메뉴 건너뛰기




Volumn 221, Issue 6, 2007, Pages 411-417

Inhibition of VEGF expression by targeting HIF-1α with small interference RNA in human RPE cells

Author keywords

Choroidal neovascularization; Growth factors; Molecular biology; Retinal pigment epithelium

Indexed keywords

HYPOXIA INDUCIBLE FACTOR 1ALPHA; MESSENGER RNA; SMALL INTERFERING RNA; VASCULOTROPIN;

EID: 35349001759     PISSN: 00303755     EISSN: None     Source Type: Journal    
DOI: 10.1159/000107502     Document Type: Article
Times cited : (62)

References (23)
  • 1
    • 0037899707 scopus 로고    scopus 로고
    • Differential effects of light and alcohol on the electro-oculographic responses of patients with age-related macular disease
    • Arden GB, Wolf JE: Differential effects of light and alcohol on the electro-oculographic responses of patients with age-related macular disease. Invest Ophthalmol Vis Sci 2003;44:3226-3232.
    • (2003) Invest Ophthalmol Vis Sci , vol.44 , pp. 3226-3232
    • Arden, G.B.1    Wolf, J.E.2
  • 2
    • 0032807809 scopus 로고    scopus 로고
    • Polarized vascular endothelial growth factor secretion by human retinal pigment epithelium and localization of vascular endothelial growth factor receptors on the inner choriocapillaris: Evidence for a trophic paracrine relation
    • Blaauwgeers HG, Holtkamp GM, Rutten H, Witmer AN, Koolwijk P, Partanen TA, Alitalo K, Kroon ME, Kijlstra A, van Hinsbergh VW, Schlingemann RO: Polarized vascular endothelial growth factor secretion by human retinal pigment epithelium and localization of vascular endothelial growth factor receptors on the inner choriocapillaris: evidence for a trophic paracrine relation. Am J Pathol 1999;155:421-428.
    • (1999) Am J Pathol , vol.155 , pp. 421-428
    • Blaauwgeers, H.G.1    Holtkamp, G.M.2    Rutten, H.3    Witmer, A.N.4    Koolwijk, P.5    Partanen, T.A.6    Alitalo, K.7    Kroon, M.E.8    Kijlstra, A.9    van Hinsbergh, V.W.10    Schlingemann, R.O.11
  • 3
    • 0028349871 scopus 로고
    • Analysis of lipid deposits extracted from human macular and peripheral Bruch's membrane
    • Holz FG, Sheraidah G, Pauleikhoff D, Bird AC: Analysis of lipid deposits extracted from human macular and peripheral Bruch's membrane. Arch Ophthalmol 1994;112: 402-406.
    • (1994) Arch Ophthalmol , vol.112 , pp. 402-406
    • Holz, F.G.1    Sheraidah, G.2    Pauleikhoff, D.3    Bird, A.C.4
  • 6
    • 0029831672 scopus 로고    scopus 로고
    • Subfoveal fibrovascular membranes in age-related macular degeneration express vascular endothelial growth factor
    • Kvanta A, Algvere PV, Berglin L, Seregard S: Subfoveal fibrovascular membranes in age-related macular degeneration express vascular endothelial growth factor. Invest Ophthalmol Vis Sci 1996;37:1929-1934.
    • (1996) Invest Ophthalmol Vis Sci , vol.37 , pp. 1929-1934
    • Kvanta, A.1    Algvere, P.V.2    Berglin, L.3    Seregard, S.4
  • 8
    • 33745141162 scopus 로고    scopus 로고
    • Oxygen-dependent diseases in the retina: Role of hypoxia-inducible factors
    • Arjamaa O, Nikinmaa M: Oxygen-dependent diseases in the retina: role of hypoxia-inducible factors. Exp Eye Res 2006;83:473-483.
    • (2006) Exp Eye Res , vol.83 , pp. 473-483
    • Arjamaa, O.1    Nikinmaa, M.2
  • 9
    • 0036668791 scopus 로고    scopus 로고
