcia S, Abboud HE: Calcineurin is activated in diabetes and is required for glomerular hypertrophy and ECM accumulation. Am J Physiol Renal Physiol 2003, 284:F144-F154
    • (2003) Am J Physiol Renal Physiol , vol.284
    • Gooch, J.L.1    Barnes, J.L.2    Garcia, S.3    Abboud, H.E.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.