Chronic ingestion of apple pectin can enhance the absorption of quercetin

Journal of Agricultural and Food Chemistry

Volumn 57, Issue 6, 2009, Pages 2583-2587

  Nishijima, Tomohiko ^a,b   Iwai, Kunihisa ^b   Saito, Yasuo ^a   Takida, Yoshiki ^a   Matsue, Hajime ^b  

^a Glico Dairy Products Co Ltd   (Japan)

^b AOMORI UNIVERSITY OF HEALTH AND WELFARE   (Japan)

Author keywords

Apple pectin; Bioavailability; Intestine; Quercetin; Rutin

Indexed keywords

PECTIN; QUERCETIN; RUTOSIDE;

ANIMAL; APPLE; ARTICLE; BIOAVAILABILITY; CHEMISTRY; DIET; DRUG EFFECT; FRUIT; INTESTINE ABSORPTION; MALE; RAT; WISTAR RAT;

ANIMALS; BIOLOGICAL AVAILABILITY; DIET; FRUIT; INTESTINAL ABSORPTION; MALE; MALUS; PECTINS; QUERCETIN; RATS; RATS, WISTAR; RUTIN;

MALUS X DOMESTICA; RATTUS;

EID: 64549157596     PISSN: 00218561     EISSN: None     Source Type: Journal    
DOI: 10.1021/jf803547h     Document Type: Article

References (27)