    • Role of apoptosis in the cytotoxic effect mediated by daunorubicin in cultured human retinal pigment epithelial cells
    • Wang YS, Hui YN, Wiedemann P: Role of apoptosis in the cytotoxic effect mediated by daunorubicin in cultured human retinal pigment epithelial cells. J Ocul Pharm Ther 2002;18:377-387.
    • (2002) J Ocul Pharm Ther , vol.18 , pp. 377-387
    • Wang, Y.S.1    Hui, Y.N.2    Wiedemann, P.3
  • 11
    • 0036842215 scopus 로고    scopus 로고
    • Vascular permeability factor/vascular endothelial growth factor: A critical cytokine in tumor angiogenesis and a potential target for diagnosis and therapy
    • Dvorak HF: Vascular permeability factor/vascular endothelial growth factor: a critical cytokine in tumor angiogenesis and a potential target for diagnosis and therapy. J Clin Oncol 2002;20:4368-4380.
    • (2002) J Clin Oncol , vol.20 , pp. 4368-4380
    • Dvorak, H.F.1
  • 12
    • 0035789541 scopus 로고    scopus 로고
    • Regulation of choroid development by the retinal pigment epithelium
    • Zhao S, Overbeek PA: Regulation of choroid development by the retinal pigment epithelium. Mol Vis 2001;7:277-282.
    • (2001) Mol Vis , vol.7 , pp. 277-282
    • Zhao, S.1    Overbeek, P.A.2
  • 13
    • 0036281629 scopus 로고    scopus 로고
    • Detection of inducible nitric oxide synthase and vascular endothelial growth factor in choroidal neovascular membranes
    • Hattenbach LO, Falk B, Nurnberger F, Koch FH, Ohrloff C: Detection of inducible nitric oxide synthase and vascular endothelial growth factor in choroidal neovascular membranes. Ophthalmologica 2002;216: 209-214.
    • (2002) Ophthalmologica , vol.216 , pp. 209-214
    • Hattenbach, L.O.1    Falk, B.2    Nurnberger, F.3    Koch, F.H.4    Ohrloff, C.5
  • 14
    • 33745767945 scopus 로고    scopus 로고
    • Inhibition of hypoxia inducible factor-1alpha (HIF-1alpha) decreases vascular endothelial growth factor (VEGF) secretion and tumor growth in malignant gliomas
    • Jensen RL, Ragel BT, Whang K, Gillespie D: Inhibition of hypoxia inducible factor-1alpha (HIF-1alpha) decreases vascular endothelial growth factor (VEGF) secretion and tumor growth in malignant gliomas. J Neurooncol 2006;78:233-247.
    • (2006) J Neurooncol , vol.78 , pp. 233-247
    • Jensen, R.L.1    Ragel, B.T.2    Whang, K.3    Gillespie, D.4
  • 15
    • 30944442431 scopus 로고    scopus 로고
    • Small interfering RNA expression vector targeting hypoxia-inducible factor 1 alpha inhibits tumor growth in hepatobiliary and pancreatic cancers
    • Mizuno T, Nagao M, Yamada Y, Narikiyo M, Ueno M, Miyagishi M, Taira K, Nakajima Y: Small interfering RNA expression vector targeting hypoxia-inducible factor 1 alpha inhibits tumor growth in hepatobiliary and pancreatic cancers. Cancer Gene Ther 2006; 13:131-140.
    • (2006) Cancer Gene Ther , vol.13 , pp. 131-140
    • Mizuno, T.1    Nagao, M.2    Yamada, Y.3    Narikiyo, M.4    Ueno, M.5    Miyagishi, M.6    Taira, K.7    Nakajima, Y.8
  • 16
    • 0038748037 scopus 로고    scopus 로고
    • Small interfering RNA (siRNA) targeting VEGF effectively inhibits ocular neovascularization in a mouse model
    • Reich SJ, Fosnot J, Kuroki A, Tang W, Yang X, Maguire AM, Bennett J, Tolentino MJ: Small interfering RNA (siRNA) targeting VEGF effectively inhibits ocular neovascularization in a mouse model. Mol Vis 2003;9: 210-216.
    • (2003) Mol Vis , vol.9 , pp. 210-216
