Normal cellular prior protein is preferentially expressed on subpopulations of murine hemopoietic cells

Journal of Immunology

Volumn 166, Issue 6, 2001, Pages 3733-3742

  Liu, T ^a   Li, R ^a   Wong, B S ^a   Liu, D ^a   Pan, T ^a   Petersen, R B ^a   Gambetti, P ^a   Sy, M S ^a  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; IMMUNOGLOBULIN M; INTERLEUKIN 7 RECEPTOR; LEUKOSIALIN; PRION PROTEIN; CD45 ANTIGEN; LEUKOCYTE ANTIGEN; LYMPHOCYTE ANTIGEN RECEPTOR; PHORBOL 13 ACETATE 12 MYRISTATE; SIALOGLYCOPROTEIN; SPN PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; B LYMPHOCYTE; BONE MARROW CELL; CELL DIFFERENTIATION; CELL SUBPOPULATION; CONTROLLED STUDY; FLOW CYTOMETRY; HEMATOPOIETIC CELL; LYMPHOID ORGAN; LYMPHOID TISSUE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PATHOGENESIS; PHENOTYPE; PRION DISEASE; PRIORITY JOURNAL; PROTEIN EXPRESSION; STEM CELL; THYMOCYTE; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; CELL DIVISION; CYTOLOGY; DRUG EFFECT; GENE; GENETICS; GRANULOCYTE; HEMATOPOIETIC STEM CELL; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; METABOLISM; MOUSE MUTANT; SPLEEN; T LYMPHOCYTE SUBPOPULATION; THYMUS;

ANIMALS; ANTIGENS, CD; ANTIGENS, CD43; ANTIGENS, CD45; B-LYMPHOCYTE SUBSETS; BONE MARROW CELLS; CELL DIFFERENTIATION; CELL DIVISION; GENES, RAG-1; GRANULOCYTES; HEMATOPOIETIC STEM CELLS; IMMUNOGLOBULIN M; LYMPHOCYTE ACTIVATION; LYMPHOID TISSUE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PRPC PROTEINS; RECEPTORS, ANTIGEN, B-CELL; RECEPTORS, INTERLEUKIN-7; SIALOGLYCOPROTEINS; SPLEEN; T-LYMPHOCYTE SUBSETS; TETRADECANOYLPHORBOL ACETATE; THYMUS GLAND;

EID: 0035866560     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.166.6.3733     Document Type: Article

References (61)

1. Prion protein biology
2. Prion protein gene variation among primates
3. Scrapie prion protein contains a phosphatidylinositol glycolipid
4. Prions and prion proteins
5. Infectious amiloids: Subacute spongiform encephalopathies as transmissible cerebral amyloidoses
6. Creutzfeldt-Jakob disease and related transmissible spongiform encephalopathies
7. Prions
8. Conversion of α-helices into β-sheets features in the formation of the scrapie prion proteins
9. Conformational transitions, dissociation, and unfolding of scrapie amyloid (prion) protein
10. Secondary structure analysis of the scrapie-associated protein PrP 27-30 in water by infrared spectroscopy
11. Nearly ubiquitous tissue distribution of the scrapie agent precursor protein
12. Detection of prion protein mRNA in normal and scrapie-infected tissues and cell lines
13. The prion protein gene: A role in mouse embryogenesis?
14. Regulation of the glial fibrillary acidic protein, β actin and prion protein mRNAs during brain development in mouse
15. Normal development and behavior of mice lacking the neuronal cell-surface PrP protein
16. 129/Ola mice carrying a null mutation in PrP that abolishes mRNA production are developmentally normal
17. Doxycycline control of prion protein transgene expression modulates prion disease in mice
18. Mice devoid of PrP are resistant to scrapie
19. Ablation of the prion protein (PrP) gene in mice prevents scrapie and facilitates production of anti-PrP antibodies
20. The cellular prion protein binds copper in vivo
21. Copper binding to the N-terminal tandem repeat region of mammalian and avian prion protein: Structural studies using synthetic peptides
22. Prion protein selectively binds copper(II) ions
23. Copper binding to the prion protein: Structural implications of four identical cooperative binding sites
24. Normal prion protein has an activity like that of superoxide dismutase
25. Differential contribution of superoxide dismutase activity by prion protein in vivo
26. Effects of copper on survival of prion protein knockout neurons and glia
27. Prion disease: A loss of antioxidant function?
28. Pathogenesis of experimental scrapie
29. Pathogenesis of scrapie in mice after intragastric infection
30. Pathogenesis of mouse scrapie: Dynamics of agent replication in spleen, spinal cord and brain after infection by different routes
31. Effect of vaccinia-activated macrophages on scrapie infection in hamsters
32. Mitogenic stimulation of the host enhances susceptibility to scrapie
33. SCID mouse spleen does not support scrapie agent replication
34. Replication of scrapie in spleens of SCID mice follows reconstitution with wild-type mouse bone marrow
35. Scrapie replication in lymphoid tissues depends on prion protein-expressing follicular dendritic cells
36. Impaired prion replication in spleens of mice lacking functional follicular dendritic cells
37. Self-renewal, differentiation or death: Regulation and manipulation of hematopoietic stem cell fate
38. The biology of hematopoietic stem cells
39. Developmental potential and dynamic behavior of hematopoietic stem cells
40. Identification of clonogenic common lymphoid progenitors in mouse bone marrow
41. A clonogenic common myeloid progenitor that gives rise to all myeloid lineages
42. Expression of CD43 on murine and human pluripotent hematopoietic stem cells
43. Resolution and characterization of pro-B and pre-pro-B cell stages in normal mouse bone marrow
44. Expression and function of the interleukin 7 receptor in murine lymphocytes
45. Lymphoid development from hematopoietic stem cells
46. Prion protein expression in different species: Analysis with a panel of new mAbs
47. Identification of an epitope in the C terminus of normal prion protein whose expression is modulated by binding events in the N terminus
48. Murine B lymphopoiesis: Towards a unified model
49. The role of cytokine receptor signaling in lymphocyte development
50. Murine thymocytes proliferate in direct response to interleukin-7
51. IL-2 receptor α chain (CD25, TAC) expression defines a crucial stage in pre-B cell development
52. The expression of Vpre-B/λ5 surrogate light chain in early bone marrow precursor B cells of normal and B cell-deficient mutant mice
53. Sialophorin (CD43) and the Wiskott-Aldrich syndrome
54. RAG-1-deficient mice have no mature B and T lymphocytes
55. Characterization and regulation of RB6-8C5 antigen expression on murine bone marrow cells
56. Selective expression of Ly-6G on myeloid lineage cells in mouse bone marrow: RB6-8C5 mAb to granulocyte-differentiation antigen (Gr-1) detects members of the Ly-6 family
57. Thymic stem cells in mouse bone marrow
58. Transplantable NK cell progenitors in murine bone marrow
59. T-lymphocyte activation and the cellular form of the prion protein
60. A crucial role for B cells in neuroinvasive scrapie
61. PrP expression in B lymphocytes is not required for prion neuroinvasion