1. Piskula, M. K. Factors affecting flavonoids absorption. Biofactors 2000, 12, 175-180.
2. Scalbert, A.; Williamson, G. Dietary intake and bioavailability of polyphenols. J. Nutr. 2000, 130, 2073S-2085S.
3. Manach, C.; Williamson, G.; Morand, C.; Scalbert, A.; Remesy, C. Bioavailability and bioefficacy of polyphenols in humans. I. Review of 97 bioavailability studies. Am. J. Clin. Nutr. 2005, 81, 230S-242S.
4. Bravo, L. Polyphenols: Chemistry, dietary sources, metabolism, and nutritional significance. Nutr. Rev. 1998, 56, 317-333.
5. Tamura, M.; Hirayama, K.; Itoh, K. Role of intestinal flora on the metabolism, absorption, and biological activity of dietary flavonoids. Biosci. Microflora 2003, 22, 125-131.
6. Setchell, K. D. R.; Brown, N. M.; Zinmmer-Nechemias, L.; Brashear, W. T.; Wolfe, B. E.; Kirschner, A. S.; Heubi, J. E. Evidence for lack of absorption of soy isoflavone glycosides in humans, supporting the crucial role of intestinal metabolism for bioavailability. Am. J. Clin. Nutr. 2002, 76, 447-453.
7. Day, A. J.; Gee, J. M.; Dupont, M. S.; Johnson, I. T.; Williamson, G. Absorption of quercetin-3-glucoside and quercetin-4′-glucoside in the rat small intestine: the role of lactase phlorizin hydrolase and the sodium-dependent glucose transporter. Biochem. Pharmacol. 2003, 65, 1199-1206.
8. Azuma, K.; Ippoushi, K.; Ito, H.; Horie, H.; Terao, J. Enhancing effect of lipids and emulsifiers on the accumulation of quercetin metabolites in blood plasma after the short-term ingestion of onion by rats. Biosci., Biotechnol., Biochem. 2003, 67, 2548-2555.
9. Matsumoto, M.; Matsukawa, N.; Chiji, H.; Hara, H. Difructose anhydride III promotes absorption of the soluble flavonoid αG-rutin in rats. J. Agric. Food Chem. 2007. 55, 4202-4208.
10. Morand, C.; Crespy, V.; Manach, C.; Besson, C.; Demigne, C.; Remesy, C. Plasma metabolites of quercetin and their antioxidant properties. Am. J. Physiol 1998, 275, 212-219.
11. Hollman, P. C.; van Trijp, J. M.; Buysman, M. N.; van der Gaag, M. S.; Mengelers, M. J.; de Vries, J. H.; Katan, M. B. Relative bioavailability of the antioxidant flavonoid quercetin from various foods in man. FEBS Lett. 1997. 418, 152-156.
12. Story, J. A. Modification of steroid excretion in response to dietary fiber. In Dietary Fiber, Vahouny, G. V., Kritchevsky, D., Eds.; Plenum: New York, 1986; pp 253-264.
13. Fleming, S. E.; Lee, B. Growth performance and intestinal transit time of rats fed purified and natural dietary fibers. J. Nutr. 1983. 113, 592-601.
14. Dongowski, G.; Lorenz, A.; Proll, J. The degree of methylation influences the degradation of pectin in the intestinal tract of rats and in vitro. J. Nutr. 2002, 132, 1935-1944.
15. Chun, W.; Bamba, T.; Hosoda, S. Effect of pectin, a soluble dietary fiber, on functional and morphological parameters of the small intestine in rats. Digestion 1989, 42, 22-29.
16. Dongowski, G.; Lorenz, A. Intestinal steroids in rats are influenced by the structural parameters of pectin. J. Nutr. Biochem. 2004, 15, 196-205.
17. Fernandez, M. L. Distinct mechanisms of plasma LDL lowering by dietary fiber in the guinea pig: Specific effects of pectin, guar gum, and psyllium. J. Lipid Res. 1995, 36, 2394-2404.
18. Rock, C. L.; Swendseid, M. E. Plasma β-carotene response in humans after meals supplemented with dietary pectin. Am. J. Clin. Nutr. 1992, 55, 96-99.
19. Reeves, P. G.; Nielsen, F. H.; Fahey, G. C., Jr. AIN-93 purified diets for laboratory rodents: Final report of the American Institute of Nutrition ad hoc writing committee on the reformulation of the AIN-76A rodent diet. J. Nutr. 1993, 123, 1939-1951.
20. Hollman, P. C.; Bijsman, M. N.; van Gameren, Y.; Cnossen, E. P.; de Vries, J. H.; Kantan, M. B. The sugar moiety is a major determinant of the absorption of dietary flavonoid glycosides in man. Free. Radical Res. 1999, 31, 569-573.
21. Day, A. J.; Dupont, M. S.; Ridley, S.; Rhodes, M.; Rhodes, M. J.; Morgan, M. R.; Williamson, G. Deglycosylation of flavonoid and isoflavonoid glycosides by human small intestine and liver β-glucosidase activity. FEBS Lett. 1998, 436, 71-75.
22. Tamura, M.; Nakagawa, T.; Tsushida, T.; Hirayama, K.; Itoh, K. Effect of pectin enhancement on plasma quercetin and fecal flora in rutin-supplemented mice. J. Food Sci 2007, 72, S648-651.
23. Farness, P. L.; Schneeman, B. O. Effects of dietary cellulose, pectin and oat bran on the small intestine. J. Nutr. 1982, 112, 1315-1319.
24. Tamura, M.; Suzuki, H. Effects of pectin on jejunal and ileal morphology and ultrastructure in adult mice. Am. Nutr. Metab. 1997, 41, 255-259.b
25. Sigleo, S.; Jackson, M. J.; Vahouny, G. V. Effects of dietary fiber constituents on intestinal morphology and nutrient transport. Am. J. Physiol. 1984, 246, G34-39.
26. Kim, D.-H.; Jung, E.-A.; Sohng, I.-S.; Han, J.-A.; Kim, T.-H.; Han, M. J. Intestinal bacterial metabolism of flavonoids and its relation to some biological activities. Arch, Pharm. Res. 1998. 21, 17-23.
27. Blaut, M.; Schoefer, L.; Braune, A. Transformation of flavonoids by intestinal microorganisms. Int. J. Vitam. Nutr. Res. 2003, 73, 79-87.