    • Reich, S.J.1    Fosnot, J.2    Kuroki, A.3    Tang, W.4    Yang, X.5    Maguire, A.M.6    Bennett, J.7    Tolentino, M.J.8
  • 17
    • 33748117817 scopus 로고    scopus 로고
    • Inhibition of choroidal neovascularization by adenovirus-mediated delivery of short hairpin RNAs targeting VEGF as a potential therapy for AMD
    • Cashman SM, Bowman L, Christofferson J, Kumar-Singh R: Inhibition of choroidal neovascularization by adenovirus-mediated delivery of short hairpin RNAs targeting VEGF as a potential therapy for AMD. Invest Ophthalmol Vis Sci 2006;47:3496-3504.
    • (2006) Invest Ophthalmol Vis Sci , vol.47 , pp. 3496-3504
    • Cashman, S.M.1    Bowman, L.2    Christofferson, J.3    Kumar-Singh, R.4
  • 18
    • 0032053169 scopus 로고    scopus 로고
    • Oxygen sensing, hypoxia-inducible factor-1 and the regulation of mammalian gene expression
    • Ratcliffe PJ, O'Rourke JF, Maxwell PH, Pugh CW: Oxygen sensing, hypoxia-inducible factor-1 and the regulation of mammalian gene expression. J Exp Biol 1998;201:1153-1162.
    • (1998) J Exp Biol , vol.201 , pp. 1153-1162
    • Ratcliffe, P.J.1    O'Rourke, J.F.2    Maxwell, P.H.3    Pugh, C.W.4
  • 19
    • 0037197914 scopus 로고    scopus 로고
    • RNA interference by expression of short-interfering RNAs and hairpin RNAs in mammalian cells
    • Yu JY, DeRuiter SL, Turner DL: RNA interference by expression of short-interfering RNAs and hairpin RNAs in mammalian cells. Proc Natl Acad Sci USA 2002;99:6047-6052.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 6047-6052
    • Yu, J.Y.1    DeRuiter, S.L.2    Turner, D.L.3
  • 21
    • 0034648765 scopus 로고    scopus 로고
    • Angiogenesis in cancer and other diseases
    • Carmeliet P, Jain RK: Angiogenesis in cancer and other diseases. Nature 2000;407:249-257.
    • (2000) Nature , vol.407 , pp. 249-257
    • Carmeliet, P.1    Jain, R.K.2
  • 22
    • 0035910429 scopus 로고    scopus 로고
    • Identification of hypoxia-inducible factor 1 ancillary sequence and its function in vascular endothelial growth factor gene induction by hypoxia and nitric oxide
    • Kimura H, Weisz A, Ogura T, Hitomi Y, Kurashima Y, Hashimoto K, D'Acquisto F, Makuuchi M, Esumi H: Identification of hypoxia-inducible factor 1 ancillary sequence and its function in vascular endothelial growth factor gene induction by hypoxia and nitric oxide. J Biol Chem 2001;276:2292-2298.
    • (2001) J Biol Chem , vol.276 , pp. 2292-2298
    • Kimura, H.1    Weisz, A.2    Ogura, T.3    Hitomi, Y.4    Kurashima, Y.5    Hashimoto, K.6    D'Acquisto, F.7    Makuuchi, M.8    Esumi, H.9
  • 23
    • 0030460724 scopus 로고    scopus 로고
    • Hypoxia response elements in the aldolase A, enolase 1, and lactate dehydrogenase A gene promoters contain essential binding sites for hypoxia-inducible factor 1
    • Semenza GL, Jiang BH, Leung SW, Passantino R, Concordet JP, Maire P, Giallongo A: Hypoxia response elements in the aldolase A, enolase 1, and lactate dehydrogenase A gene promoters contain essential binding sites for hypoxia-inducible factor 1. J Biol Chem 1996;271:32529-32537.
    • (1996) J Biol Chem , vol.271 , pp. 32529-32537
    • Semenza, G.L.1    Jiang, B.H.2    Leung, S.W.3    Passantino, R.4    Concordet, J.P.5    Maire, P.6    Giallongo, A.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.