Rac1 activates HIF-1 in retinal pigment epithelium cells under hypoxia

Graefe's Archive for Clinical and Experimental Ophthalmology

Volumn 247, Issue 5, 2009, Pages 633-639

  Zhang, Peng ^a   Zhang, Xing ^b   Hao, Xiaofeng ^c   Wang, Yusheng ^a   Hui, Yannian ^a   Wang, Haiyan ^a   Hu, Dan ^a   Zhou, Jian ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^c INSTITUTE OF CHINESE MATERIA MEDICA   (China)

Author keywords

Choroidal neovascularization; Growth factors; Hypoxia; Molecular biology; Signal transduction

Indexed keywords

4 AMINO 6 [2 [[4 (DIETHYLAMINO) 1 METHYLBUTYL]AMINO] 6 METHYL 4 PYRIMIDINYL] 2 METHYLQUINOLINE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; MESSENGER RNA; RAC1 PROTEIN;

ARTICLE; CELL HYPOXIA; CONTROLLED STUDY; GENE EXPRESSION; HUMAN; HUMAN CELL; PATHOPHYSIOLOGY; PIGMENT EPITHELIUM; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SUBRETINAL NEOVASCULARIZATION; WESTERN BLOTTING;

AMINOQUINOLINES; ANOXIA; BLOTTING, WESTERN; CELLS, CULTURED; DOWN-REGULATION; GENE EXPRESSION REGULATION; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; IMMUNOENZYME TECHNIQUES; PYRIMIDINES; RAC1 GTP-BINDING PROTEIN; RETINAL PIGMENT EPITHELIUM; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TIME FACTORS;

EID: 64349110094     PISSN: 0721832X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00417-008-1031-0     Document Type: Article

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